• Journal of the Korean Institute of Telematics and Electronics B
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• v.33B no.1
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• pp.178-186
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• 1996

We develop a simple adaptive population coding model for neural networks based upon an error minimization method. Our model exhibits properties that have been experimentally observed in the population coding of the motor-cortical cells during the voluntary arm movements of primates. By removing a group of directionally tuned cells after learning, we study its contribution to the population coding. Through the learning process of the remained cells, we observe how the cells modify their preferred directions to reduce the coding errors. Since this adaptive property has been neither predicted nor experimentally observed before, it would be interesting to find whether a similar adaptive property exists in real cortices that are believed to encode the information in their cell populations.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.4 no.1
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• pp.114-123
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• 1993

The authors applied Toddler Temperament Scale(TTS) to ADHD patient group, other disease group and normal control group to elucidate temperamental characteristics of ADHD patients in their toddler stage. 1) ADHD group showed significant difference from the control group in 'activity', 'rhythmicity', 'approach', 'adaptability', 'intensity', 'persistence' and 'threshold' categories. 2) ADHD group and other disease showed significant difference from the control group in 'adaptability' and 'persistence' categories. 3) ADHD group was significantly different from other disease group or control group in 'activity' and 'approach' categories. 4) In total scores of TTS, ADHD group and other diease group showed significant difference from control group. 5) Classification ratio of TTS for ADHD by discriminant analysis was 84.3%. Above results suggest that the ADHD patients may reveal characteristic traits in their toddler stage Further research should be focused on the development and refinement of assessment tools for the early detection and prevention for ADHD.

• Journal of Life Science
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• v.27 no.3
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• pp.361-369
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• 2017

Mitochondrial homeostasis is tightly regulated by two major processes: mitochondrial biogenesis and mitochondrial degradation by autophagy (mitophagy). Research in mitochondrial biogenesis in skeletal muscle in response to endurance exercise training has been well established, while the mechanisms regulating mitophagy and the relationship between mitochondrial biogenesis and degradation following endurance exercise training are not yet well defined. Studies have demonstrated that endurance exercise training increases the expression levels of mitochondrial biogenesis-, dynamics-, mitophagy-related genes in skeletal muscle. However, the increased levels of mitochondrial biogenesis marker proteins such as Cox IV and citrate synthase, by endurance exercise training were abolished when autophagy/mitophagy was inhibited in skeletal muscle. This suggests that both autophagy/mitophagy plays an important role in mitochondrial biogenesis/homeostasis and the coordination between the opposing processes may be important for skeletal muscle adaptation to endurance exercise training to improve metabolic function and endurance exercise performance. It is considered that endurance exercise training regulates each of these processes, mitochondrial biogenesis, fusion and fission events and autophagy/mitophagy, ensuring a relatively constant mitochondrial population. Exercise training may also have contributed to mitochondrial quality control which replaces old and/or unhealthy mitochondria with new and/or healthy ones in skeletal muscle. In this review paper, the molecular mechanisms regulating mitochondrial biogenesis and mitophagy and the coordination between the opposing processes is involved in the cellular adaptation to endurance exercise training in skeletal muscle will be discussed.

• Applied Microscopy
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• v.31 no.1
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• pp.59-70
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• 2001

The present study was to elucidate the cytochemical study on the cytochrome oxidase (CO) activity and myocardial adaptation to treadmill exercise in rat. The three month Sprague-Dowley male $(150{\pm}10g)$ were used in experimental animal. The experimental groups were divided into 2 groups: the normal sedentary group and the treadmill exercise group. On each 1st and 3rd day, 1st, 4th, 8th, and 12th experimental week four rats of each group were sacrificed for tests. The morphometrical measurements were used to evalute the change of heart weight, rate of myocardial fibers to capillaries, and cytochemical study of CO activities, using light and electron microscopy. The results were as follows: The heart weights were more increased in the treadmill exercise group than those of their sedentary group. The rate of myocardial fibers to capillaries were not changed in sedentary group, but those were significantly from 4th weeks in the treadmill exercise group. The CO activity was not changed in sedentary group, but increased in treadmill exercise group after 1 st week. I and III types of CO activity were increased In sedentary group, in contast to II and III types in treadmill exercise group on electron micrographic study. These results suggest that, the treadmill exercise-induced changes in CO activity and rate of myocardial fibers to capillaries appear to be related to exercise, and the adaptive response seems to occurs from 4th week of treadmill exercise.

