• Title/Summary/Keyword: 유전자 예측

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Real-time optimal pump operation model development (경제적인 용수공급을 위한 실시간 송수펌프의 최적운영 모형 개발)

  • Kim, Kang Min;Choi, Jeong Wook;Kang, Doosun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.185-185
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    • 2016
  • 일반적인 송 배수시스템의 운영은 지대가 높은 곳에 위치한 배수지(tank)에 용수를 저장한 후, 자연유하에 의해 수요절점으로 용수를 공급한다. 이때 배수지에 용수를 송수하기 위한 펌프장 운영에서 많은 전기에너지가 소모된다. 일반적으로 송수펌프의 운영은 다년간의 운영자료를 기반으로 운영자의 판단에 의해 이루어지거나, SCADA(Supervisory Control and Data Acquisition)시스템을 통해 관측되는 배수지 수위를 기준으로 펌프 작동여부를 결정하고 있다. 본 연구에서는 이러한 기존 펌프운영방법을 개선하고 좀 더 효율적인 운영방법을 모색하기 위해 실시간 송수펌프 최적운영 모형을 개발하였다. 최적화 기법으로는 유전자 알고리즘(genetic algorithm)을 사용하였으며, 다양한 제약조건(operational constraints)을 적용하고 급수지역의 24시간 용수사용량을 미리 예측하여 실제 시스템의 운영형태와 근접하게 반영하였다. 또한 최적화 과정에서 상수관망해석 프로그램(EPANET)을 연계하여 수요절점의 수압조건 및 시스템의 운영상황을 모의하였다. 개발된 모형을 국내 P시의 광역상수도 시스템에 실제 적용하였으며, 현장 실시간 운영 데이터를 입수하여 전력사용량, 배수지수위, 이산화탄소 발생량 등을 비교, 분석하였다. 개발 모형을 이용하여 펌프운영을 실시하였을 경우, 기존의 운영방식과 비교하여 경제적/환경적으로 뚜렷한 개선 효과를 확인할 수 있었다.

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Review of the Application of Artificial Intelligence in Blasting Area (발파 분야에서의 인공지능 활용 현황)

  • Kim, Minju;Ismail, L.A.;Kwon, Sangki
    • Explosives and Blasting
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    • v.39 no.3
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    • pp.44-64
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    • 2021
  • With the upcoming 4th industrial revolution era, the applications of artificial intelligence(AI) and big data in engineering are increasing. In the field of blasting, there have been various reported cases of the application of AI. In this paper, AI techniques, such as artificial neural network, fuzzy logic, generic algorithm, swarm intelligence, and support vector machine, which are widely applied in blasting area, are introduced, The studies about the application of AI for the prediction of ground vibration, rock fragmentation, fly rock, air overpressure, and back break are surveyed and summarized. It is for providing starting points for the discussion of active application of AI on effective and safe blasting design, enhancing blasting performance, and minimizing the environmental impact due to blasting.

Complete genome sequence of Tamlana sp. UJ94 degrading alginate (알긴산을 분해하는 세균 Tamlana sp. UJ94의 완전한 유전체 서열)

  • Jung, Jaejoon;Bae, Seung Seob;Chung, Dawoon;Baek, Kyunghwa
    • Korean Journal of Microbiology
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    • v.54 no.4
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    • pp.463-464
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    • 2018
  • Tamlana sp. UJ94 isolated from seawater can degrade alginate. To identify the genomic basis of this activity, the genome was sequenced. The genome was composed of 4,116,543 bp, 3,609 coding sequences, and 35.2 mol% G + C content. A BLASTp search predicted the presence of 9 alginate lyases as well as 6 agarases, 5 amylases, 4 carrageenases, 1 cellulase, 4 pectate lyases, and 7 xylanases, indicating its ability to degrade diverse polysaccharides. The genome of strain UJ94 is a source of polysaccharide-degrading enzymes for bioconversion processes.

