• Title/Summary/Keyword: 이진상

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Proteomic Changes in Odae Polished White Rice Grown at Different Cultivation Conditions (재배환경에 따라 변화하는 오대벼 백미의 단백질체 분석)

  • Lee, Ju-Young;Lee, Jin-Woo;Kim, Young-Ran;Yeom, Yu-Jin;Lim, Jin-Kyu
    • Journal of Applied Biological Chemistry
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    • v.55 no.2
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    • pp.79-83
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    • 2012
  • It has been known that the proteome profiles in the period of growth and development of rice are changed by the growth conditions including temperature, soil, and fertilization. In this study, the proteome profiles of Odae polished white rice grown in Chulwon and Chilgog were compared on 2-dimensional(D) gels. The differentially expressed proteins were selected from the 112 identified total proteins and classified into functional groups. The most significantly differentially expressed proteins were stress responsive proteins; Ent-kaur-16-ene synthase, which is responsible for synthesizing a plant hormone gibberellin, was expressed in Chulwon rice and heat shock proteins were in Chilgog rice, respectively. Xylanase inhibitor protein, which inhibits the enzyme xylanase produced by pathogenic fungi and Bacilli, was expressed significantly high in Chilgog rice grown at high temperature. Differential expressions of transporter proteins were observed both in Chulwon and Chilgog rice. Regarding the facts that Chilgog rice contained relatively higher amount of proteins than Chulwon rice and Chulwon rice showed large number of proteins were differentially expressed, it can be concluded that different cultivation conditions could change the protein expression profiles in rice in various ways, including elevation of protein amount or differential expressions of specific proteins, etc. The results suggest that the characteristics of the profiles of the proteome in the polished white rice are definitely changed by the environmental factors including high temperature. The results can be utilized for the development of the proper cultivation conditions for the production of high quality rice with good palatability.

Analysis of Hematological Factor to Predict Plaque of the Carotid Artery in Ultrasound Images (경동맥초음파에서 죽상경화반을 예측하는 혈액학적 수치의 분석)

  • Yang, Sung Hee;Kang, Se Sik;Lee, Jinsoo
    • Journal of the Korean Society of Radiology
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    • v.10 no.3
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    • pp.187-193
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    • 2016
  • In this study, we performed the carotid artery ultrasound targeting 140 subjects who have conducted to evaluate the changes in intima-media thickness(IMT) and plaque correlated with the presence or absence of a hematological test of the carotid artery. Considering that the IMT thickness more than 1mm is abnormal based on the carotid artery ultrasound to assess the presence or absence of plaque, and examined the correlation by classifying the blood lipid value and the fasting blood glucose level through the serum test. Consequently, the fasting blood glucose level is being analyzed as independent predictors of causing dental plaque(p=0.033), cut off value was determined as 126 mg/dL(sensitivity 56.25%, specificity 68.38%) in ROC curve analysis. Furthermore, the odds ratio appeared 1.01 times the value in the Logistic regression. Therefore, it seemed that the necessity to prospective studies in a number of subjects are considered, and also taking into account a number of blood test values along with the sonography of the carotid artery as a valuable part for effective primary prevention and follow-up observation of the cardiac and brain vascular disease is highly recommended.

Genetic Diagnosis of Beckwith Wiedemann Syndrome using Methylation Specific PCR-RFLP Method (Methylation Specific PCR-RFLP 방법을 이용한 Beckwith Wiedemann Syndrome의 진단)

  • Kim, Gu-Hwan;Lee, Jin-Joo;Choi, Seung-Hoon;Lee, Joo-Yeon;Lee, Beom-Hee;Yoo, Han-Wook
    • Journal of Genetic Medicine
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    • v.7 no.2
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    • pp.133-137
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    • 2010
  • Purpose: Beckwith-Wiedemann syndrome (BWS) is an overgrowth malformation syndrome caused by a methylation abnormality at chromosome 11p15, consisting of two imprinting centers, BWSIC1 (IGF2, H19) and BWSIC2 (LIT1, KvDMR). This study evaluated the applicability of a methylation-specific (MS) PCR RFLP method for the genetic diagnosis of BWS. Materials and Methods: A total of 12 patients were recruited based on clinical findings. Karyotyping was performed using peripheral blood leukocytes, and genomic DNA was treated with bisulfate and amplified using methylation-specific primers. RFLP was conducted with restriction enzymes in differentially methylated regions of LIT1, H19, and IGF2. Results: The 12 BWS patients had normal karyotypes. Abnormal methylation patterns in the BWSIC2 (LIT1) region were identified in seven patients (58.3%) using the MS-PCR RFLP method. Conclusions: The MS-PCR RFLP method is a simple, economical genetic test. It detected genetic abnormalities in 50-60% of BWS patients, suggesting that it can be used as a screening test. A more precise method is required, however, to enhance the detection rate of genetic abnormalities, especially in BWSIC1 region.

