• Journal of Gastric Cancer
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• v.8 no.4
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• pp.250-255
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• 2008

Purpose: The purpose of this study was to assess the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for detecting the lymph node (LN) metastasis of gastric cancer. Materials and Methods: 119 patients (M : F=89 : 30; mean age: 64) with gastric cancer were referred for preoperative FDG-PET/CT scanning and spiral enhanced abdominal pelvic CT from June 2006 to July 2008, and these were the subjects of our study. All the patients underwent curative radical gastrectomy and lymph node dissection. A final diagnosis was made for all the patients by the histology of the surgical specimens. Results: Both PET/CT and enhanced CT showed similar sensitivity for detecting regional lymph node metastasis (32.6% vs 39.5%, respectively). PET/CT was more accurate than enhanced CT for detecting regional lymph node metastasis (67.2% vs 63.0%, respectively), and PET/CT showed better specificity (86.8% vs 76.3, respectively) and a better positive predictive value (PPV) (58.3% vs 48.6%, respectively). PET/CT showed better specificity (98.0% vs 88.2%, respectively) and accuracy (79.4% vs 73.9%, respectively) than enhanced CT for detecting early gastric cancer. PET/CT showed better specificity (64.0% vs 52.0%, respectively), a better PPV (60.9% vs 57.1%), a better negative predictive value (NPV) (48.5% vs 46.4%, respectively) and better accuracy (53.6% vs 51.8%, respectively) than enhanced CT for detecting advanced gastric cancer. Conclusion: FDG-PET/CT is more usefulness than enhanced CT for making the preoperative diagnosis of regional LN metastases from gastric cancers.

• Proceedings of the IEEK Conference
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• 2000.09a
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• pp.135-138
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• 2000

본 논문에서는 DSP Group사의 16 비트 고정 소수점 DSP인 OaKDSP Core를 사용하여 유럽의 이동통신에서 표준으로 사용되고 있는 음성 부호화기 알고리즘인 GSM-EFR (Global System for Mobile communications -Enhanced Full Rate) 을 실시간으로 구현하였다. 구현된GSM-EFR 음성 부호화기의 계산량은 약 24 MIPS가 소요되며, 7.06K 워드의 코드 메모리와 12.19K 워드의 데이터 메모리를 사용하였다. 구현된 음성 부호화기는 ETSI에서 제공하는 시험 벡터 샘플을 모두 통과하였으며, 객관적 평가 툴을 이용하여 지각 평가를 수행한 결과, 32kbps ADPCM과 비슷한 음질을 보였다. 본 논문에서 실시간으로 구현된 GSM-EFR 음성 부호화기는 IMT2000 비동기 방식의 음성 부호화기 표준인 GSM-AMR의 최상위 전송률 모드로서. 앞으로 IMT-2000 비동기식 단말기용 모뎀 ASIC에 탑재할 GSM-AMR 음성부호화기의 구현을 위한 기본 구조로 이용될 예정이다.

• Proceedings of the KSPS conference
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• 2005.11a
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• pp.151-154
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• 2005

원거리 음성인식에서 인식률의 성능향상을 위해 필수적인 다채널 마이크 환경에서 방 안의 도처에 분산되어있는 원거리 마이크를 사용하여 TV, 조명 등의 주변 환경을 음성으로 제어하고자 한다. 이를 위해 각 채널의 인식결과를 통합하여 최적의 결과를 얻고자 채널의N-best 결과와 N-best 결과에 포함된 hypothesis의 frame-normalized likelihood 값을 사용하여 Bayesian network을 훈련하고 인식결과를 통합하여 최선의 결과를 decision 하는데 사용함으로써 원거리 음성인식의 성능을 향상시키고 또한 hands-free 응용을 현실화하기위한 방향을 제시한다.

• The Korean Journal of Nuclear Medicine
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• v.34 no.2
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• pp.119-128
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• 2000

