• Title/Summary/Keyword: 원자력연구소

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Genotoxicological Safety of Undaria pinnatifida Gamma-irradiated after Harvest (감마선 조사된 채취 미역의 유전독성학적 안전성 평가)

  • Choi, Jong-il;Kim, Jae-Hun;Song, Beom-Seok;Kim, Jaekyung;Lee, Ju-Woon;Chun, Byung-Soo;Ahn, Dong-Hyun;Byun, Myung-Woo;Park, Kyung-Sook
    • Journal of Radiation Industry
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    • v.5 no.1
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    • pp.81-86
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    • 2011
  • This study was conducted to evaluate the genotoxcity of gamma-irradiated Undaria pinnadifida after harvest for enhancing the storage and microbial safety during drying process. The harvested seaweed was irradiated with the doses of 1 and 10 kGy. The genotoxicity was evaluated by Ames test (Salmonella typhimurium reversion assay) and SOS chromotest. The results from all samples were negative in the bacterial reversion assay with S. typhimurium TA98 and TA100. No mutagenicity was detected in the assay, at both with and without metabolic activation. The SOS chromotest also indicated that the gamma-irradiated U. pinnadifida did not show any mutagenicity. Therefore, this study indicated that gamma irradiation could be used for extending the shelf-life of U. pinnadifida.

Preparation of Polyethylene Foam Sheets Crosslinked by Gamma-ray Irradiation (감마선 조사에 의하여 가교된 폴리에틸렌 발포 시트의 제조)

  • Lee, Dong-Hoon;Choi, Jun-Ho;Shim, Ki-Hyung;Jung, Chan-Hee;Hwang, In-Tae;Choi, Jae-Hak
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.211-215
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    • 2012
  • In this study, crosslinked polyethylene (PE) foam sheets were prepared through gamma-ray irradiation. PE foam sheets were prepared through a foaming process using sodium bicarbonate as a blowing and foaming agent. The prepared PE foam sheets were then crosslinked through gamma-ray irradiation. The crosslinking degree was increased to 86.0% with an increase in the absorption dose. The tensile strength of the crosslinked PE foam sheets was increased with an increase in the absorption dose. However, the elongation-at-break of the crosslinked PE foam sheets was decreased. The thermal decomposition temperature of the crosslinked PE foam sheets was increased to $421.2^{\circ}C$ with an increase in the absorption dose. The SEM analysis revealed that the morphology was not changed significantly after the crosslinking through gamma-ray irradiation.

Sensory Evaluation of Korean Seaweed Soup, Miyukgook, with Gamma-irradiated Undaria pinnatifida (감마선 조사된 미역으로 제조한 미역국의 관능 연구)

  • Choi, Jong-il;Kim, Jae-Hun;Song, Beom-Seok;Kim, Jaekyung;Lee, Ju-Woon;Chun, Byung-Soo;Ahn, Dong-Hyun;Byun, Myung-Woo;Park, Kyung-Sook
    • Journal of Radiation Industry
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    • v.5 no.1
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    • pp.21-24
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    • 2011
  • This study was conducted to evaluated the sensory properties of Miyukgook, Korean seaweed soup, with gamma-irradiated Undaria pinnadifida for enhancing the storage of the harvested seaweed. The harvested seaweed was irradiated at the doses of 1, 3, 5, and 10 kGy. The Miyukgook was made by following the general recipe. The values of pH and acidity of the Miyukgook were not changed by the irradiation of harvested Undaria. The sensory evaluation result showed that the preference scores in all the sensory properties was a little decreased when it was irradiated, but sensory score of less than 5 kGy samples was similar in all terms. Therefore, it was considered that gamma irradiation with less than 5 kGy was effective for improvement of the storage stability of U. pinnatifida without the changes in the sensory of its major cooked food, Miyukgook.

Antibacterial Effect of PVP/PEG/Carrageenan/Silver Acetate Hydrogels by γ-ray (γ-ray를 이용하여 합성한 PVP/PEG/Carrageenan/Silver acetate 하이드로겔의 항균효과)