Social Network-based Hybrid Collaborative Filtering using Genetic Algorithms (유전자 알고리즘을 활용한 소셜네트워크 기반 하이브리드 협업필터링)

  • Noh, Heeryong;Choi, Seulbi;Ahn, Hyunchul
    • Journal of Intelligence and Information Systems
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    • v.23 no.2
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    • pp.19-38
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    • 2017
  • Collaborative filtering (CF) algorithm has been popularly used for implementing recommender systems. Until now, there have been many prior studies to improve the accuracy of CF. Among them, some recent studies adopt 'hybrid recommendation approach', which enhances the performance of conventional CF by using additional information. In this research, we propose a new hybrid recommender system which fuses CF and the results from the social network analysis on trust and distrust relationship networks among users to enhance prediction accuracy. The proposed algorithm of our study is based on memory-based CF. But, when calculating the similarity between users in CF, our proposed algorithm considers not only the correlation of the users' numeric rating patterns, but also the users' in-degree centrality values derived from trust and distrust relationship networks. In specific, it is designed to amplify the similarity between a target user and his or her neighbor when the neighbor has higher in-degree centrality in the trust relationship network. Also, it attenuates the similarity between a target user and his or her neighbor when the neighbor has higher in-degree centrality in the distrust relationship network. Our proposed algorithm considers four (4) types of user relationships - direct trust, indirect trust, direct distrust, and indirect distrust - in total. And, it uses four adjusting coefficients, which adjusts the level of amplification / attenuation for in-degree centrality values derived from direct / indirect trust and distrust relationship networks. To determine optimal adjusting coefficients, genetic algorithms (GA) has been adopted. Under this background, we named our proposed algorithm as SNACF-GA (Social Network Analysis - based CF using GA). To validate the performance of the SNACF-GA, we used a real-world data set which is called 'Extended Epinions dataset' provided by 'trustlet.org'. It is the data set contains user responses (rating scores and reviews) after purchasing specific items (e.g. car, movie, music, book) as well as trust / distrust relationship information indicating whom to trust or distrust between users. The experimental system was basically developed using Microsoft Visual Basic for Applications (VBA), but we also used UCINET 6 for calculating the in-degree centrality of trust / distrust relationship networks. In addition, we used Palisade Software's Evolver, which is a commercial software implements genetic algorithm. To examine the effectiveness of our proposed system more precisely, we adopted two comparison models. The first comparison model is conventional CF. It only uses users' explicit numeric ratings when calculating the similarities between users. That is, it does not consider trust / distrust relationship between users at all. The second comparison model is SNACF (Social Network Analysis - based CF). SNACF differs from the proposed algorithm SNACF-GA in that it considers only direct trust / distrust relationships. It also does not use GA optimization. The performances of the proposed algorithm and comparison models were evaluated by using average MAE (mean absolute error). Experimental result showed that the optimal adjusting coefficients for direct trust, indirect trust, direct distrust, indirect distrust were 0, 1.4287, 1.5, 0.4615 each. This implies that distrust relationships between users are more important than trust ones in recommender systems. From the perspective of recommendation accuracy, SNACF-GA (Avg. MAE = 0.111943), the proposed algorithm which reflects both direct and indirect trust / distrust relationships information, was found to greatly outperform a conventional CF (Avg. MAE = 0.112638). Also, the algorithm showed better recommendation accuracy than the SNACF (Avg. MAE = 0.112209). To confirm whether these differences are statistically significant or not, we applied paired samples t-test. The results from the paired samples t-test presented that the difference between SNACF-GA and conventional CF was statistical significant at the 1% significance level, and the difference between SNACF-GA and SNACF was statistical significant at the 5%. Our study found that the trust/distrust relationship can be important information for improving performance of recommendation algorithms. Especially, distrust relationship information was found to have a greater impact on the performance improvement of CF. This implies that we need to have more attention on distrust (negative) relationships rather than trust (positive) ones when tracking and managing social relationships between users.

The Utility of MAGE Gene Detection in Bronchial Washing Fluid for Patients with Peripheral NSCLC (말초 비소세포폐암 환자에서 기관지 세척액 MAGE 유전자 진단의 유용성)

