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Identification of Antioxidant Activities and Stimulation of Human Keratinocytes Differentiation Effects of Syzygium claviflorum Extract (Syzygium claviflorum 추출물의 항산화 활성 및 각질형성세포 분화유도 효과)

  • Gayeon Seo;Jiyeon Moon;Yukyung Park;Juyeong Kim;Hoyong Hyun;Beomsu Jeong;Thet Thet Mar Win;Thant Zaw Win;Sangho Choi;Sangmi Eum;Dongwon Kim
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.59-65
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    • 2023
  • We validated the physiological activity of Syzygium claviflorum (Roxb.) Wall. ex A.M. Cowan & Cowan (S. claviflorum) extracts (leaves, stems, fruits, and flowers) as a cosmetic ingredient. Firstly, S. claviflorum extracts removed over 80% of free radicals at various concentrations in antioxidant experiments using the DPPH and ABTS assay. In cytotoxicity experiments using human epidermal keratinocytes, S. claviflorum extracts showed low cytotoxicity. In addition, S. claviflorum extracts significantly increased the expression of keratin (KRT)1, KRT2, KRT9, KRT10, which are differentiation markers of keratinocytes, as well as genes involved in the maintenance of skin barrier function, including involucrin (IVL), loricrin (LOR), filaggrin (FLG), and claudin1 (CLDN1). In particular, the expression of FLG protein, inhibited by interleukin (IL)-4/IL-13 in atopic dermatitis, was restored by S. claviflorum extracts in in vitro experiments. Therefore, S. claviflorum extracts with excellent antioxidant efficacy and skin barrier improvement function will be useful materials for the development of future atopic dermatitis treatments and cosmetics.

Development of Deep Learning Model for Detecting Road Cracks Based on Drone Image Data (드론 촬영 이미지 데이터를 기반으로 한 도로 균열 탐지 딥러닝 모델 개발)

  • Young-Ju Kwon;Sung-ho Mun
    • Land and Housing Review
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    • v.14 no.2
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    • pp.125-135
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    • 2023
  • Drones are used in various fields, including land survey, transportation, forestry/agriculture, marine, environment, disaster prevention, water resources, cultural assets, and construction, as their industrial importance and market size have increased. In this study, image data for deep learning was collected using a mavic3 drone capturing images at a shooting altitude was 20 m with ×7 magnification. Swin Transformer and UperNet were employed as the backbone and architecture of the deep learning model. About 800 sheets of labeled data were augmented to increase the amount of data. The learning process encompassed three rounds. The Cross-Entropy loss function was used in the first and second learning; the Tversky loss function was used in the third learning. In the future, when the crack detection model is advanced through convergence with the Internet of Things (IoT) through additional research, it will be possible to detect patching or potholes. In addition, it is expected that real-time detection tasks of drones can quickly secure the detection of pavement maintenance sections.

Spinal Tuberculosis in Children: Predictable Kyphotic Deformity after Cure of the Tuberculosis (소아 척추 결핵: 투약 후의 병의 정지와 치유점, 그리고 후만 변형)

  • Moon, Myung-Sang;Kim, Dong-Hyeon;Kim, Sang-Jae;Moon, Hanlim;Kim, Sung-Soo;Kim, Sung-Sim
    • Journal of the Korean Orthopaedic Association
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    • v.52 no.1
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    • pp.73-82
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    • 2017
  • Purpose: To assess the chronological changes of disease-related kyphosis after chemotherapy alone. Materials and Methods: A total of 101 children aged 2 to 15 years with spinal tuberculosis, accompanied by various stages of disease processes were enrolled for analysis. By utilizing the images in them, the growth plate condition and chronological changes of kyphosis after chemotherapy were analyzed at two points in time; the first assessment was at post-chemotherapy one-year and second at the final discharge. Results: Complete disc destruction in the cervical, dorsal and lumbosacral spines was observed in 2 out of 40 children (5.0%), 8 out of 30 children (26.7%), and 6 out of 31 children (19.4%), respectively. In those cases, the residual kyphosis inevitably developed. In the remaining children, the discs were intact or partially damaged. Among the 101 children kyphotic deformity was maintained without change in 20 children (19.8%). Kyphosis decreased in 14 children (13.9%), while it increased in 67 children (66.3%) with non-recoverably damaged growth plate. Conclusion: Although it is tentatively possible to predict the deformity progress or non-progress and spontaneous correction at the time of the initial treatment, its predictive accuracy is low. Therefore, assessment of the chronological changes should be performed at the end of chemotherapy. In children with progressive curve change, assessment of deformity should be continued until maturity.

