• Radiation Oncology Journal
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• v.10 no.2
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• pp.205-212
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• 1992

Ninety five patients of rectal cancer treated with surgery with or without adjuvant radiation therapy since January 1982 to December 1990 at the Chonnam University Hospital were analysed retrospectively regarding local failure. Of these 95 patients 72 patients were treated with surgery alone and remaining 23 patients received postoperative radiation therapy to pelvis. There were 45 men and 50 women with 53 years of median age. Minimum follow-up period was 19 months and median was47 months (range, 19-125 months). Kaplan-Meier method was used to calculate actuarial risk of local recurrence and survival rate. Comparison between two groups was evaluated by Log rank test. Of total 95 patients twenty seven patients ($28.4\%$) developed local recurrence and 13 patients ($17.3\%$) developed local and distant metastasis concomitantly. Eighty nine percent (24/27) of patients developed local recurrence within 24 months. Pelvic organ adjacent to the primary tumor area was the most common site of initial local recurrence. Of 72 patients treated with surgery alone local recurrence developed in 24 patients. Of 17 patients with stage A and 81 (Gunderson-Sosin modification of Dukes' staging system) 6 patients experienced local recurrence ($31.2\%$). The local recurrence rate of B2 and B3 group was $29.9\%$ (7/33) and that of C2 and C3 was $54.7\%$ (11/19), respectively. There was statistically significant difference between two groups (p<0.05). Of 23 patients treated with definitive surgery and radiation therapy $10\%$ (1/10) recurred in B2 and B3 patients. This was slightly lower than C2 and C3 patients ($22.2\%$, 2/10) of similar policy, but revealed no statistically significant difference (p>0.05). In the patients of B2+3 local failure rate decreased when radiation therapy was added ($29.9\%$ vs $10\%$, p>0.05) and also similar results in C2+3 group ($34.7\%$ vs $22.2\%$, p<0.05). The local failure rate in relation to distance from the anal verge had no statistically significant difference.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.5 no.1
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• pp.39-52
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• 2007

Quantitative analysis on release behavior of the $^{85}Kr\;and\;^{14}C$ fission gases from the spent fuel material during the voloxidation and OREOX process has been performed. This thermal treatment step in a remote fabrication process to fabricate the dry-processed fuel from spent fuel has been used to obtain a fine powder The fractional release percent of fission gases from spent fuel materials with burn-up ranges from 27,000 MWd/tU to 65,000 MWd/tU have been evaluated by comparing the measured data with these initial inventories calculated by ORIGEN code. The release characteristics of $^{85}Kr\;and\;^{14}C$ fission gases during the voloxidation process at $500^{\circ}C$ seem to be closely linked to the degree of conversion efficiency of $UO_2\;to\;U_3O_8$ powder, and it is thus interpreted that the release from grain-boundary would be dominated during this step. The high release fraction of the fission gas from an oxidized powder during the OREOX process would be due to increase both in the gas diffusion at a temperature of $500^{\circ}C$ in a reduction step and in U atom mobility by the reduction. Therefore, it is believed that the fission gases release inventories in the OREOX step come from the inter-grain and inter-grain on $UO_2$ matrix. It is shown that the release fraction of $^{85}Kr\;and\;^{14}C$ fission gases during the voloxidation step would be increased as fuel burn-up increases, ranging from 6 to 12%, and a residual fission gas would completely be removed during the OREOX step. It seems that more effective treatment conditions for a removal of volatile fission gas are of powder formation by the oxidation in advance than the reduction of spent fuel at the higher temperature.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.37 no.3
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• pp.163-173
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• 2001

The dynamic behavior characteristics of a small fishing crane for inshore and coastal fishing vessels was experimentally analyzed in order to improve the fishing operation and to reduce considerably manual work of fisherman. The small fishing crane was designed to be controlled electro-hydraulically by means of proportional valves and solenoid valves, and also to be controlled the speed of each operation. The dynamic behavior characteristics was investigated by measuring the changes of parameters such as oil pressure, swing angle of load, load tension, the lifting angle and the swing angle of crane arm when the arms extended in a side way was given a test load. The results obtained are summarized as follows: 1. The designed small fishing crane can be proportionally controlled by means of proportional valves and rapidly by operating the solenoid valves, respectively. The capacity, turning angle, maximum reach of crane were 2 T-M, $180^\circ$, 3.7m, respectively. 2. The vertical change of crane arm on the extension of lifting cylinder was $1.2^\circ$/cm, and the swing speed of crane arm due to the extension of swing cylinder by on/off operations of solenoid valves was $15^\circ$/sec, with the swing period of 1.4 sec and the angle fluctuation of $\pm$11.0$^{\circ}$. 3. When changing simultaneously the horizontal and vertical positions of the lifting load by on/off operations of solenoid valves, the swing and lifting speeds of crane arm were $4.46^\circ$/sec and $6.4^\circ$/sec, respectively. 4. The movements of the designed crane were particularly smooth as they are controlled with the aid of proportional valves than by means of solenoid valves.