• Journal of Life Science
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• v.17 no.8 s.88
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• pp.1166-1171
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• 2007

Exercise is the strongest stress to which the body is ever exposed. The body responds to this stress through a set of physiological changes in its metabolic, hormonal, and immunological systems. In this study, responses of the immune system to the long-term aerobic and anaerobic exercises have been investigated. Regular moderate exercise is associated with a reduced incidence of infection compared with a sedentary groups. Aerobic training increases the heart rate and enhances the body's intake of oxygen long enough to benefit the condition of the body. In recent years, the importance of exercise in everyday life has been rapidly increasing. Moderate exercise appears to stimulate the immune system. And also, Exercise elicits an increase in the numbers of circulating lymphocytes and lymphocyte subsets (including NK cells) which is followed by a decrease in the numbers of cells during recovery from exercise. However, prolonged bouts of strenuous exercise cause a temporary depression of various aspects of immune functions (e.g. lymphocyte proliferation, monocyte antigen presentation, open window periods, exercise induced asthma, exercise induced anaphylaxis) that usually lasts 2-24 hr after exercise depending on the intensity and duration of the exercise bout. Exercise-induced bronchoconstriction (EIB) was defined as a decrease of at least 15% in pre exercise forced expiratory volume in one second at any time point after exercise. This includes elevation of cortisol and cathecholamines in plasma. On the other hand, highly trained athletes exhibit a chronic mild hypercortisolism at baseline that maybe an adaptive change to chronic exercise. And, Consuming carbohydrate during prolonged strenuous exercise attenuates rises in stress hormones and appears to limit the degree of exercise-induced immune depression. Recent evidence suggests that antioxidant vitamin supplementation may also reduce exercise stress and impairment of leukocyte functions.

• 건강소식
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• v.26 no.4 s.281
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• pp.6-13
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• 2002

우리 몸은 적절한 운동을 함으로써 각각의 기능이 정상으로 적응하도록 되어있으며 적절한 운동을 하지 않으면 신체의 기능은 점점 약화되어 건강에 나쁜 영향을 주게 된다. 우리 주위의 많은 사람들은 이러한 사실을 알고 있어도, 시간이 없다는 핑계로, 다른 할 일이 많다는 핑계로 운동 부족을 자초하고 있다. 우리나라의 사망원인 순위를 보면 위기 암(악성신생물), 위가 뇌혈관 질환, 3위가 심장질환으로 식생활, 운동부족 등 잘못된 생활습관이나 스트레스등으로 인한 만성질환이다. 특히 운동부족은 심장병, 암, 당뇨병, 근골격계 질환(골다공증) 등의 위험요인이 되는데 운동부족과 밀접한 관계가 있는 허혈성 심질환의 경우 사망률이 1985년 인구 10만명당 3.8명에서 2000년 21.5명으로 5배 이상 증가하였으며 당뇨병의 경우 1985년 인구 10만명당 6.8명에서 2000년 22.6명으로 3배 이상 증가하였나(통계청, 200년 조사), 우리나라 성인들의 운동 실천율은 매우 낮은 편으로 규칙적으로 운동하는 사람의 비율이 0.8%에 머물러 운동부족의 심각성을 보여주고 있다(한국보건사회연구원 1998) 세계보건기구(WHO)와 보건복지부는 2002년 4월 7일 세계 보건의 날을 맞아 ‘Move for health'라는 구호로 운동의 중요성 및 생활 속의 활기찬 움직임에 대한 중요성을 일깨우기 위해 보건의 날 올해의 주제로 선정하였다. 4월의 이달의 건강 길라잡이에서는 생활 속에서 쉽게 실천할 수 있는 운동, 나에게 맞는 운동에 대하여 알아본다.

• Proceedings of the Korean Society for the Gifted Conference
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• 2003.05a
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• pp.161-166
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• 2003

우리나라 영재교육에 대한 연구들은 대부분 영재아의 개념정의와 판별도구 개발, 영재발굴, 선발 및 그들의 교육에 편중되어 있는 반면 영재아들의 적응, 자기지각, 또래관계등 사회정서발달에 관련된 연구는 거의 이루어지지 못하고 있다 이에 본 연구는 과학영재아동의 개인 및 일상생활에서의 적응수준 및 성별에 따른 적응, 자기지각 및 사회적지지의 차이를 파악하며, 그들의 스트레스에 영향을 미치는 자기지각 및 사회적 지지 수준을 살펴보고 영재아의 사회적 성취나 적응에 도움을 줄 수 있는 방안을 모색하고자 한다. 본 연구의 연구문제는 다음과 같다. 첫째, 과학영재아동과 일반아동의 적응(개인적응, 사회적응, 부적응), 자기지각 및 사회적 지지는 차이가 있는가\ulcorner, 둘째, 과학영재아동의 적응, 자기지각 및 사회적 지지는 성별에 따라 차이가 있는가\ulcorner, 셋째, 과학영재아동의 스트레스에 영향을 미치는 자기지각, 사회적 지지 수준은 어떠한가\ulcorner 본 연구의 대상은 전라북도에 위치한 중학교 1학년 100명의 아동이며, 이들은 교사추천 및 전북대학교 과학영재연구소의 과학과 수학시험을 통해 선발된 과학 영재아동이다. 설문결과 불성실한 응답자를 제외한 총 39명(남아 59명, 여아 30명)이 최종 연구대상이 되었다. 본 연구의 측정도구로 아동의 적응능력검사도구는 한국교육평가센터(KETC)에서 1998년 개발하여 표준화과정을 마친 종합적응능력검사를 사용하였으며, 개인적응영역(자아개념 12문항, 성취동기 10문항, 자기기획 15문항), 사회적응영역(사교성 15문항, 애착 9문항, 사회적 긍정성 10문항), 부적응영역(스트레스 20문항, 욕구좌절 10문항, 편견 12문항) 총 113문항으로 구성되어 있다. 아동의 자기지각검사도구는 Harter(1985)의 Self-Perception Profile이며, 학업역량, 사회적역량, 운동역량, 신체외모역량, 행동품행역량, 자기가치감 각각 6문항씩 총36문항으로 구성되어 있다. 아동의 사회적 지지검사도구는 한미현(1996)이 제작한 척도를 사용하였으며 부모지지, 교사지지, 학교친구지지, 친한 친구지지 각각 6문항씩 총 24문항으로 구성되어 있다.

