• Progress in Medical Physics
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• v.2 no.2
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• pp.149-154
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• 1991

We have designed and applied the calibrationmethod of $\^$90/Sr Ophthalmic Applicaton by measuring the electron currents. We considered the number of electrons which is emitted from the source, the area of the source, and the electron stopping power in the water, and those data were used for calculation. Film was used for evaluating the accurate source area. Average electron stopping power was obtained by analyzing ${\beta}$-ray energy spectrum. We compared between the result from our method and that from the TLD measurements. The calibration result from our method shows 63.3 ${\pm}$5.1 cGy/sec, while 50.7${\pm}$7.3 cGy/sec from TLD measurement. But the supplier's specification tells 46.89.4cGy/sec.

• Progress in Medical Physics
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• v.12 no.2
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• pp.141-146
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• 2001

It is well known that assurance of the radiation therapy needs for an accuracy of $\pm$ 5 % in the delivery of an absorbed dose to target volume. Therefore, the dose evaluation of brachytherapy source and/or linear accelerate beam must be a stability with accuracy. In an advanced country, they recommended to use the radioactive check source for reference air ionization chamber for a stable response of radiation field chamber. In this experiments, the radioactive source Sr-90 and PR-05 air ionization chamber were used for standard source and reference ion chamber. The response of reference ion chamber showed as an 1.000$\pm$ 0.010 uncertainty for 10 years long and the evaliuation f dose discrepancy of clinical field ion chamber showed as 0.997 $\pm$0.011 in a $^{60}$ Co brachytherapy soruce. In our experiments, we can assuarance the long halflife standard source is reliable to preserve the calibration factor of reference chamber in stability.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2004.11a
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• pp.91-95
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• 2004

Several MRI studies have reported reductions in temporal lobe volumes in Alzheimer's disease (AD). Measures have been usually obtained with regions-of-interest (ROI) drawn manually on selected medial and lateral portions of the temporal lobes, with variable choices of anatomical borders across different studies. We used the automated voxel-based morphometry (VBM) approach to investigate gray matter abnormalities over the entire extension of the temporal lobe in 10AD patients (MM5E 22)and 22 healthy controls. Foci of significantly reduced gray matter volume in AD patients were detected in both medial and lateral temporal regions, most significantly in the right and left posterior parahippocarmpal gyri. At a more flexible statistical threshold (P<0.01, uncorrected for multiple comparisons), circumscribed foci of significant gray matter reduction were also detected in the right amygdala/enthorinal cortex, the anterior and posterior borders of the superior temporal gyrus bilaterally, and the anterior portion of the left middle temporal gyrus. These VBM results confirm previous findings of temporal lobe atrophic changes in AD, and suggest that these abnormalities may be confined to specific sites within that lobe, rather than showing a widespread distribution.

• Progress in Medical Physics
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• v.17 no.4
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• pp.232-237
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• 2006

The aim of this study was to develop the calculation algorithm of source strength of Ir-192 source In terms of the absorbed dose to water instead of an apparent activity (Ci). For this work the Multi Purpose Brachytherapy Phantom(MPBP) was developed, which was designed to locate the source and the chamber precisely at a specific position Inside the water phantom. The reference point of measurement was set at the 5 cm distance along the transverse axis of the source. For a brachytherapy source calibration, the absorbed dose to water calibration factor ($N_{D.W.Q}$) of an lonization chamber were determined and then apply standard protocols of absorbed dose to water. The calibration factor ($N_{D.W.Q}$) of the ion chamber (TM30013, PTW, Germany) was determined using the EGSnrcCPP Monte Carlo Code. The calculated calibration factor ($N_{D.W.Q}$) was 5.28 cGy/nC. The calculated factor was then used to determine the absorbed dose to water from which the air kerma strength for an Ir-192 source can be easily derived at the reference point (5 cm). The calculated air kerma strength showed discrepancies of -0.6% to +1.8% relative to the air kerma strength provided by the vendor, In this work we demonstrated that the air kerma strength ($S_k$) could be determined from the absorbed dose to water calibration factor for Ir-192 source. In audition, this source calibration method could be applied directly to the dose Calculation formalism of AAPM report TG-43.

