• Title/Summary/Keyword: 의료영상분석

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Quantitative and cell count analysis of Breat cancer cell nuclei by Immunohisto-chemical stained tissue section (면역조직화학염색에 의한 유방암 세포핵의 정량적 분석과 세포수에 의한 분석)

  • 허민권;최흥국;서정욱
    • Proceedings of the Korea Multimedia Society Conference
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    • 1998.10a
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    • pp.243-247
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    • 1998
  • 전자현미경 영상인 유방암 조직세포의 암 분포 정도를 알기 위해, 조직세포중 암이 퍼진 부분과 그렇지 않은 부분에 대해 정량적 분석과 세포수에 의한 분석을 비교하여 보았다. 유방암 조직세포의 면역조직화함염색에서 암이 있는 세포핵은 갈색으로 나타났고, 그렇지 않은 세포는 푸른색으로 나타났다. 이것은 환자를 진단하고 예지하는데 있어서 중요한 요인으로 작용하지만 지금까지는 의사의 주관적인 생각이 다분히 포함된 판단에 의존할 수 밖에 없었다. 의료영상이미지의 시각적 표현을 위해 RGB칼라를 HLS칼라로 변환하여 사용하였으며, 이것은 시각적으로 좀 더 쉽게 갈색세포핵과 푸픈색 세포핵을 구분하게 해 주었다. 두 세포핵을 분리하기 위해 히스트그램의 임계치와 Box classification의 두 알고리즘의 사용하여 추출하였다. 그리고 추출한 세포핵들에 대해 각각 정량적인 분석과 세포수에 의한 분석을 하였다. 이러한 실험은 시각적 병리정밀검사에 좋은 보조도구로 사용될 수 있을 것이다.

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The Cerebro-region Extraction Using Cellular Automata (셀룰러 오토마타를 이용한 뇌 영역 추출에 관한 연구)

  • 이승용;허창우;류광렬
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.7
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    • pp.1551-1555
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    • 2003
  • This paper describes the extraction method for cerebro-region using cellular automata from the cerebrum MR images. The cerebro-region extracted from applying the cellular automata rules obtained from histogram distribution analysis after removing the background image from the cerebro-region by determining the critical value. The experiment results showed that PSNR is 42㏈ on the image quality and the correlation factor is estimated 98%. And the result can be used as the medical auto-diagnostics system of cerebrum.

Simulation Study for Feature Identification of Dynamic Medical Image Reconstruction Technique Based on Singular Value Decomposition (특이값분해 기반 동적의료영상 재구성기법의 특징 파악을 위한 시뮬레이션 연구)

  • Kim, Do-Hui;Jung, YoungJin
    • Journal of radiological science and technology
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    • v.42 no.2
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    • pp.119-130
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    • 2019
  • Positron emission tomography (PET) is widely used imaging modality for effective and accurate functional testing and medical diagnosis using radioactive isotopes. However, PET has difficulties in acquiring images with high image quality due to constraints such as the amount of radioactive isotopes injected into the patient, the detection time, the characteristics of the detector, and the patient's motion. In order to overcome this problem, we have succeeded to improve the image quality by using the dynamic image reconstruction method based on singular value decomposition. However, there is still some question about the characteristics of the proposed technique. In this study, the characteristics of reconstruction method based on singular value decomposition was estimated over computational simulation. As a result, we confirmed that the singular value decomposition based reconstruction technique distinguishes the images well when the signal - to - noise ratio of the input image is more than 20 decibels and the feature vector angle is more than 60 degrees. In addition, the proposed methode to estimate the characteristics of reconstruction technique can be applied to other spatio-temporal feature based dynamic image reconstruction techniques. The deduced conclusion of this study can be useful guideline to apply medical image into SVD based dynamic image reconstruction technique to improve the accuracy of medical diagnosis.

