• 대한의용생체공학회:의공학회지
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• 제43권6호
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• pp.417-423
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• 2022

The present study proposed a new interface system for capsule endoscopy by using head mounted display (HMD) device, which can control the orientation of the capsule endoscope with electromagnetic actuator (EMA) system. The orientation information of the HMD user was detected by the gyroscope sensor built into the device and then calculated to as an angle increment using Unity Engine compiler. The measured angle changes from the HMD were converted to the current values of the corresponding coils to be changed in the EMA system. Two experiments were designed to measure the accuracy and the intuitiveness of the HMD interface system. In the angle accuracy measurement, the capsule endoscope driven by HMD interface system showed the averaged errors of 0.68 degrees horizontally and 1.001 degrees vertically for given test angles. In the intuitiveness measurement, HMD interface system showed 1.33 times faster manipulation speed rather than the joystick interface system. In this respect, the HMD interface system for capsule endoscopy was expected to improve the overall diagnostic environment while maintaining comfort of patients and clinicians.

• 대한의용생체공학회:의공학회지
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• 제44권4호
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• pp.264-274
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• 2023

Purpose: The objective is to extract insights that can contribute to the formulation of harmonized international policies and support measures for innovative medical devices and management systems. This study aims to propose effective strategies for future medical device innovation and healthcare delivery. Results: It investigates technological advancements, regulatory approval systems, insurance policies, and successful commercialization cases in South Korea, the United States, and the European Union. In 2018, the FDA implemented insurance coverage for Software as a Medical Device (SaMD) and recognized insurance coverage for Digital Therapeutics (DTx). Germany is a country that ensures permanent reimbursement for healthcare applications since 2020, making it the first country to provide legal health insurance coverage for fostering a digital ecosystem. Conclusion: The findings of this research highlight the importance of cultivating a supportive regulatory and environmental framework to facilitate the adoption of innovative medical devices. Continuous support for research and development (R&D) efforts by companies, along with the validation of clinical effectiveness, is crucial.

• 대한의용생체공학회:의공학회지
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• 제15권1호
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• pp.1-8
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• 1994

Electrofusion of cabbage protoplasts was performed with a developed equipment which consists of a parallel wire electrode, a AC field generator, and a pulse generator. Exposure of protoplasts to an alternating current field of 450 KHz causes attraction to each other which leads to chains of protoplasts extending from the electrode. Intra-specific protoplast fusion was effectively induced within the pearl chains by the additional application of a single high-intensity DC square wave pulse of 1 KV/cm for 1-3 msec. To improve the performance, micro fusion electrode fabricated from the semiconductor technology and microcontroller based field an, d pulse generator was proposed. The viability of protoplasts after an application of electric field at optimum condition was reduced by only 5 % compared with that of pre-application. A prototype of fusion electrode, which consists of insulator-structure, was successfully fabricated by using photosensitive polyimide.

• 대한의용생체공학회:의공학회지
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• 제17권2호
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• pp.173-178
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• 1996

The objective of this paper is to investigate the effect of AC field on the protoplast of plant cells. The results of investigation will be the basis for the development of etectric cell fusion device. For the experiment, we made the electrode and AC and DC pulse generator and observed the behavior of the protoplasts through the inverted microscope which is connected to the monitor and video recorder by the CCD camera. As a result, the numbers of rotating, moving and destructed protoplasts and viability of the protoplasts have close relation to the amplitude of AC field, while the rotation rate is closely related to the frequency of AC pulse.

• 한국수산과학회지
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• 제55권5호
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• pp.638-644
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• 2022

The measurement of morphological features is essential in aquaculture, fish industry and the management of fishery resources. The measurement of fish requires a large investment of manpower and time. To save time and labor for fish measurement, automated and reliable measurement methods have been developed. Automation was achieved by applying computer vision and machine learning techniques. Recently, machine learning methods based on deep learning have been used for most automatic fish measurement studies. Here, we review the current status of automatic fish measurement with traditional computer vision methods and deep learning-based methods.

• 접착 및 계면
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• 제24권4호
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• pp.113-119
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• 2023

홍합의 수중 접착능력은 도파(DOPA)와 라이신(Lysine), 히스티딘(Histidine)과 같은 홍합접착단백질의 아미노산 잔기가 중요한 역할을 한다고 보고되었고, 이에 따라, 카테콜과 아민기를 동시에 갖는 접착성 카테콜아민(Catecholamine) 물질을 기반으로 다양한 의공학적 연구가 진행되고 있다. 카테콜기가 도입된 키토산은 아민이 풍부한 키토산에 카테콜기를 도입한 카테콜아민으로, 이를 이용하여 조직접착제나 창상치유제, 지혈제, 약물전달체 및 조직공학용 담체 등 다양한 의공학적 적용이 가능하다. 특히, 키토산-카테콜 물질은 지혈제로 미국 및 한국 식품의약품안전처의 승인을 받아, 연구개발에서부터 제품개발까지 이루어진 홍합 모사 물질이다. 이에 본 총설에서는 지혈제로써의 키토산-카테콜 물질에 대한 연구 동향을 살펴보고자 한다. 이를 위해, 카테콜기가 도입됨에 따라 나타나는 키토산-카테콜의 특성, 지혈 메커니즘, 다양한 제형에 대하여 다루고자 한다.

