• 제목/요약/키워드: 압궤실험

검색결과 15건 처리시간 0.03초

궁둥신경 손상을 유발한 흰쥐에서 운동이 근육재생에 미치는 영향 (Effect of Exercise on Muscle Recovery of Sciatic Nerve Injured Rats)

  • 노효련
    • 한국산학기술학회:학술대회논문집
    • /
    • 한국산학기술학회 2010년도 춘계학술발표논문집 2부
    • /
    • pp.855-858
    • /
    • 2010
  • 이 연구의 목적은 흰쥐의 궁둥신경의 손상을 준 뒤 달리기운동을 시켜 운동이 근육재생에 효과가 있는지를 밝힐 목적으로 시행하였다. 수컷 Sprague-Dawley계 흰쥐의 궁둥신경을 압궤손상을 준후, 하루 60분 씩 주 5회 운동을 시켰다. 궁둥신경 압궤손상 후 12일(5일간 운동), 19일(10일간 운동), 26일(15일간 운동), 33일(20일간 운동 및 61일(40일간 운동)에 흰쥐를 희생시켜 장딴지근육을 절취하여 냉동절편을 만들었으며 중간세사인 desmin과 vimentin에 대한 면역조직화학적 염색방법을 시행하였고 NADH-TR을 이용한 효소조직화학적 방법으로 뼈대근육의 변성 등을 관찰하였다. 중간세사단백 중 desmin은 근육섬유의 변성 및 재생과정 모두에서 발현되며 vimentin은 재생과정에서만 발현되었다. 대조군보다 실험군에서 desmin과 vimentin의 면역 반응성이 높았고, 실험군의 근육섬유들은 손상 후 61일째에 횡단면에서 각을 갖고 있어 정상 근육섬유임을 입증해 주었으나 대조군의 근육섬유는 정상으로 회복되지 않은 둥근 근육섬유가 관찰되었다. 19일째의 NADH-TR반응에서 대조군에서는 근육 섬유형 군집(fiber type grouping)으로 인해 diformazan 과립이 뭉쳐져 있음을 볼 수 있으나 실험군에서는 점점 diformazan 과립이 고르게 분포됨을 볼 수 있었다. 재신경지배가 일어 날 때 나타나는 표적근육섬유(target fiber)는 NADH-TR반응에서 26일 실험군의 일부 근육섬유에서 처음으로 관찰되었다. 61일째 NADH-TR반응에서 대조군은 아직도 diformazan 과립이 근육섬유성 군집을 보였으나 실험군에서는 정상군과 다름없는 염색성이 관찰되었다. 이상의 결과로 흰쥐 궁둥신경 압궤손상 후 트레드밀 달리기 운동이 흰쥐 다리 뼈대근육의 중간세사발현에 효과가 있다고 생각된다.

  • PDF

차체구조용 박육단면부재의 단면형상변화에 따른 축압궤 특성에 관한 연구 (A Study on the Axial Collapse Characteristics of Thin-Walled Members for Vehicles on the Variation of Section Shapes)

  • 이길성;백경윤;차천석;정진오;양인영
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 2003년도 춘계학술대회 논문집
    • /
    • pp.1549-1552
    • /
    • 2003
  • The front-end side members of automobiles absorb most of the energy in a front-end collision. The front-end side members are required to have a high stiffness together with easiness to collapse sequentially to absorb more impact energy. The axial static collapse test (5mm/mim) was conducted by using UTM with respect to the single hat shaped section members which are the standard section shape of the spot welded section members, to the single cap shaped section members, to the double cap shaped section members and to the double hat shaped section members whose section shape are changed in order to give more stiffness. As a result of test, the energy absorbing characteristic was analyzed for different section shapes. That is, it was analyzed that the change of section shape influenced the absorbing energy, the mean collapse load and the maximum collapse load, and that the relation between the change of section shape and the collapse mode.

