• Journal of the korean academy of Pediatric Dentistry
• /
• v.44 no.3
• /
• pp.298-305
• /
• 2017

This study aimed to compare chair-side test results for caries risk assessment and evaluate how well the tests reflect caries experience. The study was conducted on children aged < 6 years in primary dentition. Dental examination of children was conducted to determine the dmft index and subjects were divided into two groups : group I (dmft < 6), group II (dmft > 6). This study used four kinds of test kits (Plaque-check PH kit, Saliva-check buffer kit, Saliva-check mutans kit, Cytoperio analysis system). Saliva buffer capacity was significantly low in the high caries experience group (dmft > 6) and correlated with dmft index. Saliva pH level correlated significantly with saliva buffer capacity. The results showed that plaque pH and saliva pH levels had no correlation with dmft index. The Streptococcus mutans level measured by using the Saliva-check mutans and Cytoperio analysis system did not correlate with dmft index.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.3
• /
• pp.297-303
• /
• 2018

This study investigated the effect of community-based health intervention program to improve metabolic disease in Jeju island. There were 50 obese local residents in the experimental group (body mass index, $BMI{\geq}25kg/m^2$). They participated in cooking therapy with nutrition education (4 times), exercise program with proprioceptive neuromuscular facilitation (PNF) and stretching training (9 times), and alternative medicine program with healing touch massage (3 times) during a 3-week period. To evaluate the effectiveness of the program, body composition, blood lipid profiles, blood glucose, and waist circumference were assessed before and after the intervention program. After the program, the value of total cholesterol (TC), glycosylated hemoglobin (HbA1C), diastolic blood pressure, percent body fat, and waist circumference were decreased, and became the normal value. Especially, HbA1C, percent body fat, and waist circumference were significantly decreased (P<0.001) in the experimental group, while HbA1C, percent body fat, and waist circumference were significantly increased (P<0.001) in the control group (N=50), who had no intervention. Our results suggest that metabolic syndrome associated markers need intervention program for improving them. In conclusion, although this study did not analyze the effect of the health intervention program and cooking therapy separately, considering the result of this 3-week, short term program, the effect will be more profuse if cooking therapy and exercise program were performed concurrently.

• Korean Journal of Clinical Laboratory Science
• /
• v.51 no.1
• /
• pp.26-33
• /
• 2019

Recently, the rapid growth of the companion animal market has led to the development of animal disease diagnosis kits. Therefore, the utility of the introduction of biomarkers for the development of animal molecular diagnostics is being reevaluated. A good biomarker should be precise and reliable, distinguish between normal and diseased states, and differentiate between different diseases. Recently reported genetic markers, tumor markers (cell free DNA, circulating tumor cells, granzyme, and skin tumors), and others (brucellosis, programmed death recovery-1, symmetric dimethylarginine, periostin, and cysteinyl leukotrien) have been developed. The biomarkers are used for risk prediction or for the screening, diagnosis, and monitoring of disease progression. The most important criteria for related biomarkers are disease specificity. Many potential biomarkers have emerged from laboratory and test studies, but they have not been validated in independent or large-scale clinical studies. Candidate biomarkers evaluate disease associations, verify the effectiveness of biomarkers for early detection and disease progression, and incorporate them into humans and animals. In the future, it will be necessary to reevaluate the utility of well-structured biomarker-based research and study the development of kits that can be used in on-site tests in accordance with the trends introduced in the diagnosis of animal diseases.

