• Title/Summary/Keyword: 용해도 상수.

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Fabrication and application of cell-based microfluidic chip for eye-irritation test of chemicals (화학 물질의 안자극 시험용 세포 기반 미세유체 칩의 제작 및 응용)

  • Cho, Sujin;Rhee, Seog Woo
    • Analytical Science and Technology
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    • v.34 no.6
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    • pp.275-283
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    • 2021
  • This study presents the development of cell-based microfluidic chips for the performance of acute eye irritation tests due to chemicals and examined some of their applications. Microfluidic chips were fabricated by photolithography and soft lithography, and they had three compartments with different areas for cell culture. Rabbit corneal epithelial cells were used for the eye irritation test. The death of cells cultured inside the chip was monitored at regular time intervals after treatment with an aqueous solution of chemicals, and the cell death rate constants were calculated based on the viability curve. The performance of the microfluidic chip was verified by examining the effects of cell-cell junctions, cell-substrate adhesion, and initial cell numbers compared to cell death rates. Eye irritation tests were performed at various concentrations of an aqueous solution of sodium dodecyl sulfate (SDS), a standard substance for the eye irritant test. The cells were exposed to the SDS aqueous solution for 300 s, and the resulting eye irritation was assessed by cell viability. Finally, the equation for calculating the toxicity score (TS) was derived based on the weighting factor for each compartment in the chip. The cell-based microfluidic chip developed in this study may be used for eye irritation tests from chemicals used in cosmetics and pharmaceuticals.

Effect of Seeding Method and Flooding Time After Seeding on Seedling Establishment and Growth in Direct Drill Seeding Culture of Rice in Puddled Soil (벼 무논골뿌림 재배에서 파종방법과 파종후 담수시기가 입모 및 생육에 미치는 영향)

  • Kim, Sang-Su;Choi, Min-Gyu;Seok, Soon-Jong;Lee, Seon-Yong;Park, Keun-Yong;Cho, Dong-Sam
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.39 no.5
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    • pp.495-501
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    • 1994
  • This experiment was carried out to investigate the proper seeding methed for direct seeding culture of rice in puddled soil at ill-drained paddy field. Mangeumbyeo was seeded on May 11 with drill seeder attached to cultivater, dibbling seeder attached to transplanter and power dust blower. And to determine the proper flooding time after seeding, Mangeumbyeo was seeded on May 7 and June 1 with drill seeder. Emergence ratio wasn't significantly different between drill seeder seeding and dibbling seeder seeding but emergence was very low with power dust blower. Working hour for seeding was shortened in the order of power dust blower, drill seeder and dibbling seeder, and these seeding methods saved the working hour remarkably compared with machine transplanting of infant seedling by omitting the procedures of raising seedling and transplanting. Lodging occurred slightly in all seeding methods. However, yield wasn't significantly different between machine transplanting of infant seeding and direct seeding culture in puddled soil except power dust blower. When field was flooded on seeding date, the emergence period was shortened, emergence ratio was increased and weed occurrence was decreased. Yield was highest when flooding was done on seeding date as the number of panicle per m$^2$ and the number of spikelets per m$^2$ were higher than any other flooding time.

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Porosity Evaluation of Offshore Soft Soils by Electrical Resistivity Cone Probe (전기비저항 콘 프로브를 이용한 해안 연악 지반의 간극률 산정)

  • Kim, Joon-Han;Yoon, Hyung-Koo;Choi, Yong-Kyu;Lee, Jong-Sub
    • Journal of the Korean Geotechnical Society
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    • v.25 no.2
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    • pp.45-54
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    • 2009
  • The electrical characteristics of soils have been used for investigating soil properties. The purpose of this study is the development and application of the electrical resistivity cone probe (ERCP) for the evelation of the porosity in the field with high precision. The shape of the probe tip is a cone shape to minimize the disturbance during penetration. In addition, the four terminal pair configuration is adopted to minimize the electrical interference. The electrical resistances are continuously measured during penetration of the ERCP using penetration rigs with 0.33 mm/sec penetration rate at Incheon and Busan sites. With the measured resistance profile and electrical resisivity of electrolyte of undisturbed samples, soil porosity profiles are obtained by using Archie's law. The empirical coefficients for the Archie's law are obtained based on the electrolyte extracted from the undisturbed samples. The estimated porosity profiles show similar trends to those of in-situ penetration tests such as SPT, CPT, and DMT. This study suggests that the ERCP may be an effective tool for the porosity estimation in the field with minimum disturbance.

