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The Revised Korean Practice Parameter for the Treatment of Attention-Deficit Hyperactivity Disorder (II) - Diagnosis and Assessment - (주의력결핍 과잉행동장애 한국형 치료 권고안 개정안(II) - 진단 및 평가 -)

  • Lee, Moon-Soo;Park, Su-Bin;Kim, Gyung-Mee;Kim, Hyun-Jin;Park, Sangwon;Kim, Yunsin;Lee, Young Sik;Kweon, Yong-sil;Shin, Dongwon
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.28 no.2
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    • pp.58-69
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    • 2017
  • Attention-deficit hyperactivity disorder (ADHD) is a highly prevalent, impairing, and comorbid disorder that persists into adulthood. ADHD should be diagnosed in the same manner as other common adult mental health disorders. The three most important components in the comprehensive evaluation of patients with ADHD are the clinical interview, medical examination, and completion and scoring of behavior rating scales. The diagnostic evaluation of ADHD should include questions about the symptoms, family history, prior evaluation and treatment of ADHD, as well as other problems including alcohol and drug use. Screening interviews or rating scales, as well as interviews, should be used. When it is feasible, clinicians may wish to supplement these components of the evaluation with the objective assessments of the ADHD symptoms, such as through psychological tests. These tests are not essential to reaching a diagnosis, however, or to treatment planning, but may yield further information about the presence and severity of cognitive impairments that could be associated with some cases of ADHD. As comorbidity is the rule rather than the exception, clinicians should carefully screen for comorbid disorders as part of a comprehensive assessment of ADHD. To receive a diagnosis of ADHD, the person must be experiencing significant distress or impairment in his or her daily functioning, and must not meet the criteria for other mental disorders which might better account for the observed symptoms, such as mental retardation, autism or other pervasive developmental disorders, mood disorders and anxiety disorders. This report aims to suggest practice guidelines for the assessment and diagnosis of children, adolescents and adults with ADHD in Korea.

Acute Toxicity of Ammonia on Juvenile banded Catfish(Pseudobagurus fulvidraco) (동자개 치어의 암모니아 급성 독성)

  • SOHN, Sang-Gyu;LEE, Joo-Yong;LEE, Young-Sik;KIM, Kwang-Seog;KIM, Bong-Rae;LEE, Jeong-Ho;CHOI, Hye-Sung
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.5
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    • pp.1229-1235
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    • 2015
  • Juvenile banded catfish(Pseudobagurus fulvidraco, mean length $10.7{\pm}0.42cm$ and mean weight $15.0{\pm}0.23g$) were exposed to varies TAN(total ammonia) concentrations at pH levels of $6.12{\pm}0.51$, $7.00{\pm}0.26$ and $8.04{\pm}0.07$ for 96hrs to check the level of acute toxicity on biofloc technology aquaculture system(BFT). The result showed that cumulative mortalities for juvenile banded catfish at TAN levels 48.95, 55.96, 66.47, and 78.88 mg/L at pH $6.12{\pm}0.51$ were 0, 30, 30, and 50%, respectively. At pH $7.00{\pm}0.26$, its mortalities to TAN 5.20, 11.68, 15.31, and 18.31 mg/L were 0, 10, 20, and 70%, respectively and at pH $8.04{\pm}0.07$, the mortalities to TAN 0.96, 1.49, 2.13, and 3.62 mg/L were 10, 20, 40, and 100%, respectively. Its $96h-LC_{50}$ (median lethal concentration, $LC_{50}$) at pH $6.12{\pm}0.51$, $7.00{\pm}0.26$, and $8.04{\pm}0.07$ were 78.12, 15.87, and 2.21 mg/L for TAN, and 0.05, 0.10, and 0.14 mg/L for $NH_3$, respectively, and the acute toxicity for ammonia to juvenile banded catfish increased exponentially with increase of pH.

Effect of a Low-oxygen Layer on the Vertical Distribution of Zooplankton in Gamak Bay (가막만 동물플랑크톤의 수층 분포에 미치는 저산소화의 영향)

  • Yong, Moon-Seong;Soh, Ho-Young;Choi, Sang-Duk;Jung, Chang-Soo;Kim, Sook-Yang;Lee, Young-Sik
    • Korean Journal of Environmental Biology
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    • v.24 no.3
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    • pp.240-247
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    • 2006
  • The dynamic of zooplankton community and its relationship with dissolved oxygen were studied at the Soho area of Gamak Bay from 22 August to 15 September in summer. We found that zooplankton were in low abundance or absent from bottom waters when oxygen concentrations were <3 mg $L^{-1}$. The relationship between summer low-oxygen in bottom-layer and zooplankton community structure was discussed at vertical abundance in Soho area of Gamak Bay. To examine effects of bottom-layer low-oxygen on abundance and vertical distributions in the stratified Soho area, zooplankton was surveyed near-surface, within the near-bottom in the study area under a range of near-bottom dissolved oxygen conditions. There were vertical variation in total zooplankton abundance in the study area (ANOVA, P<0.05). Overall abundance of zooplankton: copepod nauplii, Oithona sp. and tintinnids were lower throughout the water column when bottom-layer DO was low (${\leq}3mg\;L^{-1}$). In this context it was postulated that zooplankton distribution in the Soho area of Gamak Bay might be controlled by dissolved oxygen condition.