• 한국방재학회:학술대회논문집
• /
• 2011.02a
• /
• pp.92-92
• /
• 2011

최근 건설기술의 발전과 함께 강재 케이블을 이용하는 시설물의 시공이 점점 증가하는 추세이다. 특히 현수교, 사장교와 같은 초장대 교량에 사용되는 케이블은 주거더 및 상판에 의한 하중의 대부분을 지지하는 핵심부재이다. 하지만 이러한 케이블 부재는 부식, 파단 등으로 인한 단면손실이 발생할 수 있고, 이로 인한 손상부의 응력집중으로 인해 시설물 전체의 붕괴로 이어질 수 있는 위험성을 가진다. 따라서 조기에 단면손실을 찾아 사고를 미연에 방지할 수 있는 강재 케이블 비파괴 검사 기술기반의 건전성 모니터링이 필수적이다. 이러한 효율적인 건전성 모니터링을 위해 스마트 센서를 활용한 연구가 활발히 이루어지고 있는데, 그중 대표적인 스마트 센서중 하나인 마그네틱 센서는 높은 신뢰도와 어디에나 적용 가능한 재현성 때문에 구조물 건전성 평가에 적용하기 유용한 기술로 그 적용범위가 선박, 항공등으로 점점 넓어지고 있는 추세이다. 마그네틱 센서는 그 적용대상에 따라 다양한 마그네틱 특성을 활용할 수 있는데, 최근에는 투자율 계측을 통해 케이블의 장력 측정이 가능한 Elasto-Magnetic 센서(E/M 센서)가 개발되었고 그 활용성에 대한 연구가 이뤄지고 있다. 이에 본 연구에서는 E/M 센서를 이용한 강재 케이블 모니터링 기술을 제안하고자 한다. E/M 센서는 본래 케이블의 장력측정을 위해 개발되었지만 본 연구에서는 강재 케이블 부재의 단면손실 검색을 위해 적용하였다. 제안된 기술의 실험적 검증을 위해 E/M 센서를 이용하여 4가지의 다른 직경을 가지는 강봉시편을 E/M 센서헤드의 1차 코일을 통해 자화시키고, 각각의 직경에서 출력전압을 2차 코일을 이용하여 계측하였다. 그 결과 강봉의 직경이 감소함에 따라 출력 전압이 감소함을 보였다. 반복실험을 통해 해상도 및 선형성이 확보되는 최적의 입력전압과 출력전압의 워킹포인트를 선정하였고, 선정된 조건에서 강봉시편을 일정 간격으로 스캔한 결과 단면감소에 따른 선형적인 출력전압 감소와 동시에 단면 변화 지점에서는 추세선에서 크게 벗어난 출력전압 계측값을 나타내었다. 본 실험을 통해 제안된 E/M 센서를 이용한 강재 케이블 모니터링 기술의 유용성 및 적용가능성을 확인할 수 있었다.

• Smart Media Journal
• /
• v.1 no.4
• /
• pp.52-58
• /
• 2012

In recent years the combination of IT and BT for U-Healthcare Medical Services has attracted popular attention as an alternative for solving health problems due to aging issue. Active oxygen as free radicals causes unstable state of the body resulting to other disease on which approximate 90% of the diseases are associated with active oxygen. The severity is even higher along with increasing age. Therefore, there is a need for systematic management of active oxygen saturation for the elderly and chronic patients. In this paper, the data about active oxygen measurements from the body measurement is sent to the data storage of medical facilities by the service provider. Medical information is measured by devices provided complying with the standard, support and information using Bluetooth communication. Users can check their health status themselves using the proposed system through 3G/4G mobile devices like smart phone to medical institutions in which the smart phone act as a gateway for medical data transferred from patient to medical institutions and vice versa. Users can get and experience a diagnosis and effective U-Environmental Health Services from Medical institutions anywhere using the proposed built system.

• The KIPS Transactions:PartA
• /
• v.18A no.5
• /
• pp.193-204
• /
• 2011

Since web applications are accessed by anonymous users via web, more security risks are imposed on those applications. In particular, because security vulnerabilities caused by insecure source codes cannot be properly handled by the system-level security system such as the intrusion detection system, it is necessary to eliminate such problems in advance. In this paper, to enhance the security of web applications, we develop a static analyzer for detecting the well-known security vulnerability of PHP file inclusion vulnerability. Using a semantic based static analysis, our vulnerability analyzer guarantees the soundness of the vulnerability detection and imposes no runtime overhead, differently from the other approaches such as the penetration test method and the application firewall method. For this end, our analyzer adopts abstract interpretation framework and uses an abstract analysis domain designed for the detection of the target vulnerability in PHP programs. Thus, our analyzer can efficiently analyze complicated data-flow relations in PHP programs caused by extensive usage of string data. The analysis results can be browsed using a JAVA GUI tool and the memory states and variable values at vulnerable program points can also be checked. To show the correctness and practicability of our analyzer, we analyzed the source codes of open PHP applications using the analyzer. Our experimental results show that our analyzer has practical performance in analysis capability and execution time.

• Journal of agricultural medicine and community health
• /
• v.44 no.1
• /
• pp.1-10
• /
• 2019

Objectives: This study aimed to assess the status of Scrub typhus, Leptospirosis and HFRS(hemorrhagic fever with renal syndrome) among farmers with febrile illness. Methods: We involved a total of 841 farmers who had febrile illness(508 and 333 village residents were, respectively, three and four district of Gyeongju city) selected during autumn of 2014 and 2015. Data were collected by survey questionnaires and blood sample examination. Results: Serum response rate for Scrub typhus and Leptospirosis was 1.5% each and 1.9% for HFRS. Serum response rate for Scrub typhus was significantly higher for tick-bite cases(38.5%), while Leptospirosis was significantly higher for those who were in fruit-planting work(23.1%). Similarly, serum response rate was significantly higher for HFRS who were working in venyl green house work(25.0%). Conclusions: Government authority should develop effective and efficient preventive strategies to create awareness of infectious diseases among farmers. Extending information, education and communication be reached to farmers that could change their perception and help early diagnosis and treatment and reduce the disease burden and its complication.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.4
• /
• pp.391-398
• /
• 2018

