• Title/Summary/Keyword: 유발효과

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Evaluation of the anticonvulsant effect of tropinone derivatives (Tropinone 유도체의 항경련성 효과 평가)

  • 김익수;서덕준
    • Journal of Life Science
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    • v.12 no.5
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    • pp.505-514
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    • 2002
  • The aim of this study was to evaluate the anticonvulsant activity of four agents derived from tropinone (T-1: 2,4-dipyrrolylmethenylnortropinone, T-2: 2,4-diphenylmethenylnortropinone, T-3 : 2,4-difurfurylmethenylnortropinone, T-4 : 2,4-dimethoxyphenylmethenylnortropinone) in NIH Swiss mouse. Pentylenetetrazole (nZ) was injected via intraperi-toniurn in mouse and Maximal Electroshock (MES) stimulation was through both conjunctivas by electrodes. Tropinone derivatives were treated at 15 minutes before PTZ or MES procedure. PIZ of 25 mg/kg induced generalized seizure in mouse, effects of tropinone derivatives on PTZ-induced seizure were monitored. Compared with control group, T-4 decreased seizure grade most effectively. Also T-4 increased onset time of PTZ-induced seizure. This result showed that T-4 is most effective on PTZ-induced seizure. In MES-induced seizure, T-1 decreased seizure grade and recovery time. nNOS expression in hippocampus and cortex were increased in nZ- and MES-induced seizure animals compared with control. Pretreatment of tropinone derivatives in PTZ-induced seizure did not affected nNOS expression in brain tissues, but T-1 and T-4 decreased nNOS expression in cortex of MES-induced seizure animals. These findings suggest that tropinone derivatives have specific anticonvulsant activities according to PTZ- and MES-induced seizure. 2,4- dimethoxyphenylmethenylnoroopinone is most effective in PTZ-induced seizure and 2,4-di methoxyphenylmethenylnortropinone is most effective in MES-induced seizure.

A Study of the Regional Economic Multiplier Impacts of Local Cultural Festival : In Case of Jeonju International Film Festival (지역문화축제의 지역경제파급효과에 관한 연구 : 전주 국제 영화제를 중심으로)

  • Kim, Yon-Hyong
    • The Korean Journal of Applied Statistics
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    • v.21 no.1
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    • pp.125-140
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    • 2008
  • The purpose of this study is to analysis the economic impacts of regional cultural festival via using the regional input-output model. In order to achieve this purpose, calculate output, value added and employment multiplier impacts of the Jeonju International Film Festival. The impacts of the JIFF on regional economic follow as ; Output is 112 hundred million won, value added is 53 hundred million won and employes is 254 labors. We need a new following strategies to obtain highly positive impacts from regional cultural festival. It needs to made networks among sight-seeing places, cultural remains, restaurants, hotels and entertainment institutions, in order to made visitors and customers expend much.

The Effects of Coal Thermal Power Plant Exports on the National Economy (석탄화력발전 해외수출의 경제적 파급효과 분석)

  • Jin, Se-Jun;Yoo, Seung-Hoon
    • Journal of Energy Engineering
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    • v.22 no.1
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    • pp.17-27
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    • 2013
  • Korean domestic electricity market is saturated through trying to find ways to overcome the limitations of the domestic electricity industry with overseas electricity markets. Korean electricity industry in the overseas market in order to pursue continuous growth, competitive and aggressive investment in overseas market is promoting. This paper attempts to apply input-output analysis to estimate the role of coal thermal power plant sector exports national economy. More specifically, this study shows what national economy effect of production-inducing effect, value-added inducing effect, and employment-inducing effect are explored with demand-driven model. After define coal thermal power plant sector what small sized of Input-Output table 168 sectors among 17 sectors, this study pays particular and close attention to coal thermal power plant sector by taking the sector as exogenous specification and then investigating economic impacts of it. This study uses coal thermal power plant exportation case of Vietnam project, production-inducing effect, value-added inducing effect, and employment-inducing effect are 2,853 billion won, 973 billion won and 14,761 persons, respectively.

Using the Demand-driven Model-based Inter-industry Analysis to Examine the Economic Effects of Petroleum Refinery Sector (수요유도형 모형 기반 산업연관분석을 적용한 정유 부문의 경제적 파급효과 분석)

  • Kim, Ho-Young;Song, Tae-Ho;Yoo, Seung-Hoon
    • Journal of Energy Engineering
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    • v.24 no.1
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    • pp.104-113
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    • 2015
  • This study tried to conduct a comparative analysis on the yearly economic effects of petroleum products sector. Inter-industry tables published 1990~2012 are used in this study. Especially petroleum products sector is specified as exogenous to identify the economic effects on own and other sectors. Production-inducing effect, value-added creation effect, and employment-inducing effect are quantified based on demand-driven model. The results of the analysis, the case of annual production inducing-effect, show the downward trend from 1993 to 2008. and It seemed to be constant from 2009 to 2012. The value-added inducing-effect, from 1990 to 1998, shows a rising trend. the since 1998, it was found to decline steadily. Employment-inducing effect is shown a steadily decreasing trend from 1990 to 2008, and has been kept constant from 2010 at the level under 1.300(person/one billion won). These results of in comparison with the past are significant in that it can be objectively evaluate the domestic oil industry at the present time. and it can be usefully utilized to predict the economic effect of future oil industry.

