• Journal of Life Science
• /
• v.20 no.5
• /
• pp.717-722
• /
• 2010

The safety of animal feed was evaluated by analyzing the levels of heavy metals (Pb, Cr, Cd, As, Se and Ag) in cattle, swine, and poultry feeds and the levels of Cu, Zn and P in swine feed. Feeds used in the analysis were produced in Korea from 2004 through the first half of 2007. The results of the study revealed that, with the exception of Cd, the concentration of heavy metals were much lower than the Minimum Regulation Levels (MRLs). However, the Cd concentration exceeded the MRL in 1 of 987 swine feed samples in 2005, as well as in 4 of 1,239 swine feed samples and 1 of 778 poultry feed samples in 2006. The levels of Cu, Zn and P in swine feed were compared with the swine breeding standard. The results of this analysis revealed that the Cu concentrations in the samples exceeded the MRL for growing pigs by 0.97%, and that for finishing and breeding pigs by 9.9%. In addition, the Cu levels (80.98 ppm for piglet, 44.82 ppm for growing pigs, 19 ppm for finishing and breeding pigs) in swine feed showed higher levels compared to 3.5-6.0 ppm, which is the Cu requirement for swine. Furthermore, the results of the Zn analysis revealed that the samples exceeded the MRL for piglets, growing pigs, and finishing and breeding pigs by 5.7%, 7.7%, and 9.3%, respectively. Finally, the average concentration of P in swine feed was 0.74%, which is almost the same as the phosphate requirement for swine.

• Microbiology and Biotechnology Letters
• /
• v.38 no.2
• /
• pp.177-182
• /
• 2010

The goal of this study was to characterize the quality and physiological functionality of some traditional rice wines in Chungnam province, Korea. Non-sterilized and commercial sterilized traditional rice wines from five traditional rice wine factories of Chungnam province were collected and investigated for nutritional components, noxious compounds and physiological functionality. Ethanol content ranged from 16.1~18.3% and pH ranged from 3.27~4.76, and they also contained 0.15% to 0.55% of total acid. All traditional rice wines contained 10.15~139.9 mg% of amino nitrogen and 2.5~25.7% of total sugar. Among organic acids, lactic acid was contained 7.4~29.6 mg%, and succinic acid and propionic acid was also contained 0.2~2.7 mg% and 0.7~8.3 mg%, respectively. Antihypertensive angiotensin I-converting enzyme inhibitory activity were showed 37.0~86.0% in all rice wines, however, fibrinolytic activity, antioxidant activity, SOD-like activity and acetylcholinesterase inhibitory activity were low or not detected.

• Journal of Ginseng Research
• /
• v.26 no.3
• /
• pp.111-131
• /
• 2002

Korean ginseng (Panax ginseng C.A. Meyer) received a great deal of attention from the Orient and West as a tonic agent, health food and/or alternative herbal therapeutic agent. However, controversy with respect to scientific evidence on pharmacological effects especially, evaluation of clinical efficacy and the methodological approach still remains to be solved. Author reviewed those articles published since 1980 when pharmacodynamic studies on ginseng have intensively started. Special concern was paid on metabolic disorders including diabetes mellitus, circulatory disorders, malignant tumor, sexual dysfunction, and physical and mental performance to give clear information to those who are interested in pharmacological study of ginseng and to promote its clinical use. With respect to chronic diseases such as diabetes mellitus, atherosclerosis, high blood pressure, malignant disorders, and sexual disorders, it seems that ginseng plays preventive and restorative role rather than therapeutics. Particularly, ginseng plays a significant role in ameliorating subjective symptoms and preventing quality of life from deteriorating by long term exposure of chemical therapeutic agents. Also it seems that the potency of ginseng is mild, therefore it could be more effective when used concomitantly with conventional therapy. Clinical studies on the tonic effect of ginseng on work performance demonstrated that physical and mental dysfunction induced by various stresses are improved by increasing adaptability of physical condition. However, the results obtained from clinical studies cannot be mentioned in the indication, which are variable upon the scientist who performed those studies. In this respect, standardized ginseng product and providing planning of the systematic clinical research in double-blind randomized controlled trials are needed to assess the real efficacy for proposing ginseng indication. Pharmacological mode of action of ginseng has not yet been fully elucidated. Pharmacodynamic and pharmacokinetic researches reveal that the role of ginseng not seem to be confined to a given single organ. It has been known that ginseng plays a beneficial role in such general organs as central nervous, endocrine, metabolic, immune systems, which means ginseng improves general physical and mental conditons. Such multivalent effect of ginseng can be attributed to the main active component of ginseng,ginsenosides or non-saponin compounds which are also recently suggested to be another active ingredients. As is generally the similar case with other herbal medicines, effects of ginseng cannot be attributed as a given single compound or group of components. Diversified ingredients play synergistic or antagonistic role each other and act in harmonized manner. A few cases of adverse effect in clinical uses are reported, however, it is not observed when standardized ginseng products are used and recommended dose was administered. Unfavorable interaction with other drugs has also been suggested, which the information on the products and administered dosage are not available. However, efficacy, safety, interaction or contraindication with other medicines has to be more intensively investigated in order to promote clinical application of ginseng. For example, daily recommended doses per day are not agreement as 1-2g in the West and 3-6 g in the Orient. Duration of administration also seems variable according to the purpose. Two to three months are generally recommended to feel the benefit but time- and dose-dependent effects of ginseng still need to be solved from now on. Furthermore, the effect of ginsenosides transformed by the intestinal microflora, and differential effect associated with ginsenosides content and its composition also should be clinically evaluated in the future. In conclusion, the more wide-spread use of ginseng as a herbal medicine or nutraceutical supplement warrants the more rigorous investigations to assess its effacy and safety. In addition, a careful quality control of ginseng preparations should be done to ensure an acceptable standardization of commercial products.

