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Interstitial Vaginal Needle Implantation in Gynecological Tumors : Design and Construction of Applicator (부인과암에서 조직내 삽입 방사선치료 - Applicator의 고안 및 제작-)

  • Kang, Seung-Hee;Chun, Mi-Son;Kang, Hae-Jin;Jung, Chil;Son, Jeong-Hyae
    • Radiation Oncology Journal
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    • v.16 no.2
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    • pp.167-175
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    • 1998
  • Purpose : It is not a simple task to achieve the ideal isodose curve with a standard vaginal applicator or sing1e plane needle impant in the paravaginal tissue when primary or recurrent gynecological neoplasms(cervical cancers, vaginal cancers and vulvar cancers) are treated as a boost following external beam radiotherapy. The authors introduce the development and construction of a simple, inexpensive, customized applicator for volume implant to maximize the radiation dose to the tumor while minimizing the dose to the rectum and the bladder. Materials and Methods : Nine patients underwent Ir-192 transperineal interstitial implantation for either recurrent(5 cases) or primary(3 cases) cervical cancers or primary vaginal cancer(1 case) between August 1994 and February 1998 at Ajou university hospital. First 3 cases were performed with a sing1e plane implant guided by digital palpation. Because of inadequate isodose coverage in the tumor volume in first 3 cases, we designed and constructed interstitial vaginal applicator for volume implant to improve tumor dose distribution and homogeneity while sparing the surrounding normal tissue. Our applicators consist of vaginal obturator and perineal template that made of the clear acrylamide and dental mold material$(Provil^{(R)})$. The applicators were customized individually according to the tumor size and its location Both HDR and LDR irradiation were given with these applicators accomodating 6 Fr needles(Microselectron Nucletron). The pretreatment planning prior to actual implant was performed whenever possible. Results : Needles can be inserted easily and evenly into the tumor volume through the holes of templates, requiring less efforts and time for the implant procedure. Our applicators made of materials available from commercial vendors. These have an advantage that require easy procedure, and spend relatively short time to construct. Also it was possible to fabricate applicators to individualize according to the tumor size and its location and to achieve the ideal isodose coverage. We found an accurate needle arrangement and ideal dose distribution through the CT scan that was obtained in 3 cases after needle implant. Three patients with primary cervical and vaginal cancers were controlled locally at final follow up. But all recurrent cases failed to do so. Conclusion : The authors introduce inexpensive, simple interstitial vaginal templates which were self-designed and constructed using materials available from commercial vendors such as acrylanide and dental mold material $(Provil^{(R)})$.

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Report about First Repeated Sectional Measurements of Water Property in the East Sea using Underwater Glider (수중글라이더를 활용한 동해 최초 연속 물성 단면 관측 보고)

  • GYUCHANG LIM;JONGJIN PARK
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.29 no.1
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    • pp.56-76
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    • 2024
  • We for the first time made a successful longest continuous sectional observation in the East Sea by an underwater glider during 95 days from September 18 to December 21 2020 in the Korea along the 106 Line (129.1 °E ~ 131.5 °E at 37.9 °N) of the regular shipboard measurements by the National Institute of Fishery Science (NIFS) and obtained twelve hydrographic sections with high spatiotemporal resolution. The glider was deployed at 129.1 °E in September 18 and conducted 88-days flight from September 19 to December 15 2020, yielding twelve hydrographic sections, and then recovered at 129.2 °E in December 21 after the last 6 days virtual mooring operation. During the total traveled distance of 2550 km, the estimated deviation from the predetermined zonal path had an average RMS distance of 262 m. Based on these high-resolution long-term glider measurements, we conducted a comparative study with the bi-monthly NIFS measurements in terms of spatial and temporal resolutions, and found distinguished features. One is that spatial features of sub-mesoscale such as sub-mesoscale frontal structure and intensified thermocline were detected only in the glider measurements, mainly due to glider's high spatial resolution. The other is the detection of intramonthly variations from the weekly time series of temperature and salinity, which were extracted from glider's continuous sections. Lastly, there were deviations and bias in measurements from both platforms. We argued these deviations in terms of the time scale of variation, the spatial scale of fixed-point observation, and the calibration status of CTD devices of both platforms.

