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Wireless capsule endoscopy Locomotion

  • Wang, Zhao;Lim, Eng Gee;Leach, Mark;Xia, Tianqi;Lee, Sanghyuk
    • Journal of Convergence Society for SMB
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    • v.4 no.1
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    • pp.55-62
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    • 2014
  • Wireless capsule endoscopy (WCE) was one of the most influential bio-medical electronic technologies to be developed at the beginning of the century. In comparison to traditional endoscopic diagnosis, this application is characterized as non-invasive and low-risk, thereby providing surgeons with a new alternative for inspecting the entire gastrointestinal (GI) track in a much more user friendly way. Apart from regular hardware upgrades, the frontier of WCE research basically lies in the miniaturization of the capsule and in active locomotion. In order to overcome the intrinsic drawback of current commercialized WCE products, which is that locomotion is generally a function of natural peristalsis, active locomotion is proposed as a series of strategies used to effectively navigate the device into different organs and conduct therapeutic functions within targeted human tissues. Reviews of several novel designs with respect to this aspect of research will be discussed in this article.

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The Relationship between Allergic Diseases and Functional Gastrointestinal Disorders in Children and Adolescents (소아·청소년의 알레르기 질환 (천식, 알레르기비염, 아토피피부염)과 기능성 위장관 질환과의 관계 (단면 조사 연구))

  • Kim, Min Joo;Kim, Deog Gon;Lee, Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.28 no.1
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    • pp.32-42
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    • 2014
  • Objectives The purpose of this study is to establish relationship between allergic diseases and functional gastrointestinal disorders in children and adolescents using objective criteria and questionnaires. Methods This study surveyed 237 children and adolescents who visited the department of Pediatrics of ${\bigcirc}{\bigcirc}$ Korean Medicine Hospital from September 23rd, 2013 to December 26th, 2013. The Korean version of International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and the Korean-translated Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III) were used. We analyzed the data by using PASW Statistics 18.0 with Chi-square test, Fisher's exact test and Linear by linear association. Results There was no significant difference between prevalence of allergic diseases and functional gastrointestinal disorders. Also, there was no strong relationship between the number of allergic diseases and the functional gastrointestinal disorders. However, some parts showed significant relationships - such as asthma symptoms ever and belch; asthma symptoms last 12 months and belch; allergic rhinitis diagnosis ever and belly aches and abdominal pain around and below the belly button; allergic rhinitis treatment last 12 months and belly aches and abdominal pain around and below the belly button; and atopic dermatitis diagnosis ever and irritable bowel syndrome (respectively; p=0.046, p=0.008, p=0.004, p=0.029, p=0.035). And as the number of allergic diseases increases, the prevalence of functional gastrointestinal disorders are 19.4%, 31.3%, 41.7%, 31.0% respectively. Conclusions Although there was no significant relationship between allergic diseases and functional gastrointestinal disorders, some gastrointestinal symptoms were related to allergic diseases.

Growth Rate and Antimicrobial Activity of Lactobacillus plantarum Reacting with Bacterial Culture Supernatant (세균 배양액과 반응한 Lactobacillus plantarum의 생장속도 및 항균 활성에 대한 연구)

  • Ha, Eun-Mi
    • Microbiology and Biotechnology Letters
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    • v.43 no.3
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    • pp.187-194
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    • 2015
  • In this study, L. plantarum, when reacting with the culture media of potential pathogenic bacteria, exhibited an increase in growth rate and antimicrobial activity. In order to examine the characteristics and the nature of the reaction with the bacteria, this study carried out experiments involving culturing the test bacteria in M9 minimal media. Subsequently, the supernatant was incrassated by the decompression-drying method. Through colony forming unit assay, it was confirmed that L. plantarum had the function of growth inhibition to various bacteria. After culturing L. plantarum with bacterial media, the growth rate of L. plantarum was measured by absorbance (OD600), the results showed that the growth rate (E. coli treatment group: OD600 = 0.848, S. typhimurium treatment group: OD600 = 0.848) increased, as compared with the non-treated control group (OD600 = 0.48). In contrast, the concentrate itself did not induce the growth of L. plantarum. These results were observed as a universal phenomenon of the Lactobacillus species. Moreover, the increase in antimicrobial activity was observed in L. plantarum, which reacted with the culture media of E. coli and S. typhimurium, through a disc diffusion assay, and the result of growth inhibition against various bacteria was induced. Finally, based on the analysis results of the characteristics of bacteria culture media, which increased the growth rate of L. plantarum and antibacterial activity, the bacterial media had a tolerance for catabolic enzymes, pH 2−8 and heat. Therefore, this substance can be said to be a small molecule which is highly stable under various conditions.