A Survey of Sexual Dysfunction by Antidepressants (항우울제와 연관된 성기능 장애에 대한 조사)

  • Cho, Sung-Il;Lee, Young-Sik;Suh, Dong-Soo;Na, Chul;Min, Kyung-Jun
    • Korean Journal of Psychosomatic Medicine
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    • v.11 no.1
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    • pp.44-51
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    • 2003
  • Objectives: Antidepressants are frequently associated with sexual dysfunction. Especially, there were few report of sexual dysfunction related with venlafaxine and mirtazapine in Korea. The purpose of this survey was to evaluate the frequency and nature of sexual dysfunction related with selective serotonin reuptake inhibitors(SSRIs), venlafaxine and mirtazapine by the use of specific questionaires. Methods: In one hundred twenty two patients, sexual dysfunction was investigated cross-sectionally by using The questionaires for sexual dysfunction, which includes questions about decreased libido, delayed orgasm or ejaculation, premature ejaculation or orgasm, absence of orgasm or ejaculation, erectile dysfunction in men/vaginal lubrication dysfunction in women, sexual pain and patient's tolerance of the sexual dysfunction. BDI was also measured. Sexual dysfunction was analyzed in association with the duration and the dose of medications and the severity of depression. Results: The incidence of sexual dysfunction during antidepressants use in our survey was 37.7%. There were no difference of incidence in sexes(p=.746). In comparison of paroxetine, venlafaxine and mirtazapine, there were no significant differences of the incidence(p=.065) and the severity of any type of sexual dysfunction. Conclusion: Although there were no significant differences of sexual dysfunction in our survey, sexual dysfunction may be closely associated with antidepressants. Further prospective study of sexual dysfunction should be needed.

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Anxiety, Impulsiveness, and Drinking Problems in Employed Women (직장 여성의 불안, 충동성과 음주문제)

  • Lee, Hyun Jae;Han, Doug Hyun;Lee, Young Sik;Kee, Baik Seok;Kwon, Hye Jin;Park, Doo Byung
    • Anxiety and mood
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    • v.7 no.2
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    • pp.73-78
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    • 2011
  • Objectives : This study examined drinking habits, anxiety, and impulsiveness in employed women. Methods : We sampled 925 residents aged over 20 years in Gwanak-gu of Seoul. In the process, we divided subjects into employed women and unemployed women groups and then used the Korean Version of Alcohol Use Disorder Identification Test (AUDIT-K), State-Trait Anxiety Inventory (STAI), and Barratt Impulsiveness Scale (BIS) to identify patterns in subjects' alcohol drinking, anxiety and impulsiveness. Results : Among the 925 respondents, 95.7% drank alcohol, and after the analysis, female problematic drinking ($12{\leq}AUDIT-K{\leq}25$) and alcohol dependence ($AUDIT-K{\geq}26$) was apparent in 61 (9.5%) and 2 respondents (0.3%), respectively. Female respondents who had jobs tended to drink more and exhibit higher ratios of problematic drinking, with a higher exposure to alcohol than those that were unemployed. The psychological attributes related to female respondents' alcohol problems related to state of anxiety and impulsiveness. Employed women respondents also showed a higher state of anxiety and impulsiveness than unemployed women. Conclusion : Controlling the frequency of exposure to alcohol, anxiety, and impulsiveness in employed women should be considered to be crucial controlling factors related to the hazards of excessive drinking.