A Study on the Characteristics of Global FDI on China's Balanced Development Strategy : Focusing on Korean FDI Characteristics by Major Cities in China (중국지역균형발전전략에 미치는 글로벌 FDI 특성에 관한 연구 :중국주요도시별 한국FDI 특성을 중심으로)

  • Ryoo, Sung-Woo;Mun, Cheol-Ju
    • Korea Trade Review
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    • v.43 no.4
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    • pp.155-175
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    • 2018
  • This study estimates the technical efficiency and total factor productivity(TFP) of and analyzes the relationship between TFP and exports for Korean manufacturing companies from 2000 to 2016. Specially, TFP is decomposed into Technical Change(TC), Technical Efficiency Change (TEC), and Sale Effect(SE), and compared between large and small enterprises. First, in the case of technical efficiency, the Korean economy has been very vulnerable to external shocks, such as the sharp decline following the 2008 financial crisis. The efficiency of the electronics, automobile, and machinery sectors is low and needs to be improved. In addition, the technological efficiency of large enterprises is higher than that of SMEs in most manufacturing sub-sectors except for non-ferrous metals. In the case of TFP, most changes are due to TC, and the effective combination of labor, capital and the effect of scale have little effect, suggesting that improvement of internal structure is urgent. In addition, volatility due to the impact of the financial crisis in 2008 was much larger in SMEs than in large companies, so external economic impacts are more greater for SMEs than large enterprises. The relationship between TFP decomposition factors and exports shows that TC has a positive effect only on exports of SMEs. Therefore, in order to increase exports, in the case of SMEs, R&D support to promote technological development is needed. In the case of large companies, it is necessary to establish differentiated strategies for each export market, competitor company, and item to link efficiency and scale effect of exports.

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Jeong Yak-Yong's Zhong-yong: The Habit of Moral Behavior Through Grasp (정약용의 중용: 장악을 통한 도덕적 행위의 습관화)

  • Gao, Ming-Wen;Mo, A-Yeong
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.8 no.8
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    • pp.793-803
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    • 2018
  • Since Confucius presentied 'zhong-yong' and Zi Si wrote Zhong-Yong (The Doctring of the Mean), specially since Zhu Xi edited Zhong-Yong as one of Si-Shu (The Four Books) and interpreted it, zhong-yong was not only recognized as the extreme of morality but also as a significant category of Confucianism. The purpose of this paper is to clarify how Jeong Yak-Yong criticized Zhu Xi's interpretation of zhong-yong, and furthermore, to search how Jung Yak-yong explain the zhong-yong by tree concepts of 'grasp', 'moral behavior', and 'habit'. Zhu Xi interpreted zong as a measured absolute middle of two-side and a non-launched original nature. Interpreted yong as a common truth. Therefore he interpreted zhong-yong as a common truth of neither excessive nor enough. Accordingly, Zhu Xi's zhong-yong can be understood as absolute zhong-yong without human's reflection and moral behavior. But Jeong Yak-Yong interpreted zhong as the state of a man's very hard-concentrate and grasp of situation, and interpreted yong as the state of a man's very hard-effort moral behavior and it's habit. Therefore he explained zhong-yong as a habit of moral behavior through grasp.

What We Want for Virtual Humans: Classification of Consumer Expectation Value on Virtual Influencer by Age Based on Q-methodology (가상 인간에 대한 우리들이 원하는 모습: Q방법론을 기반으로 한 연령대에 따른 소비자 기대 가치 분류)

  • Ji-Chan Yun;Do-Hyung Park
    • Knowledge Management Research
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    • v.24 no.2
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    • pp.137-159
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    • 2023
  • This study focuses on consumers' perceptions of virtual influencers, which many companies recently used for marketing. This study uses the Q methodology to derive what kind of perception consumers have about virtual influencers who work with various appearances, background stories, and worldviews as components. In addition, we want to see how the expected value of virtual influencers differs by age group. To this end, 34 statements were produced through preliminary interviews and literature reviews. This study showed that some consumers preferred appearances similar to humans, despite recognizing that virtual influencers are fictional characters. Some other consumers preferred to feel like a fictional character by maintaining virtuality, confirming that there are both opposite consumers. In addition, consumers expect virtual influencers to have consistency and expertise in the content field covered, and some consumers do not prefer to show an overly commercial appearance. This study will likely provide implications for companies that want to utilize virtual influencers in considering which ones to use for target customers in marketing activities.

A Study on the case of Application of Women's Personnel in the Australian Defence Force (호주군 여성인력의 활용과 우리군에 주는 시사점)

  • In-Chan Kim;Jong-Hoon Kim;Jun-Hak Sim;Kang-Hee Lee;Sang-Keun Cho;Sang-Hyuk Park;Myung-Sook Hong
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.5
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    • pp.269-273
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    • 2023
  • After participating in the Second Boer War in 1899, the Australian Army participated in world wars such as World War I, World War II, the Korean War, and the Vietnam War. To overcome the decline in the social recognition of soldiers and the continuous shortage of troops caused by the protracted war, the status and role of female personnel were expanded. The use of female manpower, which started as medical support during the Second Boer War, expanded to combat support missions such as communications, maintenance, driving, secret document management, and radar surveillance during World War II. After the Vietnam War, the Chiefs of Staff of the Australian Army, Navy and Air Force established a committee to expand women's participation in the military, improved service conditions for female personnel and supplemented regulations so that they were treated as soldiers, not women, and reached a turning point in expanding the role of female personnel in the Australian military. As a result, all combat positions, including special forces, were opened to women in 2014, and a plan was established to increase the proportion of women in each service by 2030. As a result, all combat positions, including special forces, were opened to women in 2014, and the Australian Armed Forces set a plan to increase the proportion of women by 2030. Like the Australian military, South Korea is also experiencing a demographic cliff and shortage of troops due to the continuing low birthrate problem. Through the history and current state of the use of female personnel in the Australian military, we would like to draw implications for the direction our military should go.

