• Journal of Pharmaceutical Investigation
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• 제10권3호
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• pp.27-32
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• 1980

This paper was to investigate the biovailability of antipyrine, ampicillin and protein binding in pathological rats and rabbits pretreated with typhoid vaccine. The results are as follows: The absorption of antipyrine and ampicillin respectively were reduced in rats pretreated with typhoid vaccine as compared with those of normal rats. Especially absorption of ampicillin was more decreased than those of antipyrine. The blood level of antipyrine in severe state was decreased but in mild state. Blood level of ampicillin was decreased in mild state as well as in severe state. Relative bioavailability of antipyrine and ampicillin were mostly decreased in rabbits pretreated with typhoid vaccine except that of antipyrine in mild state. Renal clearance of antipyrine was not affected, but that of ampicillin was apt to increase. Protein binding of antipyrine and ampicillin were decreased by high concentration of typhoid vaccine.

• 전기학회논문지
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• 제62권9호
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• pp.1249-1254
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• 2013

A torque control algorithm suitable for detecting an open circuit failure in which one of the three phases is unable to supply power to a motor in the permanent magnet synchronous motor is presented in this paper. When the failure occurs in the inverter, the output torque of motor is restricted. A new method which is implemented by using only a processor algorithm internally without any hardware redundancy circuit is proposed. A simulation and experimental study is carried out with a three phase inverter system to show the validity of the proposed method.

• 동의신경정신과학회지
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• 제20권4호
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• pp.173-183
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• 2009

Objectives : This study was designed to report the effect of Korean traditional treatment and progressive muscle relaxation for insomnia. Methods : We treated two patients scored more than 15 point at insomnia severity index by korean traditional treatment and progressive muscle relaxation. Results : After treatment, sleep duration and sleep quality was improved. Insomnia Severity Index, Pittsburgh Sleep Quality Index score were decreased. Conclusions : We may conclude that korean traditional treatment and progressive muscle relaxation is effective in patients with insomnia.

• Journal of Pharmaceutical Investigation
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• 제26권2호
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• pp.113-117
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• 1996

This study was attempted to investigate the pharmacokinetic interaction between sodium valproate (4, 8, 16 mg/kg, i.v.) and phenytoin (4 mg/kg, i.v.) in rabbits. The plasma concentration and area under the curve (AUC) of phenytoin were increased significantly (p<0.05, p<0.01) when coadministered with sodium valproate (4, 8, 16 mg/kg) in rabbits. The volume or distribution and total body clearance of phenytoin were decreased significantly (p<0.05, p<0.01) when coadministered with sodium valproate (8, 16 mg/kg) in rabbit. From the results of this experiment, it is desirable that dosage regimen of phenytoin should be adjusted and therapeutic drug monitoring should be performed for reduction of side or toxic effect when phenytoin will be coadministered with sodium valproate in clinical use.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2000년도 정기총회 및 학술대회
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• pp.21-26
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• 2000

이 논문은 아날로그 CATV망을 이용하여 디지털 TV신호를 전송할 때의 성능을 연구하였다. 디지털 전송성능을 분석하기 위하여, 디지털 전송시스템은 DVB-C 규격을 적용하였으며, 채널손상요소로는 랜덤잡음과 극소반사(microreflection)를 고려하였다. 극소반사에 대한 모델링은 미국 CableLab사에서 측정한 값을 적용하였으며, 극소반사의 영향을 최소화하기 위해서 수신단에서 블라인더 등화기를 적용하였다. 전송성능은 $E_b/N_0$에 대한 BER과 MSE를 이용하여 표현하였다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2011년도 한국컴퓨터종합학술대회논문집 Vol.38 No.1(A)
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• pp.484-487
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• 2011

본 논문에서는 다양한 조명 조건 하에 노출되어 있는 무선 이동 로봇으로부터 전송 받은 영상에서 충분한 정보를 포함하고 있는 영상과 그렇지 않은 영상을 식별하는 방법을 제안한다. 열악한 조명 조건하에서 획득된 영상은 많은 잡음을 포함하고 있고, 충분한 주변 정보를 제공해 줄 수가 없다. 따라서 본 논문에서는 무선 이동 로봇으로부터 전송 받은 영상을 전처리하여 획득한 이진 영상의 복잡도를 이용하여 전송받은 영상을 식별하는 방법을 제안한다. 본 실험에는 무선 이동 로봇으로부터 획득한 305개의 실험 영상을 이용하여 실험을 실시하였고, 실험 결과, 약 97%의 식별율을 나타내었다.

• Journal of Pharmaceutical Investigation
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• 제20권1호
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• pp.1-5
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• 1990

Effect of an angiotensin inhibitor (AAS; loading dose of 25, 50, $100{\mu}g/kg$ and maintenance dose of 12.5, 25,$50{\mu}g/ka/hr$) on the pharmacokinetics of propranolol (4 mg/kg i.v.) was studied in rabbits. Plasma concentrations and relative bioavailability of propranolal increased upto 127-175% by AAS coinjection. The urinary excretion of propranolol decreased by AAS. Dosage regimen of propranolol should be adjusted when it is administered with AAS.

• Journal of Pharmaceutical Investigation
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• 제14권1호
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• pp.11-18
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• 1984

This paper was attempted to study on the effect of metoclopramide or propantheline on the absorption rate and bioavailability and pharmacokinetic parameter of fluorouracil in rats and rabbits. The result are as follows; Metoclopramide increased the absorption rate of fluorouracil but propantheline decreased in situ experiment with rat small intestine. Metoclopramide increased the blood level and relative bioavailability and absorption rate constant of fluorouracil in rabbits. Prolonged the peak blood level (tmax) and decreased the absorption rate constant (Ka) but did not affect the blood level and relative bioavailability of fluorouracil in rabbits. As a matter of fact, it is considerd that the coadministration of metoclopramide or propantheline is more desirable than the single administration of fluorouracil for available dosage regimen.

• 약학회지
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• 제34권6호
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• pp.401-406
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• 1990

The Pharmacokinetics of furosemide (5 mg/kg iv) was investigated in rabbits with folate (75 mg/kg, 150 mg/kg 300 mg/ug, iv) induced renal failure. The plasma concentration was increased and urinary excretion was decreased significantly compared with those of normal rabbits. ${\alpha},\;{\beta}\;and\;K_{12},\;K_{21},\;K_{10}$ were decreased, $t_{1/2}$ and AUC were increased significantly. Correlation of serum creatinine concentration and AUC, renal clearance have linear relationship respectively. In short, dosage regimen of furosemide is considered to be adjusted in the dose size and the dosing interval by degree of serum creatinine concentration.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2004년도 춘계학술발표회
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• pp.985-994
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• 2004

The application of the reinforced retaining wall has increased in the last 10 years in Korea. The height of reinforced wall is generally limited to less than 15m. It has been reported that the reinforced wall higher than 10m should have higher strength reinforcement or should reduce the lateral earth pressure of the reinforced wall to secure the stability of the wall. In this study, the reinforced retaining wall was constructed 14m high, backfilled by a mixture of soil and cement and instrumented on the reinforcement elements. The instrumented reinforced wall was monitored during and after construction. Field monitoring result shows that a backfill by a mixture of soil and cement reduced the tensile stress developed on the reinforcing elements and the reinforced wall backfilled by a mixture of soil and cement performed successful.