Sports Psychiatry (스포츠 정신의학)

  • Han, Doug-Hyun;Na, Chul;Lee, Young-Sik
    • Korean Journal of Psychosomatic Medicine
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    • v.12 no.2
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    • pp.95-102
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    • 2004
  • Backgrounds: It was thought that sport was related with mentality. Compared to psychology, psychiatry has so far paid rather little attention to athletes. In this overview, I attempted to introduce the ideas of various observers of sports with the view of clinical psychiatry and summarized basic principle role of psychiatrist. Results and Discussions : To understand the athletic frame of mind, it is helpful to observe athletes in their psychologic development and when we do so we can quickly see trends that are not apparent by observing mature athletes alone. Psychobiology of sport would discuss some of the endogenous neurochemicals(hormone, neurotransmitter) that may be part and parcel of the athlete's psychiatric status. The psychological problems that frequently interfere with training and competition may be divided into five categories 1) choke, 2) slump, 3) injury, 4) interpersonal problem, 5) training dilemma. Psychiatric problem also arise in athletes like general people. various method for psychiatric patients like psychotherapy, group therapy, family systems perspective, and pharmacotherapy could been applied to sports psychiatry. Conclusions Although the contribution of sports psychiatry to sport is clinical one, psychiatrist's interest in role and conflict of athlete would enhance the molding of humanistic athletes who enjoy their life and sports.

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Studies on the Elasticity, Young Modulus, and Breaking Tension of the Tympanic Membrane in Dog (고막(鼓膜)의 탄성도(彈性度)와 파열장력(破裂張力)에 관(關)한 연구(硏究))

  • Lee, Young-Shik
    • The Korean Journal of Physiology
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    • v.2 no.1
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    • pp.39-45
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    • 1968
  • Recently, in this department, pressure-displacement curve and breaking tension of dog and human tympanic membrane were studied using intact, fresh or dried tympanic membrane attached to external auditory meatus. However, physical property, proper elasticity-Young Modulus, of the tympanic membrane has not been clarified yet. Present study is attempted to further clarify proper Young Modulus of tympanic membrane, and to distinguish possible difference between layer of stratum radiatum and layer of stratum circulare of tympanic membrane in breaking tension and in Young Modulus. Tympanic membrane was excised from sacrificed dog, and preparation was made into the size of approximately 1 mm in width and 3 mm in length. In fresh or dried tympanic membrane, which was dried at $80^{\circ}C$ for 24 hrs., some preparations were made along the long axis parallel to the fibers of radial direction, and others were made along the long axis perpendicular to the radial fibers-circular direction. Breaking tension and displacement according to loading, were measured and Young Modulus was calculated in tympanic membrane preparations under the different experimental conditions. Results obtained are summarized as follows : 1. Young Modulus of fresh tympanic membrane in radial direction was $6.57{\times}10^8\;dyne/cm^2$, and that of fresh preparation in circular direction was $1.68{\times}10^8\;dyne/cm^2$. The Young Modulus of fresh tympanic membrane in radial direction resembles to that of silk and whale moustache. In dried tympanic membrane, Young Modulus of preparation of radial direction was $30.2{\times}10^8\;dyne/cm^2$ and that of preparation in circular direction was $25.0{\times}10^8\;dyne/cm^2$. 2. Breaking tension of fresh tympanic membrane was 44.9 gm/mm in radial preparation, and 7.9 gm/mm in circular preparation. In dried tympanic membrane, breaking tension was 46.7 gm/mm in preparation of radial direction, and 17.2 gm/mm in preparation of circular direction. 3. Much smaller breaking tension of the circular preparation-one fifth to the radial preparation-seemed to be responsible for the higher incidence of circular fiber breaking in tympanic membrane performation caused by trauma or sudden change in atmospheric pressure. 4. The correlation seemed to be very close between breaking tension and Young Modulus in tympanic membrane.

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Acute Toxicity of Nitrite on Juvenile Banded Catfish(Pseudobagurus fulvidraco) (동자개 치어의 아질산 급성 독성)

  • Sohn, Sang-Gyu;Lee, Young-Sik;Kim, Kwang-Seog;Lee, Han-Na;Lee, Joo-Yong;Back, Sun-Jung
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.1
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    • pp.41-48
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    • 2015
  • Juvenile banded catfish(Pseudobagurus fulvidraco, mean length $10.4{\pm}0.37cm$ and mean weight $14.5{\pm}0.46g$) were exposed to several nitrite(${NO_2}^-$) concentrations for 96h at pH levels of $6.18{\pm}0.54$, $6.5{\pm}0.30$ and $7.07{\pm}0.22$. The result showed that cumulative mortalities of fish to ${NO_2}^-$ levels of 12.4, 19.8, 33.9 and 53.6 mg/L at pH levels of $6.18{\pm}0.54$ were 20, 25, 40 and 85%, respectively. At pH $6.5{\pm}0.54$, mortalities to ${NO_2}^-$ 22.4, 36.4, 45.3 and 63.2 mg/L were 25, 35, 50 and 100%, respectively. At pH $7.07{\pm}0.22$, mortalities to ${NO_2}^-$ 25.5, 45.7, 56.3 and 66.4 mg/L were 0, 55, 70 and 100%, respectively. The 96h-$LC_{50}$(median lethal concentration, $LC_{50}$) of fish to several ${NO_2}^-$ concentrations at pH levels of $6.18{\pm}0.54$, $6.5{\pm}0.30$ and $7.07{\pm}0.22$ were assessed in these experiments. 96h-$LC_{50}$ at pH levels of $6.18{\pm}0.54$, $6.5{\pm}0.30$ and $7.07{\pm}0.22$ were 32.68, 40.49 and 45.85 mg/L, respectively. It indicated that acute toxicity of ${NO_2}^-$ to juvenile banded catfish increased with low levels of pH and lengthening of exposure time to ${NO_2}^-$. In particular, smaller fish(mean weight $14.5{\pm}0.46g$) were more sensitive to ${NO_2}^-$ than larger fish(mean weight $81.7{\pm}1.42g$; not published). The 96h-$LC_{50}$ of juvenile banded catfish to ${NO_2}^-$ would be primary guideline for water quality management in the intensive culture system such as RAS and BFT.