Sputtering방식을 이용한 Indium Thin oxide박막의 넓이에 따른 X-ray 검출기 특성 연구

  • Kim, Dae-Guk;Sin, Jeong-Uk;O, Gyeong-Min;Kim, Seong-Heon;Lee, Yeong-Gyu;Jo, Seong-Ho;Nam, Sang-Hui
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.321-322
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    • 2012
  • 의료용 방사선 장비는 초기의 아날로그 방식의 필름 및 카세트에서 진보되어 현재는 디지털 방식의 DR (Digital Radiography)이 널리 사용되며 그에 관한 연구개발이 활발히 진행되고 있다. DR은 크게 간접방식과 직접방식의 두 분류로 나눌 수 있는데, 간접방식은 X선을 흡수하면 가시광선으로 전환하는 형광체(Scintillator)를 사용하여 X선을 가시광선으로 전환하고, 이를 Photodiode와 같은 광소자로 전기적 신호로 변환하여 방사선을 검출하는 방식을 말하며, 직접 방식은 X선을 흡수하면 전기적 신호를 발생 시키는 광도전체(Photoconductor)를 사용하여 광도전체 양단 전극에 고전압을 인가한 형태를 취하고 있는 가운데, X선이 조사되면 일차적으로 광도전체 내부에서 전자-전공쌍(Electron-hole pair)이 생성된다. 이들은 광도전체 양단의 인가되어 있는 전기장에 의해 전자는 +극으로, 전공은 -극으로 이동하여 아래에 위치한 Active matrix array을 통해 방사선을 검출하는 방식이다. 본 연구에서는 직접방식 X-ray 검출기에서 활용되는 a-Se을 ITO (Indium Thin oxide) glass 상단에 Thermal evaporation증착을 이용하여 두께 $50{\mu}m$, 33 넓이로 증착 시킨 다음, a-Se상단에 Sputtering증착을 이용하여 ITO를 11 cm, 22 cm, $2.7{\times}2.7cm$ 넓이로 증착시켜 상하부의 ITO를 Electrode로 이용하여 직접방식의 X-ray검출기 샘플을 제작하였다. 제작 과정 중 a-Se의 Thermal evaporation증착 시, 저진공 $310^{-3}_{Torr}$, 고진공 $2.210^{-5}_{Torr}$에서 보트의 가열 온도를 두 번의 스텝으로 나누어 증착 시켰다. 첫 번째 스텝 $250^{\circ}C$, 두 번째 스텝은 $260^{\circ}C$의 조건으로 증착하여 보트 내의 a-Se을 남기지 않고 전량을 소모할 수 있었으며, 스텝간의 온도차를 $10^{\circ}C$로 제어하여 균일한 박막을 형성 할 수 있었다. Sputtering증착 시, 저진공 $2.510^{-3}$, 고진공 $310^{-5}$에서 Ar, $O_2$를 사용하여 100 Sec간 플라즈마를 생성시켜 ITO를 증착하였다. 제작된 방사선 각각의 검출기 샘플 양단의 ITO에 500V의 전압을 인가하고, 진단 방사선 범위의 70 kVp, 100 mA, 0.03 sec 조건으로 X-ray를 조사시켜 ITO넓이에 따른 민감도(Sensitivity)와 암전류(Dark current)를 측정하였다. 측정결과 민감도(Sensitivity)는 X-ray샘플의 두께에 따른 $1V/{\mu}m$ 기준 시, 증착된 ITO의 넓이가 11 cm부터 22 cm, $2.7{\times}2.7cm$까지 각각 $7.610nC/cm^2$, $8.169nC/cm^2$, $6.769nC/cm^2$로 22 cm 넓이의 샘플이 가장 높은 민감도를 나타내었으나, 암전류(Dark current)는 $1.68nA/cm^2$, $3.132nA/cm^2$, $5.117nA/cm^2$로 11 cm 넓이의 샘플이 가장 낮은 값을 나타내었다. 이러한 데이터를 SNR (Signal to Noise Ratio)로 합산 하였을 시 104.359 ($1{\times}1$), 60.376($2{\times}2$), 30.621 ($2.7{\times}2.7$)로 11 cm 샘플이 신호 대 별 가장 우수한 효율을 나타냄을 알 수 있었다. 따라서 ITO박막의 면적이 클수록 민감도는 우수하나 그에 따른 암전류의 증가로 효율이 떨어짐을 검증 할 수 있었으며, 이는 ITO면적이 넓어짐에 따른 저항의 증가로 암전류에 영향을 끼침을 할 수 있었다. 본 연구를 통해 a-Se의 ITO 박막 면적에 따른 전기적 특성을 검증할 수 있었다.