• Journal of Life Science
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• v.17 no.3 s.83
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• pp.368-374
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• 2007

The purpose of this study was to investigate the effects of different type of triglycerides (MCT & LCT) on weight, survival time, energy substrate (FFA, TG, pyruvate, lactate), insulin and lipase in the trained rats. Fifty-four Sprague-Dawley rats were divided into 3 groups: control group (CG, n=18), MCT supplement group (MG, n=18), and LCT supplement group (LG, n=18). They also were divided into 3 periods: trained resting (R, n=6) and trained & exercise load (E, n=6), and survival time test was performed to know the supplemented effects. Body weight of all animals was checked every week, MCT group and LCT group received supplementary MCT and LCT orally and preliminary swimming training for 6 days before the start of main experiment. All animals received 15-minute swimming training 5 times during first week of experiment, and swimming training time was increased 15 minutes every week until it reached 90 minutes at last 9th week. After last swimming training, animals were fasted for 12 hours and blood samples were taken from abdominal aorta in the Department of Animal Medicine at the D university Animal Center. Among the CGE, MGE, and LGE groups, the MGE had the greatest increase in physical performance time. In the FFA levels, there was significant differences(p<.05) in CG, MG and LG groups, and also there was major difference of FFA levels in the MG and LG. In the lipase levels, there was signifi.ant differences (p<.05) in CG, MG and LG groups. MG was the greatest than the other groups. In the insulin hormone levels, there was the great differences (p<.05) in LG compare to CG groups, whereas there was no significant difference in the CG and MG. In conclusion, these results suggest that regular prolonged physical training with MCT supplementation, improves exercise performance time through the increase of energy substrate utilization, lipase activity and FFA levels, irrespective of insulin hormone responses.

• PNF and Movement
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• v.3 no.1
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• pp.55-66
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• 2005

목적 : 본 연구는 경미한 경부 통증을 가진 대상자의 경부 운동감각과 경부 통증과 기능에 대하여 조사하였다. 방법 : 본 연구의 대상자는 자발적으로 참여한 81명의 (나이 18-30세, 평균 23.2) 건강한 대학생으로 구성되었으며, 측정은 경부운동감각과 통증 및 기능에 대하여 측정하였다. 경부운동감각은 편안히 앉은 자세에서, 경부 후인과 좌우 회전의 중간 관절 범위에서 대상자의 두부에 착용하지 않는 기구를 사용하여 측정하였다. 경부 통증과 기능은 가장 흔히 쓰이는 4가지 설문지를 한국어로 번역하고 문화적으로 적응하는 과정을 거쳐 사용하였다. 결과 : 대상자들을 경부 통증 빈도에 따라 세 집단으로 (통증 없음, 월별, 주별) 구분하였다. 각 집단간에는 4가지 설문지로 조사한 경부통증과 기능에는 차이를 보이지 않았으나, 경부운동감각은 통증 빈도가 높을수록 더 민감하게 나타났다 결론 : 경부 운동감각은 편안히 앉은 자세에서 경부 후인과 좌 우회전의 중간 관절범위에서 측정하였으며, 경미한 경부 통증 빈도가 높을수록 경부 운동감각은 더 민감하게 나타났다.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2003.05a
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• pp.307-310
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• 2003

본 논문에서는 대표적인 비선형 동특성을 가지는 실제 헬리콥터의 회전 띤 자세 운동을 근사화한 모형 헬리콥터의 시스템을 소개하고 이 시스템의 정지 자세 제어를 목표로 직접 적응 웨이브렛 신경회로망 제어기를 다음의 과정에 의해 만든다. 우선 상태 공간에 적용할 웨이브렛 기준 함수를 정의하고 나서 제어기로 들어오는 입력 값의 대략적인 범위와 특성을 파악해서 웨이브렛 이론에 근거해 신축(dilation)과 이동(traslation) 변수 값을 선택하여 초기 적응 웨이브렛 신경회로망 제어기를 건설한다. 마지막으로 시스템의 안정화 제어를 위하여 선택, 교배, 돌연변이의 진화연산자에 의해 일시에 최적의 구조와 결합가중치로 진화시켜 가는 새로운 형태의 ENNC를 제안하여 연결 가중치(weight)를 조정한다. 이 직접 적응 웨이브렛 신경회로망 제어기를 비선형 시스템인 모형 헬리콥터 시뮬레이터에 적용하여 제안한 제어기의 견실성 및 그 우수성을 입증하고자 한다.