• The Journal of Engineering Geology
• /
• v.19 no.4
• /
• pp.433-439
• /
• 2009

The compressed packer device is designed to improve the underground contamination prevention facilities of ground water wells. As for the device, the installation is simple because of the safety lock device and the compression of the casing are simple the installation is simple. There is no leakage of ground water because the pressure resistance with $4.5\;kg/cm^2$ makes it equipped with the watertightness The single casing is installed and the reaming for grouting is possible with 300 mm excavation so that installation cost can be saved. Silicon rubber is used for the compressed packer so that the extension rate is 590%. In terms of environmental pollution, it is an environmental friendly product which does not contain harmful ingredients such as Pb, Cd, and phenol. below the standard or undetectable level Furthermore, the installation costs are 35 to 62% or lower than the conventional grouting construction method and are 87% or lower than the expansion packer construction method, the new environmental technology No.47 Also, the device is designed to meet the relevant regulations such as Rules on Preserving the Ground Water Quality, The Standard on Jeju Island Ground Water Development and Facility Installation and Management, and The Plan and Guideline on Operating and Managing the Small-Scale Tap Water Facilities of Ministry of Environment and Ministry of Food, Agriculture, Forestry and Fisheries.

• Journal of the Korean GEO-environmental Society
• /
• v.13 no.1
• /
• pp.45-51
• /
• 2012

This article aims to find method to mix a harmless hardening agent and soil generated during construction to make paving materials. The main purpose of this research is to get rid of the harmfulness(Chromium (VI), etc.) of cement which has been generally and frequently used as a hardening agent and strengthen it so that it can be used for the general foundation solidification and stabilization of civil engineering/construction structures such as dredging soil treatment, marine structure foundation treatment, surface soil stabilization, and river bank erosion prevention. NSS(Natural Stabilizer Soil) used for this study takes as its chief ingredient the mixture of lime and staple fibers extracted from natural fibers. It increases the shearing strength of soil that it improves the support and durability of the foundation and prevents flooding and frost as well. The pH measured to know its eco-friendliness was 6.67~7.15, and according to the migration testing, only Pb and CN were lower than the standards, so it can be said that NSS has almost no harmful components in it. According to the result of uniaxial strength testing, when the mixture ratio of weathered soil to NSS was 6%, about 1,850kpa strength was expressed. And according to the result of CBR. testing to figure out its appropriateness as a paving material, the CBR of the foundation was 4%~6%. But when the mixture ratio of NSS is over 6%, the water immersion CBR. is over 100%; thus, it is expected that it will show great utility as a paving material.

• Journal of the Korea Concrete Institute
• /
• v.15 no.1
• /
• pp.35-42
• /
• 2003

To use ferro copper slag as aggregate in the construction, an evaluation upon the two kinds of ferro copper slag being produced was conducted to determine the basic physical, and mechanical properties, chemical component and environmental noxiousness. As a result of experiment, it was found that two kinds of ferro copper slag satisfies the physical and mechanical properties of aggregate, prescribed in KS F 2526, and that in the result of noxious heavy metal eruption test by single bach extraction, no eruption of noxious heavy metal was detected or the eruption was far below the reference value. And mortar test was conducted by replacing sand of 25, 50, 75, 100% and the performance level was presented upon reviewing the fluidity property and variable aspects of unit weight. The increase of strength in accordance with replacement rate of sand was found to be the below than the equivalent level compared to the testing specimens that did not use ferro copper slag, but those of 25% replacement rate was above than 0%. Thus, two kinds of ferro copper slag, produced in the domestic, were found to be possessing the enough physical properties to use as concrete aggregate assuming that used with sand and in particular, it was reviewed to be advantageous in manufacturing concrete or mortar that requires weight.