Life Cycle Environmental Analysis of Valuable Metal (Ag) Recovery Process in Plating Waste Water (폐도금액내 유가금속(Ag) 회수 공정에 대한 전과정 환경성 분석)

  • Da Yeon Kim;Seong You Lee;Yong Woo Hwang;Taek Kwan Kwon
    • Resources Recycling
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    • v.32 no.2
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    • pp.12-18
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    • 2023
  • In 2018, the demand for silver (referred to as Ag) in the electrical and electronics sector was 249 million tons. The demand stood at 81 million tons in the solar module production sector. Currently, due to the rapid increase in solar module installation, the demand for silver is increasing drastically in Korea. However, Korea's natural metal resources and reserves are insufficient in comparison to their consumption, and the domestic silver ore self-sufficiency rate was as low as 2.2% as of 2021. This implies that a recycling technology is necessary to recover valuable metal resources contained in the waste plating solution generated in the metal industry. Therefore, this study compared and analyzed, the results of the impact evaluation through life cycle assessment according to an improvement in the process of recovery of valuable metals in the waste plating solution. The process improvement resulted in reducing GWP (Global Warming Potential) and ADP(Abiotic Depletion Potential) by 50% and 67%, respectively. The GWP of electricity and industrial water was reduced by 98% and 93%, respectively, which significantly contributed to the minimization of energy and water consumption. Thus, the improvement in recycling technology has a high potential to reduce chemical and energy use and improve resource productivity in the urban mining industry.

A parallel plate viscometer for blood viscosity measurement (혈액점도 측정용 평행판 점도계)

  • Donggil Seo;Kyung Hyun Ahn;Jihoon Kang;Sangsoo Park
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.4
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    • pp.331-335
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    • 2023
  • As the viscosity of the blood increases, the blood becomes more sticky and difficult to flow, so the possibility of thrombosis increases and the probability of ischemic cerebral infarction increases. The importance of measuring blood viscosity has recently been emphasized for the prevention of circulatory system diseases, and the need for a viscometer capable of easily and accurately measuring blood viscosity has emerged. In this study, the measured values of a viscosity standard solution and an artificial blood by a parallel-plate viscometer ARS-Medi were compared with the those by Ares-G2 of TA instrument, which is internationally recognized for its accuracy and reliability. The viscosity of N44 standard solution, which is a Newtonian solution, was almost perfectly matched between the two instruments at all shear rates. In the case of an artificial blood, which is a non-Newtonian solution, the measured values between the two instruments showed a difference of about 10% at the lowest shear rate 1 rad/s; however, at a clinically significant shear rate of 10 rad/s or higher, the measured values between them were consistent within the error range. We expect that ARS-Medi, a newly developed parallel-plate viscometer for blood, using disposable plates, will be very useful in clinical practice as it improves the convenience and hygiene of blood viscosity measurement.

Current status of sweetpotato genomics research (고구마 유전체 연구현황 및 전망)

  • Yoon, Ung-Han;Jeong, Jae Cheol;Kwak, Sang-Soo;Yang, Jung-Wook;Kim, Tae-Ho;Lee, Hyeong-Un;Nam, Sang-Sik;Hahn, Jang-Ho
    • Journal of Plant Biotechnology
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    • v.42 no.3
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    • pp.161-167
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    • 2015
  • Sweetpotato [Ipomoea batatas (L.) Lam] grows well in harsh environmental conditions, and is cultivated as one of the top seven food crops in the world. Recently, sweetpotato is drawing interest from people as a healthy food because it is high in dietary fiber, vitamins, carotenoids and overall nutrition value. However, few studies have been conducted on sweetpotato genome sequencing in spite of its importance. This review is aimed at increasing the efficiency of sweetpotato genome sequencing research as well as establishing a base for gene utilization in order to control useful traits. Recently, animal and plant genome sequencing projects increased significantly. However, sweetpotato genome sequencing has not been performed due to polyploidy and heterogeneity problems in its genome. Meanwhile research on its transcriptome has been conducted actively. Recently, a draft of the diploid sweetpotato genome was reported in 2015 by Japanese researchers. In addition, the Korea-China-Japan Trilateral Research Association of Sweetpotato (TRAS) has conducted research on gene map construction and genome sequencing of the hexaploid sweetpotato Xushu 18 since 2014. The Bill & Melinda Gates Foundation launched the 'sweetpotato genomic sequencing to develop genomic tools for Sub-Sahara Africa breeding program'. The chloroplast genome sequence acquired during sweetpotato genome sequencing is used in evolutionary analyses. In this review, the trend of research in the sweetpotato genome sequencing was analyzed. Research trend analysis like this will provide researchers working toward sweetpotato productivity and nutrient improvement with information on the status of sweetpotato genome research. This will contribute to solving world food, energy and environmental problems.

