• Korean Journal of Clinical Laboratory Science
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• v.53 no.3
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• pp.249-256
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• 2021

Asthma is a chronic inflammatory airway disease. There are many factors including genetic and environmental factors that influence asthma. The mitogen-activated protein kinase (MAPK) pathway is involved in maintaining the T helper cells 1 and 2 (Th1/Th2) balance and plays an important role in the development of asthma. In this study, the correlation between the NDFIP2 gene that regulates the MAPK pathway and asthma was analyzed. The genetic polymorphism of the NDFIP2 gene was analyzed between 193 asthma patients and 3,228 healthy controls in Korea. As a result, 4 single nucleotide polymorphisms (SNPs) showed a significant correlation (P<0.05) and high relative risk with asthma. Among them, rs2783122 of NDFIP2 showed a statistically significant association with asthma (P-value=9.76×10^-6, odds ratio (OR)=1.67, 95% confidence interval (CI)=1.33~2.10). In the SNP imputation on the NDFIP2, 16 SNPs were discovered, and all of them showed significant correlation with asthma and high odds ratio. The genotype-based mRNA expression analysis revealed that the group of minor alleles of rs1408049 showed increased mRNA expression. Increased NDFIP2 expression causes the activation of the MAPK pathway, and this may influence the development of asthma. In conclusion, the polymorphisms of NDFIP2 are associated with asthma development and this can provide the basis for new guidelines for the management of asthma in the Korean population.

• Journal of Digital Convergence
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• v.19 no.5
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• pp.249-262
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• 2021

It is believed that there will be changes in the behavior of members according to the characteristics of the organization's leader. The purpose of this study is to find out the factors that induce changes in the behavior of employees of the organization through empirical research. In order to accomplish the research aims, we developed and verify the research model using authentic leadership as an independent variable and the innovative behavior as a criterion variable. In addition, by using the silent phenomenon of the members as a mediating variable, we also tried to find out how it affects the behavior of the employees. Empirical results of the study showed that authentic leadership as an independent variable had a direct influence on the innovation behavior of employees, and the mediating effect of silence also had a partial mediating effect. These findings suggest that leadership and Silence factors which are internal motivational factors leading to behavior of employees are affected innovative behavior. There are some expectations as follow. Based on this study, it would be an important issue that the study on the necessity of silence management of employees through research on the causes of silence felt by members of the organization and the influence.

• Journal of the Korean Chemical Society
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• v.65 no.5
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• pp.333-346
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• 2021

In this study, we developed education materials using history of science related to the experiment of 'Boyle's air pump' and the Boyle and Hobbs' debate of vacuum to find out the perceptions of NOS by pre-service chemistry teachers. For the study, 29 pre-service chemistry teachers at a college of education in Chungcheongbuk-do were selected. As RFN items that were related to the contextual situation developed in this study, items in the categories of 'Aims and Values', 'Scientific practices', 'Scientific Methods among Educational Applications' and 'Social-Institutional Aspects among Educational Applications' were selected. Through the items of RFN, the perceptions of pre-service teachers in non-contextual situations were investigated. Then we presented the pre-service teachers with the situation related to Boyle's experiment on air pump and Boyle and Hobbes' debate over vacuum. In addition, their perception of NOS was examined in contextual situations related to RFN items. Responses to the items, experimental results related to Boyle's Law, group discussion, and interview data were collected as data. As a result of the study, it was found that pre-service teachers had informed perceptions in most of the items, but cases with naive views or mixed views were found in context experimental situations. This study can contribute to the NOS education for pre-service chemistry teachers by development of context situation education materials related to NOS and by finding out their perceptions in the non-contextual and contextual situation.