CHARACTERISTICS OF UNRULY & DELINQUENT ADOLESCENTS ADMITTED TO A PSYCHIATRIC INPATIENT UNIT (청소년 병동에 입원한 비행 청소년의 특성에 관한 연구)

  • Lee, Young-Sik;Kim, Wun-Jung;Carey, Michael
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.8 no.1
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    • pp.70-82
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    • 1997
  • Objective:This study was performed to identify and understand the characteristics of adolescents who had a history of police arrest and/or were adjudicated unruly/delinquent by the juvenile court. Method:The study employed a retrospective reivew of coumputer-recorded data set on 210 consecutive admissions to an adolescent psychiatric inpatient unit. Three groups(No Police Contact, N=115;Police Contact Only, N=60;Adjudicated, N=35) were compared on the areas of a) cognitive and educational performance b) emotion:anxiety, depression, suicidality c) personality d) family and life experiences. Standardized assessments were administered to all subjects using WISC-Ⅲ, Kaufman Test of Educational Achievement, Millon Adolescent Personality Inventory, Reynolds Adolescent Depression Scale, Revised-Chilren’s Manifest Anxiety Scale, Suicide Ideation Questionnarie, Suicide Behavior Interive, Life Events Checklist, and Family Environmental Scale. A subgroup of the subjects, 60 cases also received a standardized interview by Child Assessment Schedule. Results:The characteristic findings of the delinquent group(the police contact only and adjudicated subjects combined) included (1) a high rate of adoption, sexual promiscuity, out of home placement, and repeated psychiatric hospitalization, (2) low verbal IQ scores and educational achievements, (3) high impulsivity, low social conformity, and high forcefulness in personality inventory, (4) low activityrecreation orientation and low moral religious emphasis in family environment, (5)a high frequency of adverse life experiences, (6) among 3 groups, the Police Contact Only group showed the lowest depression, anxiety and suicidal ideation scores, (7) a high diagnostic frequency of conduct disorder, ODD, and ADHD. Conclusions:The adolescent psychiatric inpatients with a delinquent history presented with a certain clinical, family, psychometric characteristics that warrant specific clinical intervention strategies for their cognitive deficits, an impulsive personality style, family dysfunction with adverse life experiences and disruptive behavioral disorders, different from the rest of adolescent psychiatric inpatients.

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SEASON OF BIRTH, BIRTH ORDER AND MATERNAL AGE IN INFANTILE AUTISM (유아(幼兒) 자폐증(自閉症)의 출생계절(出生季節), 출생순위(出生順位)및 산모연령(産母年齡)에 관한 연구(硏究))

  • Lee, Young-Sik;Min, Kyung-Joon;Choi, Jin-Sook;Kim, Dong-Hyun;Cho, Soo-Churl;Lee, Kil-Hong;Hong, Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.4 no.1
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    • pp.46-53
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    • 1993
  • To find some involvement of environmental factors in autism, season of birth, birth order, and maternal age at birth of autistic children were investigated Total number of clinical outpatient autistic children was 357, which consisted of 319 male and 38 female, then male-to-female sex ratio was 8.4 to 1, and all subjects were born during $1986{\sim}1988.$ These data were compared with those of controlled general populations. The results were as follows : 1) In monthly and seasonal distributions of birth, autistic children were not different from normal control 2) Comparing with control group by Slater's and Greenwood-Yule's birth order calculation methods, there was no significant difference in birth order of autistic children 3) The maternal ages at birth in autistic group were significantly higher than those of control group(P<01) 4) High-risk pregnancies were significantly frequent in autistic group compared with control group(p<01)Our study supported the idea that at least some environmental factors, especially at-risk pregnancy, are involved in autism causation.

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