Effect of Acrylic Acid on the Physical Properties of UV-cured Coating Films for Metal Coating (금속코팅용 광경화 코팅필름의 물성에 대한 아크릴산(Acrylic acid)의 영향)

  • Seo, Jong-Chul;Choi, Jun-Suk;Jang, Eui-Sung;Seo, Kwang-Won;Han, Hak-Soo
    • Korean Chemical Engineering Research
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    • v.49 no.1
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    • pp.75-82
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    • 2011
  • Five different composition UV-cured poly(urethane acrylate-co-acrylic acid) (PU-co-AA) films have been prepared by reacting isophorone diisocyanate(IPDI), polycaprolactone triol(PCLT), 2-hydroxyethyl acrylate(HEA), and different weight ratio trimethylolpropane triacrylate(TMPTA) and acrylic acid(AA) as diluents, and characterized using a Fourier transform infrared spectroscopy(FT-IR). The adhesion properties onto the stainless steel, morphology, mechanical hardness, and electrical property of UV-cured PU-co-AA films were investigated as a function of acrylic acid(AA) content. All the PU-co-AA films are structure-less and the molecular ordering and packing density decreased with increasing content of AA due to the flexible structure and -COOH side chains in AA. The crosscut test showed that PU-co-AA films without AA and with low content of AA showed 0% adhesion(0B) and the adhesion of PU-co-AA films in the range of 40-50% AA increased dramatically as the content of AA increases. The pull-off measurements showed that the adhesion force of PU-co-AA films to stainless steel substrate varied from 6 to 31 kgf /$cm^2$ and increased linearly with increasing AA content. The mechanical hardness also decreased as the content of AA increases. This may come from relatively linear and flexible structure in AA and low crystallinity in PU-co-AA films with higher content of AA. The higher AA-containing PU-co-AA films showed higher dielectric constant due to the increase of polarization by introducing AA monomer. In conclusion, the physical properties of UV-cured PU-co-AA films are strongly dependent upon the content of AA and the incorporation of AA in polyurethane acrylate is very useful way to increase the adhesion strength of UV-curable polymers on the stainless steel substrate.

Change of Nutrition Loss of Long-term Application with Different Organic Material Sources in Upland Soil (유기물원이 다른 퇴비연용 밭토양에서 양분유실량 변화)

  • Kim, Jong-Gu;Lee, Kyeong-Bo;Kim, Jae-Duk;Han, Sang-Su;Kim, Seong-Jo
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.6
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    • pp.432-445
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    • 2000
  • The objective of this study was to determine the effects of various kinds of composts on the change of nutrition loss in upland soils. Field experiments were conducted in the loam and sandy loam soils, while the clay loam and sandy loam soils were used for laboratory experiments. Various kinds of composts such as poultry manure compost(PMC), cow manure compost(CMC), human excrement sludge(HES), and food industrial sludge compost(FISC) were applied annually at rates of 0, 40, and $80mg\;ha^{-1}$ to soils grown with soybean and maize plants for 4 years during 1994 to 1997. The results of this study were as follows : The loss of nutrients in the form of cation and anion by run-off water increased with the increase of compost application rate. Compared with bare soils, maize cultivation decreased the nutrient loss by run-off from soils by 43% in anionic form and 32% in cationic form. Amount of cation loss were ordered $K^+$ > $Ca^{2+}$ > $Na^+$ > $Mg^{2+}$ > $NH_4{^+} $ and that of anion loss were ordered $SO_4{^{2-}}$ > $NO_3{^-}$ > $Cl^-$ > $PO_4{^{3-}}$. Nutrient loss of sand loam soil in the cation and anion by percolation water increased 1.7 times compared with loam soil. $NO_3{^-}-N$ contents in percolated water were high at the initial stage after compost application, and the amounts were higher in sandy loam soil than loam soil. The maize cultivation also decreased the $NO_3{^-}-N$ contents in percolated water by 82% in loam soil, and 58% in sand loam soil. Soil pH of composts determined by laboratory incubation test increased pH 6.1~6.8 application with poultry and cow manure compost but application with human excrement sludge decreased pH 4.5~4.7. Soil EC were increased initially composts application and decreased up to 2 weeks, thereafter kept a certain level. Nitrogen mineralization rates of composts determined by laboratory incubation test at $25^{\circ}C$ were 39~76% in sandy loam soil, and 16~48% in clay loam soil.

