• YAKHAK HOEJI
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• v.46 no.4
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• pp.290-294
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• 2002

Cephradine is an orally absorbed cephalosporin with a broad spectrum of activity against gram-positive and gram-negative bacteria and is highly resistant to beta-lactamase degradation. The purpose of the present study was to evaluate the bioequivalence of two cephradine capules, Cephradine capsule (Donggu Pharmaceutical Co., reference drug) and Cephradine capsule (Shinpoong Pharmaceutical Co., test drug), according to the guidelines of Korea Food and Drug Administration. Twenty-six normal volunteers, 24.6 $\pm$ 3.70 years in age and 62.4 $\pm$ 8.99 kg in body weight, were divided into two groups and a randomized 2 $\times$ 2 cross-over study was employed. After one capsule containing 250 mg of cephrdine was orally administered, blood was taken at predetermined time intervals and the concentrations of cephrdine in serum were determined using HPLC with UV detector. The pharmacokinetic parameters such as AU $C_{t}$ to $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in AUCt, $C_{max}$ and $T_{max}$ between two products were 2.89％, 1.05％ and 1.06％, respectively, when calculated against the reference drug. The 90％ confidence intervals were within log0.8 $\leq$ $\delta$ $\leq$ log1.25 (e.g., log0.9803 $\leq$ $\delta$ $\leq$ log1.0734 and log0.9674 $\leq$ $\delta$ $\leq$ log1.220 for AU $C_{t}$, and $C_{max}$, respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Cephradine capsules (Shinpoong Pharmaceutical Co.) is bioequivalent to Cephradine capsules (Donggu Pharmaceutical Co.).o.).o.).).o.).

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.23 no.2
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• pp.45-49
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• 2017

Background: The purpose of this study was to investigate the effect of structured cryotherapy on edema of patients who had a total knee arthroplasty (TKA). Methods: The subjects were 58 patients who were diagnosed with osteoarthritis and had total knee arthroplasty in D hospital. In total, 29 people were in the leg elevation cryotherapy group (LECTG), 29 people were in the control group (CTG). After TKA, the patients' swelling on post operation days (POD) 3 were checked. After the post OP checking, LECTG was treated with cryotherapy with leg elevation for 12 days but CTG was cryo therapy with sit on chair. Results: Swelling show significant difference within the group (p<.05), but did not show signigicant difference between groups (p>.05). Conclusions: Base on the results, it was found the cryo therapy of $-78^{\circ}C$ improved swelling after TKA. Accordingly, it is thought that cryo therapy of $-78^{\circ}C$ has positive effect on swelling in the process of recovery after operation. but It did not approve that the leg elevation was even more effective. For this study, the reserch developed to enhance the effectiveness of the cryotherapy, would make it possible to apply to an effective cryotherapy posture.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.23 no.2
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• pp.27-32
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• 2017

Background: The purpose of this study was to compare the effects of IASTM and static stretching techniques on ankle joint range of motion (ROM), static foot pressure. Methods: Twenty four subjects with gastrocnemius shortness participated in this study. The subjects were assigned randomly to one of two groups: The soft tissue mobilization technique (IASTM) group received intervention using a IASTM instrument for two minutes, and the stactic stretching group performed self stretching for 30 seconds, four times. The ROM of the ankle joint was measured by active ankle dorsi-flexion test, and a TPScan was utilized to collect the plantar foot pressure. This experiment was performed by two physical therapists. The significant level was set at ${\alpha}=.05$. Results: The results were as follows: 1) The ROM of the ankle joint and was significantly increased in both groups. 2) Plantar foot pressure was no significant in both groups. 3) There were no significant differences between the IASTM group and static stretching group for any variable. Conclusions: The results of this study suggest that static stretching is an effective and easy technique for restoring proper muscle length in subjects with gastrocnemius shortness. We recommend that static stretching technique be used for treat gastrocnemius shortness in clinical setting and home program.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.14 no.1_2
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• pp.117-123
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• 1992

Malignant fibrous histiocytoma rarely occurs in the jaws. A case of malignant fibrous histiocytoma originated from the maxillary sinus is reported with review of literature. A 59-year-old woman visited the Chonnam University Hospital in March, 1990, with chief complaint of swelling and tenderness in the right cheek. Radiographic findings revealed wide destruction of the maxilla. The biopsy taken from the maxilla showed histopatholgic findings of malignant fibrous histiocytoma. Accordingly the patient received preoperative and postoperative anticancer chemotherapy by the modified CY-VA-DIC protocol of the Southwest Oncology Group (SWOG). Preoperative and postoperative radiotherapy were also given to her in total 40Gy of $^{60}Co$ And she underwent radical resection of the maxilla. No evidence of recurrence or metastasis was shown for 2-year period of postoperative follow up.

• PNF and Movement
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• v.11 no.2
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• pp.9-19
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• 2013

Purpose : Study on the effects of attention(working memory) for normal adults by applying transcranial Direct Current Stimulation(tDCS). Methods : There are two groups of 10 random people aged between 20 to 30, one is an experimental group(stimulation) and the other is a comparison group(simulate stimulation). For the 1st da y, pre-stimulation test is executed, and for the 2nd day to the 4th day, tDCS is applied stimulated both on the right prefrontal lobe and the left occipital lobe through the electrode. The stimulation lasts for 15 minutes with voltage power of 1mA for each day. The post-stimulation test is executed on the day of 5th. In this paper, a FAIR attention test is used for measuring the attention. Results : As the result of the experiment, there are significant gaps both on the value of P, the ability of selective attention, and the value of C, the consistent ability after the stimulation on right prefrontal and left occipital lobe. And there is no significant gap on the value Q, the quality(Control). However, all the P, Q, and C values are increased according to the average value between the pre-stimulation test and the post-stimulation. Conclusion : Finally, ability of selective attention and self-control, and consistent attention is progressed by applying the tDCS to the normal people.

