• Title/Summary/Keyword: 암센터

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A Study of Environmental Conditions of Survival Rate and Relative Growth Rate in Female Gametophyte of Undaria pinnatifida for Toxicity Assessment (생태독성평가를 위한 미역(Undaria pinnatifida) 암배우체 생존율 및 상대성장률의 환경조건 연구)

  • Ju-Wook, Lee;Yun-Ho, Park;Bo-Ram, Sim;Hyong-Joo, Jeon;Seung, Heo;Un-Ki, Hwang
    • Journal of Marine Life Science
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    • v.7 no.2
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    • pp.86-93
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    • 2022
  • The ecotoxicity test method using Undaria pinnatifida spore is challenging to use throughout the year. Since U. pinnatifida female gametophytes can be cultured in the laboratory, they can be used for ecotoxicity testing at any time. Changes in female gametophyte survival rate and relative growth rate in U. pinnatifida exposed to various environmental conditions were analyzed. The female gametophyte of U. pinnatifida was exposed to salinity (5~40 psu), temperature (5~30℃), pH (4~10), and light intensity (0~120 μmol photon m-2 s-1). Based on the highest average value, the survival rate of female gametophyte was highest at a temperature of 20℃, salinity 27.5 psu, pH 8, and light intensity 30 μmol photon m-2 s-1. And the relative growth rate was highest at a temperature of 15℃, salinity 35 psu, pH 9, and light intensity of 60 μmol photon m-2 s-1. As a result of this study, the method using the optimal conditions for the survival rate and relative growth rate is expected to be a practical test method that can complement the current method.

Effects of Neuromuscular Electrical Stimulation on Muscle Wasting with Cancer Patient: Study Protocol for a Systematic Review (신경근전기자극치료가 암환자의 근육 손실에 미치는 영향: 체계적 문헌고찰을 위한 프로토콜)

  • Eun Soo Park;Jong Hee Kim;Soo Dam Kim;Dong Hyun Kim;Min Seok Oh;Eun Jung Lee;Hwa Seung Yoo
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.2
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    • pp.49-55
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    • 2023
  • Objectives The purpose of this study is to analyze randomized controlled trials about neuromuscular electrical stimulation for muscle wasting with cancer patient and evaluate it's motor functionality effect. Methods Studies will be searched from 7 online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI], Korean studies Information Service System [KISS], Research Information Sharing Service [RISS], Oriental Medicine Advanced Searching Integrated System [OASIS]). Participants will be cancer patients with muscle loss, regardless of cause, gender, race or age, interventions will be neuromuscular electrical stimulation. Other treatments than interventions will be the control group and the main outcome will be reviewed by motor functionality effect. Results Randomized controlled trials about neuromuscular electrical stimulation for muscle wasting should be included in the study. Primary outcomes include motor functionality effect. Secondary outcomes evaluate adverse event. The data uses Review Manager Software 5.4. Conclusions The conclusion of this study will provide a basis for determining whether neuromuscular electrical stimulation treatment for muscle wasting with cancer patient treatment is an effective and safe treatment method in clinical practice.

Cancer cluster detection using scan statistic (스캔 통계량을 이용한 암 클러스터 탐색)

  • Han, Junhee;Lee, Minjung
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.5
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    • pp.1193-1201
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    • 2016
  • In epidemiology or etiology, we are often interested in identifying areas of elevated risk, so called, hot spot or cluster. Many existing clustering methods only tend to a result if there exists any clustering pattern in study area. Recently, however, lots of newly introduced clustering methods can identify the location, size, and shape of clusters and test if the clusters are statistically significant as well. In this paper, one of most commonly used clustering methods, scan statistic, and its implementation SaTScan software, which is freely available, will be introduced. To exemplify the usage of SaTScan software, we used cancer data from the SEER program of National Cancer Institute of U.S.A.We aimed to help researchers and practitioners, who are interested in spatial cluster detection, using female lung cancer mortality data of the SEER program.

Knowledge Structure of Posttraumatic Growth Research: A Network Analysis (네트워크 분석을 통한 외상 후 성장 지식구조 연구)

  • Shin, JooYeon;Kwon, Sunyoung;Bae, Ka Ryeong
    • Journal of Industrial Convergence
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    • v.20 no.10
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    • pp.61-69
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    • 2022
  • Posttraumatic growth literature has been rapidly expanding in multiple academic disciplines. Purpose of this study is to examine the knowledge structure of posttraumatic growth utilizing a network analysis. Papers published between 1996 and 2018 were searched on the Web of Science, focusing on terms related to posttraumatic growth. One thousand six-hundred and fifty-nine keywords were published 6,343 times in 1,780 papers; thus, a total of 322 keywords (5,195 appearances) were selected for the final analysis. The network analysis and network visualization tool used were NodeXL and PFnet, respectively. The keywords which appeared the most frequently were "Posttraumatic growth," followed by "Posttraumatic Stress Disease," "Cancer," and "Trauma." A total of 322 nodes have been reduced to 175 nodes and divided into a total of five groups. The five groups were "Posttraumatic Growth in Cancer, Chronic/Serious Illness, and Disability," "Posttraumatic Growth-related Psychological Variables and Psychotherapy," "Posttraumatic Growth in the Context of Death," "Cognitive Mechanisms of Posttraumatic Growth," and "Vicarious Posttraumatic Growth." This study provides a systematic overview on the knowledge structure of posttraumatic growth by quantitatively network analysis.