  • PDF

모자형 단면 점용접부재의 축방향 압궤특성에 관한 연구(II) (A Study on the Collapse Characteristics of Hat-shaped Members with Spot Welding under Axial Compression(II))

  • 차천석;양인영
    • 한국정밀공학회지
    • /
    • 제17권5호
    • /
    • pp.195-201
    • /
    • 2000
  • The fundamental spot welded sections of automobiles (hat-shaped and double hat-shaped sections) absorb most of the energy in a front impact collision. The sections of various thickness, shape and weld width on the flange lave been tested on axial impact crush load (Mass 40kg, Velocity 7.19m/sec) using a vertical air pressure crash est device Characteristics of impact collapse have been reviewed and a structure of optimal energy absorbing capacity is suggested.

  • PDF

차체구조용 박육부재의 단면형상변화에 따른 에너지흡수 특성 (Energy Absorbing Characteristics of Thin-Walled Members for Vehicles Having Various Section Shapes)

  • 차천석;정진오;이길성;백경윤;양인영
    • 한국정밀공학회지
    • /
    • 제20권10호
    • /
    • pp.177-182
    • /
    • 2003
  • The front-end side members of automobiles absorb most of the energy in a case of front-end collision. The front-end side members are required to have a high stiffness together with easiness to collapse sequentially to absorb more impact energy. The axial static collapse test (5mm/min) was conducted by using UTM for form different types of members which have different cross section shapes; single hat, single cap, double cap, and double hat. The single hat shaped section member has the typical standard section, which the double hat shape section has a symmetry in the center to have more stiffness. As a result of the test, the energy absorbing characteristic was analyzed for different section shapes. It turned out that the change of section shape influence the absorbing energy, the mean collapse load and the maximum collapse load, and the relation between the change of section shape and the collapse mode.

차체구조용 CFRP 사이드부재의 정적 압궤특성에 관한 연구 (A Study on the Static Collapse Characteristics of CFRP Side Member for Vehicle)

  • 이길성;양인영
    • 한국복합재료학회:학술대회논문집
    • /
    • 한국복합재료학회 2005년도 추계학술발표대회 논문집
    • /
    • pp.83-86
    • /
    • 2005
  • The front-end side members of automobiles, such as the hat-shaped section member, absorb most of the energy during the front-end collision. The side members absorb more energy in collision if they have higher strength and stiffness, and stable folding capacity (local buckling). Using the above characteristics on energy absorption, vehicle should be designed light-weight to improve fuel combustion ratio and reduce exhaust gas. Because of their specific strength and stiffness, CFRP are currently being considered for many structural (aerospace vehicle, automobiles, trains and ships) applications due to their potential for reducing structural weight. Although CFRP members exhibit collapse modes that are significantly different from the collapse modes of metallic materials, numerous studies have shown that CFRP members can be efficient energy absorbing materials. In this study, the CFRP side members were manufactured using a uni-directional prepreg sheet of carbon/Epoxy and axial static collapse tests were performed for the members. The collapse mode and the energy absorption capability of the members were analyzed under the static load.

  • PDF

최적 충격특성에 갖는 차체구조용 점용접 박육단면부재의 개발 -충격속도변화에 따른 압궤특성을 중심으로- (Development of Vehicle Members with Spot Welded Thin-wall Section for Optimum Impart Characteristic -Based on Collapse Characteristics on the Varied Impact Velocities-)

  • 양인영;차천석;강종엽
    • 대한기계학회논문집A
    • /
    • 제25권7호
    • /
    • pp.1131-1138
    • /
    • 2001
  • This paper concerns the crashworthiness of the widely used vehicle structure, the spot welded hat and double hat shaped section members, which are excellent on the point of the energy absorbing capacity and low production cost. The target of this paper is to analyze the energy absorption capacity of the structure against the front-end collision, and to obtain useful information for designing stage. Changing the spot weld pitches on the flanges, the hat and double hat shaped section members were tested on the axial collapse loads in impact velocities of 4.72m/sec, 6.54m/sec, 7.19m/sec and 7.27m/sec. To efficiently review the collapse characteristics of these sections, the simulation have been carried out using explicit FEM package, LS-DYNA3D. The solutions are compared with results from the impact collapse experiments.

FEM에 의한 단일모자형 단면부재의 축방향 충격압궤 해석 (Axial Impact Collapse Analysis on Hat-shaped Members by FEM)

  • 차천석;강종엽;양인영
    • 한국정밀공학회지
    • /
    • 제17권12호
    • /
    • pp.129-136
    • /
    • 2000
  • In the frontal collision the spot welded hat-shaped section side member is the fundamental structure for automobiles and has a great amount of absorbing capacity. For this reason LS-DYNA3D has been used for analyzing impact collapse characteristics on hat shaped section member with respect to the valuables; thickness, width ratio and spot weld potch on impact load(7.19m/sec, 1034J). By comparing the results from simulation and the experimental results, the utilization of simulation has been certified.

