• Title/Summary/Keyword: 외부성과

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NF-${\kappa}$ B Activation and Cyclooxygenase-2 Expression Induced by Toll-Like Receptor Agonists can be Suppressed by Isoliquiritigenin (Isoliquiritigenin의 toll-like receptor agonists에 의해서 유도된 NF-${\kappa}$B 활성화와 cyclooxygenase-2 발현 억제)

  • Park, Se-Jeong;Yang, Seung-Ju;Youn, Hyung-Sun
    • Korean Journal of Food Science and Technology
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    • v.41 no.2
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    • pp.220-224
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    • 2009
  • Toll-like receptors(TLRs) are pattern recognition receptors(PRRs) that recognize pathogen-associated molecular patterns(PAMPs) and regulate the activation of innate immunity. All TLR signaling pathways culminate in the activation of NF-${\kappa}$B, leading to the induction of inflammatory gene products such as COX-2. Licorice (Glycyrrhiza uralensis) has been used for centuries as an herbal medicine. Isoliquiritigenin(ILG), a simple chalcone-type flavonoid, is an active component present in licorice and has been used to treat many chronic diseases. However, the mechanism as to how ILG mediates health effects is still largely unknown. In the present report, we present biochemical evidence that ILG inhibits the NF-${\kappa}$B activation induced by TLR agonists and the overexpression of downstream signaling components of TLRs, MyD88, IKK${\beta}$, and p65. ILG also inhibits TLR agonists-induced COX-2 expression. These results suggest that anti-inflammatory effects of ILG are caused by modulation of the immune responses regulated by TLR signaling pathways.

LES Investigation on The Cryogenic Nitrogen Injection of Swirl Injector Under Supercritical Envionment (초임계 환경에서 와류형 분사기의 극저온 질소 분사 LES 연구)

  • Kang, JeongSeok;Heo, JunYoung;Sung, Hong-Gye;Yoon, YoungBin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.44 no.4
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    • pp.343-351
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    • 2016
  • Cryogenic spray characteristics of a nitrogen swirl injector operating in supercritical environment have been numerically investigated. By comparing the equation of states(EOS) used for supercritical condition, SRK EOS was applied to predict the nitrogen thermodynamic property under supercritical environment. A Chung's method was implemented for the calculation of viscosity and conductivity and Takahashi's correlation based on Fuller's Theorem was implemented for the calculation of diffusion coefficient. By injecting the nitrogen with 5 bar differential pressure into 50 bar chamber filled with nitrogen, numerical simulation has been conducted. The dynamic Smagorinsky sub-grid scale (SGS) model has been compared with the algebraic Smagorinsky SGS model using FFT frequency analysis. The instability at the liquid film and gas core inside injector and the propagation of pressure oscillation into the injector has been investigated. The spreading angle of swirl injector obtained by numerical calculation has been validated with experimental result.

Analysis on Research Trends and Factor of Success to Communities of Practice in Korea (국내의 실천공동체(Communities of Practice)연구 동향 분석 및 성공 요인 분석)

  • Lee, Eun-Chul;Choi, Moon-Sun
    • The Journal of the Korea Contents Association
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    • v.15 no.3
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    • pp.438-447
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    • 2015
  • When communities of practice(CoP) was mostly informal, has been formulated. Because Knowledge management(KM) was emphasized in the business sector. So it increase interest in the COP. Since the early 2000s, the research interest has thus far grown. At a point in time has the subject, CoP, been researched for ten years, it is significant to review the literatures, the main topics as well as critical factors on the subject. In this study, the trends in the relevant researches and the performance factors from the previous studies are examined. The references for this study are limited to the authorized scholarly and scientific journals. The results therethrough processed show that total 37 researches were conducted between the year 2000 and 2012. These could be classified by the research methods as 16 case studies, 11 studies using CoP as the dependent variable, 4 studies using CoP as an independent variable and 3 theoretical discourses. 7 out of 16 case studies suggest the 14 success factors of CoP; the most influential performance factor is the external community support. 11 studies examined factors influencing the performance of CoP; 13 performance factors were proposed in these studies. The most significant factor influencing the performance of CoP is the team effectiveness.