  • Lim, Youn-Mook;Youn, Young;Gwon, Hui-Jeong;Park, Jong-Seok;Nho, Young-Chang
    • Journal of Radiation Industry
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    • v.4 no.1
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    • pp.73-77
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    • 2010
  • In recent day, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinifectant and biocidal material against coliforms and viruses. In this study, hydrogels containing silver acetate as antibacterial agent have been prepared using gamma rays irradiation. The hydrogels are composed of poly(vinyl pyrrolidone) (PVP), poly(ethylene glycol) (PEG), carrageenan and silver acetate. The concentration of solution was 9 wt%. The ratio of PVP : PEG : carrageenan was 6 : 1 : 2. The concentration of the silver acetate were 0, 0.01, 0.03, 0.05 and 0.07% and Gamma irradiation dose was 25 kGy. The Gamma irradiation dose in hydrogels with 0.01% silver acetate were 20 kGy, 35 kGy, 50 kGy, 65 kGy, and 80 kGy. The results showed that 0.01% silver acetate concentration of hydrogels by 25 kGy irradiation dose showed the highest antibacterial activity against E. coli and Staphylococcus aureus. Moreover, antibacterial activity of various Gamma irradiation dose in hydrogels treated 0.01% silver acetate showed highest 35 kGy irradiation dose against Staphylococcus aureus.

Synthesis of 125I-Labeled Gold Nanoparticles for a Molecular Imaging (분자영상용 방사성 금 나노입자 합성)

  • Son, Min Ju;Rho, Jong Kook;Lee, Joo-Sang;Jang, Beom-Su;Park, Sang Hyun
    • Journal of Radiation Industry
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    • v.6 no.2
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    • pp.139-145
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    • 2012
  • Gold nanoparticles (GNPs) have led to the development of a new field in the diagnosis and treatment of diseases such as cancer. An efficient synthesis of gold nanoparticles within the range of 8~57 nm was established by ${\gamma}-ray$ irradiation. The good point of a radiation-based method is the production of gold nanoparticles with a higher concentration and narrower size distribution compared with conventional methods. The size of gold nanoparticles was controlled using two methods. : (i) varying the ${\gamma}-ray$ irradiation dose of 10 to 25 kGy and (ii) varying the concentration of $HAuCl_4$ solution from 4 to 40 mM. In addition, the GNPs were radiolabeled using $[^{125}I]NaI$ in a simple and fast manner with high yields. The produced gold nanoparticles were characterized using a transmission electron microscopy (TEM), a UV-visible spectrophotometer, and a radio-TLC imaging scanner. From these results, these radiolabeled GNPs can be applicable for a radioisotope tag of biomolecules.

Feasibility Study on Silver Nanoparticle Application to a Radioisotope Carrier (은나노입자의 방사성 동위원소 운반체 적용 유효성 검증 연구)

  • Jang, Beom-Su;Lee, Joo-Sang;Park, Hae-Jun;Kim, Hwa-Jung;Park, Sang Hyun
    • Journal of Radiation Industry
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    • v.5 no.3
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    • pp.197-202
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    • 2011
  • In this study, an Ag-polyaniline-silica (Ag-PANI-silica) nanoparticle was evaluated as a radioisotope carrier. An Ag-PANI-silica nanoparticle was incubated in the $^{125}I$ solution for a duration of 24 hr to test its radioisotope absorptivity. During the incubation, radioactivity of the nanoparticle was measured at 3, 6, 12, and 24 hr. After a 24 hr incubation, $^{125}I$-Ag-PANI-silica nanoparticle was incubated in a fresh saline for a duration of 48 hr to check its stability. Additionally, the $^{125}I$-Ag-PANI-silica nanoparticle was injected to the ICR mouse to investigate its in-vivo distribution characteristics. The $^{125}I$ absorption yield of the Ag-PANI-silica nanoparticle was higher than 95% after a 6 hr incubation period in the $^{125}I$ solution. And $^{125}I$-Ag-PANI-silica was stable for 48 hr at 80% yield at room temperature. The SPECT/CT image of a mouse that received $^{125}I$-Ag-PANI-silica complex showed that the $^{125}I$-Ag-PANI-silica complex was distributed in the lung, stomach and thyroid at 30 min post injection. From these results, the Ag-PANI-silica nanoparticle has good radio-iodine carrying property and can be applicable for the purpose of diagnosis and therapy.

