• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.6
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• pp.652-658
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• 2019

When IoT is applied to various research experiment fields such as physics, pharmacy, biology and medicine, it can increase the safety and convenience of researchers by intelligently monitoring and controlling research equipment and environment with various sensors and devices. For accurate and convenient record management and the research history and the basis but also for the reverse tracking, real-time reagent measurement and registration should be provided as a research support automation services. Currently, existing methods of reagent management are operated by computerized method, but reagent registration and management are not automated. And also record is managed manually, there are many hassles and problems such as a record error and too much time required for quantification and registration for many reagents. In this paper, we study a real time reagent measuring and registration method based on IoT to resolve the problems aforementioned, by the information of the reagent acquired by image recognition and NFC method.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.1
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• pp.81-88
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• 2019

Purpose : The purpose of this study was to examine if there is any correlation between pelvic tilt angle and trunk motion and trunk extensor during trunk forward flexion and to measure trunk motion, onset time of trunk motion, and onset time of trunk extensor activation. Methods : The subjects of this study were 42 healthy adults. The subjects had no back pain due to neurological disease and no experience of back surgery. After pelvic tilt angle was measured, each trunk forward flexion was performed three times. Trunk motion and onset time of trunk motion were measured using Myomotion. Four sensors were used, with one located at the upper thoracic (below $C_7$), the lower thoracic ($T_{12}-L_1$), the sacrum ($S_1$), and at the center of the anterior femur. Onset time of trunk extensors (spinalis, longissimus, gluteus medius, gluteus maximus, biceps femoris, and gastrocnemius) activation was measured using a wireless surface EMG. The EMG amplitude was normalized by using the reference voluntary contraction (RVC). The statistical significance of the results were evaluated using Pearson's correlation test. Results : The correlation between pelvic tilt angle and lumbar motion, onset time of pelvis motion, and onset time of gluteus medius activation was statistically significant in a positive direction (p<.05). The correlation between pelvic tilt angle with pelvis motion, onset time of lumbar motion, and onset time of longissimus activation showed a statistically significant negative correlation (p<.05). Conclusion : The study results provide a significant contribution to our understanding of the lumbar load at the initial stage of trunk flexion. Therefore, it may be possible to provide basic data for evaluation and treatment, such as orthodontic treatment for alignment of the spine and back pain. In addition, it is necessary to focus on normal exercise pattern reeducation as well as pelvic correction during exercise in daily life or in industrial fields.

• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.51-56
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• 2019

This study was performed to determine correlation on oral health behavior and variables of planned behavior theory before and after oral health education. 62 male inpatient alcoholics conducted the structured self-administered questionnaires, and subjects were taken oral health education for 4 weeks. To analysis data, the correlation analysis was conducted. The education group showed a significant positive correlation with oral health behavior and behavior intention, attitude toward behavior, subjective norm, perceive behavior control after oral health education. The relevant variables after the oral health education displayed a higher correlation coefficient and relation in the education group. It suggested an evidence that regular oral health education should be applied to promote oral health for alcoholic inpatients.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.3
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• pp.277-285
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• 2019

In this study, effective cosmetic raw material weighing and bulk manufacturing management system were constructed by using bar code or quick response code (QR code) and database. Raw material labels and weighing labels for bulk manufacturing were published in web environment using the information entered in the database using ScriptX, a print component of Medi&Co. By checking the weighing and manufacturing process by using scanner, tablet and PC, it was possible to remarkably improve the product error caused by erroneous amount or misapplication which is the most cause of error in the production of cosmetic bulk. In conclusion, applying a database that utilizes bar code and QR code to cosmetics manufacturing can reduce the various problems in the process, thereby improving quality control and productivity of cosmetics.

• Korean Journal of Pharmacognosy
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• v.50 no.3
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• pp.205-218
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• 2019

This study was conducted to investigate the toxicity symptoms and approximate lethal dose (ALD) of Oplopanax elatus (Nakai) Nakai hydrothermal extract powder by single oral dose toxicity and 4 weeks of repeated oral dose determination. The Sprague-Dawley (SD) male and female rats were treated with 1,250 (low- dosage group), 2,500 (medium- dosage group) and 5,000 (high- dosage group) mg/kg. In the single oral dose toxicity test, no dead animals and toxic symptoms were observed during the experiment. And there were no related with anomalies in normal weight changes and autopsy results. In the four-week repeated oral dose determination test, no death animals and toxicity symptoms were observed during the experiment, and there were no abnormal results in weight changes, feed and negative intake measurements. Results of eye examination, urinalysis, hematological values and serum biochemical values, gross findings and absolute organ were not of singularity. These result demonstrated that no toxic symptoms were observed by the test substance Oplopanax elatus (Nakai) Nakai hydrothermal extract powder under this test condition, and the non-toxic content is determined to be 5,000 mg/kg/day.

