• Korean Journal of Biological Psychiatry
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• v.29 no.2
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• pp.33-39
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• 2022

Objectives The early growth response 3 (EGR3) gene located in chromosome 8p21.3 is one of the susceptibility loci in many psychiatric disorders. EGR3 gene plays critical roles in signal transduction in the brain, which is involved in neuronal plasticity, neuronal development, learning, memory, and circadian rhythms. Recent studies have suggested EGR3 as a potential susceptibility gene for bipolar disorder (BPD). However, this requires further replication with an independent sample set. Methods To investigate the genetic role of EGR3 in Korean patients, we genotyped six single-nucleotide polymorphisms (SNPs) in the chromosome region of EGR3 in 1076 Korean BPD patients and 773 healthy control subjects. Results Among the six examined SNPs of EGR3 (rs17088531, rs1996147, rs3750192, rs35201266, rs7009708, rs1008949), SNP rs35201266, rs7009708, rs1008949 showed a significant association with BPD (p = 0.0041 for rs35201266 and BPD2, p = 0.0074 for rs1008949 and BPD, p = 0.0052 for rs1008949 and BPD1), which withstand multiple testing correction. In addition, the 'G-C-C-C' and 'G-C-G-C' haplotypes of EGR3 were overrepresented in the patients with BPD (p = 0.0055, < 0.0001, respectively) and the 'G-T-G-C' haplotype of EGR3 was underrepresented in patients with BPD (p = 0.0040). Conclusions In summary, our study supports the association of EGR3 with BPD in Korean population sample, and EGR3 could be suggested as a compelling susceptibility gene in BPD.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2009.10a
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• pp.379-382
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• 2009

Recently, Since the advent of KTX, the Electric Corrosion by leakage current is on the issue. The corrosion of Underground metal establishment near KTX system causing by its high voltage current become very serious problem. So We must figure for this. For the prevention of corrosion, Many methods is on the discussion. In this paper, We studied the Sacrificial Anode in many methods for its high efficiency.

• Proceedings of the KIPE Conference
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• 2017.11a
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• pp.25-26
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• 2017

본 논문은 양극성 직류배전망 연계를 위한 3-level NPC AC/DC 컨버터 제어 시 PI제어와 연산량 감소 모델예측제어를 혼합한 제어 기법을 제안한다. 이를 통해 기존에 비해 향상된 동특성을 확인할 수 있다. 제안하는 제어 기법을 PSIM 시뮬레이션을 통해 검증하였다.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.30 no.3
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• pp.180-184
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• 2017

In this study, we examine the electrical properties of diketopyrrolopyrrole (DPP) containing polymer semiconductors that have been reported to show high performance with ambipolar characteristics. We prepared three different DPP based polymer semiconductors (PDPPTPT, PDPP3T, and PDPP2T-TT) and fabricated organic thin film transistors (OTFTs) with ambipolar polymer semiconductors as an active layer. All three DPP polymers showed only p-type properties at initial measurements. However, after annealing in vacuum oven for 24 hours, it was found that the DPP based polymers have both p-type and n-type properties. It is speculated that the residual impurities supposedly regarded as a strong electron trap source were eliminated during the vacuum process.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.3
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• pp.225-230
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• 2016

Since the development of anodic aluminum oxide (AAO), extensive studies have been conducted ranging from fundamental research to the applications of AAO. Most of the research on AAO structures have focused on well-aligned nanoporous structures fabricated under specific conditions. This study investigated fabricable AAO structures with anodization performed with various temperatures, electrical potentials, and basal plane surfaces. As a result, nanoporous and nanofibrous structures were fabricated. The nanopores were formed at a relatively lower temperature and potential, and the nanofibers were formed at a relatively higher temperature and potential regardless of the basal plane surface. The shape of the base surface was found to influence the structural arrangement in nanoporous morphologies. These interesting findings relating to new morphologies have the potential to broaden the possible applications of AAO materials.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.281-281
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• 2013

