• Title/Summary/Keyword: 이준구

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Adhesion of Human Intervertebral Disk Cells on Aiginate/PLGA Microspheres (Alginate/PLGA 미립구에 대한 인간디스크 세포 부착 효과)

  • Lee, Jun-Hee;Jang, Ji-Wook;So, Jeong-Won;Choi, Jin-Hee;Park, Jong-Hak;Ahn, Shik-Il;Son, Young-Suk;Min, Byoung-Hyun;Khang, Gil-Son
    • Polymer(Korea)
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    • v.33 no.1
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    • pp.7-12
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    • 2009
  • PLGA microspheres have been known as an injectable system for tissue engineering. The purpose of this study was to investigate the condition of emulsion formation and cell adhesion on the microsphere surface. BSA-loaded PLGA microsphere was fabricated by oil-in-water (O/W) and water-in-oil-in-water (W/O/W) solvent evaporation method. Sodium alginate was dissolved in water phase to control initial burst release and to improve lag time by PLGA bulk degradation. In addition, the morphology of cells attached on the micro spheres was studied using a scanning electron microscopy (SEM). Cellular proliferation behavior of human disc cells cultivated on PLGA micro spheres was analyzed using a MTT assay. MTT assay revealed that the cells can attach and proliferate on PLGA microspheres. According to these results, we concluded that BSA -loaded alginate/PLGA microspheres can be used as an injectable system for tissue engineering application.

Quality Characteristics and Potentialities of Sugar-snap Cookies with Red Ginseng Powder (홍삼 분말 첨가 Sugar-Snap Cookie의 제조 및 품질특성)

  • Park, Hyang-Suk;Lee, Myung-Ho;Lee, Jun-Youl
    • Culinary science and hospitality research
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    • v.17 no.1
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    • pp.171-183
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    • 2011
  • This research is to figure out the manufacture proper1ies and the effect of adding red ginseng powder into cookies. When adding red ginseng powder into wheat, there was no significant change in moisture content while the amount of WRC and AWFC increased significantly. In the manufacturing and quality characteristics, there was no noticeable change in thickness and spreadability. Also, wheat cookies containing red ginseng powder didn't show significant differences either and the control plot had the biggest diameter. The change of chromaticity showed that L-value and b-value seemed to significantly decrease while a-value increased a lot In other words, the more ginseng powder was added, the darker its external colour became. In the organic characteristics, the control plot showed the best result in volume, crust, top grain and in almost every part. The volume had the most satisfying result with 6% of red ginseng powder added, and there was not much difference among the groups added with red ginseng powder. Generally, adding up tp 12% of ginseng powder was found best when making cookies.

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Development of the Global Tsunami Prediction System using the Finite Fault Model and the Cyclic Boundary Condition (유한 단층 모델 및 순환 경계조건을 이용한 전지구 지진해일 예측 시스템 개발)

  • Lee, Jun-Whan;Park, Eun Hee;Park, Sun-Cheon;Woo, Seung-Buhm
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.27 no.6
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    • pp.391-405
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    • 2015
  • A global tsunami prediction system was suggested for a distant tsunami using a finite fault model and a cyclic boundary condition. The possibility of the suggested system as a distant tsunami response system was checked by applying it into the case of 2014 Chile tsunami. A comparison between the numerical results(tsunami height and arrival time) with different conditions (boundary condition, governing equation, grid size and fault model) and measured data (DART buoy, tide station) showed the importance of the finite fault model and the cyclic boundary condition.

Growth, Yield, and Leaf-macronutrient Content of Grafted Cherry Tomatoes as Influenced by Rootstocks in Semi-forcing Hydroponics (반촉성 수경재배시 대목에 따른 방울토마토 접목묘의 생육, 수량 및 엽 내 양분 함량)