A study on the estimation of the K-address information industry and its economic effect (주소정보산업 규모 산정 및 경제적 효과 분석)

  • Kim, Daeyong
    • Journal of Cadastre & Land InformatiX
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    • v.54 no.1
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    • pp.33-48
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    • 2024
  • This study aims to establish the scope and statistics of the K-address information industry in Korea, estimating its size and prospects and estimates the economic effects through K-address information industry based on Input-Output analysis. Considering the characteristics and sectoral structure of the K-address information industry, the study delineates the scope and specific sectors, constructing sectoral statistics linked to the KSIC and the Bank of Korea's industrial classification. The study estimates the sectoral industry size, taking into account potential markets. Furthermore, it analyzes the economic impact of each sector within the K-address information industry. To figure out the economic effects, the study conducts Input-Output analysis by setting the K-address information industry as an exogenous sector in the input-output table. The results indicate that the overall size of the K-address information industry is estimated to grow from 406.1 billion KRW in 2021 to 3.65 trillion KRW in 2030. The economic effects of the K-address information industry vary by sector, emphasizing the importance of synergies and integration with related sectors, particularly those with significant inducement effects in high value-added manufacturing and service sectors. Furthermore, the industry's sensitivity to economic fluctuations is evident through the input-output analysis of inter-industry chain effects.

Estimating the Economic Impact of '2011 Seoul Motor Show' Using Regional Input-Output Model: Based on Expenditures of Exhibition Attendees (지역산업연관모델을 이용한 '2011 서울모터쇼'의 경제적 파급효과 분석: 전시참관객의 지출액을 바탕으로)

  • Kim, Dae-Kwan;Han, Youn-Joo;Lee, Sang-Min;Choe, Yeong-Bae;Song, Soo-Yeop
    • The Journal of the Korea Contents Association
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    • v.11 no.10
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    • pp.187-196
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    • 2011
  • This study aimed to estimate the economic impact of the '2011 Seoul Motor Show' using a direct survey-based regional input-output(I-O) model. Based on the regional I-O table, Exhibition multipliers were derived with respect to output, income, employment, value-added and indirect tax. Attendees' survey was conducted to estimate per capita expenditure. The results of this study indicated that all attendees of '2011 Seoul Motor Show' generated 53.1 billion Won of output impact, 11.7 billion Won of income impact, 24.1 billion Won of Value-added impact, 2.6 billion Won of tax impact, and 1,030 part-time and full-time jobs throughout direct and indirect effects. Another result of this study was that output multiplier of the exhibition industry was similar with other industries, however, income, employment and value-added multipliers were relatively larger than those of other industries.

Hepatoprotective effects of Electro-Acupuncture at Taechung (LR3) and Yangji (TE4) on experimental liver injury in rats (태충(太衝) 및 양지(陽池)의 전침(電針)이 실험적(實驗的)으로 유발(誘發)된 백서(白鼠)의 간보호효과(肝保護效果)에 미치는 영향(影響))

  • Na, Chang-Su;Youn, Dae-Hwan
    • Korean Journal of Acupuncture
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    • v.23 no.2
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    • pp.167-176
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    • 2006
  • 목 적 : 본 연구는 태충(太衝) 및 양지혈(陽池穴) 에 대한 전침(電鍼)이 galactosamine 을 이용한 백서의 간독성(肝毒性)을 실험적으로 유발시킨 모델에서 예방효과(豫防效果)를 알아보고자 혈청중의 $\gamma\;-GTP$, GOT, GPT, LDH, total bilirubin, total cholesterol, triglyceride 의 변화를 관찰하였다. 방 법 : 간독성은 각 군들은 간독성을 유발하지 않고 무처치한 정상군, 간독성을 유발하고 난 후 무처치한 대조군, 각각 10 Hz, 50 Hz, 100 Hz 전침을 20 일간 10 회 시행한 후 간독성을 유발한 Pre 10, Pre 50, Pre 100군 등으로 분류하였다. 결 과 : 태충(太衝) 양지혈(陽池穴)에 대한 전침(電鍼) 치료(治療)의 예방효과(豫防效果)에서는 Pre 10 군에서는 ${\gamma}\;-GTP$, GOT, GPT, total cholesterol, triglyceride이 Pre 50군에서는 ${\gamma}\;-GTP$GOT, GPT, LDH, total bilirubin, total cholesterol이, Pre 100 군에서는 ${\gamma}\;-GTP$, GOT, LDH, total bilirubin, total cholesterol이 대조군에 비해 감소하였다. 결 론 : 위의 결과를 종합해보면 간독성에 대하여 태충(太衝) 양지혈(陽池穴)의 전침(電鍼)을 시행한 모든 군에서 간능과 지절대사에서 간손상에 대한 유의한 예방효과를 나타내었다.