Eating patterns and use of nutritional information in breast cancer survivors treated with radiation therapy in South Korea (일반인과 유방암 환자간의 식행동 및 영양정보에 관한 인식조사)

  • Kim, Kyoung-Ok;Park, Hyunjin;Chun, Mison;Lee, Eun Hyun;Kim, Hyun-Sook
    • Journal of Nutrition and Health
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    • v.46 no.3
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    • pp.250-260
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    • 2013
  • The purposes of this study were 1) to investigate eating behaviors and patterns in breast cancer patients using a newly developed food frequency questionnaire and 2) to examine perception and use of nutritional information about breast cancer treatment among cancer patients treated with radiation therapy. Sixty breast cancer patients (case group) undergoing radiation therapy in Ajou University Hospital, Suwon, South Korea and 79 healthy women (control group) participated in this study. Mean age of subjects in the control group was $46.00{\pm}7.88$ years and BMI was $23.12{\pm}2.85kg/m^2$, and that of the case group was $50.06{\pm}11.64$ years and $22.32{\pm}3.24kg/m^2$. The results of eating behaviors showed several significant differences between control and case groups. Breast cancer patients ate meals on a more regular basis, on time, and more frequently compared to control subjects. In addition, they preferred more salty or spicy and bland food compared to healthy women. According to answers from the food frequency questionnaire, breast cancer patients consumed significantly lower amounts of boiled white rice, meats and processed food, fish and shellfish, coffee, milk, and cheese, whereas they consumed a significantly large amount of boiled multigrain rice, vegetable, seaweeds, soybean and processed food, and yoghurt compared to healthy women. This study also observed the way in which cancer patients and healthy control subjects obtain information about breast cancer treatment and its reliabilities. Results showed that healthy women did not hesitate to obtain information from mass media, while breast cancer patients would obtain nutritional information from specialists rather than mass media. Results of this survey confirmed that breast cancer patients avoided intake of red meat protein, even though they already recognized the importance of dietary protein intake for recuperation and treatment of the disease. These results could be used for future diet and nutrition guidelines for breast cancer patients.

Generation of Collaboration Network and Analysis of Researcher's Role in National Cancer Center (협업네트워크 구축과 연구자 역할 분석 -국립암센터 사례 중심으로-)

  • Jang, Hae-Lan
    • The Journal of the Korea Contents Association
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    • v.15 no.10
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    • pp.387-399
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    • 2015
  • Recently collaboration network is generated to find out experts in their field as potential collaborators in health care sector. In this paper, the co-author network of a National Cancer Center researcher was generated for identifying each researcher's role and collaborative research pattern. The co-author network of 2,437 authors was extracted from 1,194 SCI(E) publications from 2000 to 2010 and author's role was analyzed by author's centrality value. Centrality reflecting only the number of papers and centrality weighted by the paper number, impact factor, and authorship contribution was evaluated. On the comparison with simple degree centrality value and the weighted degree centrality, difference of value was statistically significant(t=11.66, p=0.00). Co-author network considering various variables of the paper provides more objective figure of researcher's role. This suggests that co-author network could be more effective in identifying potential collaborators.

Relationship Between Health Promoting Lifestyle and General Characteristics of the Person Undergoing Health Checkups in Cancer Prevention Center (암예방 센터 건강검진자의 건강증진 생활양식)

  • Hyun, Kyung-Sun;Kang, Jung-Mi;Park, Young-Mi
    • Journal of East-West Nursing Research
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    • v.14 no.1
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    • pp.14-23
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    • 2008
  • Purpose: The purpose of this study was to identify the relationship between health promoting lifestyle and general characteristics of the person undergoing health checkups in cancer prevention center. Method: A cross-sectional survey was used. This study has been done from February 1 to March 31, 2005 and the subjects of the study were 199 persons who had undergone health checkups in Cancer Prevention Center located in Seoul. Data were collected by using self reporting questionnaire on the health promoting lifestyle. The collected data were analyzed by using t-test, ANOVA, and Pearson's correlation coefficient. Result: The average score of performance in the health promoting lifestyle was 162.99(range of score is 60-240). There were significant differences in scores of health promoting lifestyle according of marital status, age, education and smoking. The score of health promoting lifestyle of the married group was higher than that of the single group. The score of health promoting lifestyle was higher in those aged 60-69 years than in those aged 20-29 years. As compared to college graduates the score of health promoting lifestyle was higher among those whose schooling is less than middle school and higher than a master`s program. The score of health promoting lifestyle was higher among non-smokers than among those who used a cigarette in their life time. There were no differences in scores of health promoting lifestyle according to sex, cancer family history, disease family history and drinking.There was positive relationship between age and health promoting lifestyle. Conclusion: Marital status, age, education and smoking affected Health Promoting Lifestyle of the person undergoing health checkups in Cancer Prevention Center.