Analysis of Bar in Coil's Application to Rebar Work (철근공사의 코일철근(Bar in Coil) 적용타당성 분석)

  • Lee, Hyun-Soo;Kim, Jae-Gon;Park, Moon-Seo;Kim, Hyun-Soo;Hwang, Sung-Joo
    • Korean Journal of Construction Engineering and Management
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    • v.13 no.1
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    • pp.106-117
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    • 2012
  • The proportion of rebar factory manufacturing which has been settled down in Korea recently seems to increase because of their strength such as high decreasing rate of rebar loss and manufacturing accuracy and the external factors such as an increase of downtown projects and a decrease of skilled workers. However, factory manufacturing using straight rebars causes a certain amount of rebar loss and an environmental problem including $CO_2$ emissions. To solve these problems, Bar in coil (BIC) has been introduced; however its application is very rare because it has not been produced so far in Korea and manufacturing machines of BIC are very expensive. Also, although BIC's application is expected to expand due to its strengths, few analysis of its application has been conducted. Therefore in this study, analysis of the BIC's characteristics and the influence to the rebar manufacturing industry are conducted for the advancement of rebar work as a basic research. To achieve this, inquiry on the present condition of rebar manufacturing industry in Korea is implemented. Then, the validation of BIC's applications by aspects of industry and the analysis of stakeholders' economical profit and loss are conducted.

Analysis of Key Parameters for Designing the Spent Nuclear Fuel Disposal Container in Korea (사용후핵연료 처분용기 설계를 위한 주요인자 분석)

  • Choi, Jong-Won;Cho, Dong-Keun;Choi, Hui-Ju
    • Journal of Radiation Protection and Research
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    • v.31 no.1
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    • pp.37-46
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    • 2006
  • For the first step to develop a reference disposal container of spent fuel to be used in a deep geological repository, this paper examined safe dimensions of the disposal container on the points of nuclear criticality and radiation safety and mechanical structural safety and provided basic information for dimensioning the container and configuration of the container components, and establishing the favorable and safe disposal conditions. When the safety factor for stress due to the external loads (hydrostatic and swelling pressure) is taken as 2.0, the safe diameter of the filler material to provide enough container strength under the assumed external loads is found to be 112cm with 13cm spacing between inner baskets in PWR container. Also the thickness of the thinner section between the fuel basket and the surface of the cast insert is determined to be 150 mm. Regarding these dimensions of the container, the PWR fuel container is sketched to accommodate 4 square assemblies or 297 CANDU fuel 297 bundles (33 circle tubes x 9 stacks). However the top and bottom parts need to be checked again through the detail radiation shielding analysis with respects to the emplacement position and handling processes of the disposal container.