• Journal of Sasang Constitutional Medicine
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• v.31 no.3
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• pp.34-47
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• 2019

Introduction Cloninger's Novelty-Seeking (NS) and Harm-Avoidance (HA) were found to be the biopsychological characteristic of Sasang typology, and the So-Yang type has high NS and low HA however the So-Eum type as contrary. The purpose of this study was to show the clinical usefulness of these measures as objective clinical index of Sasang typology in foreign countries lacking validated measures. Methods The Sasang type of 103 university students was diagnosed using Questionnaire for Sasang Constitution Classification (QSCC) II and clinical specialist, and biopsychological and physical features with NS, HA, Sasang Personality Questionnaire (SPQ) and BMI. These measures were normalized to make a noble index of 'NS(100-HA)', and the correlation among these were examined with Pearson's correlation. The differences of biopsychological and physical features between Sasang type groups were attested with ANCOVA, and the comparison of clinical usefulness of SPQ and NS(100-HA) were examined with discriminant analysis. Results SPQ and BMI were clinically useful for Sasang typology as shown in previous studies, and the substitution of SPQ with normalized NS(100-HA) was found acceptable. The NS(100-HA) is significantly correlated with SPQ (r=0.466, p<0.01), however not with BMI (r=0.079, ns). The SPQ and NS(100-HA) scores were found to be distinctive between Sasang type groups, and these were found to predict Sasang type of participants with similar correctness. Discussion and Conclusion The current study reviewed the theoretical backgrounds and confirmed the clinical usefulness of Cloninger's biopsychological theory in Sasang typology. These might provide foundations for integrative medicine and cross-cultural biopsychology of the East and West.

• The Journal of the Convergence on Culture Technology
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• v.5 no.2
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• pp.389-395
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• 2019

This study investigated the pharmaceutical extraction and the functional health food extraction, which have a beneficial effect on the human body and which can be used safely for a long period of time without adverse side effects and also have excellent effects of protecting liver and improving liver function. As the results, the cabbage extract does not show cytotoxicity, and thus can be used safely. In an experiment performed on an animal model with liver injury induced by a drug (APAP), it could be seen that the cabbage extract exhibited the effects of protecting liver and improving liver function by effectively reducing AST and ALT which are liver injury markers, indicating that the cabbage extract is effective as a pharmaceutical extraction for preventing or treating liver disease. In particular, the cabbage extract was effective in treating inflammation of the liver by reducing the expression of the inflammatory mediators iNOS and COX-2 and the proinflammatory cytokine $IL-1{\beta}$, which are involved in acute inflammatory reactions accompanying liver injury. In the results, an extract of cabbage heat-treated at a temperature of 100 to $150^{\circ}C$ had a better liver function-improving effect or anti-inflammatory effect than an extract of raw cabbage.

• The Journal of the Convergence on Culture Technology
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• v.5 no.2
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• pp.397-404
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• 2019

This study was carried out to investigate the heat-treated broccoli extraction which have a beneficial effect on the human body and which can be used safely for a long period of time without adverse side effects and also have excellent effects of protecting liver and improving liver function. The heat-treated broccoli extract does not show cytotoxicity, and thus can be used safely. In an experiment performed on an animal model with liver injury induced by a drug (APAP), it could be seen that the heat-treated cabbage extract exhibited the effects of protecting liver and improving liver function by effectively reducing AST and ALT which are liver injury markers, indicating that the heat-treated brocoli extract is effective as a pharmaceutical extraction for preventing or treating liver disease. In particular, the heat-treated broccoli extract was effective in treating inflammation of the liver by reducing the expression of the inflammatory mediators iNOS and COX-2 and the proinflammatory cytokine $IL-1{\beta}$, which are involved in acute inflammatory reactions accompanying liver injury.

• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.91-97
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• 2019

The aim of this study was to compare effects of oral health education on oral health behavior according to demographic and dental health-related characteristics in inpatient alcoholics. 62 alcoholic male patients were recruited to 32 patients at education group and 30 at non-education group. To search demographic and dental health-related characteristics, the self-administered structured questionnaires were used, and the survey was conducted before and after the oral health education. The oral health education program was consisted of 40 mins theoretical education and individual tooth brushing training once a week for 4 weeks. The oral health education for alcoholic patients had big effects on oral health behavior. And these results indicate that if oral health program was performed systematically in alcohol counseling centers or alcohol hospitals, more oral health promotion effects will appear.

• Journal of the Korea Convergence Society
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• v.12 no.3
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• pp.53-59
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• 2021

When using Medical Information Retrieval services, a typical retrieval method is to use the Anatomic Therapyutic Chemical Classification (ATC) code. Traditional ATC code-based medical information retrieval is very useful for single ingredient product retrieval with single ingredient. However, in the case of complex, retrieval errors often occur. The cause of this problem is that ATC code-based retrieval proceeds by pattern matching ATC code.In this work, we design the mapping scheme based on ATC code by analyzing the requirement scenarios for retrieval based on main ingredient in ATC code-based retrieval. the mapping scheme based on ATC is a schema that stores the ATC code of the complex and all the ATC code of the single agent included in the complex. ATC code-based retrieval using this schema retrieves a complex as ingredient of a single ingredient product, thus having higher accuracy than existing methods. the mapping scheme based on ATC is expected to increase the efficiency of doctors' prescription of patients and increase the accuracy of drug safety use services.