• Journal of Life Science
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• v.18 no.9
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• pp.1219-1224
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• 2008

The embryonic zebrafish (Danio rerio) is rapidly becoming an important model organism for studies of early events in vertebrate development. Neural crest-derived pigment cell precursors of the embryonic zebrafish give rise to melanophores, xanthophores, and/or iridophores. Cell-signaling mechanisms related to the development of pigmentation and pigment pattern formation remain obscure. In this study, zebrafish embryos were treated with various signaling-related molecules - LiCl (an inositol-phosphatase inhibitor), forskolin (a protein kinase-A activator), a combination of LiCl/forskolin, and LiCl/heparin (an IP3 inhibitor) in order to identify the mechanisms involved in pigmentation. LiCl treatment resulted in ultrastructural and morphological alterations of melanophores. To identify the possible proteins responsible for this ultrastructural and morphological change, phosphorylation patterns in vitro and in vivo were analyzed. LiCl and LiCl/forskolin treatment elicited dramatic increases in the phosphorylation of a 55-kDa protein which was inhibited by heparin treatment. LiCl treatment also induced phosphorylation of a 55-kDa protein in melanophores purified from adult zebrafish. Collectively these results suggest that a LiCl-induced 55-kDa phosphoprotein plays a role in melanophore morphology and ultrastructure and ultimately effects gross pigmentation.

• Journal of the Korea Society of Computer and Information
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• v.11 no.2 s.40
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• pp.187-199
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• 2006

This paper proposes the design of user centric pavilion information guide system based on mobile device such as PDA. which is composed of system interface factors as user wants. The suggested information guide system is convenient for user carrying because it is based on PDA mobile device and the used liquid browser system makes all data information displayed on a small screen in contrast with the other browser system. Indeed, factors of system interface can be re-composed by user interaction. And this system can effectively provide the detail information about the exhibited objects as various media data such as text, image, voice, music, video etc. The proposed system is made up of media database server. mobile system control server and mobile system interface which accepts user interaction and displays the information. Each system is networked based on TCP/IP and uses XML (extensible Markup Language) and JAVA 2 micro edition to be able to update data. This feature enhances a wide use to be able to load this system on the any mobile device.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.05a
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• pp.609-611
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• 2010

IPTV(Internet Protocol Television)is the point in commercial and broadcast content from the numerous channels that are growing exponentially, Many people with mobile devices anywhere, anytime you want to use IPTV, demand will increase. Numerous channels for collecting information about EPG (Electronic Program Guide) service, IP (Internet Protoco) communications using a fast search of content for broadcast EPG is time to take advantage of the service. Using the current wired network, the Android-based IPTV services to take advantage of the EPG in the mobile environment to provide an environment being studied, and Country of the European digital broadcast standard DVB-MHP standard is followed by subsequent research and development of the EPG service is required. In this study, using the existing wired network, IPTV EPG service information of the channel in a mobile environment user-friendly as possible by providing channels for EPG service information to users quickly and easily search for content to provide an environment and Android-based mobile IPTV environment to take advantage of the EPG service channels of broadcast channels with in the EPG service for users to gather information retrieval system is proposed.

• Journal of KIISE:Information Networking
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• v.30 no.3
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• pp.377-386
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• 2003

In this paper, we present an application layer protocol to support secure wireless Internet services, called Application Layer Security(ALS). The drawbacks of the two traditional approaches to secure wireless applications motivated the development of ALS. One is that in the conventional application-specific security protocol such as Secure HyperText Transfer Protocol(S-HTTP), security mechanism is included in the application itself. This gives a disadvantage that the security services are available only to that particular application. The other is that a separate protocol layer is inserted between the application and transport layers, as in the Secure Sockets Layer(SSL)/Transport Layer Security(TLS). In this case, all channel data are encrypted regardless of the specific application's requirements, resulting in much waste of network resources. To overcome these problems, ALS is proposed to be implemented on top of HTTP so that it is independent of the various transport layer protocols, and provides a common security interface with security applications so that it greatly improves the portability of security applications. In addition, since ALS takes advantages of well-known TLS mechanism, it eliminates the danger of malicious attack and provides applications with various security services such as authentication, confidentiality integrity and digital signature, and partial encryption. We conclude this paper with an example of applying ALS to the solution of end-to-end security in a present commercial wireless protocol stack, Wireless Application Protocol.

• Journal of the Korean Society for Railway
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• v.19 no.4
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• pp.456-467
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• 2016

Wireless Access in Vehicular Environments (WAVE) communication technology, which provides vehicleto-vehicle and vehicle-to-infrastructure communication and offers safe and convenient service, has been developed for application to an Intelligent Transport System (ITS). This paper provides field test results on a study of the feasibility of WAVE technology application to railway communication systems. A test railway communication system based on WAVE technology has been built along the Daebul line and a newly developed EMU. Field tests have been carried out according to the communication function requirements for LTE - R. The test results show that the railway communication system based on WAVE technology meets the functional requirements: maximum transmission length is 730m, maximum transfer delay is 5.69ms, and maximum interruption time is 1.36s; other tests including throughput test, video data transmission test, VoIP data test, and channel switching test also produced results that meets the functional requirements. These results suggest that WAVE technology can be applied to the railway communication system, enabling Vehicle-to-Wayside communication.