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Performance Prediction for an Adaptive Optics System Using Two Analysis Methods: Statistical Analysis and Computational Simulation (통계분석 및 전산모사 기법을 이용한 적응광학 시스템 성능 예측)

  • Han, Seok Gi;Joo, Ji Yong;Lee, Jun Ho;Park, Sang Yeong;Kim, Young Soo;Jung, Yong Suk;Jung, Do Hwan;Huh, Joon;Lee, Kihun
    • Korean Journal of Optics and Photonics
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    • v.33 no.4
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    • pp.167-176
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    • 2022
  • Adaptive optics (AO) systems compensate for atmospheric disturbance, especially phase distortion, by introducing counter-wavefront deformation calculated from real-time wavefront sensing or prediction. Because AO system implementations are time-consuming and costly, it is highly desirable to estimate the system's performance during the development of the AO system or its parts. Among several techniques, we mostly apply statistical analysis, computational simulation, and optical-bench tests. Statistical analysis estimates performance based on the sum of performance variances due to all design parameters, but ignores any correlation between them. Computational simulation models every part of an adaptive optics system, including atmospheric disturbance and a closed loop between wavefront sensor and deformable mirror, as close as possible to reality, but there are still some differences between simulation models and reality. The optical-bench test implements an almost identical AO system on an optical bench, to confirm the predictions of the previous methods. We are currently developing an AO system for a 1.6-m ground telescope using a deformable mirror that was recently developed in South Korea. This paper reports the results of the statistical analysis and computer simulation for the system's design and confirmation. For the analysis, we apply the Strehl ratio as the performance criterion, and the median seeing conditions at the Bohyun observatory in Korea. The statistical analysis predicts a Strehl ratio of 0.31. The simulation method similarly reports a slightly larger value of 0.32. During the study, the simulation method exhibits run-to-run variation due to the random nature of atmospheric disturbance, which converges when the simulation time is longer than 0.9 seconds, i.e., approximately 240 times the critical time constant of the applied atmospheric disturbance.

Magnetic Properties of $ThMn_{12}-type$$NdFe_{10.7}Ti_{1.2}Mo_{0.1}$>$Ti_{1.2}Mo_{0.1}$ ($ThMn_{12}$$NdFe_{10.7}Ti_{1.2}Mo_{0.1}$의 미세구조 및 자기적 성질 연구)

  • 안성용;이승화;김철성;김윤배;김창석
    • Journal of the Korean Magnetics Society
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    • v.7 no.2
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    • pp.90-96
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    • 1997
  • We have studied crystallographic and magnetic properties of $NdFe_{10.7}Ti_ {1.2}Mo_{0.1}$ by Mossbauer spectroscopy, X-ray diffraction and vibrating sample magnetometer (VSM). The alloys were prepared by arc-melting under an argon atmosphere. The $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ has pure a single phase, whereas $NdFe_{10.7}Ti_{1.3}$ contains some $\alpha$-Fe, conformed with X-ray diffractometry and Mossbauer measurements. The $NdFe_{10.7}Ti_ {1.2}Mo_{0.1}$ has a $ThMn_{12}-type$ tetragonal structure with $a_0=8.637{\AA}$ and $c_0=4.807{\AA}$. The Curie temperature ($T_c$) is 600 K from the result of Mossbauer measurement performed at various temperatures ranging from 13 to 800 K. Each spectrum of below $T_c$ is fitted with five subspectra of Fe sites in the structure ($8i_1, 8i_2, 8j_2, 8j_1, 8f$). The area fractions of the subspectra at room temperature are 12.3%, 14.0%, 21.0% 11.8%, 40.9%, respectively. Magnetic hyperfine fields for the Fe sites decrease in the order, $H_{hf}(8i)>H_{hf}(8j)>H_{hf}(8f)$. The abrupt changes in the magnetic hyperfine field, an magnetic moment observed at about 160 K in $NdFe_ {10.7} Ti_{1.2}Mo_{0.1}$ are attributed to spin reorientations. The average hyperfine field of the $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ shows a temperature dependence of $[H_{hf}(T)-H_{hf}(0)]/H_{hf}(0)=-0.34(T/T_C)^{3/2}-0.14(T/T_C)^{5/2}$ for $T/T_c<0.7$, indicative of spin wave excitation. The Debye temperatures of $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ is found to be Θ=340$\pm$5 K.

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