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Effect of Human Implantable Medical Devices on Dose and Image Quality during Chest Radiography using Automatic Exposure Control (자동노출제어를 적용한 흉부 방사선 검사 시 인체 이식형 의료기기가 선량과 화질에 미치는 영향)

  • Kang-Min Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.3
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    • pp.257-265
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    • 2024
  • In this study, we applied AEC(Auto Exposure Control), which is used in many chest examinations, to evaluate whether medical devices inserted into the body affect the dose and image quality of chest images. After attaching three HIMD(Human implantable medical devices) to the ion chamber, the Monte Carlo methodology-based program PCXMC(PC Program for X-ray Monte Carlo) 2.0 was applied to measure the effective dose by inputting the DAP(Dose Ares Product) value derived from the Pacemaker and CRT and Chemoport Additionally, to evaluate image quality, we set three regions of interest and one noise region on the chest and measured SNR and CNR. The final study results showed significant differences in DAP and Effective dose. There was a significant difference between Pacemaker and CRT when AEC was applied and not applied. (p<0.05) When applied, the dose increased by 37% for Pacemaekr and 52% for CRT. Chemoport showed a 10% increase in effective dose depending on whether AEC was applied, but there was no significant difference. (p>0.05) In the image quality evaluation, there was no significant difference in image quality between all HIMD insertions and AEC applied or not. (p>0.05) Therefore, when the HIMD was inserted into the chest during a chest x ray and overlapped with the ion chamber sensor, the effective dose increased, and there was no difference in image quality even at a low dose without AEC. Therefore, when performing a chest X-ray examination of a patient with a HIMD inserted, it is considered that performing the examination without applying AEC is a method that can be considered to reduce the patient's radiation exposure.

A Dynamic Queue Manager for Optimizing the Resource and Performance of Mass-call based IN Services in Joint Wired and Wireless Networks (유무선 통합 망에서 대량호 지능망 서비스의 성능 및 자원 최적화를 위한 동적 큐 관리자)

  • 최한옥;안순신
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.5B
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    • pp.942-955
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    • 2000
  • This paper proposes enhanced designs of global service logic and information flow for the mass-call based IN service, which increase call completion rates and optimize the resource in joint wired and wireless networks. In order to hanve this logic implemented, we design a Dynamic Queue Manager(DQM) applied to the call queuing service feature in the Service Control Point(SCP). In order to apply this logic to wireless service subscribers as well as wired service subscribers, the service registration flags between the Home Location Register(HLR) and the SCP are managed to notify the DQM of the corresponding service subscribers’ mobility. Hence, we present a dynamic queue management mechanism, which dynamically manages the service group and the queue size based on M/M/c/K queueing model as the wireless subscribers roam the service groups due to their mobility characteristics. In order to determine the queue size allocated by the DQM, we simulator and analyze the relationship between the number of the subscriber’s terminals and the drop rate by considering the service increment rate. The appropriate waiting time in the queue as required is simulated according to the above relationship. Moreover, we design and implement the DQM that includes internal service logic interacting with SIBs(Service Independent building Blocks) and its data structure.

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A Study on the Numerical Modeling of the Fish Behabior to the Model Net - Parameter Estimation in Numerical Model of Fish Behavior - (모형그물에 대한 어군행동의 수직 모델링에 관한 연구 - 어군행동을 나타내는 수치 모델의 파라메터 추정 -)

  • Lee, Byoung-Gee;Lee, Dae-Jae;Chang, Ho-Young
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.4
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    • pp.307-325
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    • 1995
  • IN order to gain a fundamental data for forecast or control of fish behavior and evaluated the feasibility of an application of the modeling technique to a field, in this paper a numerical model for describing the behavior of fishes in a water tank was presented. The parameters of the model were estimated by using the time-series data on the three-dimensional position of fishes and by applying the least squares algorithm. The estimated parameters were standardized to examine the variation of parameters according to the number of individuals and flow speed that the mean values of parameters were to be zero and their variances were to be one. The results obtained can be summarized as follows: (1) The standardized parameter $a^*$of propulsive force decreased according to increased the number of individuals and the flow speed. (2) The standardized parameter ${k_b}^*$ of interactive force increased according to increased the number of individuals, but decreased according to the flow speed. (3) The standardized parameter ${k_c}^*$ of schooling force increased according to │increased the number of individuals and the flow speed. (4) The standardized parameter │${k_w}^{+*}$│ of repulsive force against wall or bottom increased according to increased the number of individuals, but decreased according to the flow speed. (5) The standardized parameter │${k_w}^{-*}$│ of attractive force against wall or bottom was generally constant according to increased the number of individuals, but increased according to the flow speed. (6) The standardized parameter $\upsilon$ super(*) of damping force increased according to increased the number of individuals, but decreased according to the flow speed.