• Journal of Food Hygiene and Safety
• /
• v.33 no.1
• /
• pp.83-88
• /
• 2018

The purpose of this study was to investigate and evaluate the safety of the wet tissues. In this study, we analyzed sterilizing preservatives and the presence of harmful substances in 62 wet tissue samples in the market. The contents of preservatives, formaldehyde and methanol were analyzed by HPLC and headspace-GC, respectively. Cetylpyridinium chloride was detected as 7-13 ppm in 5 samples. Sodium benzoate was detected in 46 samples ranging from 200 ppm to 3500 ppm, and 9 ppm of methylparahydroxy benzoate was detected in 1 sample. Propylparahydroxy benzoate was not detected in any samples. 5 ppm of methylchloroisothiazolinone and 140 ppm of methylisothiazolinone were detected in 1 sample. Formaldehyde was detected as $0.0069-1.796{\mu}g/g$ in 59 samples. Methanol was detected ranging from 2 ppm to 51 ppm in 22 samples, and 4 samples showed more than 20 ppm of the legal limit. The pH of the wet tissues was 4.0 to 8.2. Continuous investigation and monitoring are necessary to ensure safe distribution of products.

• Journal of Food Hygiene and Safety
• /
• v.18 no.4
• /
• pp.189-194
• /
• 2003

Approved chemical preservatives have been widely used to preserve foods and increase their shelf life. There are increasing demends of the partial or complete removal of chemical preservatives from foods vecause of adverse health effect of chemicals. In this study, the possibility of natural antimicrobial compounds, Korean propolis as food preservatives are investigated. Propolis samples were extracted on various concentration of ethanol. Propolis extracts extracted with 100% ethanol showed the highest inhibitory effect aginst food spoilage microorganisms. The 100% ethanol extracts of propolis were selected and the antimicrobial activites of 100% ethanol extracts of proplis against several food spoilage microorganisms were examined. Bacillus subtilis, Micrococcus luteus, Escherichia coli, Staphylcoccus aureus, Bacillus cereus, Shigella sonnei, Salmonella choleraesuis, Erwinia rhapontici, and Vibrio parahaemolyticus as food poisoning microorganisms were chosen for the examination. The Propolis extracts had antimicrobial activity against food spoilage microorganisms. When the microorganisms were treated with propolis extracts, the population of food spolige microorganisms were decreased by 1~9 log.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.30 no.4 s.48
• /
• pp.471-477
• /
• 2004

Exposure to elevated temperatures, chemical (active oxigen), or physical stress (UV light) induces immediate physiological response, the expression of heat shock proteins in cells. Thus, cells with elevated Heat Shock Protein levels become more tolerant to stress conditions that are otherwise lethal. First, we studied on the new function of glucuronic acid (GA) as preventive material of skin aging. The application of the GA shows significant induction of Heat Shock Protein 70 kDa (HSP 70 kDa) in contrast to cells without it. GA at the concentration which can induce HSP 70 kDa, protects the cell death induced by second stress (heat shock and hydrogen peroxide) in NIH3T3 cells. Second, we studied on in vitro transdermal permeation characteristic of GA through the excised mouse skin. In this study, we compared the skin permeability of GA in water with O/W emulsion. As a result, skin permeation parameters of GA shows lag time 1.2 h, partition coefficient 0.114, permeation flult rate $0.83114 mg/cm^2/h.$ In case of lag time, O/W emulsion containing GA increase 2.48 h. Also, the total accumulation permeation content decreased in contrast to GA solution after 24 h. But it has long-term permeability of glucuronic acid. These results suggest that glucuronic acid could be a good cosmetic active ingredient.

• Journal of the Mineralogical Society of Korea
• /
• v.17 no.1
• /
• pp.37-47
• /
• 2004

Sulfates such as alunite and schwertmannite formed under oxidation condition play a important role in geochemical processes taken place at waste dumps and a creek from Dalseong mine, Daegu. Water chemistry shows pH decreases from upstream toward downstream creek, mainly due to formation of schwertmannite that is the most abundant phase along the creek. The removal of Al from the creek is preferentially attributed to formation of Al-bearing minerals and Al-sulphates. Among them, alunite is the most important Al-sink phase that occurs at higher pH than $pK_1$, Al hydrolysis constant. With high saturation index, alunite formed at the creek has a spherical form, commonly associated with schwertmannite. Secondary minerals formed on the surface of altered or weathered surfaces of heavy metals from the wasted dump that underwent severe oxidation, where alunite has characteristic habits which are spheric, radiating, and botrytis-like aggregates. Natroalunite occurs in association with alunite, or as mixtures of both of them. Because the pH decreases with distance due to formation of schwertmannite, although total contents of dissolved ions slowly lessen at least in the AMD, it is expected that the minerals precipitated at the creek can be exposed to subsequent dissolution, which may induce possible environmental problems.