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Induction Chemotherapy Followed by Radiotherapy for Stage IV Hypopharyngeal Cancer (4기 병기 하인두암에서 선행 항암화학요법후 방사선치료)

  • Kang Ki Mun;Chai Gyu Young;Kim Jin Pyeong;Lee Won Seop
    • Radiation Oncology Journal
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    • v.22 no.4
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    • pp.247-253
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    • 2004
  • Purpose: Hypopharyngeal cancer is diagnosed at the advanced stage in most cases, which the prognosis known to be poor. Thus, the efficacy of induction chemotherapy followed by radiotherapy, with regards to the response and survival rate for stage IV hypopharyngeal cancer patients, was examined. Materials and Methods: From July 1998 to February 2000, 18 cases were diagnosedas AJCC stage IV hypopharyngeal cancer without distant metastasis. These patients were treated with induction chemotherapy followed by radiotherapy, and the results retrospectively analyzed. The regimen of the induction chemotherapy was the 5-FU and cisplatincombination, at 3-week intervals for, 2 cycles. The total radiation dose for the primary lesion and metastatic lymph nodes was $68.4\~72.0$Gy (median: 70.2 Gy). Results: The: The median follow up period was 28 months, ranging from 7 to 99 months. The 3-year overall survival and disease-free survival rate were 41.7 and $31.1\%$, respectively. In 6 cases ($33.3\%$), conservation of the larynx for over 3 years was possible. After the induction chemotherapy there were 16 partial responses ($88.8\%$), 1 complete response and 1 with no response ($5.6\%$ each), therefore, 17 of the 18 cases ($94.6\%$) showed responses. After the completion of the induction chemotherapy and radiotherapy, a complete response was noted in 13 cases ($72.2\%$), a partial response in 5 ($27.8\%$), with an overall response rate of $100\%$. In the analysis of the prognostic factors influencing the survival rate, the 3-year and disease-free survival rates for the complete and partial response groups were 43.1, and $20.0\%$, and 39.6, and $20.0\%$, respectively (p=0.0003, p=0.002). Only the final response after treatment completion was statistically significant. Conclusion: For stage IV hypopharyngeal cancer, induction chemotherapy followed by radiotherapy was an effective treatment, with no severe side effects.

Choriocarcinorma in the Pulmonary Artery Diagnosed and Treated by Emergency Pulmonary Embolectomy (응급 페동맥 색전 제거술로 진단 및 치유된 폐동맥내 융모막 암종)

  • 조봉균;김종인;이해영;박성달;김송명;김영옥
    • Journal of Chest Surgery
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    • v.36 no.7
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    • pp.531-534
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    • 2003
  • A 43-year-old woman who had had an invasive mole 5 years previously required emergent pulmonary embolectomy under cardiopulmonary bypass. Curative resection was impossible because the tumor invaded the right main pulmonary artery and left lower pulmonary artery. The pathologic diagnosis made by the tumor emboli specimens was choriocarcinoma. The patient received post-operative chemotherapy over a 6-month period and had complete remission. Although rare, choriocarcinoma should be considered in the differential diagnosis of fertile women presented with pulmonary embolism.

Blockchain Beyond Bitcoin (비트코인 후 블록체인)

  • Hong, S.Y.;Cho, S.R.;Kim, S.H.
    • Electronics and Telecommunications Trends
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    • v.32 no.1
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    • pp.72-81
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    • 2017
  • 2008년, Satoshi Nakamoto라는 가명을 쓰는 신원미상의 사람(들) 혹은 단체가 비트코인을 소개하였다. 그 이후, 현재 비트코인의 총액은 10억달러 이상에 달한다. 비트코인을 지탱하는 기술인 블록체인에 의해 이론적으로 비트코인은 거의 조작이 불가능하며 거의 영구적으로 기록에 남게 된다. 이 획기적인 기술로 인해 비트코인 이 후 약 700개가 넘는 암호화폐가 생겨났으며, 암호화폐뿐만이 아닌 금융권/비금융권, 정부기관 등 많은 도메인에서 블록체인 기술이 도입되어 가고 있다. 비트코인 이후 가장 대표적인 블록체인 기반의 프로젝트로는 튜링 완전한 컴퓨팅 기능이 있는 이더리움이 있다. 이 튜링 완전한 컴퓨팅 기능으로 인해 이더리움 상에서 투명하게 데이터 저장 및 프로그램 실행을 할 수 있다. 이로 인해 이더리움을 이용한 많은 혁신적인 이용 사례가 생겨났다. 본고에서는 비트코인 후 블록체인의 기술을 이더리움 중심으로 소개하며 해결해야 할 기술적 이슈들과 동향에 관해 분석한다. 그리고 현재 이더리움 외에 개발되어오는 블록체인에 대해 간략히 살펴본다.

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Carcinoma of the Uterine Cervix Treated with External Beam Irradiation Alone (자궁경부암의 외부방사선 치료 성적)

  • Kim, Mi-Sook;Ha, Sung-Whan
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.363-367
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    • 1993
  • A retrospective analysis was peformed on 42 patients with carcinoma of the uterine cervix who were treated with external beam (EB) radiation therapy alone at the Department of Therapeutic Radiology, Seoul National University Hospital from March 1979 to December 1988. After whole pelvic field irradiation of 50Gy, all the patients received additional booster dose of 12-22Gy to the primary tumor Thirty one received EB radiotherapy alone because of poor geometry for intracavitary application,5 because of medical problems and 6 because of other reasons. Five year locoregional control rate and five year survival rate were $34.5\%\;and\;35.4\%,$ respectively. Five year survivals were $66.7\%,\;36.4%,\;32.8\%\;and\;25.0\%$ for stage IIA, IIB, IIIB and IVA, respectively. The response one month after treatment well correlated with prognosis. The incidence of grade 2 and 3 complication was $12\%\;and\;10\%,$ respectively. There was tendency of increased complication with advanced stage.