• Journal of the Korean Association of Geographic Information Studies
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• v.5 no.2
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• pp.1-15
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• 2002

Atmospheric aerosols interact with sunlight and affect the global radiation balance that can cause climate change through direct and indirect radiative forcing. Because of the spatial and temporal uncertainty of aerosols in atmosphere, aerosol characteristics are not considered through GCMs (General Circulation Model). Therefor it is important physical and optical characteristics should be evaluated to assess climate change and radiative effect by atmospheric aerosols. In this study GMS-5 satellite data and surface measurement data were analyzed using a radiative transfer model for the Yellow Sand event of April 7~8, 2000 in order to investigate the atmospheric radiative effects of Yellow Sand aerosols, MODTRAN3 simulation results enable to inform the relation between satellite channel albedo and aerosol optical thickness(AOT). From this relation AOT was retreived from GMS-5 visible channel. The variance observations of satellite images enable remote sensing of the Yellow Sand particles. Back trajectory analysis was performed to track the air mass from the Gobi desert passing through Korean peninsular with high AOT value measured by ground based measurement. The comparison GMS-5 AOT to ground measured RSR aerosol optical depth(AOD) show that for Yellow Sand aerosols, the albedo measured over ocean surfaces can be used to obtain the aerosol optical thickness using appropriate aerosol model within an error of about 10%. In addition, LIDAR network measurements and backward trajectory model showed characteristics and appearance of Yellow Sand during Yellow Sand events. These data will be good supporting for monitoring of Yellow Sand aerosols.

• Radiation Oncology Journal
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• v.12 no.1
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• pp.1-8
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• 1994

When cells are exposed to low doses of a mutagenic or clastogenic agents. they often become less sensitive to the effects of a higher dose administered subsequently. Such adaptive responses were first described in Escherichia coli and mammalian cells to low doses of an alkylating agent. Since most of the studies have been carried out with human lymphocytes, it is urgently necessary to study this effect in different cellular systems. Its relation with inherent cellular radiosensitivity and underlying mechanism also remain to be answered. In this study, adaptive response by 1 cGy of gamma rays was investigated in three human lymphoblastoid cell lines which were derived from ataxia telangiectasia homozygote, ataxia telangiectasia heterozygote, and normal individual. Experiments were carried out by delivering 1 cGy followed by 50 cGy of gamma radiation and chromatid breaks were scored as an endpoint. The results indicate that prior exposure to 1 cGy of gamma rays reduces the number of chromatid breaks induced by subsequent higher dose (50 cGy), The expression of this adaptive response was similar among three cell lines despite of their different radiosensitivity. When 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, was added after 50 cGy, adaptive responses were abolished in all the tested cell lines. Therefore it is suggested that the adaptive response can be observed in human lymphoblastoid cell lines, which was first documented through this study. The expression of adaptive response was similar among the cell lines regardless of their radiosensitivity. The elimination of the adaptive response by 3-aminobenzamide is consistent with the proposal that this adaptive response is the result of the induction of a certain chromosomal repair mechanism.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.1
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• pp.26-32
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• 2014