A Study on the personal protection system for North Korean refugees in South Korea (북한이탈주민 신변보호 체계에 관한 연구)

  • Song, Eun-Hee;Sul, Jin-Bae;Jang, Myung-Sun
    • Korea and Global Affairs
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    • v.2 no.2
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    • pp.63-88
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    • 2018
  • The purpose of the present paper is to examine the North Korean refugee protection system and its shortcomings. Based on the findings from the analysis of legal system and status of personal protection, this paper proposes the following measures to solve the problems and improve South Korea's existing system. First of all, personal protection for North Korean refugees should be carried out in an inclusive and humanitarian manner. Secondly, the collaborative governance operating system for protecting North Korean refugees should be established. Lastly, clear guidelines for personal protection procedures should be developed to ensure personal protection officers'accountability.

Vulnerabilities Analysis of the OTP Implemented on a PC (PC에 탑재된 OTP의 취약점 분석)

  • Hong, Woo-Chan;Lee, Kwang-Woo;Kim, Seung-Joo;Won, Dong-Ho
    • The KIPS Transactions:PartC
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    • v.17C no.4
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    • pp.361-370
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    • 2010
  • OTP(One Time Password) is a user authentication using secure mechanism to authenticate each other in a way to generate a password, an attacker could intercept the password to masquerade as legitimate users is a way to prevent attacks. The OTP can be implemented as H/W or S/W. Token and card type OTP, implemented as H/W, is difficult to popularize because of having problem with deployment and usability. As a way to replace it implemented as S/W on Mobile or PC is introduced. However, S/W products can be target of malicious attacks if S/W products have vulnerability of implementation. In fact, FSA said the OTP implemented on a mobile have vulnerability of implementation. However, the OTP implemented on a PC have no case about analysis of vulnerability. So, in this paper derive security review and vulnerabilities analysis of implemented on a PC.

General Pharmacology of DWP 302, a New Combined Drug for Gastroduodenal Diseases (위장질환 치료용 의약조성물(BWP 302)의 일반약리작용)

  • 임승욱;염제호;김영만;장병수;남권호;김동오;유영효;박명환
    • Biomolecules & Therapeutics
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    • v.1 no.2
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    • pp.211-219
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    • 1993
  • The general and some pharmacological actions of DWP 302 were investigated in animals and the following results were obtained. In central nervous system, DWP 302 had no effects on the pentobarbital induced anaesthesia, locomotor activity, rotarod test, traction test, analgesic action in the mice and body temperature in the rat. DWP 302 showed no depressive action on the convulsion induced by strychnine and electronic shock. From these results, DWP 302 was considered to have no or little pharmacological effect on the central nervous system. Furthermore, DWP 302 had no influences on the normal blood pressure and heart rate. In the isolated ileum of guinea pig, DWP 302 showed neither contractive nor relaxing effects against the acetylcholine ($10^{-6}g/mι$), histamine ($10^{-6}g/mι$) and $BaCl_2$ ($10^{-4}g/mι$) at a concentration of $1.9{\times}10^{-4}g/mι$ in bath. But it caused a slight increase in basal tone at a concentration of $6.3{\times}10^{-4}g/mι$ and this effect was inhibited by atropine $10^{-7}g/mι.$ In the isolated trachea and vas deference, DWP 302 showed no effect on the contractions produced by histamine and norepinephrine, respectively. And DWP 302 showed no effect on the contractions produced by acetylcholine and oxytocin in the isolated nonpregnant rat uterus. DWP 302 had no effect on bile excretion, urine volume, pH and gastrointestinal motility, But, DWP 302 showed a significant inhibitory effect on gastric secretion in the rat.