• PNF and Movement
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• v.11 no.1
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• pp.27-33
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• 2013

Purpose : The purpose of this research was to research on Needs for the Construction of the CSFT(Cluster with a Strongpoint for Field Training) on students and professors of health-related majors. Methods : We investigated 164 students and professors using a self-reporting method with experience of Field Training. A statistical analysis was performed using SPSS 17.0 for window version. Results : It showed that educational satisfaction had scored 4.05 in curriculum, 4.00 in environment, 3.52 in schedule, 3.71 in evaluation and 3.71 in teaching and 3.84 in industrial-college systems for Field Training. Needs for the Construction of the CSFT had scored 4.17 in $mean{\pm}standard$ deviation. Conclusion : Characterization of Nursing, Department of Health and local health care environment and conditions, if you think the quality of education for the Department of Health Nursing, gradually, the acquisition and improvement of the base hospital is necessary. Therefore, it is considered to be institutionalized by installing the strongpoint hospital at least one in each region, so that they can contribute to the improvement of people's health.

• PNF and Movement
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• v.11 no.1
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• pp.69-78
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• 2013

Purpose : This study was to investigate the satisfaction of clinical practice according to medical institute. Methods : A survey was administered for 70 college students with experience in clinical practices. We investigated using a questionnaire on 'curriculum factors on practice', 'environmental factors on practice', 'time-schedule factors on practice', 'teaching factors on practice'. A statistical analysis was performed using SPSS 17.0 for window version. Results : 1. The degree of satisfaction on curriculum of clinical practice was higher college hospital than other hospital in 3 among 5 items(p<.05). 2. The degree of satisfaction on environmental factors of clinical practice was higher school hospital than other hospital in 4 among 6 items(p<.05). 3. The degree of satisfaction on time-schedule factors of clinical practice was higher college hospital than other hospital in 1 among 5 items(p<.05). 4. The degree of satisfaction on teaching factors of clinical practice was higher college hospital than other hospital in 4 among 6 items(p<.05). Conclusion : It was revealed by this survey that the satisfaction of clinical practice in school hospital had higher other hospital in curriculum, environment and teaching factors. To maximize the effects of clinical practice, a clinical practice program in school hospital is required and further research and attention are suggested.

• Korean Journal of Head & Neck Oncology
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• v.37 no.1
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• pp.47-51
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• 2021

Papillary thyroid carcinoma (PTC) typically has a good prognosis, but it frequently metastasizes to the regional lymph nodes. Although survival impact of lymph node metastasis is not clear, complementary treatment is generally added after surgery when lymphatic metastasis exists. Several previous studies have reported that the multifocal PTC is associated with poor prognosis and requires selective neck dissection to prevent regional lymph node metastasis, but they are under controversy. In this study, we present a 24-year-old female patient, diagnosed as PTC with intrathyroidal spread and regional lymph node metastases. Intrathyroidal spread of PTC can only be observed microscopically and is believed to have the similar origin of unicentric multifocal PTC. As multifocal PTC is highly associated with regional lymph node metastasis and requires an additional treatment, PTC with intrathyroidal spread may follow a similar clinical course and treatment plan. Here we report the case with a brief literature review and expect its attribution to further academic interest of treatment choice.

• Journal of Industrial Convergence
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• v.20 no.8
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• pp.163-172
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• 2022

Public officials are volunteers for the people, and the police are in charge of the safety of the people. In particular, the marine safety of Korea, which has three sides of the sea, is very important. The education of maritime police is a very important factor due to the specificity and risk of the sea. In particular, since the new curriculum is linked to the job while in office, factors related to educational performance are more important. In this study, the relationship between personality characteristics and academic burnout was examined for 200 new maritime police officials. Among the five factors of personality characteristics, extroversion factors, neurotic factors, and emotional exhaustion factors were extroversion factors, neurotic factors, and cynicism factors, and extroversion factors, neurotic factors, and integrity factors. In particular, the five factors of personality characteristics that have the greatest influence on academic burnout were neurotic. For the educational satisfaction and effectiveness of the new maritime police officer, it is necessary to minimize the psychological margin and stress of the new maritime police officer.

• Journal of the Korean Society of Radiology
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• v.9 no.4
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• pp.227-234
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• 2015

In this paper, we studied possibility about application for CAD on diffuse liver disease through pixel texture analysis parameters(average gray level, skewness, entropy) which based statistical property brightness histogram and image analysis using brightness difference liver and kidney parenchyma. The experiment was set by ROI ($50{\times}50$ pixels) on liver ultrasound images.(non specific, fatty liver, liver cirrhosis) then, evaluated disease recognition rates using 4 types pixel texture analysis parameters and brightness gap liver and kidney parenchyma. As a results, disease recognition rates which contained average brightness, skewness, uniformity, entropy was scored 100%~96%, they were high. In brightness gap between liver and kidney parenchyma, non specific was $-1.129{\pm}12.410$ fatty liver was $33.182{\pm}11.826$, these were shown significantly difference, but liver cirrhosis was $-1.668{\pm}10.081$, that was somewhat small difference with non specific case. Consequently, pixel texture analysis parameter which scored high disease recognition rates and CAD which used brightness difference of parenchyma are very useful for detecting diffuse liver disease as well as these are possible to use clinical technique and minimize reading miss. Also, it helps to suggest correct diagnose and treatment.