• Title/Summary/Keyword: 액체약

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Preparation and Characteristics of Poly(ε-caprolactone) Microcapsules Containing Pseudomonas by W/O/W Emulsion (다중에멀젼법을 통한 슈도모나스를 함유하는 PCL 마이크로캡슐의 제조 및 특성 연구)

  • Kim, Ki-Seok;Lee, Seung-Yeop;Lee, Gun-Woong;Kim, Hyung-Gon;Park, Soo-Jin
    • Polymer(Korea)
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    • v.36 no.2
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    • pp.202-207
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    • 2012
  • Biodegradable poly(${\varepsilon}$-caprolactone)(PCL) microcapsules containing pseudomonas were prepared by W/O/W emulsion system. The characteristics and release behaviors of the microcapsules were investigated as a function of manufacturing conditions. The morphology and particle distribution of the microcapsules were observed by a scanning electron microscope and a particle size analyzer. The release behaviors of the pseudomonas were determined using a cell culture method. It was found that smooth and spherical microcapsules were formed by W/O/W emulsion system and particle size was in the range of 10 to 60 ${\mu}m$. The release behaviors of the pseudomonas were influenced by the manufacturing conditions. It was indicated that the increase of the surfactant content and stirring rate led to an increased release rate, resulting from the high specific surface area of the smaller particle size, and the increase of the PCL content provided the sustained release behaviors by the delay effect of diffusion in the release medium.

A Case of the Dentigerous Cyst which produce the Facial and Palatal Deformity (안면부 및 경구개부 기형을 초래한 거대 여포성 치아낭종 1례)

  • 박순일;문태용;이석용;윤강묵;심상열
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.12.1-12
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    • 1981
  • The dentigerous cyst originates through alteration of the reduced enamel epithelium after the crown of the tooth has been completely formed, with accumulation of fluid between the reduced enamel epithelium and the tooth crown. The dentigerous or follicular cyst comprises about 20% of all dental cysts. It usually occurs between 20 and 30 years of age but is occasionally seen in children or in old people. The most common sites of this cyst are the mandibular third molar and maxillary cuspid areas, since these are the most commonly impacted teeth. Many of these cysts give no clinical symptoms until noticeable asymmetry of the face develops. Rarely it develops to an ameloblastoma, epidermoid carcinoma and mucoepidermoid carcinoma, so early removal leads to better result. Roentgenographic examination of the jaw involved by a dentigerous cyst will reveal a radiolucent area. Recently the authors have experienced a giant dentigerous cyst which produced the bony deformity of the maxillary and hard palate bone. The cyst was completely removed under the local anesthesia by Caldwell-Luc approach.

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Effect of Growth Conditions in the Attachment of Salmonella typhimurium to the Host Cells (생육조건에 따른 Salmonella typhimurium의 숙주세포 부착성)

  • Kim, Young-Hee;Kim, Sam-Woong;Kang, Ho-Young
    • Journal of Life Science
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    • v.15 no.4 s.71
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    • pp.641-646
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    • 2005
  • An approximately 10-fold higher level of adherence of Salmonella typhimurium strain TML to Int-407 cells was observed with organisms grown in Luria broth or in high-iron containing medium than those grown in low-iron containing medium. Iron specifically enhanced adherence, while other cations such as calcium, cobalt, copper, potassium, magnesium and manganese did not. It was suggested that iron did not act as a passive ligand - probably it stimulated production of bacterial factors necessary for adherence. A similar pattern of iron modulation of adhesiveness was also seen in Salmonella mutants with single or different combinations of multiple mutations in genes encoding the mannose sensitive hemagglutinin (type 1 fimbriae), mannose resistant hemagglutinin and flagellum. The adhesiveness of an isogenic fur mutant was modulated by iron in a manner similar to the wild-type strain, suggesting that iron modulation of adherence is independent of the fur gene product.