• Journal of radiological science and technology
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• v.44 no.5
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• pp.503-512
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• 2021

The purpose of this study is to check the extent to which "instruction of physician or dentist" defined in the Medical Service Technologists, etc. Act is applied in relation to radiography examination procedures for radiological technologists. In addition, it is intended to present basic data on the requirement to revise the Medical Service Technologists, etc. Act in the radiological technologist's duty area and scope of work, The subjects of this study were radiological technologists with license, and the response data were collected after sending the questionnaire link written on the online questionnaire form. The final number of respondents were 1,018, and the response rate was 6.8%. Most of the negative responses were "I have never received 'instruction' for radiologic examination by a physician or dentist, including a radiologist in a medical environment." There were a high perception that "the professionalism in radiation examination on radiological technologists are higher than that of a physician or dentist." They answered that the current continuing education has a great impact on maintaining and continuing professionalism and learning new knowledge in the radiology field. In addition, the radiological technologists provide a very high level of education in areas related to radiography procedure ethics such as patient care, patient safety, and patient privacy protection, as well as specialized fields such as radiation-related examination methods, radiography examination dose, and patient exposure dose. Radiological technologists replied that they were receiving it consistently. In conclusion, in the current medical environment, the 'instruction' of a physician or dentist cannot be seen as being realistically performed. The phrase 'instruction' of a physician or dentist as defined in the Medical Service Technologists, etc. Act is considered inappropriate in respect of the fact that the state recognizes the qualifications of the medical service technologist through a license. It is thought that revision to a new term suitable for the current medical environment is necessary.

• Korean Journal of Food Science and Technology
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• v.53 no.1
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• pp.104-110
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• 2021

In this study, vinegar was prepared using black raspberry pomace to increase its utilization capacity. As a result of alcohol fermentation, the final alcohol content was 8.90% and the sugar content was 7.03°Brix. The total acid content after acetic acid fermentation was 4.44%, which was 0.38% higher than that of the juice. Among the organic acid content, the acetic acid content was higher in the pomace than in the juice. The total polyphenol (51.58 TAE mg/mL), total flavonoid (9.55 RUE mg/mL), and total anthocyanin (6.05 CYE mg/mL) contents of vinegar produced using black raspberry residue were higher than those of the juice. In addition, 2,2'-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity, reducing power, and ferric reducing antioxidant power (FRAP) activity were higher than those of the juice, indicating strong antioxidant properties. Thus, black raspberry pomace has excellent acetic acid fermentation ability and high antioxidant activity, indicating that it can be used as a functional fermented vinegar.

• Tunnel and Underground Space
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• v.31 no.1
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• pp.52-65
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• 2021

In this study, authors analyzed the vapor cloud explosion induced by propane leak at the PEMIX Terminal, which is the propane storage facility outside of Mexico City. TNT equivalence mass for the leaked 4750 kg propane was estimated to be 9398 kg. Blast parameters such as peak overpressure, positive phase duration, and impact at 40-400 (m) away from the center of the explosion were calculated by applying TNT Equivalency Method and Multi-Energy Method. The probability of damage due to lung damage, eardrum rupture, head impact, and whole-body displacement impact by applying the probit function obtained using blast parameters was evaluated. The peak overpressure obtained using Multi-Energy Method was found to be greater than the peak overpressure obtained by applying the TNT Equivalency Method at all distances considered, but it was evaluated that there was no significant difference from the points above 200 m. The peak overpressure obtained by Multi-Energy Method was computed to assess the extent of damage to the structure, and it was shown that structures within 100 m of the explosion center would collapse completely, and that the glasses of the structures 400 m away would be almost broken. The probability of death due to lung damage was shown to vary depending on a human body's position located in the propagating direction of shock wave, and if there is a reflecting surface in the immediate surroundings of a human body, the probability of death was estimated to be the greatest. The impact of shock wave on lung damage, eardrum rupture, head impact, and whole-body displacement impact was evaluated and found to affect whole-body impact < lung damage < eardrum rupture

• The Journal of the Korea Contents Association
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• v.20 no.12
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• pp.383-392
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• 2020

This study was conducted to understand the current status associated with challenging behaviors of adults with developmental disabilities and review the perception of workers at lifelong education centers for the developmentally disabled. To that end, a survey and a focus group interview were conducted. The findings were as follows. First, 85.4% of people working at lifelong education centers for the developmentally disabled had experienced injury in the past year due to challenging behaviors, and those who experience injuries responded that they suffered burnout, psychological trauma, and considered changing jobs. Second, in terms of preemptive response by the organization to address challenging behaviors, 'securing individual space' and 'preemptive identification of causes of challenging behaviors' ranked the highest, with 87.5% of the respondents giving this answer, respectively. For follow-up measures, 81.3% of organizations answered that they hold meetings on individual cases and provide supervision. Third, in terms of suggestions for ways to address challenging behaviors, establishment of an organization-wide system and cooperation with related organizations were cited as needed.