• 문화기술의 융합
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• 제10권2호
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• pp.35-42
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• 2024

의공학은 의학 및 생물학적 이해를 바탕으로 공학적 기술을 이용하여 인체 질병을 진단하고 치료하는 학문이다. 올바른 의공학 교육을 위해서는 교육과정에 의학용어, 인체해부학, 인체 생리학 등의 교육이 필요하지만 학생들은 이들 의학 기초 과목들을 암기 과목이라는 선입견을 가지고 있다. 이러한 학생들의 선입견을 해소시키기 위해서는 다양한 교육방법을 개발하여 학생들이 기초의학 과목들에 쉽게 접근할 수 있도록 해야 한다. 본 논문에서는 의학용어 과목에 인체 반신 해부 모형의 관찰 실습을 도입하여 학습 효과를 높이는 방법을 제시한다. 인체 반신 모형은 여러가지 장기가 조립되어 있는 형태이며 하나씩 분해하면서 관찰할 수 있다. 본 관찰 실습은 머리, 목, 가슴, 복부 부위의 장기들에 대한 질문으로 구성하여 학생들이 조별로 답을 찾아가도록 구성하였다. 학생들은 실습 후 이 실습이 학습동기를 유발하고 강의의 이해를 쉽게 해 주었다고 평가하였다.

• 한국융합학회논문지
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• 제12권7호
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• pp.263-271
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• 2021

거총부터 격발까지 총구 움직임의 궤적을 추적하여, 사격의 정확성을 향상시킬 목적으로 광전자 기반 사격 훈련 시스템이 사격 훈련 현장에서 활용되어 왔다. 광전자 기반 시스템은 설치가 복잡하고, 표적의 파손 위험이 존재하며, 고가의 장비로 선수들의 접근성이 떨어진다는 단점이 있다. 이에 본 연구는 저비용의 가속도 센서 모듈을 이용하여 체위 떨림을 측정하고 피드백할 수 있는 사격 훈련 시스템을 개발하고, 이의 활용성을 검증하였다. 가속도 센서 모듈은 총기의 에어 실린더에 부착할 수 있도록 제작되었다. 체위 떨림은 가속도 센서 데이터를 이용하여 진폭, 주파수, 공간적 패턴 지표로서 분석되었다. 가속도 센서와 기존의 광전자 기반 시스템에서 측정된 사격시 체위 떨림 진폭 지표 간에는 높은 상관관계(좌우 방향: r=0.76; 상하 방향: r=0.70)가 나타났다. 또한, 사격 선수를 대상으로 진행한 시스템의 유효성 평가에서는 선수의 사격 점수(최상, 최하 격발)에 따라 계산된 체위 떨림 지표가 유의한 차이(p<0.05)가 있음을 독립 표본 t-검증을 이용하여 검증하였다.

• 대한의용생체공학회:의공학회지
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• 제41권6호
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• pp.256-263
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• 2020

The importance of quality control has been emphasized to maintain safety of patients and satisfaction of medical service with medical devices used in clinic. Accordingly, objective evaluation method and standards consistently has been brought up for demand to replace outdated medical devices in appropriate time and to maintain the quality of medical service. Though many studies made suggestions methods to determine what medical devices to be replaced first, these methods were difficult in practice for its complex evaluation criteria and long time to evaluate. Therefore, in this study, a simple evaluation method is developed to identify and prioritize medical devices that are ought to be replaced. For the development of this simple evaluation method, four major characteristics of technology, safety, finance, and user satisfaction, which are considered in clinics to evaluate medical device replacement, and 14 minor attributes are distinctively selected. Each characteristic is assessed in binary form of "YES" or "NO" to minimize its subjective nature. Using this method to evaluate sampled medical devices belonging to four different characteristics, devices are suggested to be replaced in the current financial year or in the following financial year, or re-evaluated by the end of this financial year. Such results of evaluation can amend the subjective nature of existing evaluation method and give objective standards more promptly.

• 대한의용생체공학회:의공학회지
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• 제43권1호
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• pp.61-70
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• 2022

Natural and synthetic forms of calcium phosphate cement (CPC) have been widely used in bone repair and augmentation. The major challenge of injectable CPC is to deliver the cells without cell death in order to regenerate new bone. The study objective was to investigate for the potential of stem cell-laden gelatin fibers containing injectable, nanocrystalline CPC to function as a delivery system. Gelatin noddle fiber method was developed to delivered cells into nCPC. Experimental groups were prepared by mixing cells with nCPC, mixing cell-laden gelatin fibers with nCPC and mixing cell-laden gelatin fibers containing BMP-2 with nCPC. Media diffusion test was conducted after dissolving the gelatin fibers. SEM examined the generated channels and delivered cell morphology. Fibers mixed with nCPC showed physical setting and hardening within 20 min after injection and showed good shape maintenances. The gelatin fibers mixed nCPC group had several vacant channels generated from the dissolved gelatin. Particularly, proliferation and attachment of the cells were observed inside of the channels. While live cells were not observed in the cell mixed nCPC group, cells delivered with the gelatin fibers into the nCPC showed good viability and increased DNA content with culture. Cell-laden gelatin fiber was a novel method for cell delivery into nCPC without cell damages. Results also indicated the osteogenic differentiation of gelatin fiber delivered cells. We suggest that the cell-laden gelatin fibers mixed with nCPC can be used as an injectable cell delivery vehicle and the addition of BMP-2 to enhances osteogenesis.