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Comparison of Stain Rate-Dependent Consolidation Behaviors of Olga-C Embankment with and without Vertical Drains (배수재 설치 및 미설치 구역으로 구성된 Olga-C 성토지반의 변형률 속도 의존적인 압밀거동 비교)

  • Kim, Yun-Tae
    • Journal of the Korean Geotechnical Society
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    • v.16 no.3
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    • pp.39-46
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    • 2000
  • 본 논문에서는 배수재가 설치된 구역과 설치되지 않은 구역으로 구성된 Olga-C 시험성토지반의 변형률속도 의존적인 압밀거동을 서술하였다. 배수재가 설치된 지반이 압밀거동에 대한 변형률속도의 영향을 해석하기 위하여 응력-변형률-변형률 속도의 관계식(v-$\varepsilon$v- v)을 이용한 축대칭 비선형 점소성 모델을 제안하였다. 제안된 모델은 실험실과 현장의 변형률속도 차이뿐만 아니라 간극수압의 소산과 생성의 복합적인 압밀과정을 고려할 수 있다. 연직 및 반경방향의 배수효과에 의해 배수재가 설치된 지반(Zone B)에서 유발되는 변형률 속도는 배수재가 설치되지 않은 연약지반 (Zone A)의 변형률 속도보다 크다. 유발된 변형률 속도의 영향으로 Zone B의 선행압밀하중도 Zone A에서 유발되는 선행압밀하중보다 크다. Olga-C 지역의 Zone A 에서는 응력완화효과가 유발되지만, Zone B에서는 응력완화효과가 유발 되지 않았다.

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Anti-anemic Effect of Aqueous Extracts of Fructus schisandrae on Phenylhydrazine-induced Hemolytic Anemia in Female Sprague-Dawley Rats (자성(雌性) 흰쥐에서 phenylhydrazine으로 유발된 용혈성 빈혈에 오미자 약침의 항빈혈효과)

  • Shin Hye-Sook;Kim Ee-Hwa;Kim Chang-Ju
    • Korean Journal of Acupuncture
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    • v.19 no.1
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    • pp.67-75
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    • 2002
  • 목적 : 자성(雌性) 흰쥐에서 phenylhydrazine으로 유발된 용혈성 빈혈에 오미자 약침의 항빈혈효과를 알아보기 위해서 적혈구수, hematocrit ratio, hemoglobin, 혈청 철함유량 및 serum total iron binding capacity (TIBC)를 관찰하였다. 방법 : 실험동물은 정상군, 대조군, 250 mg/kg 오미자 투여군 및 500 mg/kg 오미자 투여군으로 총 4개의 군으로 분류하였다. 정상군의 흰쥐는 아무런 처치도 하지 않았고, 대조군은 phenylhydrazine으로 용혈성 빈혈을 유발하였다. 오미자 투여군은 용혈성 빈혈을 유발한 후 7일간 매일 250 mg/kg 및 500 mg/kg의 용량으로 중완혈에 자침하였다. 결과 : 적혈구수, hematocrit ratio 및 hemoglobin은 대조군에서 정상군에 비해 감소한 반면 오미자 투여군은 증가하였다. 혈청 철함유량과 TIBC는 대조군에서 증가하였으나, 오미자 투여군에서는 감소하였다. 이러한 결과로 중완혈에 오미자 자침은 phenylhydrazine으로 유발된 용혈성 빈혈에서 항빈혈효과가 있는 것으로 사려된다.

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Analysis of Economic Effects of Beauty Industry by Input-Output Table (뷰티산업의 경제적 효과분석 연구)

  • Bae, Ki-Hyung;Lee, Yun-Jin
    • The Journal of the Korea Contents Association
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    • v.13 no.4
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    • pp.350-360
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    • 2013
  • The purpose of this study was to analyze how much the beauty industry contributes to the national economy by measuring economic spreading effects of beauty industry on national economy. To achieve this purpose, the study used the beauty Input-Output Table of year 2009 of korea. The results shows that beauty industry induce 598,453 billion won of national production, especially beauty industry shows that production inducement coefficient is 1.810,Index of the power of dispersion is 0.965, index of the sensitivity of dispersion is 0.534, value-added coefficient is 0.728, and labor inducement coefficient is 0.039. The beauty industry's final demand 11,004 won be put into the national economy, GDP inducement 598,438 one billion won in the beauty industry one billion won 11,029 accounted for 1.8% of the total, and the value-added inducement 4,947 billion(2.3%),tax inducement 23,798.5 billion(3.5 %), income inducement 91,187 billion(2.5%). Regarding the industrial linkage effect, beauty industry has an relatively higher growth potential in the national economy than other the manufacturing industry.