Assessment of temperature-dependent water quality reaction coefficients and monthly variability of residual chlorine in water distribution networks (수온 변화에 따른 상수관망 내 수질반응계수 추정 및 월별 잔류염소농도 분포 변화 분석)

  • Jeong, Gimoon;Choi, Taeho;Kang, Doosun;Lee, Juwon;Hwang, Taemun
    • Journal of Korea Water Resources Association
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    • v.56 no.11
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    • pp.705-720
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    • 2023
  • In South Korea, ongoing incidents related to drinking water quality have eroded consumer trust. Specifically, beyond quality incidents, there have been complaints about taste, odor, and other issues stemming from the presence of chlorine. To address this, water service operators are employing various management strategies from both temporal (scheduling) and spatial (rechlorination) perspectives to ensure uniform and safe distribution of chlorine residuals. In this study, we focus on the optimal monthly management of chlorine residuals, based on water distribution network analysis. Water quality reaction coefficients, including bulk fluid and wall reaction coefficients, were estimated through lab-scale tests and EPANET water quality simulations, respectively, accounting for temperature variations in a large-scale water distribution network. Utilizing these estimated coefficients, we examined the monthly variations in chlorine residual distribution under different chlorine injection conditions. The results indicate that the efficient concentration for chlorine injection, which satisfies the residual chlorine limit range, varies with temperature changes. Consequently, it is imperative to establish a specific and quantitative chlorine injection plan that considers the accurate spatial distribution of monthly chlorine residuals.

Effect of Mechanical and Toughening Characteristics of Epoxy/Carbon Fiber Composite by Polyamide 6 Particles, CTBN Addition Technology (Polyamide 6 입자 및 CTBN 첨가 기술에 따른 에폭시/탄소섬유 복합재의 강인화 효과 및 기계적 특성)

  • Sung-Youl Bae;Kyo-Moon Lee;Sanjay Kumar;Ji-Hun Seok;Jae-Wan Choi;Woo-Hyuk Son;Yun-Hae Kim
    • Composites Research
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    • v.36 no.5
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    • pp.355-360
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    • 2023
  • Epoxy-based carbon fibers reinforced plastic (CFRP) exhibit limitations in their suitability for industrial applications due to high brittleness characteristics. To address this challenge, extensive investigations are underway to enhance their toughness properties. This research focuses on evaluating the toughening mechanisms achieved by Polyamide 6 particles(p-PA6) and Carboxyl-Terminated Butadiene-Acrylonitrile (CTBN) elastomer, with a specific emphasis on utilizing minimal additive quantities. The study explores the impact of varying concentrations of p-PA6 and CTBN additives, namely 0.5, 1, 2.5, and 5 phr, through comprehensive Mode I fracture toughness and tensile strength analyses. The inclusion of p-PA6 demonstrated improvements in toughness when introduced at a relatively low content of 1phr. This improvement manifested as a sustained fracture behavior, contributing to enhanced toughness, while simultaneously maintaining the material's tensile strength. Furthermore, the investigation revealed that the incorporation of p-PA6 affected in particle aggregation, thus influencing the overall toughening mechanism. Incorporation of CTBN, an elastomeric modifier, exhibited a pronounced increase in fracture toughness at higher concentrations of 2.5 phr and beyond. However, this increase in toughness was accompanied by a reduction in tensile strength, resulting in fracture behavior similar to conventional CFRP exhibiting brittleness. The synergy between pPA6, CTBN and CFRP appeared to marginally enhance tensile strength under specific content conditions. As a result of this study, optimized conditions for the application of the p-PA6, CTBN toughening technology have been identified and established.

Camera App of Smartphone with Multi-Focus Shooting and Focus Post-processing Functions (다초점 촬영과 초점후처리 기능을 가진 스마트폰 카메라 앱)

  • Chae-Won Park;Kyung-Mi Kim;Song-Yeon Yoo;Yu-Jin Kim;Kitae, Hwang;In-Hwang Jung;Jae-Moon Lee
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.24 no.1
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    • pp.189-196
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    • 2024
  • Currently, it is almost impossible to move the focus of a previously taken photo to a different location. This paper challenges a technology that can move the focus of a captured photo to another location after shooting. To achieve this goal, this paper proposed and implemented a method for taking photos with various focuses at the moment the camera took pictures and storing them in a single JPEG file to extract photos focused on the user's preferred location. In this paper, two methods are implemented: taking various photos by quickly moving the focal length of the lens from close to far away, and taking various photos focused on each object by recognizing objects in the camera viewfinder. Various photos taken are stored in a single JPEG to maintain compatibility with traditional photo viewers. At this time, this JPEG file used the All-in-JPEG format proposed in previous research to store a variety of images. This paper verified its practicality by implementing these technologies in an Android app named OnePIC.