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Analysis of Healthcare Personnel's Clinical Beliefs and Knowledge behind Overutilization of Stress Ulcer Prophylaxis in Hospitalized Patients (스트레스성 위장궤양 예방치료제 처방남용에 대한 의료전문가의 인식과 지식 분석)

  • Noh, Yoojin;Lee, Jae Myeong;Shin, Sooyoung
    • Korean Journal of Clinical Pharmacy
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    • v.25 no.4
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    • pp.264-272
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    • 2015
  • Background: The over-prescription of acid-suppressive therapy for the provision of stress ulcer prophylaxis (SUP) in hospitalized patients has been identified in a proceeding study. Objective: This study was conducted to evaluate clinicians' beliefs, knowledge and other factors that influence the over-prescribing of SUP in low-risk, non-intensive care unit (non-ICU) patients. Method: A cross-sectional survey consisting of multiple-choice queries and close-ended questions was distributed to healthcare personnel at a major teaching hospital in Korea. Results: More than half of total respondents reported that they would continue SUP following patients discharge from the ICU (77.8%, 43.5%, and 39.7% in the physician, pharmacist, and nurse groups, respectively). Over 55% of physicians would also initiate non-ICU patients on SUP upon hospital admission, and 42.6% of physicians would even continue prophylaxis post hospital discharge. The mean knowledge score regarding SUP indications and side effects was higher in pharmacists compared to physicians and nurses (12.44, 7.40, and 7.28, respectively; p<0.001). High-prescribing behavior was associated with a prescriber's belief that SUP is effective for preventing bleeding (odds ratio 7.40; 95% confidence interval 1.57 to 31.94; p=0.012). Low knowledge score and computerized order set also showed statistically significant association with the overutilization of SUP.

Prevention and management of foreign body ingestion and aspiration during the dental treatment (치과 치료에서 발생하는 이물질의 삼킴과 흡인의 예방과 대처)

  • Jeon, Han-Sol;Lee, Jin-Han
    • Journal of Dental Rehabilitation and Applied Science
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    • v.34 no.2
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    • pp.63-71
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    • 2018
  • Prosthetic restorations through implants were popularized, and they became routine treatments. Small accessories used in the implant prosthodontic procedure are more likely to slip or fall off the dentist's hands. If the dental appliance or material passes into the upper gastrointestinal tract, there is a high possibility of excretion to the outside of the body without complications, but serious complications may occur depending on the type of foreign body. If the foreign body is passed to the airway, it is an emergency situation, and if it is not done properly, it can be fatal. The purpose of this review report is to investigate the process of foreign body ingestion or aspiration during dental treatment, and the method of prevention and treatment.

Literature Review of Postoperative Delirium in Geriatric Patients After Elective Gastrointestinal Cancer Surgery

  • Park, Da-In;Choi-Kwon, Smi
    • Journal of Korean Biological Nursing Science
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    • v.20 no.3
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    • pp.177-186
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    • 2018
  • Purpose: Increasing number of older adults are receiving cancer surgeries especially for gastrointestinal cancers, which brings forth attention to age-related postoperative complication prevention. Postoperative delirium (POD) is a common complication that rises after surgical procedures involving general anesthesia, largely in the elderly population. Due to its sudden onset and fluctuating symptoms, POD often goes underdiagnosed and undertreated even though it may lead to various adverse outcomes. POD in GI cancer surgical elderly patients is poorly understood in terms of prevalence, pathophysiology, assessment, treatment and nursing management. We aimed to identify available literature and investigate study results to broaden our understanding of geriatric GI cancer POD. Methods: The search process involved six databases to identify relevant studies abided by inclusion criteria. Results: Eleven studies were selected for this review. Geriatric POD is closely related to frailty and surgical complications. Frailty increases vulnerability to surgical stress and causes cerebral changes that affect stress-regulating neurotransmitter proportions, brain blood flow, vascular density, neuron cell life and intracellular signal transductions. These conditions of frailty result in increased risks of surgical complications such as blood loss, cardiovascular events and inflammation, which all may lead to the POD. Mini Metal State Examination (MMSE), Confusion Assessment Method (CAM) and Delirium Rating Scale-revised-98 (DRS-R-98) are recommended for POD assessment to identify high-risk patients. Conclusion: The POD prevalence ranged from 8.2% to 51.0%. The multifactorial causative mechanism suggests nurses to identify highrisk elderly GI-cancer surgical patients by reviewing patient-specific factors and surgery-specific factors.

