Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.248.1-248.1
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- 2002
Inhibition of C2-ceramide induced contraction in cat esophageal smooth muscle cell by newly synthesized Ceramide analogues
- Lee, Doo-Won (College of Pharmacy, Chung Ang University) ;
- Yang, Sung-Jun (College of Pharmacy, Chung Ang University) ;
- Lee, Yul-Pyo (College of Pharmacy, Chung Ang University) ;
- Lee, Tai-Sang (College of Pharmacy, Chung Ang University) ;
- Park, Jun-Hong (College of Pharmacy, Chung Ang University) ;
- Choi, Su-Hang (College of Pharmacy, Chung Ang University) ;
- Yim, Chul-Bu (College of Pharmacy, Chung Ang University) ;
-
Sohn, Uy-Dong
(College of Pharmacy, Chung Ang University)
;
- Choi, Tae-Sik (College of Pharmacy, Chung Ang University)
- Published : 2002.10.01
Abstract
It has been shown that C2-ceramide (C2), short chain ceramide, plays a role in mediating contraction of cat esophageal smooth muscle cells. We examined the effect of newly synthesized ceramide analogues on the C2-ceramide induced contraction in esophageal smooth muscle cells isolated with collagenase. C2-ceramide produced contraction of smooth muscle cells in a dose dependent manner. (omitted)
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