Pulsimeter Design by analyzing a moving pulse image (맥동 영상 분석에 의한 맥진기 설계)

  • Lee, woo-beom;Choi, chang-yur;Hong, you-sik;Lee, sang-suk;Nam, dong-hyun
    • Proceedings of the Korea Contents Association Conference
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    • 2011.05a
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    • pp.13-14
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    • 2011
  • 심혈관계 질환의 발병 위험요인 분석이 가능한 맥진기는 한방 의료기기에서 대표적인 연구 분야 가운데 하나이다. 그러나 기존의 대부분의 센서 기반의 맥진기는 측정시의 맥박 박동처와 센서부의 접촉상태에 따른 편위, 검출된 파형의 부정확성 및 파형분석의 어려움 등에 있어서 문제점이 발생한다. 따라서 본 논문에서는 맥동에 의해서 유발되는 모세관 시험액의 상태 변화를 촬영한 맥동 영상을 분석하여 환자의 맥파의 측정이 가능한 맥진기를 제안한다. 제안한 맥진기의 성능 평가를 위해서는 추출된 맥파로부터 맥파 분석에 필수적인 5가지 특징점에 대한 추출률을 측정한 결과 성공적인 결과를 보였다.

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Simulation and Experimental Studies of Super Resolution Convolutional Neural Network Algorithm in Ultrasound Image (초음파 영상에서의 초고분해능 합성곱 신경망 알고리즘의 시뮬레이션 및 실험 연구)

  • Youngjin Lee
    • Journal of the Korean Society of Radiology
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    • v.17 no.5
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    • pp.693-699
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    • 2023
  • Ultrasound is widely used in the medical field for non-destructive and non-invasive disease diagnosis. In order to improve the disease diagnosis accuracy of diagnostic medical images, improving spatial resolution is a very important factor. In this study, we aim to model the super resolution convolutional neural network (SRCNN) algorithm in ultrasound images and analyze its applicability in the medical diagnostic field. The study was conducted as an experimental study using Field II simulation and open source clinical liver hemangioma ultrasound imaging. The proposed SRCNN algorithm was modeled so that end-to-end learning can be applied from low resolution (LR) to high resolution. As a result of the simulation, we confirmed that the full width at half maximum in the phantom image using a Field II program was improved by 41.01% compared to LR when SRCNN was used. In addition, the peak to signal to noise ratio (PSNR) and structural similarity index (SSIM) evaluation results showed that SRCNN had the excellent value in both simulated and real liver hemangioma ultrasound images. In conclusion, the applicability of SRCNN to ultrasound images has been proven, and we expected that proposed algorithm can be used in various diagnostic medical fields.

Clustered Microcysts Detected on Breast US in Asymptomatic Women (무증상 여성의 유방초음파에서 발견된 군집 미세낭종)

  • Hyun Jin Kim;Jin Hwa Lee;Young Mi Park;Kyungjae Lim
    • Journal of the Korean Society of Radiology
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    • v.84 no.3
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    • pp.676-685
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    • 2023
  • Purpose To investigate the incidence, outcomes, and imaging characteristics of clustered microcysts detected on breast US in asymptomatic women, and suggest appropriate management guidelines. Materials and Methods We identified and reviewed the lesions recorded as "clustered microcysts" on breast US performed in asymptomatic women between August 2014 and December 2019. The final diagnosis was based on pathology and imaging follow-up results for at least 12 months. Results The incidence was 1.5% and 100 patients with 117 lesions were included. Among 117 lesions, 3 (2.6%), 2 (1.7%), and 112 (95.7%) were malignant, high-risk benign, and benign lesions, respectively. The malignant lesions included two cases of ductal carcinoma in situ and one invasive ductal carcinoma. Two of them were assessed as category 4, showing mammographic suspicious microcalcifications and internal vascularity on Doppler US. The remainder was a false negative case and showed echo pattern change on the 12-month follow-up US. Conclusion The incidence of clustered microcysts on breast US in asymptomatic women was 1.5% and malignancy rate was 2.6% (3 of 117). Knowledge of outcomes and imaging features of benign and malignant clustered microcysts may be helpful for radiologists, thereby aiding categorization and management recommendations.

A Study on a Mask R-CNN-Based Diagnostic System Measuring DDH Angles on Ultrasound Scans (다중 트레이닝 기법을 이용한 MASK R-CNN의 초음파 DDH 각도 측정 진단 시스템 연구)