Purpose: The aim of this study was to investigate the diagnostic role of $^{99m}Tc$-Tetrofosmin in detection of breast cancer and compared with that of $^{99m}Tc$-MIBI. Material and Methods: Forty-eight patients with a clinically palpable mass or abnormal mammographic or ultrasonographic findings had $^{99m}Tc-MIBI\;and\;^{99m}Tc$-Tetrofosmin scintimammographies after intravenous injection of 925 MBq of radiopharmaceuticals. The scintimammographs were correlated with histopathologic findings. Results: Thirty-three patients were diagnosed with breast cancer and 15 patients with benign breast diseases. The numbers of true positive, true negative, false positive, and false negative cases of $^{99m}Tc$-MIBI scintimammography were 29, 10, 5, and 4 respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of $^{99m}Tc$-MIBI scintimammographies were 87.8%, 66.7%, 85.3%, and 71.4% respectively. The numbers of true positive, true negative, false positive, and false negative cases of $^{99m}Tc$-Tetrofosmin were 31,10, 5, and 2 respectively. The sensitivity, specificity, positive predictive value, negative predictive value of $^{99m}Tc$-Tetrofosmin were 93.9%, 66.7%, 86.1%, and 73.3% respectively. One patient was false negative in both $^{99m}Tc-MIBI\;and\;^{99m}Tc$-Tetrofosmin acintimammographies and its size was 0.5 cm. Conclusion: $^{99m}Tc-Tetrofosmin\;and\;^{99m}Tc-MIBI$ were non-invasive and useful in detection of breast cancer and $^{99m}Tc$-Tetrofosmin was comparable to the $^{99m}Tc$-MIBI in detection of primary breast cancer.

• Journal of the Korean Society of Radiology
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• v.6 no.1
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• pp.63-71
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• 2012

This study aimed to evaluate the accuracy of breast cancer diagnosis of digital mammography which is in the highest interest of breast imaging test, and to investigate the characteristics of breast cancer patients. For this purpose, 57 breast cancer patients who underwent breast imaging test were examined between May 2010 and June 2011. The average age of the breast cancer patients was 50.8 years old, and the most frequently occurring location was the upper outer quadrant (UOQ), accounting for 33.3%. By age, the highest occurrence rate of breast cancer was the age group of 40~49, accounting for 42.1%. As for the breast composition of the breast cancer patients, fatty breast accounted for 31.6% (18/57) and dense breast for 68.4% (39/57), indicating that nearly 70% of the breast cancer patients have dense breast. It was found that the detection rate of breast cancer was the highest (45.3%) when both microcalcification and mass are simultaneously present in the radiographic lesion of the breast imaging. In dense breast, the mass without microcalcification was lower in detection rate than fatty breast. Accordingly, the mass is the cause of raising the false negative rate in dense breast. The findings show that the false negative rate of digital mammography was 7.0% and the sensitivity 93.0%. Also, the false negative rate of dense breast was 12.8%, and the sensitivity 87.2%, indicating that the sensitivity to breast cancer in this study was higher than the dense breast of previously reported screen film mammography.

• Proceedings of the Korea Multimedia Society Conference
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• 1998.10a
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• pp.226-231
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• 1998

본 연구에서는 짧은 시간에 계산이 가능하며, 음성을 특징 지울 수 있는 파라미터로서 영 교차율(zero crossing rate), 단 구간 에너지(short-term, energy) 그리고 포만트(formant)를 사용하였다. 특정 화자의 음성을 입력 받아서 단모음인 'ㅏ, ㅐ, ㅓ, ㅔ, ㅗ, ㅜ, ㅡ. ㅣ'에 대한 인식을 위해 위의 세가지 파라미터를 측정하였다. 영 교차율과 단 구간 에너지 파라미터는 유성음과 무성음의 구별과 음성인지 아닌지를 판별하는데 사용하였다. 포만트 파라미터는 10차 켑스트럼(cepstrum)을 이용하여 구하였으며, 각 단모음을 판별하기 위해서 사용하였다. 하나의 단모음을 입력받아 처리하여 텍스트로 출력하는데 평균 0.065sec에 처리하며, 각각의 단모음에 대해 93%, 10개의 테스트 문장에 대해 72%의 인식률을 보이고 있다.

• Proceedings of the Korean Information Science Society Conference
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• 2000.04b
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• pp.354-356
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• 2000