  • PDF

경량화용 혼성 알루미늄 CFRP 사각튜브의 축 압궤특성 (Axial Collapse Characteristics of Combined Aluminum CFRP Square Tubes for Light-Weight)

  • 이길성;차천석;정진오;양인영
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 2004년도 추계학술대회 논문집
    • /
    • pp.110-113
    • /
    • 2004
  • Aluminum and CFRP tube is light-weight material representatively but collapse mechanism is different under axial loading. Aluminum tube absorbs energy by stable plastic deformation under axialloading. While CFRP(Carbon Fiber Reinforced Plastics)tube absorb synergy by unstable brittle failure but its specific strength and stiffness is higher than that of aluminum tube. In this study, for complement of detect and synergy effect by combination with the advantages of each member, the axialcollapsetests were performed for combined aluminum CFRP tubes which are composed of aluminum tubes wrapped with CFRP out side aluminum square tubes. Collapsecharacteristics were analyzed for combined square tubes which have different CFRP orientation angle and thickness. Test results were compared with that of aluminum tubes and CFRP tubes.

  • PDF

경량화용 Al/CFRP원형 부재의 축 압궤거동에 관한 연구 (A Study on the Axial Crushing Behavior of Aluminum Cm Circular Members for light-weight)

  • 이길성;차천석;양인영
    • 한국자동차공학회논문집
    • /
    • 제13권5호
    • /
    • pp.50-56
    • /
    • 2005
  • Aluminum member absorbs energy by stable plastic deformation under axial loading. While CFRP(Carbon Fiber Reinforced Plastics) member absorbs energy by unstable brittle failure but its specific strength and stiffness is higher than those of aluminum member. In this study, for complement of detects and synergy effect by combination with the advantages of each member, the axial collapse tests were performed for aluminum CFRP members which are composed of aluminum members wrapped with CFRP outside aluminum circular members. Based on the respective collapse characteristics of aluminum and CFRP members, crushing behavior and energy absorption characteristics were analyzed for aluminum CRRP members which have different CFRP fiber orientation angle and thickness Test results showed that aluminum CFRP members supplemented the unstable brittle failure of CFRP members due to ductile nature of inner aluminum members. It turned out that the CFRP fiber orientation angle and thickness influence energy absorption capability together with the collapse mode of the members.

손상된 흰쥐의 좌골신경에 저출력 레이저 조사후 전기생리학적 변화 (Electrophysiological Changes after Low-Power Infrared Laser Irradiation on Injured Rat Sciatic Nerves)

  • 배춘식;신수범;김권영
    • 생명과학회지
    • /
    • 제16권1호
    • /
    • pp.114-119
    • /
    • 2006
  • 저출력 적외선 레이저가 손상된 말초신경의 재생에 미치는 영향을 알아보기 위하여 흰쥐의 양측 좌골신경에 압궤손상을 준 뒤, 레이저 조사 기간에 따라 1, 3, 5 및 7주군으로 나누어 손상된 좌골신경의 신경전도속도와 진폭을 측정하여 신경재생의 정도를 관찰한 결과는 다음과 같았다. 좌골신경전도속도 검사에서 압궤손상 유발후에 손상전보다 유의하게 전도속도가 지연되었으나, 레이저를 조사한 실험측은 치료후 3주에 현저하게 신경전도 속도가 증가하였다. 좌골신경 진폭 검사에서 압궤손상 유발후에 손상전보다 유의하게 진폭이 감소하였으나, 레이저를 조사한 실험측은 치료후 3주에 복합근 활동전위의 진폭이 유의하게 증가하였다. 이상의 결과로 보아, 저출력 레이저 조사는 손상된 좌골신경의 기능회복에 있어, 주로 손상 초기의 회복속도에 영향을 주는 것으로 생각되는 바, 향후 말초신경 손상의 재활치료에 고려해야 할 것으로 생각된다.