• Journal of Korea Far Infrared Association
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• s.24
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• pp.32-37
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• 2005

공기이온에 관한 연구는 많은 분야의 연구원 참여에 의해 폭넓게 알려져, 반세기에 이르는 번영의 역사를 쌓아 왔지만, 불가사의하게도 현재, 가장 중요한 적용분야인 보건 분야에서 위기를 맞고 있다. 20세기 초, 대기 중에 전하를 띤 입자의 존재가 관찰된 이래, 공기 이온의 성질을 문제로 한 기초적 연구가, 간단한 공기이온계측기 보급과 함께, 물리학자, 생물학자, 의학자의 협력 하에 1930년대 이후 활발히 이루어져, 공기이온의 위생적ㆍ치료적 가치에 대한 풍부한 정보를 얻을 수 있게 되었다. 어찌되었든 이온화환 공기 속에서는 생활할 수 없는 것이 확실해져, 어떤 농도의 공기이온은 사람 및 동물의 생체에 유익한 작용을 하고, 대용량 공기이온은 치료에 적용가능하지만, 농도의 여하에 관계없이, 양이온이 음이온에 비해 2~3배 우세하면, 신체의 상태를 악화시켜며, 또한 공조설비와 필터류는 모두 이온화작용을 나타내는 것도 밝혀졌다. 청정한 공기를 이온화하는 것은 산소, 탄산가스, 약용물질분자를 활성화시키지만, 오염된 공기의 이온화는 유독한 불순물의 독성을 증가시키는 점도 지적되었다.

• The Journal of Korean Academic Society of Nursing Education
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• v.17 no.3
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• pp.524-535
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• 2011

유전 위험 사정과 상담서비스가 임상실무에 널리 적용되어 감에 따라, 다양한 비용효율 면에서 다양한 상담서비스 모델을 사정하고, 대상자의 임상 요구와 건강문제를 해결하는데 어떤 모델이 유용한 지 확인할 필요가 있다. 본 연구의 목적은 114건의 현장 관찰과 문헌고찰을 통하여 3가지 유전상담 모형을 분석하였다. 유전의학 전문가 모델, 유전상담사 모델, 임상연구전문가 모델을 중심으로 각 모델의 구조, 전문가의 역할 및 기능, 목표, 물리적 세팅, 교육도구 등을 분석하였다. 각 모형 안에서 환자에게 기대되는 결과 면에서 질적 서비스가 보장되는지 확인하기 위하여 이론적 분석을 실시하였다. 본 연구를 통하여 각 모형의 상담 전, 중, 후 환자 만족, 지식 변화, 상담 효과 및 커뮤니케이션 효과 등을 분석하였지만, 결론적으로 상담서비스가 이루어지고 있는 기관의 구조를 충분히 고려하지 않은 상태에서 최상의 서비스 모델을 제시하기 어려울 것임을 논의하였다.

• Progress in Medical Physics
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• v.12 no.2
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• pp.103-112
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• 2001

Purpose: The purpose of this study was to investigate the current status of performing nuclear medicine quality control in korea and to test selected protocols of quality control of nuclear medicine counting system and gamma camera. Materials and Methods: Fifty three hospitals were included to investigate the current status of nuclear medicine quality control in korea. The precision of dose calibrator and thyroid uptake system was measured with Tc-99m 35.52 MBq for 2 minuets and Tc-99m 5.14 MBq for 10 sec every one minute, respectively. The sensitivity of CeraSPECT$^{TM}$ with low energy high resolution parallel hole collimator was measured using two cylindrical phantoms with 15 cm in diameter and 12 cm and 30 cm in heights containing Tc-99m. The correction factor for sensitivity of CeraSPECT$^{TM}$ was calculated using phantom data. The system planar sensitivity, uniformity, count rate and spatial resolution were measured for Varicam gamma camera with low energy high resolution parallel hole collimator using 140 keV centered 20% energy window, 256$\times$256 or 512$\times$512 matrix sizes. Results: The quality control of dose calibrator and well counter were showed poor performance status. On the other hand, The quality control of gamma camera and other systems were showed relatively good performance status. The results of precision of dose calibrator and thyroid uptake system was $\pm$1.4%(<$\pm$5%) and chi^2=29.7(>16.92), respectively. It showed that the sensitivity of CeraSPECT$^{TM}$ was higher in center slices compared with the edge slices. After correction of nonuniform sensitivities for patient data, it showed better results compare with prior to correction. System planar sensitivity of Varicam gamma camera was 4.39 CPM/MBq. The observed count rate at 20% loss was 102,407 counts/sec (head 1), 113,427 counts/sec (head 2), when input count rate was 81,926 counts/sec (head 1), 90,741 counts/sec (head 2). The spatial resolution without scatter medium were 8.16 mm of FWHM and 14.85 mm of FWTM. The spatial resolution with scatter medium were 8.87 mm of FWHM and 18.87 mm of FWTM. Conclusion: It is necessary to understand the importance of quality control and to perform quality control of nuclear medicine devices.vices.

