• Title/Summary/Keyword: 약학

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Inhibition of C2-ceramide induced contraction in cat esophageal smooth muscle cell by newly synthesized Ceramide analogues

  • Lee, Doo-Won;Yang, Sung-Jun;Lee, Yul-Pyo;Lee, Tai-Sang;Park, Jun-Hong;Choi, Su-Hang;Yim, Chul-Bu;Sohn, Uy-Dong;Choi, Tae-Sik
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.248.1-248.1
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    • 2002

  • It has been shown that C2-ceramide (C2), short chain ceramide, plays a role in mediating contraction of cat esophageal smooth muscle cells. We examined the effect of newly synthesized ceramide analogues on the C2-ceramide induced contraction in esophageal smooth muscle cells isolated with collagenase. C2-ceramide produced contraction of smooth muscle cells in a dose dependent manner. (omitted)

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