• Journal of Chest Surgery
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• v.31 no.10
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• pp.1004-1008
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• 1998

We report a case of heart-lung transplantation in a 32 year-old female with Eisenmenger syndrome secondary to patent ductus arteriosus. She has been suffered from congestive heart failure since June 1996 and repeatedly treated at Intensive Care Unit with intravenous inotropic support since July 1997. Preoperative echocardiography showed a patent ductus arteriosus with right to left shunt, severe regurgitation of tricuspid valve and estimated right ventricular systolic pressure of 100mmHg. The brain-dead donor was an 18 year-old male with head trauma from traffic accident 3 days ago. Heart-lung block procurement was performed at another general hospital and was transported to the Seoul National University Hospital by ambulance. Total ischemic time of the transplanted heart and lung were 249 minutes and 270 minutes, respectively. The immunosuppressive therapy was commenced preoperatively with cyclosporine and azathioprine. Corticosteroid was not used until postoperative 3 weeks in order to avoid infection and delayed healing at the tracheal anastomotic site. The patient was discharged at 31st postoperative day, and has been regularly followed up at outpatient clinic without specific complication. The follow-up bronchoscopy, performed 2 weeks and 4 months after surgery, revealed no evidence of cellular rejection.

• 한국해양학회지
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• v.20 no.2
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• pp.28-39
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• 1985

The driving mechanisms for low level jets(LLJ) and coastal surface maximum winds are studied with observed wind data from June, 1976 through August, 1980 at Port Aransas and Victoria, Texas, in connection with a baroclinic model. This model is developed considering the forcing functions such as the synoptic and meso-scale pressure gradient, the frictional force, and the atmospheric stability. The results show that a LLJis observed on over 95% of the occasions when a nighttime coastal wind maximum occurred. Baroclinicity generated by sloping terrain during the summertime causes the diurnal variation in the thermal field. This thermal wind component would then decrease the prevailing synoptic-scale southerly wind by day and allow it to increase at night. Nighttime atmospheric stability leads to frictional decoupling which enhances the nocturnal LLJ. At the coastal site neutral stability prevails, thus all owing downward transfer of momentum from the nocturnal LLJ and results in the nocturnal coastal surface wind maximum. The height of LLJis not uniquely related to the inversion layer, and the results of the computations using this model show a good agreement with the observations.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.14 no.3
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• pp.49-58
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• 2000

This paper deals with a systematic approach to neural network controller design for static VAR compensator (SVC) using a learning algorithm of error back propagation that accepts error and change of error as inputs, the momentum learning technique is used for reduction of learning time, to improve system stability. A SVC, one of the Flexible AC Transmission System(FACTS), constructed by a fixed capacitor(FC) and a thyristor controlled reactor(TCR), is designed and implemented to improve the damping of a synchronous generator, as well as controlling the system voltage.TO verify the robustness of the proposed method, we considered the dynamic response of generator rotor angle deviation, angular velocity deviation and generator terminal voltage by applying a power fluctuation and rotor angle fluctuation in initial point when heavy load and normal load. Thus, we prove the usefulness of proposed method to improve the stability of single machine-infinite bus with SVC system.

• Journal of Embryo Transfer
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• v.19 no.2
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• pp.101-112
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• 2004

Chloride($Cl^-$) channels play critical roles in cell homeostasis and its specific functions such as volume regulation, differentiation, secretion, and membrane stabilization. The presence of these channels have been reported in all kinds of cells and even in frog oocytes. These essential role of $Cl^-$­ channels in cell homeostasis possibly play any role in egg homeostasis and in the early stage of development, however, there has been no report about the presence of $Cl^-$­ channel in the mammalian oocyte. This study was performed to elucidate the presence of $Cl^-$­ channels in hamster eggs. When allowing only $Cl^-$­ to pass through the channel of the egg membrane by using impermeant cation such as N-methyl-D-glucamine(NMDG), single channel currents were recorded. These channel currents showed typical long-lasted openings interrupted by rapid flickering. Mean open $time({\tau}o)$ was 43${\pm}$10.14 ms(n=9, at 50 mV). The open probability(Po) was decrease with depolarization. The current-voltage relation showed outward rectification. Outward slop conductance(32${\pm}$5.4 pS, n=22) was steeper than the inward slop conductance(10${\pm}$1.3 pS). Under the condition of symmetrical 140 mM NaCl, single channel currents were reversed at 0 mV(n=4). This reversal potential(Erev) was shifted from 0 mV at 140 mM concentration of internal NaCl(140 mM [Na+]i) to ­9.8${\pm}$0.5 mV(n=4) at 70 mM [Na+]i and 11.5${\pm}$1.9 mV at 280 mM [Na+]i(n=4) respectively, strongly suggesting that these are single $Cl^-$­ channel currents. To examine further whether this channel has pharmacological property of the $Cl^-$­ channel, specific Cl­ channel blockers, IAA-94(Indanyloxyacetic acid-94) and DIDS(4, 4'-diisothiocyan ostillben- 2-2'disulfonic acid) were applied. IAA-94 inhibited the channel current in a dose-dependent manner and revealed a rapid and flickering block. From these electrophysiological and pharmacological resluts, we found the novel $Cl^-$­ channel present in the hamster oocyte membrane. The first identification of $Cl^-$­ channel in the hamster oocyte may give a clue for the further study on the function of $Cl^-$­ channel in the fertilization and cell differentiation.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.1068-1072
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• 2005