  • Hyewon Lee;Hyo Bong Jeong;Jun Gu Lee;Indeok Hwang;Deok Ho Kwon;Yul Kyun Ahn
    • Journal of Bio-Environment Control
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    • v.32 no.1
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    • pp.40-47
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    • 2023
  • There are many different types of cultivation in tomatoes for year-round production. One of them, semi-forcing cultivation is characterized by growing seedlings in winter season. If grafted seedlings are used in winter season that energy cost can be reduced, because they have tolerance to cold stress. This study was conducted to analyze the rootstock performance by measuring the growth, yield, and leaf-macronutrient content of cherry tomatoes grown in semi-forcing hydroponics. Three domestic rootstocks 'HSF4', '21LM', '21A701', and a control cultivar 'B-blocking' were grafted onto jujube-shaped cherry tomato (Lycopersicon esculentum L.) commercial cultivar 'Nonari'. The total yield per plant with grafted cherry tomato '21A701' was 3,387g, which was 11%, 22% and 24% higher than the yield with 'B-blocking', non-grafted one and 'HSF4'. The stem diameter of '21A701' was thick with 8.26mm, whereas non-grafted one was thin with 7.23mm at 160 days after transplanting. The flowering position of '21LM' was 34% and 47% higher than the flowering position of 'B-blocking' and non-grafted one at 153 days after transplanting. The NO3-N concentration in petiole sap of '21LM' was the highest with 1,746mg·L-1 and non-grafted one and 'HSF4' were the lowest with 1,252mg·L-1 and 1,245mg·L-1 at 167 days after transplanting. The results indicated that rootstock/scion combinations in cherry tomatoes can affect the plant growth, yield, and the concentration of different NO3-N in leaves at the late growth stage. Both '21A701' and '21LM' have vigorous root system, which influence the growth and yield increased.

Case report of bilateral facial cleft and duplicated maxilla (양측성 안면열과 중복 상악골:증례보고)

  • Eom Min-Yong;Song Min-Seok;Kim Hyeon-Min;Koo Hyun-Mo;Yi Jun-Kyu;Jeong Jong-Sun;Na Joo-Il
    • Korean Journal of Cleft Lip And Palate
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    • v.8 no.1
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    • pp.23-29
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    • 2005
  • The facial cleft and duplicated maxilla are lire congenital anomaly. After Rushton and Walker had reported a unilateral facial cleft with excess tooth and bone formation in 1937, few authors described similar cases. The etiology of this anomaly is not well understood, but considered embryologically as a neurocristopathy. A neurocristopathy is defined as a condition arising from aberrations in early migration, growth and differentiation of neural crest cells. This aberrations result in facial malformation such as facial clefts and loss or duplication of facial structures. We experienced a male newborn baby with bilateral facial cleft and duplicated maxilla. The cleft was surgically corrected when he was 5 months old. The function and appearance of lip are improved. Duplicated maxilla will be surgically removed. We report this case with review of literatures.

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A Case of Hemophagocytic Lymphohistiocytosis in a Child with Systemic Lupus Erythematosus (전신성 홍반성 루푸스 환아에서 병발한 혈구 탐식성 조직구 증식증 1례)

  • Hwang, Ja Young;No, Suk Man;Lee, Jin;Jang, Pil Sang;Kim, Young Hoon;Kim, Jin Tack;Lee, Joon Sung
    • Clinical and Experimental Pediatrics
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    • v.46 no.10
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    • pp.1029-1031
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    • 2003
  • Hemophagocytic lymphohistiocytosis is a reactive disorder characterized by a generalized non-malignant histiocytic proliferation with prominent hemophagocytosis by stimulated histiocytes in the bone marrow and reticuloendothelial systems resulting in pancytopenia and liver dysfunction. Several diseases including infection, malignancy and autoimmune disease are known to be causative disorders. This case demonstrated histiocytic hemophagocytosis in the bone marrow, resulting in pancytopenia during treatment of systemic lupus erythematosus and did not show any underlying disease.

Brightness uniformity measurement analysis of the medical clinical monitoring (의료용 임상 모니터의 휘도 균일성 측정 방법 분석)

  • Kim, Seon-chil;Baek, Su-min;Lee, Jun-seok
    • Korean Journal of Digital Imaging in Medicine
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    • v.17 no.1
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    • pp.57-60
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    • 2015
  • 병원에서 사용되는 임상용 모니터의 관리는 중요하다. 모니터의 기본적 관리는 휘도이며, 휘도에서도 균일도가 가장 먼저 관리되는 대상이다. 특히 LCD 모니터인 경우 균일도에 문제가 모니터의 교체주기와 일치하는 경우가 많다. 휘도에 대한 평가는 여러 가지가 존재하지만, 본 연구에서는 AAPM TG18에 따라 TG18-UNL10, TG18-UNL80을 이용하여 휘도의 균일도를 조사하였다. 이 조사과정에서 측정값 중 가장 높은 수치를 기준으로 나머지 값의 편차를 구하는 방법과 평균값을 이용하여 측정값의 편차를 구하는 방법 두 가지를 사용하였으며, 두 가지 방법의 유의성을 알아보고자 휘도의 편차 변화량 즉, 균일도를 측정하였다. 휘도 균일도의 정량평가는 향후 모니터의 관리에 가장 큰 영향을 미치는 인자로써 측정기간 중 변화량은 매우 적게 나타났다. 따라서 본 연구에서 제시된 최대, 최소값의 편차나 평균값의 상대 편차값 모두 유의한 결과를 얻을 수 있었다.