Preparation and Characterization of Gelatin Scaffold Containing Microorganism Fermented Cellulose (미생물 발효 셀룰로오스와 젤라틴을 함유한 조직공학적 세포지지체의 제조 및 특성)

  • Lim, Youn-Mook;Kim, Mi-Yeong;Gwon, Hui-Jeong;Park, Jong-Seok;Nho, Young-Chang;Lee, Byeon-Heon;Lee, Jong-Dae;Song, Sung-Gi;Kim, Sung-Ho;Choi, Young-Hun;Lee, Sun-Yi
    • Journal of Radiation Industry
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    • v.4 no.4
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    • pp.373-379
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    • 2010
  • Cellulose, chitin, chitosan and hyaluronic acid are well known as polysaccharides. These polysaccharides have many effects on cell growth and differentiation. Cell activation increases with increasing the polysaccharides concentration. In this study, gelatin scaffold containing microorganism fermented cellulose, citrus gel were prepared by using irradiation technique. Physical properties of the scaffolds were investigated as a function of the concentrations of gelatin and citrus gel and the cell attachment, cell morphology and inflammation of the scaffolds also were characterized for regeneration of skin tissue.

Evaluation of Physical Properties of Ethylene Vinyl Acetate/Silicone Emulsion for Radon Shielding Prepared by Electron-beam Irradiation (전자선 조사에 의해 제조된 라돈 차폐용 ethylene vinyl acetate/silicone 에멀젼의 물리적 특성 평가)

  • Jong-Seok Park;Jang-Gun Lee;Sung-In Jeong;Jun-Pyo Jeon;Yoon-Mook Lim;Jae-Hak Choi;Kap-Soo Kim
    • Journal of Radiation Industry
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    • v.17 no.4
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    • pp.369-375
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    • 2023
  • Radon, a carcinogenic substance generated from soil or building materials, have to be fundamentally blocked from entering indoors. In this study, ethylene vinyl acetate (EVA)/silicone emulsions with excellent mechanical and thermal properties and effective blocking of radon gas were prepared by using radiation technology. As the electron-beam irradiation does increased, a partially crosslinked structure was formed in EVA molecular chain, increasing tensile properties and adhesive strength. The EVA/silicone film showed excellent thermal stability without deformation. In addition, the non-irradiated EVA/silicone film showed a radon blocking rate of about a 75%, while the EVA/silicone film irradiated with 3 and 5 kGy showed an excellent radon blocking rate of over 90% due to the formation of crosslinked structure in the EVA molecular chain. These results indicated that the radiation technology can effectively block radon by forming a partially crosslinked structure of EVA/silicone emulsion to improve tensile property, adhesive strength, and deformation stability.

Characterization of Electron Beam Cured Epoxy Acrylate (에폭시 아크릴레이트의 전자선 영향 평가)

  • Shin, Jin-Wook;Oh, Byung-Hwan;Ko, Keum-Jin;Jeun, Joon Pyo;Kang, Phil Hyun
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.271-276
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    • 2010
  • Epoxy resin has wide application in various industrial fields because of their good mechanical strength, superiority adhesion and low shrinkage etc. And the typical curing method for epoxy resins is thermal and press compaction. However, a curing method was used electron beam process in this study. Epoxy acrylate was fabricated from mixture of epoxy, acrylic acid, tetraphenylporphyrin (TPP) and hydroquinone monomethyl ether (MEHQ) with mole ratios. Then electron beam irradiation effect on the curing of the epoxy acrylate resin was investigated various absorption dose in nitrogen atmospheres at room temperature. The dynamic mechanical and thermal properties of the irradiated epoxy acrylate resins were characterized using dynamic mechanical analysis (DMA) and thermogravimetric analyzer (TGA). And the tensile and flexural strength were measured by an universal tensile machine (UTM).

Study on Decomposition of Several Pesticides by Gamma-Irradiation (감마선 조사에 의한 농약 성분의 분해 연구)

  • Lee, Joo-Sang;Jung, Su-Yeon;Oh, Seung-Yeol;Jang, Beom-Su;Park, Sang Hyun
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.205-209
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    • 2012
  • The decomposition of 50 pesticides present in an aqueous solution using ${\gamma}-irradiation$ from a $^{60}Co$ gamma-ray source was investigated using laboratory-scale experiment. The rates of decomposition were determined using a gas chromatography-electron capture detector (GC-ECD), high-performance liquid chromatography-photo diode array detector (HPLC-PDA), and HPLC-fluorescence detector (FLD). When the initial concentration of pesticides was 10 ppm, and the radiation dose was 2, 5, 10, 20, and 30 kGy, respectively, 14 pesticide samples showed high removal rates (>50%) at absorbed doses of more than 10 kGy. With the exception of procymidone, they were all completely removed at a 30 kGy irradiation dose. These results provide fundamental data on the reactivity between gamma-irradiation and pesticides in an aqueous solution. Further, an evaluation of the toxicity of radiolytic intermediate products is required.