  • Kim, Suhyun;Kim, Hojoong;Kwon, O Jung;Chung, Man Pyo;Suh, Gee Young;Koh, Won-Jung;Ham, Cho Rom;Nam, Hae Seong;Um, Sang-Won;Kwon, Yong Soo;Park, Sung-Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.1
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    • pp.15-21
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    • 2008
  • Background: The melanoma antigen-encoding (MAGE) genes are known to be expressed in various cancer cells, including non-small cell lung cancer (NSCLC), and are silent in all normal tissues except for the testis. In patients with peripheral NSCLC, bronchial washing fluid can be used to detect the MAGE genes, suggesting a diagnosis of lung cancer. In order to evaluate the diagnostic utility of the MAGE test in patients with peripheral NSCLC, bronchial washing fluid was investigated in patients with peripheral pulmonary nodules, which were invisible as detected by bronchoscopy. Methods: Bronchial washing fluid from 37 patients was used for cytological examinations and MAGE gene detection, using RT-nested-PCR of common A1-A6 mRNA. Results were compared to a final diagnosis of patients as confirmed by pathology. Results: Among the 37 subjects, NSCLC was diagnosed in 21 patients, and benign pulmonary diseases were diagnosed in 16 patients. MAGE mRNA was detected in 10 of 21 (47.6%) NSCLC patients, while conventional cytology examinations were positive for MAGE expression in 2 of 21 (9.5%) cases. MAGE expression was observed in 4 of 16 (25%) benign pulmonary disease patients. Conclusion: The MAGE test of bronchial washing fluid can be used as a sensitive predictor of peripheral NSCLC patients.

Estimation of storability for Korean apples (Malus domestica) using Md-ACS1 and Md-ACO1 DNA marker (Md-ACS1 및 Md-ACO1 분자표지를 이용한 국내육성사과의 저장성 예측)

  • Kwon, Young Soon;Kwon, Soon-Il;Kim, Seon Ae;Kweon, Hun-Joong;Yoo, Jingi;Ryu, Seulgi;Kang, In-Kyu;Kim, Jeong-Hee
    • Food Science and Preservation
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    • v.24 no.7
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    • pp.891-897
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    • 2017
  • Apple (Malus domestica) is a climacteric fruit because of its high respiration and ethylene production. Ethylene affects the fruit by decreasing its quality and storability. Md-ACS1 and Md-ACO1 genes are involved in ethylene biosynthesis in apple; the Md-ACS1-2 and Md-ACO1-1 alleles are associated with low ethylene production. We conducted an analysis to study Md-ACS1 and Md-ACO1, and to examine ethylene production and softening rate of fruit at room temperature ($20^{\circ}C$) storage in 'Fuji (FJ)', 'Golden Supreme (GS)', and 5 cultivars of Korean apples ('RubyS (RS)', 'Hongro (HR)', 'Arisoo (AS)', 'Summer King (SK)', 'Greenball (GB)'). The result showed that an increase in the number of the alleles (ACS1-2, ACO1-1) decreased the ethylene production and softening rate. The presence of ACS1-1/1, ACO1-1/2 was confirmed in GS and the highest ethylene production and softening rate was observed. Ethylene production and softening rate of SK and GB expressing ACS1-1/2, ACO1-1/2 were higher than that of HR and AS, expressing ACS1-2/2, ACO1-1/2, but lower than GS. FJ with ACS1-2/2, ACO1-1/1 showed the lowest ethylene production and softening rate among all cultivars except RS. The Md-ACS1 and Md-ACO1 DNA markers could potentially be used to estimate storability and applied in marker assisted selection the improve the efficiency of apple breeding.

Development of a Traffic Accident Prediction Model and Determination of the Risk Level at Signalized Intersection (신호교차로에서의 사고예측모형개발 및 위험수준결정 연구)

  • 홍정열;도철웅
    • Journal of Korean Society of Transportation
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    • v.20 no.7
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    • pp.155-166
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    • 2002
  • Since 1990s. there has been an increasing number of traffic accidents at intersection. which requires more urgent measures to insure safety on intersection. This study set out to analyze the road conditions, traffic conditions and traffic operation conditions on signalized intersection. to identify the elements that would impose obstructions in safety, and to develop a traffic accident prediction model to evaluate the safety of an intersection using the cop relation between the elements and an accident. In addition, the focus was made on suggesting appropriate traffic safety policies by dealing with the danger elements in advance and on enhancing the safety on the intersection in developing a traffic accident prediction model fir a signalized intersection. The data for the study was collected at an intersection located in Wonju city from January to December 2001. It consisted of the number of accidents, the road conditions, the traffic conditions, and the traffic operation conditions at the intersection. The collected data was first statistically analyzed and then the results identified the elements that had close correlations with accidents. They included the area pattern, the use of land, the bus stopping activities, the parking and stopping activities on the road, the total volume, the turning volume, the number of lanes, the width of the road, the intersection area, the cycle, the sight distance, and the turning radius. These elements were used in the second correlation analysis. The significant level was 95% or higher in all of them. There were few correlations between independent variables. The variables that affected the accident rate were the number of lanes, the turning radius, the sight distance and the cycle, which were used to develop a traffic accident prediction model formula considering their distribution. The model formula was compared with a general linear regression model in accuracy. In addition, the statistics of domestic accidents were investigated to analyze the distribution of the accidents and to classify intersections according to the risk level. Finally, the results were applied to the Spearman-rank correlation coefficient to see if the model was appropriate. As a result, the coefficient of determination was highly significant with the value of 0.985 and the ranks among the intersections according to the risk level were appropriate too. The actual number of accidents and the predicted ones were compared in terms of the risk level and they were about the same in the risk level for 80% of the intersections.