Purpose: As PET-MRI which has excellent soft tissue contrast is developed as integration system, many researches about clinical application are being conducted by comparing with existing display equipments. Because PET-MRI is actively used for head and neck cancer diagnosis in our hospital, lymph node metastasis before the patient's surgery was diagnosed and clinical usefulness of head and neck cancer PET-MRI scan was evaluated using pathological opinions and idiopathy surrounding tissue metastasis evaluation method. Materials and Methods: Targeting 100 head and neck cancer patients in SNUH from January to August in 2013. $^{18}F-FDG$ (5.18 MBq/kg) was intravenous injected and after 60 min of rest, torso (body TIM coil, Vibe-Dixon) and dedication (head-neck TIM coil, UTE, Dotarem injection) scans were conducted using $Bio-graph^{TM}$ mMR 3T (SIEMENS, Munich). Data were reorganized using iterative reconstruction and lymph node metastasis was read with Syngo.Via workstation. Subsequently, pathological observations and diagnosis before-and-after surgery were examined with integrated medical information system (EMR, best-care) in SNUH. Patient's diagnostic information was entered in each category of $2{\times}2$ decision matrix and was classified into true positive (TP), true negative (TN), false positive (FP) and false negative (FN). Based on these classified test results, sensitivity, specificity, accuracy, false negative and false positive rate were calculated. Results: In PET-MRI scan results of head and neck cancer patients, positive and negative cases of lymph node metastasis were 49 and 51 cases respectively and positive and negative lymph node metastasis through before-and-after surgery pathological results were 46 and 54 cases respectively. In both tests, TP which received positive lymph node metastasis were analyzed as 34 cases, FP which received positive lymph node metastasis in PET-MRI scan but received negative lymph node metastasis in pathological test were 4 cases, FN which received negative lymph node metastasis but received positive lymph node metastasis in pathological test was 1 case, and TN which received negative lymph node metastasis in both two tests were 50 cases. Based on these data, sensitivity in PET-MRI scan of head and neck cancer patient was identified to be 97.8%, specificity was 92.5%, accuracy was 95%, FN rate was 2.1% and FP rate was 7.00% respectively. Conclusion: PET-MRI which can apply the acquired functional information using high tissue contrast and various sequences was considered to be useful in determining the weapons before-and-after surgery in head and neck cancer diagnosis or in the evaluation of recurrence and remote detection of metastasis and uncertain idiopathy cervical lymph node metastasis. Additionally, clinical usefulness of PET-MRI through pathological test and integrated diagnosis and follow-up scan was considered to be sufficient as a standard diagnosis scan of head and neck cancer, and additional researches about the development of optimum MR sequence and clinical application are required.

• The Journal of Engineering Geology
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• v.9 no.2
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• pp.161-176
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• 1999

The objectives of this study are to analyze the changes of geo-surface topography in the Siwha embankment and the Ahsan city area by the image processing of Landsat Thematic Mapper data, and to estimate the reclaimed amount of the exposed tidal flat in the Siwha area using the GIS. False color composite, Tasseled cap, NVDI(normalized difference vegetation index), and supervised classification techniques were used to analyze the distribution of sediments and the aspect of topographical variations caused by artificial human actions. The total amount of the exposed tidal flat was estimated on the basis of the database snch as aerial photography, hydrographic chart, geological map, and scheme drawing in the Siwha area. The possible excavation regions for a seawall were predicted analyzing the supervised classification image of Landsat TM data. Tasseled cap images were used to observe the distribution of sediments. The difference of the NDVI images between spring and summer seasons indicates that deciduous and coniferous forests were distributed over the whole areas. The total fill-volume of the exposed Siwha tidal flat and the fill-volume of the construction planning seawall were calculated as $581,485,354\textrm{m}^3{\;}and{\;}3,387,360\textrm{m}^3$, respectively, from the digital terrain analysis. Daebu Island, Sunkam Island, and the part of Songsan-myeon were chosen as the cut area to make the seawall, and their cut-volumes were estimated as $5,229,576\textrm{m}^3,{\;}79,227,072\textrm{m}^3,{\;}and{\;}47,026,008\textrm{m}^3$, respectively. Therefore, the cut-volume of Daebu Island alone among three areas was sufficient to make the seawall.

• Tuberculosis and Respiratory Diseases
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• v.46 no.4
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• pp.542-547
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• 1999