  • Hwang, Seok-Min;Lee, Si-Wook;Lee, Jong-Ha
    • Journal of the Institute of Convergence Signal Processing
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    • v.21 no.4
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    • pp.183-194
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    • 2020
  • Recently, the number of hip dysplasia (DDH) that occurs during infant and child growth has been increasing. DDH should be detected and treated as early as possible because it hinders infant growth and causes many other side effects In this study, two modelling techniques were used for multiple training techniques. Based on the results after the first transformation, the training was designed to be possible even with a small amount of data. The vertical flip, rotation, width and height shift functions were used to improve the efficiency of the model. Adam optimization was applied for parameter learning with the learning parameter initially set at 2.0 x 10e-4. Training was stopped when the validation loss was at the minimum. respectively A novel image overlay system using 3D laser scanner and a non-rigid registration method is implemented and its accuracy is evaluated. By using the proposed system, we successfully related the preoperative images with an open organ in the operating room

Automatic Disk Disease Recognition based on Feature Vector in T-L Spine Magnetic Resonance Image (척추 자기 공명 영상에서 특징 벡터에 기반 한 디스크 질환의 자동 인식)

  • 홍재성;이성기
    • Journal of Biomedical Engineering Research
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    • v.19 no.3
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    • pp.233-242
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    • 1998
  • In anatomical aspects, magnetic resonance image offers more accurate information than other medical images such as X ray ultrasonic and CT images. This paper introduces a method that recognizes disk diseases from spine MR images. In this method, image enhancement, image segmentation and feature extraction for sagittal plane and axial plane images are performed to separate the disk region. And then template matching method is used to extract disease region for axial plane imges. Finally, disease feature vectors are integrated and disease discrimination processes are performed. Experimental results show that the proposed method discriminates between normal and diseased disk with a considerable recognition ratio.

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Evaluation of the usefulness of prone position for reducing the image distortion due to respiration in PET/CT (PET/CT 검사 시 호흡에 따른 영상 왜곡 감소를 위한 엎드린 자세의 유용성 평가)

  • Lee, Han Wool;Kim, Jung Yul;Choi, Yong Hoon;Lim, Han Sang;Kim, Jae Sam
    • The Korean Journal of Nuclear Medicine Technology
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    • v.23 no.1
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    • pp.59-63
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    • 2019
  • Purpose The motion due to respiration of patients undergoing PET/CT is a cause of artifacts in image and registration error between PET and CT images. The degree of displacement and distortion for tumor, which affects the measurement of Standard Uptake Value (SUV) and lesion volume, is especially higher for tumors that is small or located at the base of lungs. The purpose of this study was to evaluate the usefulness of prone position in the correction of image distortion due to respiration of patients in PET/CT. Materials and Methods The imaging equipment used in this study was PET/CT Discovery 600 (GE Healthcare, MI, USA). 20 patients whose lesions were identified in the middle and lower lungs from May to August 2018 were enrolled in this study. After acquiring whole body image in the supine position, additional images of the lesion area were obtained in the prone position with the same conditions. SUVmax, SUVmean, and volume of the lesion were measured for each image, and the displacement of the lesion on PET and CT images were measured, compared, and analyzed. Results The SUVmax, SUVmean, and volume, and displacement of the lesion were $4.72{\pm}2.04$, $3.10{\pm}1.38$, $4.68{\pm}3.20$, and $4.64{\pm}1.88$, respectively for image acquired in the supine position and $5.89{\pm}2.42$, $3.97{\pm}1.65$, $2.13{\pm}1.09$, and $2.24{\pm}0.84$, respectively for image acquired in the prone position, indicating that, for all the lesions imaged, SUVmax and SUVmean were higher and volume and displacement were smaller in the images acquired in prone position compared to those acquired in supine one(p<0.05). Conclusion These results showed that the prone position PET/CT imaging improves the quality of the image by increasing the SUV of the lesion and reducing the respiratory artifacts caused by registration error between PET and CT images. It is considered that the PET/CT imaging in the prone position is helpful in the diagnosis of the disease as an economical and efficient methods that correct registration error for the lesions in basal lung and reduce artifacts.

The diffusion and policy options of the diagnostic imaging technologies in Korea (의사결정나무 분석을 사용한 고가의료장비의 다빈도 사용 특성 분석)

  • Choi, Yoon Jung;Kwak, Minjung;Yoon, Min
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.1
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    • pp.179-185
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    • 2015
  • The cost of advanced medical technologies is commonly considered to be a major factor in the overall escalation of expenditures on health. The use of computed tomography (CT) scanning has increased dramatically over the past decade. CT has been rapidly adopted, despite their high cost. The aim of this study is to analysis the increasing factor of the frequency of the CT, using the decision tree model. Finally, we propose the effective policy option of diagnostic imaging technology in Korea.