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Numerical Analysis of CO2 Behavior in the Subsea Pipeline, Topside and Wellbore With Reservoir Pressure Increase over the Injection Period (시간 경과에 따른 저류층 압력 상승이 파이프라인, 탑사이드 및 주입정 내 CO2 거동에 미치는 영향에 대한 수치해석적 연구)

  • Min, Il Hong;Huh, Cheol;Choe, Yun Seon;Kim, Hyeon Uk;Cho, Meang Ik;Kang, Seong Gil
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.19 no.4
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    • pp.286-296
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    • 2016
  • Offshore CCS technology is to transport and inject $CO_2$ which is captured from the power plant into the saline aquifer or depleted oil-gas fields. The more accumulated injected $CO_2$, the higher reservoir pressure increases. The increment of reservoir pressure make a dramatic change of the operating conditions of transport and injection systems. Therefore, it is necessary to carefully analyze the effect of operating condition variations over the injection period in early design phase. The objective of this study is to simulate and analyze the $CO_2$ behavior in the transport and injection systems over the injection period. The storage reservoir is assumed to be gas field in the East Sea continental shelf. The whole systems were consisted of subsea pipeline, riser, topside and wellbore. Modeling and numerical analysis were carried out using OLGA 2014.1. During the 10 years injection period, the change of temperature, pressure and phase of $CO_2$ in subsea pipelines, riser, topside and wellbore were carefully analyzed. Finally, some design guidelines about compressor at inlet of subsea pipeline, heat exchanger on topside and wellhead control were proposed.

Development and Thermal Distribution of An RF Capacitive Heating Device (유전가열장치의 개발과 온열분포)

  • Chu, Sung-Sil;Suh, Chang-Ok;Kim, Gwi-Eon;Loh, John-Kyu;Kim, Byung-Soo
    • Radiation Oncology Journal
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    • v.5 no.1
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    • pp.49-58
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    • 1987
  • Hypertermia for the treatment of cancer has been introduced for a long time and the biological effect for the use of hyperthermia to treat malignant tumors has been well established and encouraging clinical results have been obserbed. Unfortunately, however, the engineering or technical aspects of hyperthermia for the deep seated tumors has not been satisfactory. We developed the radiofrequency capactive hyperthermia device (Greenytherm-GY8) in cooperation with Yonsei Cancer Center and Green Cross Medical Corporation. It was composed with $8{\sim}10MHz$ RF generator, capacitive electrode, matching system, cooling system, temperature measuring system and control PC computer. The thermal profile was investigated in agar phantom, animals and in human tumors, heated with capactivie RF device. Deep and homogeneous heating could be achieved in a large phantom of 25cm diameter and 19cm thick when heated with a pair of 23cm diameter electrodes, coupled to both bases of the phantom, when the size of the two electrodes was not the same, the region near the smaller electrode was preferentially heated. It was, therefore, possible to control the depth of heating by choosing proper size of electrodes. Therapeutic temperature $(42^{\circ}C{\sim}43^{\circ}C)$ could be obtained in the living animal experiments. Indications are that deep heating of humn tumors might be achieved with the capacitive method, provided that subcutaenous fat layer is cooled by temperature controlled bolus and large size of electrodes.

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Fabrication of IMT-2000 Linear Power Amplifier using Current Control Adaptation Method in Signal Cancelling Loop (신호 제거 궤환부의 전류 제어 적응형 알고리즘을 이용한 IMT-2000용 선형화 증폭기 제작)

  • 오인열;이창희;정기혁;조진용;라극한
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.40 no.1
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    • pp.24-36
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    • 2003
  • The digital mobile communication will be developed till getting multimedia service in anyone, any where, any time. Theses requiring items are going to be come true via IMT-2000 system. Transmitting signal bandwidth of IMT-2000 system is 3 times as large as IS-95 system. That is mean peak to average of signal is higher than IS-95A system. So we have to design it carefully not to effect in adjacent channel. HPA(High Power Amplifier) located in the end point of system is operated in 1-㏈ compression point(Pl㏈), then it generates 3rd and 5th inter modulation signals. Theses signals affect at adjacent channel and RF signal is distorted by compressed signal which is operated near by Pl㏈ point. Then the most important design factor is how we make HPA having high linearity. Feedback, Pre-distorter and Feed-forward methods are presented to solve theses problems. Feed-forward of these methods is having excellent improving capacity, but composed with complex structure. Generally, Linearity and Efficiency in power amplifier operate in the contrary, then it is difficult for us to find optimal operating point. In this paper we applied algorithm which searches optimal point of linear characteristics, which is key in Power Amplifier, using minimum current point of error amplifier in 1st loop. And we made 2nd loop compose with new structure. We confirmed fabricated LPA is operated by having high linearity and minimum current condition with ACPR of -26 ㏈m max. @ 30㎑ BW in 3.515㎒ and ACLR of 48 ㏈c max@${\pm}$㎒ from 1W to 40W.