본 연구에서는 고출력 금속 인쇄회로기판(Metal PCB) 개발을 위해 절연층으로 양극산화막을 형성하고 이 절연층 위에 Screen Printing 법을 이용하여 Ag paste를 패턴 인쇄한 알루미늄 기판을 사용하였다. 이 기판 위에 무전해 방식으로 구리 박막을 성장시켜, 무전해 도금 조건이 구리 박막 성장에 미치는 영향에 대해 연구하였다. 무전해 도금 시, pH 농도와 plating 온도를 변화시켜 이 변화에 따른 무전해 구리도금 박막의 물리적/전기적 특성을 비교 분석하여 무전해 도금에 의해 형성된 구리 박막과 기판과의 상관 관계도 비교 검토하였다. XRD (X-ray Diffraction), 광학현미경, FE-SEM (Field Emission Scanning Electron Microscope)등을 이용하여 성장된 구리 박막 및 기판의 결정성, 표면 및 단면 형상 등을 측정하였고, XPS (X-ray Photoelectron Spectroscopy)를 이용하여 무전해 도금에 의한 Cu의 화학구조 및 불순물 상태를 조사하였다.

• Korean Journal of Biological Psychiatry
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• v.14 no.1
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• pp.68-71
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• 2007

Quetiapine is an atypical antipsychotic drug with a benign side effect profile. However, recent studies have reported that thyroid dysfunction is associated with quetiapine treatment. The authors report a patient with DSM-IV bipolar I disorder who developed subclinical hypothyroidism during quetiapine treatment. The patient showed no significant clinical symptoms, but only abnormal thyroid function test findings including antithyroglobulin antibody. The abnormal thyroid function test findings were normalized after discontinuation of quetiapine. The subclinical hypothyroidism developed during quetiapine treatment may be associated with autoimmune process.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.2 s.245
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• pp.179-186
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• 2006

Dielectrophoresis has received considerable attention for separating nanotubes according to electronic types. Here we examine the effects of surface conductivity of semiconducting single-walled carbon nanotubes (SWNT), induced by ionic surfactants, on the sign of dielectrophoretic force. The crossover frequency of semiconducting SWNT increases rapidly as the conductivity ratio between the particle and medium increases, leading to an incomplete separation of ionic surfactant suspended SWNT at an electric field frequency of 10 MHz. The surface charge of SWNT is neutralized by an equimolar mixture of anionic surfactant sodium dodecyl sulfate (SDS) and cationic surfactant cetyltrimenthylammonium bromide (CTAB), resulting in negative dielectrophoresis of semiconducting species at 10 MHz. A comparative Raman spectroscopy study shows a nearly complete separation of metallic SWNT.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.249-249
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• 2014

대면적 사각형 기판의 플라즈마 표면처리를 위한 유도 결합 플라즈마 발생 시스템의 수치 계산을 유체 모델을 이용하여 진행하였다. 연산 자원이 많이 요구되는 3차원 모델임을 감안하여 준중성 조건을 이용한 간략화 알고리즘을 사용하였다. Poisson 방정식을 풀지 않고 준중성 조건에 의한 양극성 전기장을 계산하여 이용한다. 쉬스는 모델을 이용하여 처리하였다. 1차적으로 사각 spiral 형태의 안테나를 가정하여 LCD 3세대 급의 기판을 대상으로 작성하였다. 다중 분할을 하지 않고 4개의 가지를 갖는 single spiral을 적용하였고 1.125 turn의 low impedance 구조에 대해서 계산하였다. Ar을 이용한 sputter etching 공정을 타겟으로 하여 기판에서의 Ar 이온 밀도 분포의 균일도가 어떤 설계 변수에 의해서 영향을 받는지를 중점적으로 계산하였다.

• Proceedings of the KIPE Conference
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• 2006.06a
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• pp.400-402
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• 2006

단일 서스테인 구동회로로서 캐패시터를 이용하여 가스 방전 스위치의 전압 스트레스를 절반으로 줄일 수 있는 새로운 멀티레벨 단일 서스테인 구동회로를 제안한다. 기존의 단일 서스테인 구동회로는 +Vs 및 -Vs의 양극성 전원을 사용함에 따라 스위치 전압 스트레스가 2Vs가 되어 스위치로서 전력밀도가 높으면서 가격이 낮은 IGBT를 사용해야 하지만 도통손실이 매우 커 발열에 문제점을 보인다. 제안하는 멀티레벨 단일 에너지 회수 서스테인 구동회로는 에너지 회수 인덕터에 의해 전압이 Vs로 유지되는 부유 캐패시터를 이용하여 가스 방전 스위치의 내압을 기존의 2Vs에서 Vs로 낮추게 되어 스위치 선택의 폭을 넓힐 뿐만 아니라 구동회로의 도통 손실을 개선하여 발열을 줄일 수 있다.