KSTAR 토카막 플라즈마 가열을 위한 중성 입자빔 입사장치용 이온원 개발 현황

  • Kim, Tae-Seong;Jeong, Seung-Ho;Jang, Du-Hui;Lee, Gwang-Won;In, Sang-Yeol;O, Byeong-Hun;Jang, Dae-Sik;Jin, Jeong-Tae;Song, U-Seop
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.559-559
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    • 2013
  • KSTAR (Korea Superconducting Tokamak Advanced Research) 장치는 차세대 에너지원 중의 하나인 핵융합로를 위한 과학기술 기반을 마련하기 위해 개발된 중형급 토카막 실험장치로서 토카막 운전 영역의 확장과 안정성 확보, 정상상태 운전 도달을 위한 방법 연구, 최적화된 플라즈마 상태와 연속 운전 실현 등을 주요 목표로 하고 있다. 이를 위해 핵융합 반응에 의한 점화조건과 가까운 상태로 플라즈마를 가열해주어야 하며, 토카막 장치의 저항가열 이외에도 외부에서 추가 가열이 반드시 필요하다. 중성 입자빔 입사 장치는 현재 토카막에서 사용되고 있는 가열장치 중 가장 신뢰성있는 추가 가열 장치라 할 수 있으며 한국 원자력연구원에서는 1997년부터 KSTAR 토카막 실험 장치에 사용될 중성 입자빔 입사 장치를 개발해왔었다. 중성빔 입사 장치는 크게 이온원, 진공함, 열량계, 진공 펌프, 중성화 장치, 이온덤프와 전자석으로 이루어져 있으며, 이중 이온원은 중성빔의 성능을 좌우하는 핵심적인 장치라 할 수 있다. 최근 한국원자력연구원에서는 2 MW 중성 입자빔 입사장치용 이온원 개발을 완료하여 KSTAR 토카막 장치에 설치하였으며, 2013년 현재 KSTAR에는 총 두 개의 이온원이 장착되어 최대 약 3 MW 이상의 중수소 중성 입자빔을 입사하여 KSTAR 토카막 실험의 H-mode 달성과 운전 시나리오 연구에 많은 기여를 하고 있다. 한국원자력연구원에서 최초로 개발된 이온원은 미국 TFTR 장치에서 사용되었던 US LPIS (Long Pulse Ion Source)를 기본으로 하여 국내 개발을 수행하였다. 이 온원은 크게 플라즈마를 발생시키는 플라즈마 발생부와 발생된 이온을 인출 및 가속시키는 가속부로 구성되는데, 개발과정에서 가장 먼저 KSTAR의 장주기 운전에 적합하도록 플라즈마 방전부와 가속부의 냉각회로를 요구되는 열부하에 맞게 설계 수정하였다. 그 후 플라즈마 방전부는 방전 시간과 안정성, 플라즈마 밀도의 균일도, 정격 운전, 방전 효율 등을 고려하여 수정 보완하며 개발을 진행하여왔다. 가속부의 경우 국내 제작기술의 한계를 극복하기 위해 빔 인출그리드를 TFTR의 US LPIS 모델의 슬릿형 그리드 타입에서 원형 인출구 타입으로 변경하였으며, 이후 가속 전극의 고전압 내전력 문제, 빔 인출 전류와 전력, 인출 빔의 광학적 질(quality), 빔 인출 시간 동안의 안정성 등을 위해 그리드의 크기와 간격, 모양 등을 변경하여 개발을 수 행하여 왔다. 이 논문은 한국원자력연구원에서 개발이 진행되어 왔던 이온원들을 시간적으로 되짚어 보면서 현재까지의 성과와 문제점, 그리고 앞으로의 개발 방향에 대해 논의하고자 한다.

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Physicochemical Characteristics of Korean Folk Sojues (전통민속소주의 물리화학적 특성)

  • Lee, Dong-Sun;Park, Hye-Seong;Kim, Kun;Lee, Taik-Soo;Noh, Bong-Soo
    • Korean Journal of Food Science and Technology
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    • v.26 no.5
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    • pp.649-654
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    • 1994
  • In order to provide a quality index of Korean folk sojues, physicochemical properties of Korean folk sojues (Andong soju, Moonbaesul, Leekangju, Jindo Hongju, Chebiwon soju, Yethyang (rice) and Yethyang (barley)), Paekrosul, Chinese kaoliangchiews (Moutaichiew, Ergoutoutiu, Chuyehchingchiew, Zhikukaoliangchiew and Paigal), Japanese Senbatanuki shochu and two whiskies were determined. The pH of sojues ($3.43{\sim}5.85$) were mainly influenced by total acidity which was described as acetic acid. The conductivities of Paekrosul and Leekangju showed relatively high value of $246\;and\;122.7{\mu}S/cm$, respectively. Korean folk sojues and Paekrosul showed maximum absorption at 274 or $278{\sim}280nm$ in the spectrometric study. We performed principal components analysis (PCA) of physicochemical properties and spectrometric data to extract representative characteristics and to compare the similarity or the dissimilarity. The PCA plot showed the distinguished cluster of Korean folk sojues comparing with Chinese kaoliangchiew or Paekrosul etc.

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Evaluation of effectiveness of Smart Water City in Korea - Smart Water City project in Paju City, Gyeonggi Province (한국 스마트워터시티의 효과성 평가 - 경기도 파주시 스마트워터시티 사업을 중심으로)