Improvement of Microwave Water Surface Current Meter and its Commercialization (전자파표면유속계의 성능개선 및 실용화)

  • Kim, Young-Sung;Lee, Hyun-Seok
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.85-85
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    • 2011
  • 홍수기에 안전하고 정확한 유량측정을 통하여 물관리에 필요한 기초수문자료를 확보하고자 한국수자원공사에서 1993년도부터 홍수유량측정기술 확보를 위한 연구를 시작하였다. 그간의 연구성과를 바탕으로 1999년도에 하천의 유속을 비접촉식으로 측정할 수 있는 홍수용 전자파표면유속계를 개발하여 특허등록하였고 그와 동시에 이의 상품화를 추진하여 2010년도까지 75대를 보급하여 실무에서 이용하고 있다. 이동식인 홍수용 전자파표면유속계를 바탕으로 2001년도에는 고정식 실시간 홍수유량측정측정시스템을 개발하여 특허등록하였고, 이 시제품을 현재 용담 수자원시험유역의 동향지점에서 시험운영하고 있다. 또한, 현장 유량측정실무자들의 홍수용 전자파표면유속계 개선요구에 따라 편각용 전자파표면유속계 시제품을 개발하였으며, 이는 임의의 한 지점에 설치한 한 대의 장비로 좌우 여러 측선의 유속을 동시에 측정할 수 있는 다점 측정기능을 갖도록 성능을 개선하였다. 이에 따라 홍수시 유량측정에 소요되는 시간이 줄어들어 신속하게 유량측정을 완료할 수 있는 계기를 마련하였다. 이와 더불어 유속측정 범위를 확장하여 홍수시의 고유속 뿐만 아니라 0.5 m/s 이하의 저유속까지 측정할 수 있는 범용 전자파표면유속계의 시제품을 추가로 개발하였다. 이 장비는 최저유속 0.03 m/s의 측정을 실내시험을 통하여 입증하였다. 범용 전자파표면유속계는 상품화 시제품의 개발을 목표로 기존 시제품의 현장시험을 통하여 현장적용상의 문제점에 대한 해결에 주력하였다. 첫째, 평갈수용 전자파표면유속계의 사용편의를 개선하기 위하여 소형화 및 경량화를 추진하였고, 이를 위하여 사용주파수를 기존의 10 GHz에서 24 GHz로 변경함으로써 $35{\times}35\;cm$ 크기의 기존안테나를 $22{\times}22\;cm$ 크기로 소형화하였으며 송수신부의 무게는 기존 18 kg에서 3.3 kg으로 혁신적으로 줄이는데 성공하였다. 이를 위하여 안테나는 기존의 반사형안테나에서 도파관슬롯배열안테나로 변경하였다. 둘째, 측정값의 안정화를 위하여 안테나의 특성을 개선하여 부엽(side-lobe) 레벨 30 dB 이하 그리고 전후방비(front-back ratio) 50 dB 이하로 개선하여 안테나가 지향하는 방향 이외의 위치에서 반사되는 불필요한 신호를 줄였다. 또한 적응형 이득제어(adaptive gain control)기법의 채택으로 미소 신호에 대한 안정적 측정 및 과다 신호에 대한 능동적 감쇄를 할 수 있도록 시스템을 구성하여 전 유속범위에 대한 안정적 측정을 가능토록 설계 및 제작하였다. 셋째, 자가점검 기능을 탑재하여 유속측정 전에 기기의 상태에 대한 self test기능을 통하여 측정자가 기기의 상태를 사전에 파악 가능토록함으로써, 기기 오작동에 대한 능동 대처할 수 있도록 하였다. 이외에도 저전력 회로설계를 통하여 배터리 사용시간을 확장하였고, 기존의 전자파표면유속계가 가지고 있던 방습 및 방수에도 내성을 갖는 제품으로 설계하였으며 스마트기기를 이용한 무선측정 및 세련된 디자인 등 사용자의 요구사항을 충분히 반영하였다.

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