• Electronics and Telecommunications Trends
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• v.28 no.4
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• pp.23-34
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• 2013

X-선 혹은 감마선 등 종래의 방서선 치료는 양성자 혹은 이온에 의한 치료방법의 등장함에 따라 퇴조할 것으로 보인다. 그 이유는, 양성자 등 전하를 띄는 입자치료기술이 치료 후 후유증이나 암의 재발을 현저히 억제시킬 수 있기 때문이다. 전하를 띄는 입자는 암 조직 전후의 정상 조직에 최소한의 피폭을 주나, X-선이나 감마선과 같은 광자들은 암 조직 전후의 정상세포가 암세포로 변화될 수 있는 정도의 피폭량을 주는 것으로 알려져 있다. 현재 임상 중인 양성자(혹은 극히 일부의 탄소이온 치료기)치료기는 1990년 미국의 로마린다(Loma Linda) 대학에서 최초로 건립된 방식인 사이클로트론 혹은 싱클로트론 가속기와 빔라인 및 겐트리(gantry)로 구성된다. 그 장치의 거대함만큼이나 가격과 유지비 등에서 일반 소형병원에서 운영하기에는 쉽지 않아 보인다. 이에 본고에서는 소형병원에서도 운영할 수 있는 저비용의 레이저 양성자(이온) 가속방식의 등장 배경과 향후 전망을 논하고자 한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.1
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• pp.54-60
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• 2001

The treatment of maxillary cancer has been commonly performed by the surgery and radiation therapy, alone or in combination. Multimodal treatment has been introduced with improvement of chemotherapy and immunotherapy. Multimodal treatment for the maxillary cancer is composed of surgery, radiation therapy, and regional intra-arterial chemotherapy. The present study was performed to evaluate the effectiveness of the multimodal treatment with Morita's method, with a slight modification, for the maxillary cancer. Twenty-four cases of the maxillary cancer were analyzed. The multimodal treatment increased the 5-year-survival rate up to 66% and reduced the need for maxillectomy. This method made the morphological and funtional preservation possible. This method may be recommended for the treatment of maxillary cancer.

• 건강소식
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• v.38 no.2
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• pp.14-15
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• 2014

암 경험자 130만 시대다. 우리나라 인구 45명 중 1명이 암에 걸린 적이 있거나 치료를 받고 있다는 의미다. 자연히 암에 대한 정보도 차고 넘친다. 문제는 잘못된 암 정보. 맞지 않은 정보는 자칫 암을 악화시키는 지름길이 될 수 있다는 것. 암에 대한 대표적인 오해와 진실을 가려 보자.

• Journal of Hospice and Palliative Care
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• v.11 no.4
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• pp.175-180
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• 2008

진행된 암환자에서 피로는 70% 이상이 경험하게 되는 흔한 증상이며 삶의 질을 저하시키는 주된 요인이다. 피로에 대한 선별검사는 "피곤하거나 지친감이 있나요?"라는 단순한 질문으로 가능하며 이미 개발된 평가도구를 사용하여 평가할 수 있다. 동반 질환이나 피로의 원인을 알기 위한 병력청취와 검사실 검사가 필요할 수 있으며 결과에 따라 가역적 인자를 치료하는 과정이 우선되어야 한다. 적절한 약물치료를 시행하여 증상을 호전시킬 수 있으며 이중 methylphenidate는 암 연관 피로를 호전시키고 마약성 진통제에 의한 진정에 효과가 입증되었다. 환자의 여명에 따라 부신 피질 호르몬제도 사용할 수 있고, 운동 및 환자의 교육과 영양관리 또한 중요하다.

• Journal of Korean Traditional Oncology
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• v.28 no.1
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• pp.33-44
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• 2023

목적: 항암유발말초신경병증은 암 환자가 겪는 흔한 항암 부작용이나 현재까지 효과적으로 알려진 치료법은 없다. 본 연구의 목적은 항암유발말초신경병증에 대한 침 치료와 가바펜틴의 병용 요법의 효과와 안전성을 평가하는 것이다. 방법: 항암유발말초신경병증을 겪고 있는 24명의 암 환자를 침 치료 단독군 (AG, acupuncture group)과 침과 가바펜틴의 병용요법군 (CG, combined acupuncture and gabapentin group)으로 무작위 배정하였다. 두 그룹 모두 침 치료는 주 3회, 4주간 수행하였다. 병용 요법군은 침 치료와 더불어 1일 900mg의 가바펜틴을 복용하도록 하였다. 치료 효과는 Neuropathic Pain Symptom Inventory (NPSI), visual analogue scale (VAS), European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy 20 items (EORTC-CIPN20)를 이용하여 측정하였다. 치료로 인한 부작용은 대상자가 방문할 때마다 조사하였다. 결과: 총 23명의 대상자(AG, n=12; CG, n=11)의 평가지표를 분석한 결과, 치료 4 주 후 침 치료 단독군은 NPSI 점수가 44.33±25.04에서 30.58±21.55으로 감소하였고, 병용 요법군은 30.55±25.59에서 18.64±19.42로 감소하였으며, 두 군 모두 통계적으로 유의미하게 감소하였다(p<0.001). VAS점수는 침 치료 단독군에서는 4.79±2.17 에서 3.42±2.49으로 감소하였고, 병용 요법군에서는 3.55±2.07에서 2.73±2.49 로 감소하였다(p<0.05). 치료 효과는 치료 완료 2주후까지 지속되었으며, 두 군간의 유의미한 차이는 없었다. EORTC-CIPN20은 침 치료 단독군은 30.27±18.87에서 20.84±16.35으로 감소하여(p<0.01), 두 군 모두에서 삶의 질이 향상되었다. 결론: 본 연구로 침 치료와 가바펜틴의 병용 요법이 항암유발말초신경병증 환자의 증상 및 삶의 질 개선에 효과적이며 안전한 치료법임을 확인하였다. 그러나 침 치료와 가바펜틴의 시너지 효과에 대해서는 확인 할 수 없었으며, 이를 확인하기 위해 추가적인 연구가 필요할 것으로 사료된다.