Measurement and Prediction of Autoignition Temperature(AIT) of n-Decane+Ethylbenzene System (노말데칸과 에틸벤젠 계의 최소자연발화온도 측정 및 예측)

  • Lee, Jae-Hwa;Kim, Gui-Ju;Hong, Soon-Kang;Ha, Dong-Myeong
    • Journal of the Korean Institute of Gas
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    • v.19 no.5
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    • pp.54-60
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    • 2015
  • The autoignition temperature (AIT) of a material is the lowest temperature at which the material will spontaneously ignite. The AIT is important index for the safe handling of flammable liquids which constitute the solvent mixtures. This study measured the AITs of n-decane+ethylbenzene system by using ASTM E659 apparatus. The AITs of n-decane and ethylbenzene which constituted binary system were $210^{\circ}C$ and $430^{\circ}C$, respectively. The experimental AITs of n-decane+ethylbenzene mixture were a good agreement with the calculated AITs by the proposed equations with about $11^{\circ}C$ A.A.D.(average absolute deviation).

Characteristics of Extracellular $\beta$-Glucosidase in Tricholoma matsutake (송이의 세포외 분비 $\beta$-Glucosidase 효소의 특성)

  • 민응기;한영환
    • KSBB Journal
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    • v.15 no.1
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    • pp.9-13
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    • 2000
  • In order to determine the characteristics of $\beta$-glucosidase associated with cellulose degradation, the enzyme produced extracellularly by the mycelia of Tricholoma matsutake DGUM 26001 in culture broth was partially purified. The enzyme activity was maintained in the range of temperatures trom 55 to $70^{\circ}C$ and its optimum temperature was $65^{\circ}C$. The $\beta$-glucosidase enzyme showed relatively high activity in the range of pH 3.0-5.0 and its optimum pH was 4.0. Under the optimal conditions, the specific activity of $\beta$-glucosidase for salicin as a substrate was 18.7 unit/mg protein. After thermal treatment of the enzyme at $55^{\circ}C$ for 60 min, more than 90% of the enzyme activity was still sustained. Iron($Fe^{++}$) stimulated enzyme activity, whereas mercury($Hg^{++}$) and copper($Cu^{++}$) inhibited. Compared to salicin as a substrate, the relative activity for cellobiose was observed to be 48.6%. The apparent $K_m$ and $V_{max}$ of the enzyme with cellobiose were 0.12 mM and 0.02 umol/min, respectively.

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Studies on the Utilization of Waste Ginseng Meal -Effect of Waste Ginseng Meal on Alcohol Fermentation and Yeast Reproduction- (인삼박의 이용에 관한 연구 -인삼박 당화액이 효모의 증식 및 알콜발효에 미치는 영향-)

  • 주현규;권우건
    • Microbiology and Biotechnology Letters
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    • v.7 no.4
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    • pp.191-195
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    • 1979
  • This study was conducted to investigate the effect of saccharified extract of ginseng meal on alcohol fermentation and reproduction of yeast. Different concentrations of saccharified extract of ginseng meal in liquid medium were tested, and the experimental results obtained were summarized as follows : 1. In the process of alcohol fermentation of yeast, $CO_2$ output was much accelerated by the higher concentration of saccharied extracts from 1% to 6%, but $CO_2$ output was disurbed at the concentrations of 10% and 15%. .2. In the process of alcohol fermentation of yeast, the production of alcohol was increased by the higher concentration of saccharified extracts from 1% to 6%, but decreased at the concentrations of 10% and 15%. 3. Number of reproduced yeast cell after aerobic culture of Sacc. cervisiae was increased by the higher concentration of saccharified extracts from 1% to 10%, but decreased at the concentration of 15%. The number of yeast cell at the concentratin of 10% extract was 1.6 times more than that of control.

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Cleaning and Decontamination Method of Books for Their Sanitary Circulation (책의 위생적 유통관리를 위한 세정 소독 방법)

  • Kim, Nam Yong;An, Duck Soon;Choi, Young Il;Jung, Yong Bae;Kim, Jung Min;Lee, Dong Sun
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.19 no.1
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    • pp.11-15
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    • 2013
  • In order to find a sanitary logistic way to handle library books, papers and environmental sources contacting the books were tested in their microbial contamination load and methods to decontaminate the books were investigated. Generally bacterial load of inner book pages was very low, but increased when contaminated with liquid such as saliva. In contrast, their lateral ends showed much higher bacterial contamination presumably due to dry dust contamination on there. As operations to improve the sanitary book conditions, turbulent air blow was found to be workable for reducing dry dusty contamination and 280 nm ultra-violet (UV) light emitting diode (LED) was so for decontaminating wet surface contamination. Microbial inactivation by the UV LED could be realized with irradiation for more than 5 minutes at 2 cm distance. Air blow of 5.5 m/s for 0.5~1 minute could reduce the dusty contamination on a model book surface.

