• 제목/요약/키워드: 원자력연구소

검색결과 657건 처리시간 0.021초

전자선 조사를 이용한 히알루론산의 특성 조절 (Modulation of Hyaluronic Acid Properties by Electron Beam Irradiation)

  • 신영민;김우진;김용수;조선영;박종석;권희정;임윤묵;노영창
    • 방사선산업학회지
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    • 제5권2호
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    • pp.159-164
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    • 2011
  • A variety of natural polymers have been used as tissue engineering scaffolds, drug delivery system, and cosmetic materials due to their higher biocompatibility and water uptake. As a major component of extracellular matrix, hyaluronic acid consisting of D-glucuronic acid and N-acetylglucosamine has been popularly used as a hydrogel material. Even though it has good properties to be used in the tissue engineering and cosmetic industry, its higher viscosity has limited a potential use in a variety of applications; only low content should be applied in preparing above products. In the present study, we investigated the effect of electron beam irradiation on the properties of hyaluronic acid. Hyaluronic acid paste containing low contents of water changed to solution after electron beam irradiation ranging from 1 to 10 kGy, which didn't exhibit any alteration of surface properties and morphological change after freeze-drying. However, its viscosity was significantly decreased as absorbed dose increased, which was approximately one by hundred in comparison with the viscosity of original hyaluronic acid solution with same concentration. In addition, it can still interact with positive charged chitosan generating polyelectrolyte complex. Therefore, only viscosity was decreased after electron beam irradiation, whereas other properties of hyaluronic acid maintained. Consequently, these hyaluronic acids with lower viscosities can be used in a variety of applications in tissue engineering, drug delivery, and cosmetic industry.

감마선 조사에 따른 동결건조과일의 품질 특성 평가 (Evaluation of Quality Properties of Gamma-irradiated Freeze-dried Fruits)

  • 최수정;윤영민;한인준;김재경;박종흠;이주운;류은순;육홍선;김재훈;송범석
    • 방사선산업학회지
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    • 제6권4호
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    • pp.299-304
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    • 2012
  • The quality properties of freeze-dried apples, pears, strawberries and pineapples gamma-irradiated at 0, 1, 2, 3, 4, and 5 kGy were evaluated to develop germ-free products for immuno-compromised patients. The initial count of total aerobic bacteria in non-irradiated apples, pears, strawberries and pineapple was 2.5, 3.1, 2.6, and $3.2{\log}\;CFU{\cdot}g^{-1}$, respectively. Microorganisms were not observed in apples after 1 kGy, in pears and strawberries after 4 kGy, and in pineapples at 5 kGy within a detection limit of $10{\log}\;CFU{\cdot}g^{-1}$. In addition, the sterilization of each sample was confirmed at the same dose. The score for the overall acceptance of freeze-dried fruit irradiated at a sterilization dose was 5.5 for apples, 4.1 for pineapples, and 4.0 for the other fruits, whereas that of non-irradiated control sample was 5.6 for apples, 5.2 for pears, and 5.8 for strawberries and pineapples with a 7-point scale. As a result, gamma irradiation of 1 kGy for apples, 4 kGy for strawberries and pears, and 5 kGy for pineapples is sufficient to sterilize each freeze-dried fruit with acceptable sensory properties.

감마선 조사 유래 블랙베리(Rubus fructicosus L.) 돌연변이 계통의 농업부산물 사료가치 분석 (Forage Quality Evaluation of Mutant Lines derived from Gamma-ray Treatments in Rubus fructicosus L.)

  • 류재혁;김동섭;하보근;김진백;김상훈;안준우;정일윤;조한직;김이엽;강시용
    • 방사선산업학회지
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    • 제7권1호
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    • pp.37-43
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    • 2013
  • We examined the forage quality to provide the basic information for the utilization of blackberry by-products (leaf and stem) among thirty-five mutant lines derived from gamma-ray. The leaves had higher crude protein (CP) contents than stems. In addition, the leaves showed broad ranges of variation in crude fat, crude fiber and crude ash. The overall forage quality of the stems were similar to those of the original variety. The mean of neutral detergent fiber (NDF) content of leaves and stems in mutant lines were 25.88% and 58.98%, respectively. Also, the mean of acid detergent fiber (ADF) content of leaves and stems in mutant lines were 15.43% and 49.27%, respectively. Forage quality grades of all blackberry leaf were special quality class. However, the blackberry stem ranked $1^{st}$ to $5^{th}$ in quality class. The stem diameter was negatively ($P{\leq}0.05$) correlated with the moisture and crude protein. Also, the fruit length was highly negatively ($P{\leq}0.01$) correlated with the RFV (relative feed value) in blackberry leaf. The one hundred fruit weight was highly negatively ($P{\leq}0.01$) correlated with the crude ash. Based on these results, the by-products of blackberry could provide high quality forage for feeding of live stock.

PSL, TL 및 ESR 분석을 통한 수입산 들깨, 아몬드 및 대두의 방사선 조사 여부 판별 특성 (Detection of Gamma-irradiated Imported Foods (Perilla seeds, Almonds, and Soybeans) by Using PSL, TL, and ESR)

  • 한인준;윤영민;최수정;송범석;김재경;박종흠;이주운;김재훈;김규헌;조태용;윤혜성;한상배;이정은
    • 방사선산업학회지
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    • 제6권4호
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    • pp.305-310
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    • 2012
  • This study examined radiation detection properties of imported perilla seeds, almonds, and soybeans. Food samples were irradiated at doses of 0.5, 1, 2, and 4 kGy and analyzed by photo-stimulated luminescence (PSL), thermoluminescence (TL), and electron spin resonance (ESR). The results of PSL showed that photon counts of irradiated perilla seeds and soybeans were $32,959counts{\cdot}60sec^{-1}$ and $7,234counts{\cdot}60sec^{-1}$, respectively, at an irradiation dose of 0.5 kGy, and the photon count of irradiated almonds was $5,581counts{\cdot}60sec^{-1}$ at an irradiation dose of 1 kGy. The results of TL showed that this technique is useful for detecting irradiated samples; the TL ratios ($TL_1/TL_2$) measured for the food samples at an irradiation dose of 0.5 kGy were 0.2301 for perilla seeds, 0.4595 for almonds, and 0.4827 for soy beans. Lastly, results of ESR spectroscopy for only soybeans revealed specific signals derived from free radicals captured in the cellulose. In conclusion, PSL, TL, and ESR methods can be used for the detection of gamma-irradiated soybean samples, whereas gamma-irradiated perilla seeds and almonds can be confirmed by a serial detection with a TL method after PSL.

중저준위방사성폐기물 처분장 인공방벽의 핵종유출 저지능 평가 (Performance Assessment of Engineered Barrier for Retardation of Radionuclide Release in a Low- and Intermediate-Level Radioactive Waste Repository)

  • 조원진;이재완;한필수;박헌휘
    • Nuclear Engineering and Technology
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    • 제25권3호
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    • pp.447-456
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    • 1993
  • 중저준위 방사성폐기물처분장 인공방벽의 핵종유출 저지능을 평가할 수 있는 단순 모델이 제안되었다. 이 모델은 현재 우리나라에서 제안되고 있는 처분장 개념을 고려하여 고안되었으며, 인공방벽의 설계에 적합한 설계 기준 유출 과 인공방벽 성능평가에 적합한 현실적 유출 두 가지 경우를 다루고 있다. 모델의 유용성을 보이기 위해 화학적 특성이 다른 다섯 핵종에 대해 모의 계산을 수행하고 그 결과를 분석하였다.

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