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공장산 매실고추장 반제품의 숙성 중 화학적 특성변화에 관한 연구

  • 이은주;박양식;이승욱;이준호
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.177-177
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    • 2003
  • 고품질 기능성 고추장을 개발하는데 고추장의 품질은 사용하는 재료, 배합비율, 제조방법, 숙성조건등에 따라 맛과 향기, 색 등에서 차이가 나타난다. 시장경쟁력에 맞추어 공장산 고추장에 기능성을 강화시키고 소비자의 기호성을 충족하기 위해 유기산과 비타민, 무기질이 풍부하고 다양한 생리적 기능성을 가진 국내산 매실엑기스를 공장산 고추장의 품질에 영향을 미치는 반제품에 농도별로 (0%(M0), 10%(M10), 20%(M20), 30%(M30)) 첨가하여 숙성 시 일어나는 화학적 성분변화를 조사하였다. 환원당은 9.6∼10.3%에서 11.9∼12.8%로 증가하였으며 매실엑기스의 첨가 농도가 낮을수록 높은 값을 나타내었다. 아미노산성질소는 숙성이 진행됨에 따라 증가하였으며 매실엑기스가 첨가된 시료의 경우 그 변화폭이 큰 것으로 나타났다. M0(대조구)의 pH는 5.45에서 발효 중 미생물에 의한 유기산생성으로 다소 감소하였으나 M10, M20, M30은 매실에 들어있는 유기산과 키토산으로 초기 pH가 2.87∼3.38로 낮아 변화 폭은 적은 것으로 나타났다. 적정산도는 숙성기간 중 증가하였으며, 대조구에 비해 메실엑기스의 첨가농도가 증가할수록 높은 값을 보였다. 염분(NaCl)은 같은 기간 중 감소하였으며 매실엑기스의 농도가 증가할수록 낮은 수치를 보였다.

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Effects of Cutting Frequency and Level of Fertilizer Application on Forage Productivity at Alpine Grassland of 600 m Altitude (고랭지 표고 600m에서 예취횟수와 시비수준이 목초의 생산성에 미치는 영향)

  • Sung Kyung Il;Kim Gon Sik;Lee Jun Woo;Kim Byung Wan;Lee Jong Kyung;Jung Jong Won
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.25 no.2
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    • pp.137-142
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    • 2005
  • This study was conducted to evaluate the effects of cutting frequency and level of fertilizer application on the botanical composition and forage yield of alpine pasture. Field experiment was established at 600 m (a.s.1) altitude with two cutting frequency schedules (two and three times annually) and two levels of fertilizer application (lower level of fertilizer, 200-200-200 kg / ha and standard level of fertilizer, 280-200-240 kg / ha; N, $P_2O_5$ and $K_2O$, respectively). Higher grass to clover ratio was observed in two cutting frequencies. The clover ratio was highest as $16\%$ in thee cutting frequencies with lower level of fertilizer application End the ratio of weed was low in all treatments ($3.7 {\~} 6.7\%$). No significant difference was observed in forage dry matter (DM) yield among treatments, however forage DM yield in three cutting frequencies tended to be greater in standard level of fertilizer application compared to lower level of fertilizer application. The forage quality was greater in three cutting frequencies, but not changed with different levels of fertilizer application. This result indicates that three cutting frequency and standard level of fertilizer application system are considered to be proper management methods at alpine grassland of 600 m altitude considering the botanical composition, forage DM yield md forage quality.

Quality Characteristics of Kochujang Prepared with Maesil (Prunus mume) Extract during Aging (매실추출액 첨가 고추장의 숙성 중 품질특성 연구)

  • Lee, Min-Ji;Lee, Jun-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.5
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    • pp.622-628
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    • 2006
  • Kochujang was prepared with various concentrations of Maesil extracts (0, 1, 2, and 5%) and the physicochemical characteristics of Maesil extracts added Kochujang ('Maesil Kochujang') were investigated during aging of 100 days. pH decreased slightly during aging. Titratable acidity, on the other hand, increased with aging, reaching at the highest level at the 40 days of aging and then decreased slowly. The changes of moisture content were complicated in the beginning, but after 60 days it increased slowly. The water activity decreased but salt concentration increased consistently in all samples during aging. L* and a*-values decreased during aging and L*, a*, and b*-values decreased significantly with high amount of Maesil extract in the sample. Soluble solid contents increased slowly while reducing sugar contents increased for up to 40 days and then decreased. Amino nitrogen contents increased steadily after 40 days of aging and they reached at $230.00{\sim}246.00mg%$ upon 100 days of aging.