Background: Decision in mediastinal lymph node involvement of lung cancer by CT scan is very important and valuable for the treatment planning and prognosis prediction. In general, long diameter of mediastinal lymph node more than 15mm is used as criterion of lung cancer involvement. Adenocarci-noma has a tendency of early distant metastasis and micrometastasis, so adenocarcinoma may involve lymph node earlier and cannot be detected before lymph nodes are enlarged enough. The authors tried to determine the difference between two size criteria(15mm, 10mm) in adenocarcinoma for the detection of cancer involvement. Methods: Numbers of sample are 60 cases(male 46, female 14, median age: 61.5 years). According to pathology, squamous cancer 41, large cell cancer 2, adenocarcinoma 17. According to TNM stage, I 23, III 24, IIIA 13. Results : Mean long diameter of lymph node involvement is 16.0($\pm8.0$) mm in non-adenocarcinoma group, and that of adenocarcinoma group is 12.0($\pm3.2$) mm(p<0.05). If long diameter of lymph node larger than 15mm as involvement criterion is applied, sensitivity, specificity, positive predictive index, negative predictive index, accuracy of nonadenocarcinoma group are 54%, 100%, 100%, 83%, 86%, and those of adenocarcinoma group are 43%, 90%, 75%, 69%, 71%. If long diameter of lymph node larger than 10mm as involvement criterion is applied, sensitivity, specificity, positive predictive index. negative predictive index. accuracy of nonadenocarcinoma group are 65%, 77%, 61%, 92%, 79%, and those of adenocarcinoma group are 100%, 80%, 78%, 100%, 88%. Conclusion: Long diameter of lymph node larger than 10mm is more valuable criterion as lymph node involvement in adenocarcinoma of lungs.

• Geophysics and Geophysical Exploration
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• v.16 no.1
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• pp.18-26
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• 2013

Shear-wave velocity ($v_s$) structures beneath two seismic stations, JJU and JJB on the flanks of the volcano Halla on Jeju island, Korea, were estimated by receiver-function inversion and H-${\kappa}$ stacking applied to 150 teleseismic events ($M_W{\geq}5.5$) recorded since 2007. $P_S$ waves converted at the Moho discontinuity does not appear clearly for northwesterly back-azimuths ($207{\sim}409^{\circ}$, average $308^{\circ}$) at station JJU and southeasterly back-azimuths ($119{\sim}207^{\circ}C$, average $163^{\circ}$) at station JJB. This may be due to a gradual velocity increase at Moho or heterogeneity within the crust. The $v_s$ models derived by inversion of receiver functions indicate a distinct low velocity layer ($v_s{\leq}3.5km/s$; LVL) within the crust and a gradual increase in $v_s$ in the depth interval of 30 to 40 km. Within the radius of 18 km beneath station JJB, the LVL occurs at depths of 14 ~ 26 km and the 'Moho' ($v_s{\geq}4.3km/s$) is at 34 km depth. Ten kilometers to the west, within the radius of 16 km beneath station JJU, both the LVL and the Moho are significantly shallower, at depths of 14 to 24 km and 30 km, respectively. H-${\kappa}$ analyses for stations JJU and JJB yield estimated crustal thickness of 29 and 33 km and $v_p/v_s$ ratios of 1.64 and 1.75, respectively. The lesser $v_p/v_s$ ratio was derived for rocks nearest to th peak of the volcano.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.2
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• pp.30.1-30.1
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• 2018