• Journal of the Korea Institute of Military Science and Technology
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• v.24 no.6
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• pp.645-654
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• 2021

In this paper, we proposed a protocol to convert 2W telephone analog signals to Ethernet data in a private PSTN 2W tactical voice system. There are several kinds of operational problems in the tactical telephone network where 2W telephone copper lines are installed hundreds of meters away from the PBX in a headquarter site. The reason is that it is difficult to install and maintain the 2W telephone copper cable in severe operational fields and to meet safety and stability operational requirements of the telephone line under lighting and electromagnetic environments. In order to solve these challenging demands, we proposed an efficient method that the 2W analog interface signals between a private PBX system and a 2W telephone is converted to Ethernet messages using the optical Ethernet data communication network already deployed in the tactical weapon system. Thus, it is not necessary to install an additional optic cable for the ethernet telephone line and to maintain the private PSTN 2W telephone network. Also it provides safe and secure telecommunication operation under lightning and electromagnetic environments. This paper presents the conversion protocol from 2W telephone signals over Ethernet interface between PBX systems and 2W telephones, the mutual exchange protocol of ethernet messages between two converters, and the rule to process analog signal interface. Finally, we demonstrate that the proposed technique can provide a feasible solution in the tactical weapon system by analyzing its performance and experimental results such as the bandwidth of 2W telephone ethernet network and the transmission latency of voice signal, and the stability of optic ethernet voice network along with the ethernet data network.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.26 no.3
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• pp.254-261
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• 2000

The present study has attempted to look into the mechanism of ras-induced carcinogenesis in a human epithelial cell system. Human epithelial cells immortalized with Ad12-SV40 hybrid virus were used to assess carcinogenic potential of the ras-oncogene. Cells transfected with pSV2-ras showed characteristics of cellular transformation. The transformation parameters such as cell density, soft-agar colony formation, and cell aggregation were significantly increased in the cells expressing ras oncoprotein. In addition, the duration required for the appearance of foci was shortened in the ras-transfected cells. Consistent with other reports, our results demonstrated an evidence that the ras-oncogene induced the cellular transformation of human epithelial cell system. When a high concentration of glucocorticoid was added into the media, transformation process was accelerated. It is speculated that glucocorticoid may provide an advantageous environment for the proliferation of the transformed cells. The induction of the intracellular free calcium concentrations following agonist treatment was significantly lower in the transformed cells than in the control cells. These effects were more manifested in the presence of extracellular cacium, indicating that the transformation process may alter the influx pathway of extracellular calcium. The induction of $IP_3$ following agonist treatment was also lower in the transformed cells than in the control cells. Thus, it is suggested that phospholipase C-coupled pathway was down-regulated in the process of the ras-induced transformation. While the levels of $TGF-{\beta}_1$ and PAI-2 mRNAs were decreased, the level of fibronectin mRNA was increased. The results indicate that mechanism of the ras-induced transformation may be associated with the altered expressions of growth regulatory factors. The present study demonstrates an evidence that the ras-induced cellular transformation may be associated with alteration of signal transduction and growth regulatory factors. The study will contribute to improve the understanding of molecular mechanism of epithelium-derived cancers including oral cancer.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.8B
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• pp.492-501
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• 2007

UMTS-WLAN interworking approach can make the best use of the advantages of both networks by eliminating the stand-alone defects of the two services. For the interworking mechanisms of WLANs and UMTS networks, two major solutions have been proposed, namely loose coupling and tight coupling. The loose coupling approach provides separate data paths for WLAN and UMTS. On the other hand, the tight coupling provides a full integration of the WLAN network and the UMTS core network. The loose coupling has been preferred due to the simplicity and less reconfiguration requirement. However, loose coupling is worse in seamless mobility, QoS provision, and network security. In order to lessen the problems involved in the UMTS-WLAN interworking approaches, we propose a new interworking network architecture and a fast vertical handover scheme by employing Mobility Anchor(MA) for interworking between the two different networks. MA can enable authentication and session initialization before L2 handover of the mobile terminal, so that the seamless and fast vertical handover become possible. Thru analysis and numerical experiments, we proved that the proposed scheme has been validated.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06d
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• pp.217-219
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• 2006

4G mobile networks are expected to support various multimedia services over IP networks and also satisfy high spectral efficiency requirement. In cellular systems including 4G networks, hotspot cells can occur when available wireless resources at some location are not enough to sustain the needs of users. The hotspot cell can potentially lead to blocked and dropped calls, which can deteriorate the service quality for users. In a 4G mobile network, a band of users enjoying multimedia services can move around, which may generate heavy flows of traffic load. This situation can generate the hotspot cell which has a short life span of only a few minutes. In this paper, we propose a handover-based scheme which can effectively manage hotspot cells in 4G mobile networks. With the scheme, the current serving cell can recognize the load status of the target cell in advance before handover execution. Adaptive handover time control according to the amount of traffic load of cells can effectively and flexibly manage the hotspot cell in the network. And, through our hotspot cell management scheme, acceptable service quality can be supported as users continuously maintain connections with the network. In the simulation results, we find that our scheme generates smaller number of hotspot cells and supports higher service quality than the compared schemes.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.11
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• pp.63-71
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• 2003

This paper suggests the packet loss recovery method to communicate in real time in the Internet. To reduce the effects of packet loss, Forward Error Correction (FEC) that adds redundant information to voice packets can be used. Adaptive Multi Rate Wideband(AMR-WB) codec which is recently selected by the Third Generation Partnership Project(3GPP) for GSM and the third generation mobile communication WCDMA system and has also been standardized in ITU-T for providing wideband speech services is used. The major cause for speech qualitly degradation in IP-networks is packet loss. So, We recovered single lossy packet by using FEC method and concealed continued errors. The proposed scheme if evaluated in the Gilbert Internet channel model. The high quality of audio maintained up to 30% packet loss.