의사형태소를 디코딩 단위로 한국어 연속 음성 인식에서의 조사, 어미, 접사 및 짧은 용언의 어간등의 단어가 상당수의 인식 오류를 발생시킨다. 이러한 단어들은 발화 지속시간이 매우 짧고 생략이 빈번하며 결합되는 다른 형태소의 형태에 따라서 매우 심한 발음상의 변이를 보인다. 본 논문에서는 이러한 단어들은 한국어 기능어라 정의하고 실제 의사형태소 단위의 인식 실험을 통하여 기능어 집합 1, 2를 규정하였다. 그리고 한국어 기능어에 기능어용 음소를 독립적으로 적용하는 방법을 제안했다. 또한 기능어용 음소가 분리되어 생기는 음향학적 변이들을 처리하기 위해 Gaussian Mixture 수를 증가시켜 보다 견고한 학습을 수행했고, 기능어들의 음향 모델 스코어가 높아짐에 따른 인식에서의 삽입 오류 증가를 낮추기 위해 언어 모델에 fixed penalty를 부여하였다. 기능어 집합1에 대한 음소 모델을 적용한 경우 전체 문장 인식률은 0.8% 향상되었고 기능어 집합2에 대한 기능어 음소 모델을 적용하였을 때 전체 문장 인식률은 1.4% 증가하였다. 위의 실험 결과를 통하여 한국어 기능어에 대해 새로운 음소를 적용하여 독립적으로 학습하여 인식을 수행하는 것이 효과적임을 확인하였다.

• Journal of radiological science and technology
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• v.34 no.1
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• pp.1-7
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• 2011

The purpose of this study is to evaluate the diagnostic accuracy of breast cancer from mammography images and to investigate the characteristics of patients who was diagnosed as a breast cancer. The subjects for this study were 85 patients who underwent breast imaging test with screen-film method and investigated from March 2010 to October 2010. The average age of the subjects is 51.9 years old. The 43.5% of onsets were located at the upper outer quadrant (UOQ). In terms of the age group, group for 40-49 ages were highest 37.6 (32/85)%. As for breast composition, fatty and dense breast were 30.6% (26/85) and 69.4% (59/85) respectively. The average age of the patients with fatty breast is 62.4 years old, whereas those with dense breast was 46.5 years old. The false negative rate of mammography images was 27.1% (23/85) and the sensitivity of mammography was 72.9% (62/85). The false negative rate of the patients with dense breast was 32.2% (19/59). the sensitivity of them was 67.8% (40/59).

• Biomedical Science Letters
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• v.5 no.2
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• pp.191-200
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• 1999

In recent years continuously increasing number of tuberculosis (TB) cases due to the emergence of strains with multidrug resistance and AIDS is a significant global health problem. Therefore, more rapid and reliable diagnosis of TB may be one of the most urgent needs in efforts to eradicate the disease. The present study was designed to compare and assess the diagnostic values and efficiencies between the conventional methods (X-ray, AFB stain and culture) and PCR for pulmonary TB on 171 cases. Chest X-ray finding and clinical features revealed that 39 (22.8%) of 171 sputum specimens were pulmonary TB cases. The statistical data were taken on the basis of the definitive diagnosis: In X-ray, overall sensitivity, specificity, efficiency and false positive and false negative incidence was respectively 69.2%, 87.1％, 83.0%, 12.9%, and 30.8％； 79.5%, 95.5%, 91.8%,4.6％ and 20.5％ in AFB-stain; 56.4%, 99.2%,89.5%, 0.8% and 43.6% in culture; 82.1%, 96.2%, 93.0%, 3.8% and 17.9% in PCR. PCR got a highest sensitivity and efficiency as well as a lowest false negative incidence. Culture had a highest specificity with a lowest false positive incidence. These results imply that PCR assay is fast, sensitive and efficient method for diagnosis of pulmonary TB. However, combined use of the conventional methods with thorough quality control may offer more opportunities for detecting Mycobacterium tuberculosis and diagnosting TB although they have some limits.

• The Journal of the Korea Contents Association
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• v.17 no.11
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• pp.50-59
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• 2017

To evaluate the capability of integrated PET-MRI, which has recently been utilized in the clinical practices, on the diagnosis of liver cancer, its utility was assessed by $2{\times}2$ decision matrix. The numbers of abnormal and normal decisions on the liver cancer were 98 and 51 cases, respectively, upon PET-MRI scan results of the subjects, and the numbers of positive and negative decisions were 103 and 62, respectively, upon cytopathologic results. Out of the two tests, 95 cases were shown as true-positive and 3 were false positive, while 62 were true negative and 5 were false negative. Upon the results of PET-MRI test, its sensitivity, specificity, false negative rate, and false positive rate were 95.00%, 95.38%, 0.05%, and 95.15%, respectively. Therefore, it is considered to have the high potential to use the determination of the stage before the surgery, detections of recurrence and remote metastasis, assessment of uncertain remote lymph node metastasis, and so on in the diagnosis of the liver cancer, and also for the clinical utility of PET-MRI to be sufficient by integrated diagnosis and follow up scan with pathological studies.