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Endothermic Properties of Liquid Fuel Decomposition Catalyst Using Metal Foam Support (메탈폼 지지체를 이용한 액체연료 분해반응 촉매의 흡열특성)

  • Mun, Jeongin;Kim, Nari;Jeong, Byunghun;Jung, Jihoon
    • Korean Chemical Engineering Research
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    • v.59 no.4
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    • pp.481-486
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    • 2021
  • In a hypersonic vehicle to solve the heat problem generated during flight, a cooling technology is being developed which uses the endothermic effect that appears during the decomposition reaction of the mounted fuel. In this study, the decomposition reaction of n-dodecane fuel was performed using HZSM-5 as a catalyst, and the catalyst was coated on metal foam to maximize the endothermic effect of the catalytic decomposition reaction and suppress coke formation. The reactor was a stainless steel flow reactor with a outer diameter of 1.27 cm, and the reaction temperature was 550 ℃, the reaction pressure was 4 MPa, and the flow rate was 12 ml per minute. As a result of the catalytic decomposition reaction using a catalyst coated with HZSM-5 on the metal foam, the heat sink was 2887 kJ/kg as a maximum, the gas phase conversion rate was 34%, and the amount of coke produced on the metal foam decreased by about 56% as the catalyst was coated compared to the uncoated catalyst.

Establishment and Verification of One-Dimensional Thermal Analysis Technique for Design of Combustion Chamber Cooling Channel (연소실 냉각채널 설계를 위한 1차원 열 해석 기법 확립 및 검증)

  • Kim, Wanchan;Yu, Isang;Shin, Donghae;Ko, Youngsung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.47 no.2
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    • pp.122-129
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    • 2019
  • Predicting heat transfer from the inner wall of the combustion chamber of the liquid rocket is a very difficult task. Several complex processes, such as convection, radiation and conduction must be taken into consideration. Usually commercial programs are used for the analysis of this processes. However, commercial programs are not a perfect solution, because of the long calculation times and a burdening data-input work. In this study, we developed and implemented one - dimensional thermal analysis. This technique can be easily used on the initial stage. The design of the combustion chamber's cooling channel of the steam generator designed using developed technique. In order to compare experimental and theoretical data, the combustion test was performed. Obtained experimental data for the coolant temperature differ from the theoretical prediction by only 8.5%.

Synthesis of Starch-g-PAN Polymer Electrolyte Membrane and Its Application to Flexible Solid Supercapacitors (Starch-g-PAN 고분자 전해질막 합성 및 플렉서블 고체 슈퍼 캐퍼시터 응용)

  • Min, Hyo Jun;Jung, Joo Hwan;Kang, Miso;Kim, Jong Hak
    • Membrane Journal
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    • v.29 no.3
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    • pp.164-172
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    • 2019
  • In this work, we demonstrate a facile process to prepare an electrolyte membrane for the supercapacitor based on a graft copolymer consisting of starch and poly(acrylonitrile) (PAN). The graft copolymer (starch-g-PAN) was synthesized via free radical polymerization initiated by ceric ions. The starch-g-PAN was dissolved in ionic liquid, i.e. 1-ethyl-3-methylimidazolium dicyanamide (EMIM DCA) without any organic solvents at room temperature. The gelation of polymer electrolyte membranes occurred by applying high temperature, i.e. $100^{\circ}C$ for 1 hour. The resultant electrolyte membrane was flexible and thus applied to flexible solid supercapacitors. The performance of the supercapacitor based on starch-g-PAN graft copolymer electrolyte reached 21 F/g at a current density of 0.5 A/g. The cell also showed high cyclic stability with 86% of retention rate within 10,000 cycles. The preparation of starch-g-PAN based polymer electrolyte membrane provides opportunities for facile fabrication of flexible solid supercapacitors with good performance.