  • Lee, Yookyung;Lee, Seungho
    • Journal of Korea Water Resources Association
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    • v.53 no.spc1
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    • pp.813-826
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    • 2020
  • This study analyzes the effects of the Smart Water City (SWC) project that was introduced from 2014 to 2016 in Paju City, Gyeonggi Province, Korea, focusing on the achievement of the business goals. The SWC is referred to as a city that embraces a healthy water supply system based on Smart Water Management (SWM) that promotes the efficiency of water management by combining Information and Communication Technologies (ICTs) with water and sewerage facilities. In order to evaluate the effectiveness of the SWC project, this study deploys evaluation criteria corresponding to the project objectives, and analyzes the outputs before and after the project. The results show that the SWC has contributed to enhancing water supply services and the reliability and drinking rate of tap water. Specific improvement areas include the rise of average water flow rate and water leakage reduction, the diffusion of water quality monitoring system, and the reduction of floating particle concentration and turbidity in drainage pipes was achieved. These were possible because of specific implementation plans for clear goal setting and achievement and active services for citizens. The data related to water quantity and quality showed improved performance compared to before the introduction of SWMS, which is a positive effect. However, a quantitative analysis of the outputs has limitations in identifying other external factors that have led to the changes. In the future, guidelines for spreading SWC and more comprehensive and specific evaluation indicators for SWC should be prepared, and SWMS should be developed in consideration of the needs of users.

The Influences of Thailand's Import and FDI on Lao PDR's Economic Growth (태국의 수입 및 FDI가 라오스의 경제성장에 미친 영향)

  • Kim, Kyu;Kwon, KiChul
    • The Journal of the Korea Contents Association
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    • v.20 no.1
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    • pp.304-316
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    • 2020
  • Laos is rich in natural resources but lacks the capital to develop them. Partly alleviating the shortage is FDI from neighboring countries, especially Thailand. Not only does this contribute to directly increasing GDP by increasing effective demand, it also has an additional GDP increase effect by expanding Laos' production capacity. Laos' exports mostly consist of mineral resources and electricity. This, too, contributes to an increase in GDP by increasing the effective demand. Thailand accounts for more than 40 percent of Laos' exports. This paper tries to confirm the economic impact on Laos in Thailand through a econometric analysis of Laos' GDP, Laos' exports to Thailand and Thailand's FDI to Laos. It turns out that economic ties with Thailand, including exports to Thailand and Thailand's FDI, play a very important role in Laos' economic growth. Laos recently recorded relatively robust economic growth, but its driving force is weak. That's because Laos' growth engines are very limited and have no resilience to external shocks. Moreover, economic growth has not been linked to an increase in employment because the economy is not diversified and growth in the hydroelectric power sector does not lead to growth in other sectors. Given this, Laos needs to actively take advantage of its geographical proximity to Thailand. It is necessary to create a more active environment for the inflow of FDI in Thailand, to foster resource-based and labor-based manufacturing to take advantage of the Thai market.

Korean Companies' Understanding of Carbon Pricing and Its Influence on Policy Acceptance and Practices (한국 기업의 탄소가격 정책에 대한 이해가 정책 수락 및 대응에 미치는 영향)

  • Suk, Sunhee
    • Environmental and Resource Economics Review
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    • v.26 no.4
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    • pp.577-612
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    • 2017
  • In response to climate change, Korea is attempting to shift the paradigm of energy and climate change policies by introducing carbon pricing based on market mechanisms. While policy adoption is proceeding at a rapid pace, the introduction of carbon pricing has been faced with great opposition from industry. This study measures to what extent Korean companies understand and accept carbon pricing, using data from a questionnaire survey covering energy consuming companies in 2012, when discussions between the government and such companies about the introduction of a domestic emission trading system were active. It further identifies how preparations and practices for carbon and energy management of companies correlate with their policy understanding and acceptance. The analysis results show that the surveyed companies indicate moderate understanding of, as well as resistance to carbon pricing policies, while appreciating the economic incentives and accepting the mandatory regulations in this phase. Companies' understanding is more related to characteristics, i.e., sector, size, etc. than external pressures. This study found that the extent to which companies understand policy is the essential factor in their policy acceptance and related practices. In particular, understanding of carbon policy significantly influences their managerial practices and voluntary activities for carbon and energy practices. This study substantiates the correlation between the level of policy understanding of a company and its carbon and energy practices - something that all countries seeking to introduce carbon pricing in response to climate change should consider prior to policy actually being implemented; in other words, enhancing the understanding of major policy subjects of the new instrument is a key policy strategy that should be elaborated as it will lead to better performance of companies and smoother policy implementation.