• Radiation Oncology Journal
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• v.26 no.4
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• pp.229-236
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• 2008

Purpose: The purpose of this study was to evaluate the impact of the use of external radiation therapy (ERT) in terms of survival and compliance in patients with anaplastic thyroid carcinoma. Materials and Methods: The medical records of 17 patients with anaplastic thyroid carcinoma treated with ERT between 1993 and 2002 were retrospectively reviewed. ERT was administered after surgery in 14 patients and after a biopsy in three patients. Among the 14 patients who had undergone surgery, nine underwent a curative resection and five underwent a palliative resection. Six patients had associated well-differentiated thyroid carcinomas and 14 patients were diagnosed with a tumor size exceeding 5 cm. The radiation dose ranged from $6{\sim}70\;Gy$ (median dose, 37.5 Gy). Eleven patients completed the planned course of ERT, whereas six patients did not. The follow-up period ranged from $1{\sim}104$ months (median, 5 months; mean, 20 months). Results: Five patients started the ERT without the presence of a gross mass and all of the patients competed ERT without a re-growth of tumor. Twelve patients (four patients after a curative resection, five patients after a palliative resection and three patients after a biopsy) started ERT with a gross mass present and only six patients were able to complete the planned course of ERT. Among the six patients who completed ERT, two patients showed a marked regression of the tumor mass, whereas two patients showed slight regression and two patients showed no response. The median survival was five months (range, $1{\sim}104$ months) and the mean survival was 21 months. The overall survival was 41% at 1-year, 24% at 2-years and 12% at 5-years. Significant prognostic factors included the number of primary tumors present, tumor size, whether surgery was performed and completion of ERT as planned. Long-term survivors showed a tendency of having smaller sized initial tumors and smaller sized pre-ERT tumors than the short-term survivors. Conclusion: This study suggests that patients with a small initial tumor (${\leq}5\;cm$), which was treated by surgery (curative resection or palliative resection) before ERT, and without rapid re-growth of the mass seen at the surgical site at the beginning of the ERT course, would be the best candidates for postoperative ERT. In contrast, patients with a large initial tumor (>5 cm) and did not undergo surgery before ERT or that rapid re-growth of the mass was observed at the surgical site are likely to have a short survival time, along with the interruption of ERT. In these cases, the role of ERT is very limited and the omission of ERT could be considered.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.215-225
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• 2016

The purpose this study was to explore the return-to-work experience of nurses after receiving cancer treatment. The participants of this research were 6 registered nurses who were working when they were diagnosed with cancer. Data were collected by individual in-depth interviews from January 5 to January 29, 2016 and analyzed using phenomenological methodology by Colaizzi(1978). The study results revealed that the return-to-work experiences of nurses after receiving cancer treatment may be categorized as 'Enduring hardly', 'Living a balance in my turning point', 'Reborn' and may be identified with 9 theme clusters and 27 themes. Their experience of returning to work as a nurse after cancer treatment consisted of expressing difficulty in handling both work and treatment. Despite that, they came to live a more mature life after their disease and came to affirm their existence through their work. Thus, an improved working environment to manage both work and treatment and continual support and assistance from society is deemed necessary.

• Proceedings of the Materials Research Society of Korea Conference
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• 2007.11a
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• pp.152.2-152.2
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• 2007

• The Science & Technology
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• no.4 s.407
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• pp.64-66
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• 2003

양성자 가속기가 암치료의 희망으로 떠오르면서 국내개발이냐, 수입이냐를 놓고 논란이 계속되고 있는 가운데 국산화를 강하게 주장하는 주동일 박사를 만나 양성자치료 장치의 효능과 국산 개발 주장의 근거를 들어봤다.

• Radiation Oncology Journal
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• v.22 no.3
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• pp.184-191
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• 2004

Purpose: In order to improve the proper use of radiotherapy and breast-conserving treatment (BCT) in the management of breast cancer, current status of breast cancer treatment in Korea was surveyed nationwide and the use of BCT were evaluated. Materials and Methods: Patients characteristics and treatment pattern of 1048 breast cancer patients from 27 institutions diagnosed between January, 1998 and June, 1998 were analyzed. The incidence of receiving BCT was analyzed according to the stage, age, geography, type of hospital, and the availability of radiotherapy facility. Results: Radical mastectomy was peformed in 64.8$\%$ of total patients and 26$\%$ of patients received breast- conserving surgery (BCS). The proportions of patients receiving BCT were 47.5$\%$ in stage 0, 54.4$\%$ in stage I, and 20.3$\%$ in stage II, Some of the patients (6.6$\%$ of stage I, 10.1$\%$ of stage II and 66.7$\%$ of stage III) not received radiotherapy after BCS. Only 45$\%$ of stage III patients received post-operative radiotherapy after radical mastectomy. The proportion of patients receiving BCT was different according to the geography and availability of radiotherapy facilities. Conclusion: Radiotherapy was not fully used in the management of breast cancer, even in the patients received breast-conserving surgery. The proportion of the patients who received BCT was lower than the report of western countries. To improve the application of proper management of breast cancer, every efforts such as a training of physicians, public education, and improving accessibility of radiotherapy facilities should be done. The factors predicting receipt of BCT were accessibility of radiotherapy facility and geography. Also, periodic survey like current research is warranted.