Mesenchymal stem cells (MSCs) are an attractive resource for refractory patients because of their anti-inflammatory/immunomodulatory capability and multi-lineage differentiation potential. The transplantation of MSCs has led to positive results in preclinical and clinical application to various diseases, including autoimmune disease, cardiovascular disease, cancer, liver cirrhosis, and ischemic stroke. On the other hand, studies have shown that paracrine factors, not direct cell replacement for damaged cells or tissue, are the main contributors in MSC-based therapy. More recently, evidence has indicated that MSC-derived exosomes play crucial roles in regulating the paracrine factors that can mediate tissue regeneration via transferring nucleic acids, proteins, and lipids to the local microenvironment and cell-to-cell communication. The use of these exosomes is likely to be beneficial for the therapeutic application of MSCs because their use can avoid harmful effects, such as tumor formation involved in cell transplantation. Therefore, therapeutic applications using MSC-derived exosomes might be safe and efficient strategies for regenerative medicine and tissue engineering. This review summarizes the recent advances and provides a comprehensive understanding of the role of MSC-derived exosomes as a therapeutic agent.

• Journal of the Korea Convergence Society
• /
• v.10 no.12
• /
• pp.53-61
• /
• 2019

The risk of project failure has increased recently as ERP systems have been transformed into Web environments and task complexity has increased. Although low-code platform development tools are being used as a way to solve this problem, limitations exist as they are centered on UI. To overcome this, back-end development tools are required that can be developed quickly and easily, not only from the front development but also from a variety of development sources produced from the ERP development process, including back-end business services. In addition, the development tools included within existing ERP products require a lot of learning time from the perspective of beginner and intermediate developers due to high entry barriers. To address these shortcomings, this paper seeks to study ways to overcome the limitations of existing development tools within the ERP by providing customized development tool functions by enhancing the usability of ERP development tools suitable for each developer's skills and roles based on the requirements required by ERP development tools, such as reducing the time required for querying, automatic binding of data for testing for service-based units, and checking of source code quality.

• Journal of Radiation Protection and Research
• /
• v.40 no.2
• /
• pp.118-123
• /
• 2015

The frequency of diagnostic radiation examinations in medical institutions has recently increased to 220 million cases in 2011, and the annual exposure dose per capita was 1.4 mSv, 51% and 35% respectively, compared to those in 2007. The number of chest radiography was found to be 27.59% of them, the highest frequency of normal radiography. In this study, we developed a shielding device to minimize radiation exposure by shielding areas of the body which are unnecessary for image interpretation, during the chest radiography. And in order to verify its usefulness, we also measured the difference in entrance surface dose (ESD) and the absorbed dose, before and after using the device, by using an international standard pediatric (10 years) phantom and a glass dosimeter. In addition, we calculated the effective dose by using a Monte Carlo simulation-based program (PCXMC 2.0.1) and evaluated the reduction ratio indirectly by comparing lifetime attributable risk of cancer incidence (LAR). When using the protective device, the ESD decreased by 86.36% on average, nasal cavity $0.55{\mu}Sv$ (74.06%), thyroid $1.43{\mu}Sv$ (95.15%), oesophagus $6.35{\mu}Sv$ (78.42%) respectively, and the depth dose decreased by 72.30% on average, the cervical spine(upper spine) $1.23{\mu}Sv$ (89.73%), salivary gland $0.5{\mu}Sv$ (92.31%), oesophagus $3.85{\mu}Sv$ (59.39%), thyroid $2.02{\mu}Sv$ (73.53%), thoracic vertebrae(middle spine) $5.68{\mu}Sv$ (54.01%) respectively, so that we could verify the usefulness of the shielding mechanism. In addition, the effective dose decreased by 11.76% from $8.33{\mu}Sv$ to $7.35{\mu}Sv$ before and after wearing the device, and in LAR assessment, we found that thyroid cancer decreased to male 0.14 people (95.12%) and female 0.77 people (95.16%) per one million 10-year old children, and general cancers decreased to male 0.14 people (11.70%) and female 0.25 people (11.70%). Although diagnostic radiation examinations are necessary for healthcare such as the treatment of diseases, based on the ALARA concept, we should strive to optimize medical radiation by using this shielding device actively in the areas of the body unnecessary for the diagnosis.