A Study on Isoelectric Point and Softness of an Ethylene Oxide Adducted Amphoteric Surfactant (에틸렌 옥사이드가 부가된 양쪽성 계면활성제의 등전점 및 유연력에 관한 연구)

  • Lim, JongChoo;Park, JunSeok;Han, DongSung;Kim, JiSung;Lee, Seul;Mo, DaHee;Lee, JinSun
    • Applied Chemistry for Engineering
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    • v.23 no.6
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    • pp.521-528
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    • 2012
  • In this study, we analyzed the physical properties of an ethylene oxide adducted amphoteric surfactant such as critical micelle concentration, surface tension, interfacial tension, contact angle, viscosity and phase behavior. The dual function characteristics of an amphoteric surfactant were investigated by determining an isoelectric point, which were attained using zeta potential measurements and quartz crystal microbalance (QCM) experiments. The isoelectric points of DE3-OSA82-AO, DE5-OSA82-AO and DE9-OSA82-AO surfactant systems determined by zeta potential measurements were 6.97, 6.93 and 7.10 respectively and they are in good agreement with the isoelectric point values measured by QCM experiments. The frictional property measured using an automated mildness tester showed that the DE-OSA82-AO surfactant could provide a good softening effect at neutral condition.

Solvent Extraction of Rare Earth Elements (La, Ce, Pr, Nd, Sm) from Hydrochloric Acid Solutions using Cyanex 572 (염산용액에서 Cyanex 572에 의한 희토류 원소(La, Ce, Pr, Nd, Sm)의 용매추출)

  • Cho, Yeon-Chul;Kang, Myeong-Sik;Ahn, Jae-Woo;Lee, Jin-Young
    • Resources Recycling
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    • v.25 no.6
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    • pp.50-57
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    • 2016
  • This work was examined the extraction and stripping behavior of rare earths (La, Ce, Pr, Nd, Sm) from the hydrochloric acid solution by Cyanex 572 and compared to the results that of PC88A. Experimental parameters such as equilibrium pH, extractant & strip reagent concentration were observed and extraction percentage, distribution coefficient, stripping percentage and the separation factor of the adjacent element were analyzed. The $pH_{50}$ values was more higher using Cyanex 572 than that of PC88A. As the increase of the extractant concentration, the distribution coefficient of rare earth elements was increased. Stripping percentage of rare earth elementss from the Cyanex 572 was 85% to 95% and PC88A showed 80% to 87%. Separation factor of Ce/La, Ce/Pr, Pr/Nd, Nd/Sm was enhanced about 1.0-5.0 using Cyanex 572 as an extractant in mixture solution.

Extraction & Separation Behavior of Light Rare Earth Elements from the Mixed Solutions by Cyanex 572 (경희토류(La, Ce, Pr, Nd, Sm) 혼합용액에서 Cyanex 572에 의한 추출·분리 거동 고찰)

  • Cho, Yeon-Chul;Lee, Joo-Eun;So, Hong-Il;Ahn, Jae-Woo;Kim, Hong-In;Lee, Jin-Young
    • Resources Recycling
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    • v.26 no.4
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    • pp.79-87
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    • 2017
  • Extraction and separation behaviors of La, Ce, Pr, Nd and Sm from light rare earth multi - component mixed solutions by Cyanex 572 were studied. As extractant concentration increased, the $pH_{50}$ values of all the five components decreased. When extractant concentration was larger than 0.6 M, the separation factor of La and Ce, Nd and Sm was higher than 10, while the separation factor between Ce and Pr, Pr and Nd was as low as 0.5~2.2. Addition of TBP to the 0.6 M Cyanex 572 had little synergistic effect on the phase separation rate and separation factor. From the analysis of experiment results, group separation of [La]/[Pr, Nd, Sm] and [Pr, Nd]/[Sm] could be possible, but in case of the group separation between [La, Ce] and [Pr, Nd] was not available because of the low separation factor between Ce and Pr.

A Moderating Effect of Help-Seeking in the Relationship between Violence in sports, Depression, and Intention to Sport Continuance among Female Athletes (여성선수의 운동부 내 폭력 피해경험과 우울, 운동지속의사의 관계에서 도움요청(Help-Seeking)의 완충효과)

  • Kim, Jae Yop;Lee, Jeen Suk;Choi, Sun Ah
    • Korean Journal of Social Welfare Studies
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    • v.43 no.1
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    • pp.59-87
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    • 2012
  • The purpose of this study is to understand the effect of violence in sports on intention to sport continuance among female athletes and to analysis the mediating effect of depression and the difference groups according to help-seeking. In order to accomplish these purposes, this study surveyed from September to October in 2010. The final subjects in the analysis were 345 female athletes who are belong to school athletic team, professional team, business team, and national team. The data were analyzed with SPSS 18.0 and AMOS 10.0 for conducting multiple group analysis. The main results of this study are as follows; First, those who were suffered by emotional violence were 62.4%; those who are damaged by physical violence were 28.6% among the participants in this study. In case of intention to sport continuance, when measured by a rule of five, was average 3.15. 29.9% of the female athletes scored above the standard of depression. Second, depression turned out to have a partial mediating effect within the relationship where violence in sports has effect on intention to sport continuance. Third, between experimental and non-experimental group on help-seeking among female athletes, there was a statistically significant difference in the structural relationship. This means that help-seeking has moderating effect within the path of violence in sports affecting depression. Based on the results, this study suggested that there is a strong need for intervention for the both prevention and cure of the sports violence. It is necessary to develop preventive programs and coping strategies on female athletes' depression and intention to sport continuance.