조석이란, 해면의 완만한 주기적 승강을 말하며, 보통 그 승강은 1일 약 2회이나, 곳에 따라서는 1일 1회의 곳도 있다. 조석에 있어서는 이 밖에 수일의 주기를 갖는 약간 불규칙한 승강, 반년, 또는 1년을 주기로 하는 다소 규칙적인 승강까지 포함하여 취급한다. 그러나, 각 항만마다 갖는 특정적인 주기인 수분내지 수십분의 주기의 승강은 조석으로 취급하지 않는다. 조석은 해양의 제현상 중에서 예측가능성이 가장 큰 현장으로 이는 조석이 천체의 운행과 연관되기 때문이다. 조석이란 지구로부터 일정한 거리에서 각 고유의 속도를 가지는 적도상을 운행하는 무수의 가상천체에 기인하는 규칙적인 개개의 조석을 합성한 것이며 이 개개의 조석을 분조(Constituent)라 한다. 여기에서 사용되는 신경망 모형은 입력과 출력으로 구성되는 블랙박스 모형으로서 하나의 시스템을 병렬적으로 비선형적으로 구축할 수 있다는 장점 때문에 과거 하천유역의 강우-유출과정에서의 경우 유출현상을 해석하고 유출과정을 모형화 하기 위해 사용하였다. 본 연구에서는 기존의 조위 예측방법인 조화분석법이 아닌 인공신경망을 이용하여 조위예측을 실시하였다. 학습이라는 최적화 과정을 통해 구조와 기능이 복잡한 자연현상을 그대로 받아들여 축적시킴으로써 이를 지식으로 현상에 대한 재현능력이 뛰어나고, 또한 신경회로망의 연상기억능력에 적용하여 수학적으로 표현이 불가능한 불확실한 조위곡선에 적용하기에 유리한 장점을 가지고 있다. 본 연구의 목적은 과거 조위이론을 통해 이루었던 조위예측을 우리가 알기 쉬운 여러 기후인자(해면기압, 풍향, 풍속, 음력 등)에 따른 조위곡선을 예측하기 위해 신경망 모형을 이용하여 여수지역의 조위에 적용하여 비교 분석하고자 한다. May가 제안한 공식을 더 확장하여 적용할 수 있는 실험 공식으로 개선하였으며 다양한 조건에 대한 실험을 수행하여 보다 정밀한 공식으로 개선할 수 있었다.$10,924m^3/s$ 및 $10,075m^3/s$로서 실험 I의 $2,757m^3/s$에 비해 통수능이 많이 개선되었음을 알 수 있다.함을 알 수 있다. 상수관로 설계 기준에서는 관로내 수압을 $1.5\~4.0kg/cm^2$으로 나타내고 있는데 $6kg/cm^2$보다 과수압을 나타내는 경우가 $100\%$로 밸브를 개방하였을 때보다 $60\%,\;80\%$ 개방하였을 때가 더 빈번히 발생하고 있으므로 대상지역의 밸브 개폐는 $100\%$ 개방하는 것이 선계기준에 적합한 것으로 나타났다. 밸브 개폐에 따른 수압 변화를 모의한 결과 밸브 개폐도를 적절히 유지하여 필요수량의 확보 및 누수방지대책에 활용할 수 있을 것으로 판단된다.8R(mm)(r^2=0.84)$로 지수적으로 증가하는 경향을 나타내었다. 유거수량은 토성별로 양토를 1.0으로 기준할 때 사양토가 0.86으로 가장 작았고, 식양토 1.09, 식토 1.15로 평가되어 침투수에 비해 토성별 차이가 크게 나타났다. 이는 토성이 세립질일 수록 유거수의 저항이 작기 때문으로 생각된다. 경사에 따라서는 경사도가 증가할수록 증가하였으며 $10\% 경사일 때를 기준으로 $Ro(mm)=Ro_{10}{\times}0.797{\times}e^{-0.021s(\%)}$로 나타났다.천성 승모판 폐쇄 부전등을 초래하는 심각한 선