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식량증산/도열병의 발생동향과 방제대책 - 예찰정보등 참고로 조기방제에 주력

  • 이경용
    • The Bimonthly Magazine for Agrochemicals and Plant Protection
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    • v.7 no.4
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    • pp.88-96
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    • 1986
  • 도열병은 벼농사에 발생하는 40여종의 병해중 가장 피해를 많이 주는 무서운 병으로 발생의 역사가 다른 병해에 비해 길고 많은 연구가들이 내병성품종 육성과 농약등에 관해 시험연구를 계속 실시하고 있으며 농민들이 적극방제를 해도 아직까지 완전해결을 못보고 매년 피해를 보고 있다. 특히 ''60$\~$''70년대 중반기까지는 일반계품종에서 도열병이 많이 발생되었으나 ''78년에는 통일계(다수계)품종에서 피해가 많이 나타났고 ''80년에는 냉해로 인한 도열병 피해가 많았으며 그 후에도 국지적으로 상습지, 사질답, 방제소홀답, 과비답에서 피해가 나타나고 있다.

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Agglomeration Economies, Trade, And System of Cities : A General Equilibrium Approach

  • 권영각
    • Journal of Korean Society of Transportation
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    • v.6 no.2
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    • pp.57-82
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    • 1988
  • 본 연구는 도시규모 결정에 관해 수요 또는 공급측면만을 중시하는 재래식 접근 방 법을 통합, 개선하는 일반균형의 모형을 제시하고 이에 따라 국가 도시규모체계의 효율성을 이해하는데 그 목적이 있다. 이 모형의 주요한 요소는 도시집적이익 및 불이익, 산업구조 그 리고 도시간 자원이동 및 무역을 통한 상호의존성 등이다. 엄밀한 이론적, 절대적 적정 도시 규모체계는 모든 도시가 완전자립 하에 단위도시 적정규모를 이루어 동일규모일 때 가능하 며 시민의 복지가 극대화된다. 그러나 실제 인적, 물적 이동성이 완벽하지 않은 현실 하에서 는 도시규모간 위계성이 생기게 되며 이는 도시간 무역을 가능케하여 상대적 도시규모의 적 정성을 대변해 준다.

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ISO/IEC JTC 1 SC 27 암호기술 국제표준화 동향

  • Daesung Kwon
    • Review of KIISC
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    • v.33 no.4
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    • pp.103-109
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    • 2023
  • 암호기술 국제표준화는 각국의 국가표준기구들이 가입된 ISO/IEC의 JTC 1 산하 SC 27 내 WG(Working Group) 2에서 진행되고 있다. 현재 70여 편의 암호기술 표준이 제정되어 있으며, 최근에는 양자컴퓨터 위협에 대응하기 위한 양자내성 공개키암호와 전자서명, 데이터 보안에 활용할 수 있는 완전동형암호 및 다자간 안전계산의 표준화가 주를 이루고 있다, 본 고에서는 전체적인 표준화 현황을 간략하게 살펴보고, 최신 이슈가 되고 있는 표준화 현황에 관해 설명한다.

The Result of Combined Modality Treatment for Non-Hodgkin's Lymphoma of Head and Neck (두경부 악성 임파종에 대한 병용치료의 결과)

  • Kim Jae Cheol;Kim Sang Bo;Ryu Samuel;Park In Kyu
    • Radiation Oncology Journal
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    • v.8 no.2
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    • pp.255-260
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    • 1990
  • From April 1985 to September 1989, 26 patients with stage I and II non-Hodgkin's lymphoma of unfavorable histology localized in head and neck region were treated with combined modality (combination chemotherapy plus radiotherapy) at the Department of Therapeutic Radiology in Kyungpook National University Hospital. Of the 26 patients, 23 showed complete response and 3 partial response. Between these two groups there were no statistical differences according to the variables. Three-year survival and disease-free survival rate were $62.4{\%}$ and $65.2{\%}$, respectively. Unilateral involvement of neck node (p<0.05), radiation dose over 5000 cGy (p<0.01), and 6 or more cycles chemotherapy (p=0.06) had a favorable effect on 3-year survival rate. There were 8 recurrences including 3 partial responders, 1 local failure, 1 distant failure, 1 contiguous failure, and 2 simultaneous local and distant failure. It could be suggested that combined modality treatment might be necessary for the treatment of stage I and II Non-Hodgkin's lymphoma of unfavorable histology.

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A Triangulation and Guard Sufficiency Set of the Hierarchy of Simple Polygons (단순 다각형 계층구조에서의 삼각화와 경비가능충분집합)

  • Yang, Tae-Cheon
    • The KIPS Transactions:PartA
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    • v.15A no.5
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    • pp.295-300
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    • 2008
  • In this paper, we consider a characterization of a Guard Sufficiency Set(GSS) in the hierarchy of simple polygons. we propose the diagonals of a arbitrary triangulation of a polygon as a GSS when guards see the diagonals with completely visibility and both sides of the diagonal. we show that this can be a GSS in convex polygons, unimodal polygons, spiral polygons but this can not be a GSS in star-shaped polygons, monotone polygons, completely external visible polygons.