Determining Kinetic Parameters and Stabilization Efficiency of Heavy Metals with Various Chemical Amendment (중금속 안정화제의 반응 매개변수 결정 및 중금속 안정화 효율성 평가)

  • Oh, Se-Jin;Kim, Sung-Chul;Kim, Tae-Hee;Yeon, Kyu-Hun;Lee, Jin-Soo;Yang, Jae-E.
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.6
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    • pp.1063-1070
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    • 2011
  • In this study, total of 5 different chemical amendments were evaluated for determining kinetic parameters and stabilization efficiency of heavy metals in aqueous phase. Standard solution of Cd and Pb ($100mg\;L^{-1}$) was mixed with various ratio of amendments (1, 3, 5, 10%) and heavy metal stabilization efficiency was monitored for 24hrs. All examined amendments showed over 90% of removal efficiency for both Cd and Pb except zerovalent iron (ZVI) for Cd (43-63%). Based on result of heavy metal stabilization efficiency, it was ordered as $CaCO_3$ > Dolomite > Zeolite > Steel slag > ZVI for both Cd and Pb in aqueous phase. For kinetic study, first order kinetic model was adapted to calculate kinetic parameters. In terms of reaction rate constants (k), zeolite showed the fastest reaction rate (k value from 0.4882 for 1% to 2.0105 for 10%) for Cd and ZVI (k value from 0.2304 for 1% to 0.5575 for 10%) for Pb. Considering reaction rate constant and half life for heavy metal stabilization, it was ordered as Zeolite > $CaCO_3$ > Dolomite > Steel slag > ZVI for Cd and $CaCO_3$ > Dolomite > Steel slag > Zeolite > ZVI for Pb. Overall result in this study can be interpreted that lime containing materials are more beneficial to remove heavy metals with high efficiency and less time consuming than absorbent materials.

Classifying Sub-Categories of Apartment Defect Repair Tasks: A Machine Learning Approach (아파트 하자 보수 시설공사 세부공종 머신러닝 분류 시스템에 관한 연구)

  • Kim, Eunhye;Ji, HongGeun;Kim, Jina;Park, Eunil;Ohm, Jay Y.
    • KIPS Transactions on Software and Data Engineering
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    • v.10 no.9
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    • pp.359-366
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    • 2021
  • A number of construction companies in Korea invest considerable human and financial resources to construct a system for managing apartment defect data and for categorizing repair tasks. Thus, this study proposes machine learning models to automatically classify defect complaint text-data into one of the sub categories of 'finishing work' (i.e., one of the defect repair tasks). In the proposed models, we employed two word representation methods (Bag-of-words, Term Frequency-Inverse Document Frequency (TF-IDF)) and two machine learning classifiers (Support Vector Machine, Random Forest). In particular, we conducted both binary- and multi- classification tasks to classify 9 sub categories of finishing work: home appliance installation work, paperwork, painting work, plastering work, interior masonry work, plaster finishing work, indoor furniture installation work, kitchen facility installation work, and tiling work. The machine learning classifiers using the TF-IDF representation method and Random Forest classification achieved more than 90% accuracy, precision, recall, and F1 score. We shed light on the possibility of constructing automated defect classification systems based on the proposed machine learning models.

Risk Assessment of Semiconductor PR Process based on Frequency Analysis of Flammable Material Leakage (반도체 PR 공정의 인화성 물질 누출 빈도분석을 통한 위험성 평가)

  • Park, Myeongnam;Chun, Kwang-Su;Yi, Jinseok;Shin, Dongil
    • Journal of the Korean Institute of Gas
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    • v.25 no.5
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    • pp.1-10
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    • 2021
  • Semiconductor Photo Resist (PR) automation equipment uses a mixture of several flammable substances, and when it leaks during the process, it can lead to various accidents, therefore, risk assessment is necessary. This study analyzed the frequency of leakage of Acetone and PGMEA used in PR automation equipment and the frequency at which such leakage could lead to a fire accident through the frequency analysis method, and evaluated the need for additional risk reduction measures in the current facility. Based on the process leak data and ignition probability data of IOGP, leak frequency analysis and ignition probability were derived, and the frequency of actual fire accidents was analyzed by combining them. The frequency of material leakage in semiconductor PR process is 7.30E-03/year, and fire accidents can occur by acetone that exists above the flash point when the material is leaked, the frequency was calculated at the level of 1.24E-05/year. According to the UK HSE, for a major accident occurring with a frequency of 1.24E-05/year, it is defined as "Broadly Acceptable", a level that does not require additional measures for risk reduction when it causes 7 or less deaths, and due to the process operated by two people, no additional risk reduction are required.