• Progress in Medical Physics
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• v.22 no.4
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• pp.198-205
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• 2011

Gamma irradiator is widely used for cell, animal experiment, irradiation for blood, dose measurement, and education. Biobeam8000 gamma irradiator (STS Steuerungstechnik &. Strahlenschutz GmbH, Braunschweig, Germany, Cs137, 81.4 TBq) that KIRAMS (Korea Institute of Radiological and Medical Science) has is a irradiation device that enables to be used in large-capacity of 7.5 L and extensive area. Cs-137 source moves range of 24 cm back-and-forth in a regular cycle in beaker for uniform irradiation and a beaker that puts a specimen like existing radiation irradiator such as Gammacell3000 rotates $360^{\circ}$ during irradiation. Precise dose information according to the location of radiation source would be needed because of the movement of radiation source, whereas radiation could be uniformly irradiated in comparison with existing gamma irradiator. In this study, dose distribution of the inside beaker located in Biomeam8000 gamma irradiator was measured using glass dosimeter, and dose evaluation and distribution regarding dose linearity and dose reproducibility were implemented based on measurement results. This aims to show guideline for efficient use of irradiator based on measurement result when doing experiment or radiation exposure.

• Progress in Medical Physics
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• v.5 no.2
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• pp.13-20
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• 1994

The thermoluminescence(TL) glow curves and the optical absorption of $Al_2O_3$ irradiated with ${\gamma}$-ray, electron, and $Li^{+}$ ion followed by electron irradiation have been investigated to determine the relation of TL peak to its defect type. The TL glow curve of $Al_2O_3$ irradiated with ${\gamma}$-ray shows TL peaks at 380 K, 415 K, and 475 K. The UV photobleached TL glow curve of $Al_2O_3$ irradiated with ${\gamma}$-ray shows that the 380 K and 475 K TL peaks completely disappear while the 415 K TL peak still exists. The electron beam induced TL glow curve of $Al_2O_3$ after $Li^{+}$ ion implantation shows that the TL peak at 440 K is enhanced by a factor of 2 over the TL intensity of unimplanted $Al_2O_3$ while the TL peak at 380 K evidently disappears The implanted $Li^{+}$ ions are assumed to form singly charged interstitial cations and then recombine with electron trapped in F centers to produce F+ centers. The 380 K and 475 K TL peaks are proposed to be associated with F center, while the 415 K and 440 K TL peak are connected with F$^{+}$ center.

• Progress in Medical Physics
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• v.27 no.1
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• pp.46-53
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• 2016

Periodical calibrations of radiation detectors are important for accurate quality assurance of therapeutic linac. The measuring instruments such as ion-chamber, thermometer, barometer, and survey meter should be calibrated periodically. Period of calibration for these instruments is suggested 6 month to one year in Korea and two years in other countries nowadays. Therefore, the determination of reasonable period for calibration is needed. In this study, we plan to utilize the results of these survey; frequent in use, how to use and stability of instruments, to determine the optimized period of calibration for the instruments in the departments of radiation oncology in Korea based on the ILAC-G24. The SurveyMonkey web-based survey tool was used and the objects of survey were 18 department of radiation oncology in university hospitals, and 15 departments were answered. The 64 questionnaires which supposed to be answered in 50 minutes were classified as the information of candidates, the thermometer, the barometer, the surveymeter, and the ion-chamber. The thermometers and the barometers were not under periodical calibration for more than half of candidates. The periods of calibration of surveymeters were 6 month to 1 year. We expect that the calibration period can be determined based on these survey results.