일제 강점기를 지난 후 광복을 맞았지만, 전란의 폐허 속에 개설된 대학의 천문학과의 관측 시설들은 전문한 상태였다. 필자가 학부 재학 중이던 6-70년대까지도 시 시공(時空)의 흐름은 필요한 것을 직접 만들어 사용할 수밖에 없는 시대로 몰아가고 있었다. 당시를 회고 하며 지금까지 걸어 온 "천문기기 제작 연구의 삶"을 회고하고자 한다. 대학 재학 시절 교수님의 도움으로 막스토브 망원경을 제작하고, 40cm 카세그레인 망원경 등 광학계의 원리와 특성연구를 통해 부품 조립을 수행할 수 있었다. 태양 흑점관측을 위한 10cm 굴절 망원경의 투영시설을 고안하여 6개월 동안 관측하였지만. 석사 논문을 위해 광전측광 관측시스템을 제작하여 식쌍성 관측을 수행하였다. 그 결과 한국의 시설로 UBV 광도곡선 완성하여 1975년 가을 천문학회에서 발표하였다. 1976년 2월 국립천문대 천문계산연구실에 발령 받고 역서편찬 업무를 담당하면서 소백산 60cm 망원경 최종 설치를 끝내고, 천문대(현 역삼동 과총회관 빌딩) 옥상에 2m 규모의 목재 돔을 설계 제작하고 일반인들을 위한 대중천문 활동을 시작하였다. 재직 중에 항상 한국의 열악한 천문시설의 상황을 실감하고 20대를 마감하면서 퇴직하여 "한국천문기기 연구소"라는 명칭으로 천체 돔을 설계하고, 돔 제작기계를 개발하였다. 망원경만 보관 중인 국내 4개 대학에 돔을 납품 한 후 연세대학교 천문대의 직경 6m 스텐레스 돔을 제작하였다. 아울러 연세대 천문대 60cm망원경을 설치하면서 이 곳에 입사하여 관측 장비개발 연구와 관측에 전념하게 되었다. 재직 기간 중 대학의 배려로 카나다 국립천문대(DAO) 방문연구원으로 1.8m 망원경으로 식쌍성들의 분광관측을 수행하여 시선속도곡선을 완성하였고, 체류 중에 스텝들과 국내에서 사용할 60cm용 첨단 분광기를 설계하였으나 대학에 재원이 없어 제작을 못한 아쉬움이 남는다. 1989년 2월 충북대학교 천문우주학과에 부임하면서 열악한 상황이지만 교육과 연구 장비로 20cm와 35cm 소형 망원경의 디지털 광전측광시스템으로 간이 천문대를 설치하여 운영하였다. 학과 설립 10 주년(1998년)을 맞아 40cm 망원경과 6m 돔을 설치하여 교내천문대가 완공되었다. 2000년이 되면서 대중 천문활동 을 위해 이동 천문대를 제작하여 4륜 자동차에 견인하여 여러 지역을 찾아 관측과 강연 활동 등 학과의 대중천문 활동의 특성을 살리는 계기를 만들게 되었다. 학과 설립 20주년(2008년)을 맞으면서 충북 진천에 16개 자동분할 개폐식 스릿의 9m 돔 안에 1m 망원경을 원격관측 시설을 완비하여 대학 본부의 기관으로 충북대학교천문대를 개관하고 관측시설을 완비하였다. 우리의 전통적인 세종시대 천문시설은 당대 최대의 시설이지만 당시 유물들이 모두 소실되어 현존하는 것이 하나도 없음은 실로 아쉬움이 큰 것이었다. 누군가는 그 구조, 형태, 원리, 기능, 사용방법 등을 밝히고 복원을 시도해야 할 시급함이 있었다. 문헌을 통해 1991년부터 학부졸업 논문으로 "고천문 의기(儀器) 복원연구" 분야의 발표를 시작하였다. 그 결과를 통해 세종탄신일에 영릉에서 숭모제 행사 후 그 곳에서 수년간 세종시대 고천문의기 한가지씩 작동모델을 복원하여 제막식을 거행하였다, 유물복원 회사 (주)옛기술과 문화 와 함께 팀을 이루어 매년 제작할 종목을 준비하게 되었다. 간의(簡儀)를 복원한 후에는 일성정시의, 소간의, 앙부일구, 정남일구, 석각천문도, 혼천의, 혼상, 각종 해시계 등 매년 지속적으로 복원되어 큰 규모의 야외 전시장이 완성되었다. 작동모델 설계연구팀의 자문과 제작팀과의 팀웍으로 이룬 성과인 것이다. 한번 시작품이 발표된 모델들은 국내 과학관과 박물관, 천문관에서 후속 모델을 설치하였다. 한국천문연구원과 부산 동래읍성 내에 장영실 과학 동산은 간의와 혼상을 비롯한 각종 해시계들을 설치한 큰 규모의 야외 전시장이다. 조선의 명망 높은 유학자들이 인격적인 하늘을 살펴보았던 혼천의와 일만원권에 그려 있는 국보 230호 자명종 혼천시계(일만원권의 그림)의 작동 모델을 제작하였다. 이와 같은 연구 결과들은 석사과정 박사과정을 통하여 더 심층적인 연구들이 발표되었고, 각종 조선(한국)의 천문의기(天文儀器) 연구 자료들은 연구팀들을 통해 중국과 일본 등 해외에서도 발표되었다. 지금까지 복원된 유물들이 완성되기까지는 참여한 많은 연구원들과 제작팀들이 합심하여 각자의 역할을 수행하여 최종 작동모델들이 하나 둘 완성되는 것이었다. 이것은 참으로 보람된 일이었고, 은퇴 후 지금은 재능기부자로서 즐거운 삶을 이어 갈수 있게 되었다.