Design and Implementation of Trip Generation Model Using the Bayesian Networks (베이지안 망을 이용한 통행발생 모형의 설계 및 구축)

  • Kim, Hyun-Gi;Lee, Sang-Min;Kim, Kang-Soo
    • Journal of Korean Society of Transportation
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    • v.22 no.7 s.78
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    • pp.79-90
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    • 2004
  • In this study, we applied the Bayesian Networks for the case of the trip generation models using the Seoul metropolitan area's house trip survey Data. The household income was used for the independent variable for the explanation of household size and the number of cars in a household, and the relationships between the trip generation and the households' social characteristics were identified by the Bayesian Networks. Furthermore, trip generation's characteristics such as the household income, household size and the number of cars in a household were also used for explanatory variables and the trip generation model was developed. It was found that the Bayesian Networks were useful tool to overcome the problems which were in the traditional trip generation models. In particular the various transport policies could be evaluated in the very short time by the established relationships. It is expected that the Bayesian Networks will be utilized as the important tools for the analysis of trip patterns.

Optimizing Similarity Threshold and Coverage of CBR (사례기반추론의 유사 임계치 및 커버리지 최적화)

  • Ahn, Hyunchul
    • KIPS Transactions on Software and Data Engineering
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    • v.2 no.8
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    • pp.535-542
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    • 2013
  • Since case-based reasoning(CBR) has many advantages, it has been used for supporting decision making in various areas including medical checkup, production planning, customer classification, and so on. However, there are several factors to be set by heuristics when designing effective CBR systems. Among these factors, this study addresses the issue of selecting appropriate neighbors in case retrieval step. As the criterion for selecting appropriate neighbors, conventional studies have used the preset number of neighbors to combine(i.e. k of k-nearest neighbor), or the relative portion of the maximum similarity. However, this study proposes to use the absolute similarity threshold varying from 0 to 1, as the criterion for selecting appropriate neighbors to combine. In this case, too small similarity threshold value may make the model rarely produce the solution. To avoid this, we propose to adopt the coverage, which implies the ratio of the cases in which solutions are produced over the total number of the training cases, and to set it as the constraint when optimizing the similarity threshold. To validate the usefulness of the proposed model, we applied it to a real-world target marketing case of an online shopping mall in Korea. As a result, we found that the proposed model might significantly improve the performance of CBR.

Development of an Intelligent Trading System Using Support Vector Machines and Genetic Algorithms (Support Vector Machines와 유전자 알고리즘을 이용한 지능형 트레이딩 시스템 개발)

  • Kim, Sun-Woong;Ahn, Hyun-Chul
    • Journal of Intelligence and Information Systems
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    • v.16 no.1
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    • pp.71-92
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    • 2010
  • As the use of trading systems increases recently, many researchers are interested in developing intelligent trading systems using artificial intelligence techniques. However, most prior studies on trading systems have common limitations. First, they just adopted several technical indicators based on stock indices as independent variables although there are a variety of variables that can be used as independent variables for predicting the market. In addition, most of them focus on developing a model that predicts the direction of the stock market indices rather than one that can generate trading signals for maximizing returns. Thus, in this study, we propose a novel intelligent trading system that mitigates these limitations. It is designed to use both the technical indicators and the other non-price variables on the market. Also, it adopts 'two-threshold mechanism' so that it can transform the outcome of the stock market prediction model based on support vector machines to the trading decision signals like buy, sell or hold. To validate the usefulness of the proposed system, we applied it to the real world data-the KOSPI200 index from May 2004 to December 2009. As a result, we found that the proposed system outperformed other comparative models from the perspective of 'rate of return'.