협력관계(協力關係) 구축(構築)에 있어서의 신뢰(信賴)의 역할(役割) : 남북한(南北韓) 관계(關係)를 중심으로

  • An, Seok-Hwan;Im, Won-Hyeok
    • KDI Journal of Economic Policy
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    • v.19 no.1
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    • pp.105-149
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    • 1997
  • 이 논문에서는 남북한 관계를 중심으로 분쟁해소와 협력관계 구축에 있어서 신뢰(信賴)가 할 수 있는 역할(役割)에 대해 검토해 보았다. 이 논문의 모델은 Kreps-Wilson(1982)의 신규진입 게임을 협력관계 구축이라는 새로운 상황에 맞게 변환시킨 순차적 게임모델로서 유한반복(有限反復) 게임구도와 비대칭적(非對稱的) 정보소유(情報所有)를 그 근간으로 한다. 북한이 남한정부가 진보적이라고 믿는 확률을 남한에 대한 '신뢰(信賴)'라고 정의할 때, 신뢰는 크게 나누어 다음과 같은 역할을 한다. 북한이 남한에 대해 작은 규모의 신뢰감만 가지고 있어도 피의자(被疑者)의 딜레마 (Prisoner's Dilemma) 상황을 피할 수 있으며 상당한 기간동안 남북협력관계(南北協力關係)가 지속될 수 있다. 왜냐하면 보수적 성향의 남한정부도 북한이 개혁정책을 추진할 때 대북(對北) 압박정책 대신 포용정책(包容政策)을 통해 얻을 수 있는 수익이 적지 않은 점을 고려하여 상당기간동안 포용정책을 선택할 동기가 있기 때문이다. 하지만 이와 같이 자신의 성향을 은폐하는 위장행동의 가능성이 높은 동안 신뢰(信賴)는 쉽게 증진되지 않는다. 다만 남북한이 협력을 통해 실질적인 수익을 얻을 수 있을 뿐이다. 남북협력관계를 구축하기 위해 남한이 할 수 있는 일은 정책대응에 소요되는 시간을 줄이는 한편, 개혁정책을 통해 북한이 얻을 수 있는 기대수익(期待收益)을 늘리고 남한에 배신당할 경우 입는 피해를 줄여주는 것이다. 특히 장기적인 관점에서 북한의 기대수익을 점진적으로 늘려 '신뢰도(信賴度)가 넘어야 할 문턱'을 낮추는 것이 효과적인 정책이다. 따라서 남북관계를 진전시키기 위해서는 북한의 지속적인 개혁을 조건으로 북한의 기대수익이 점진적으로 증가하는 KEDO식의 장기적 경협사업(經協事業)을 고안하여 추진해야 한다. 이에 반해 인도주의적 명분하에 일과성의 식량지원을 북한에 제공하는 것은 북한의 구조적(構造的) 경제난(經濟難) 해소나 남북관계의 지속적 진전에 별 도움이 안되는 정책이다. 북한은 북한 나름대로 남한을 한번 믿어볼 필요가 있다. 왜냐하면 상대방에 대한 불신(不信)은 결국 협력관계가 유지될 수 있는 기간을 감축시켜 비효율적인 결과를 초래하기 때문이다.

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