• Journal of Korea Society of Waste Management
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• v.35 no.8
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• pp.744-753
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• 2018

The Stockholm Convention, which was adopted in Sweden in 2001 to protect human health and the environment, includes regulations for Persistent Organic Pollutant Rotors such as toxic and bioaccumulatives. Currently, there are 28 types of materials. This prohibits and limits the production, use, and manufacture of products. Korea is a member of the Convention, and it is necessary to prepare management and treatment plans to address the POP trends. Thus, we experimentally investigate whether the environmentally stable incineration is achieved when the sample is thermally treated using the Lab-scale (1 kg/hr). The target samples is pesticides in liquid phase and solid phase. In this study, organic chlorinated pesticides and their thermal characteristics were analyzed. We calculated the theoretical air volume based on the element analysis results. Because the interior of the reactor is small, more than 10 times of the air ratio was injected. The retention time was set to at least 4 seconds using a margin. The incineration temperature was $850^{\circ}C$ and $1100^{\circ}C$. Thus, we experimentally investigated whether the environmentally stable incineration was achieved when the sample was thermally treated using the Lab-scale (1 kg/hr). We analyzed five types of exhaust gas; the 02 concentration was high, but the CO amount decreased. Complete combustion is difficult because of the small size of the furnace due to the nature of Lab-scale. The organic chlorine-containing pesticide had an average decomposition rate of 99.9935%. Considering the decomposition rates of organic chlorine-containing pesticide in this study, the incineration treatment at over 2 ton/hour, which is typical for a conventional incinerator, is possible. Considering the occurrence of dioxins and unintentional persistent organic pollutants, it can operate at more than $1,100^{\circ}C$.

• 교육공학연구
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• v.33 no.1
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• pp.105-135
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• 2017

The purpose of this study is to clarify conceptually the difference of instructional coaching, instructional supervision, and instructional consulting by analyzing their own characteristics. The practices for instructional improvement are common in that fundamental objectives are improvement of instruction and development of teacher's professionalism in instruction. However, each area changed according to the social flow and the demands of the educational field and created a unique activity system. So, in order to get rid of this mixed use of these terms, it is meaningful to distinguish the concepts, attributes, and areas of each activity. The specific study questions were 1) what is the origin of coaching, supervision, and consulting? 2) how are instructional coaching, instructional supervision, and instructional consulting defined in existing research in korea? 3) how can we conceptually distinguish instructional coaching, instructional supervision, and instructional consulting? Based on reviewing various existing studies, First, this study investigated the conceptual origins and lexicons of coaching, supervision, and consulting, respectively, in addition reviewd the prior studies conducted in Korea with regard to instructional coaching, instructional supervision, and instructional consulting, and summarized how each concept is defined according to the researcher. Second, this study compared each two concept with another one. Finally, the existing definitions of instructional coaching, instructional supervision, and instructional consulting were analyzed to find out the inherent and common attributes of each concept. In conclusion, this study suggest that the concept of instructional consulting needs to be redefined to better reflect the characteristics of activities, and that studies that rethink the relationship between instructional coaching and instructional supervision are needed.

• Korean Journal of Environmental Biology
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• v.39 no.1
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• pp.1-5
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• 2021

Radish is one of the major vegetable crops and has been damaged economically by the causal agent of Fusarium wilt disease, Fusarium oxysporum f. sp. raphani (FO) in the highlands of Gangwon province, Korea. Recently, clover cyst nematode, Heterodera trifolii(HT), occurred in highland of Jeongseon area and poses a threat to radish plants. The nematodes, besides causing direct damage to radish plants, possess the capability to synergize with other plant pathogens, leading to the development of a disease complex. The aim of this study was to investigate the interaction between FO and HT in radish plants. The length of plants co-infected with both FO and HT was shorter than that of plants infected with FO alone, but there was no statistically significant difference. However, the disease severity was much higher in the plants co-infected with both FO and HT(1.60±0.97) compared to FO alone(0.20±0.42)(df=3, F=10.17, p<0.001). Disease incidence was also about two-fold higher in plants co-infected with both FO and HT (80%) compared to FO alone (44%). These results suggested that the clover cyst nematode should be considered in the management of Fusarium wilt disease in the highlands of Gangwon province.