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Tracheostomy Performed by a Head and Neck Surgeon Under the Supervision of an Intensive Care Unit Specialists in the COVID-19 Era: A Retrospective Analysis (COVID-19 시대에 중환자실 전담의사 감독 하에 두경부 전문의에 의해 시행된 기관절개술에 대한 후향적 분석 연구)

  • Han, Won Ho;Lee, Yun Im;Baek, Sunhwa;Seok, Jungirl
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.33 no.2
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    • pp.97-102
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    • 2022
  • Background and Objectives Tracheostomy is a relatively safe procedure, and the recent emergence of COVID-19 has raised the need to perform tracheostomy immediately in the bed of an intensive care unit (ICU) rather than an operating room. The purpose of this study was to determine the occurrence of complications related to surgical tracheotomy performed in the ICU by an ENT specialist. Materials and Method From March 2019 to January 2022, a total of 101 patients underwent tracheostomy in the ICU. Demographics and complications were classified according to postoperative period. Results Within 24 hours after the procedure, bleeding events were confirmed in 2 patients (2.0%) with mild bleeding. One case (1.0%) of ventricular fibrillation occurred shortly after the procedure. There were no complications from 24 hours to 1 week after procedure. After one week, 4 patients (4.5%) had a local infection, and 3 patients (3.4%) had a tube obstruction. During all follow-up periods, there were no serious side effects such as death, major vascular injury, pneumothroax. No complications were observed throughout the entire period in 6 COVID-19 patients. Conclusion The number of complications of surgical tracheotomy in the ICU performed by a specialist was lower than in previous studies, and there were no complications that delayed treatment or endangered life. The ENT training hospitals should provide sufficient training opportunities for residents to perform surgical tracheostomy and strive to minimize complications associated with the procedure and pre- and post-operative management under the detailed guidance and supervision of specialists.

A Study on Predictive Modeling of I-131 Radioactivity Based on Machine Learning (머신러닝 기반 고용량 I-131의 용량 예측 모델에 관한 연구)

  • Yeon-Wook You;Chung-Wun Lee;Jung-Soo Kim
    • Journal of radiological science and technology
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    • v.46 no.2
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    • pp.131-139
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    • 2023
  • High-dose I-131 used for the treatment of thyroid cancer causes localized exposure among radiology technologists handling it. There is a delay between the calibration date and when the dose of I-131 is administered to a patient. Therefore, it is necessary to directly measure the radioactivity of the administered dose using a dose calibrator. In this study, we attempted to apply machine learning modeling to measured external dose rates from shielded I-131 in order to predict their radioactivity. External dose rates were measured at 1 m, 0.3 m, and 0.1 m distances from a shielded container with the I-131, with a total of 868 sets of measurements taken. For the modeling process, we utilized the hold-out method to partition the data with a 7:3 ratio (609 for the training set:259 for the test set). For the machine learning algorithms, we chose linear regression, decision tree, random forest and XGBoost. To evaluate the models, we calculated root mean square error (RMSE), mean square error (MSE), and mean absolute error (MAE) to evaluate accuracy and R2 to evaluate explanatory power. Evaluation results are as follows. Linear regression (RMSE 268.15, MSE 71901.87, MAE 231.68, R2 0.92), decision tree (RMSE 108.89, MSE 11856.92, MAE 19.24, R2 0.99), random forest (RMSE 8.89, MSE 79.10, MAE 6.55, R2 0.99), XGBoost (RMSE 10.21, MSE 104.22, MAE 7.68, R2 0.99). The random forest model achieved the highest predictive ability. Improving the model's performance in the future is expected to contribute to lowering exposure among radiology technologists.

A Survey on Korean Medicine Doctors' Recognition for Developing Korean Medicine Clinical Practice Guidelines for Gastric Cancer (위암 한의표준임상진료지침 개발을 위한 한의사 인식조사)

  • Dong-hyeon Kim;Jong-hee Kim;Ji-hye Park;Hwa-seung Yoo;So-jung Park
    • The Journal of Internal Korean Medicine
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    • v.44 no.3
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    • pp.466-484
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    • 2023
  • Objective: The purpose of this study was to provide data for the development of Korean medicine (KM) clinical practice guidelines (CPG) for gastric cancer (GC) by identifying the awareness and knowledge needs of KM doctors (KMD) through an online survey. Methods: A survey questionnaire was produced by referring to the previous recognition survey studies for clinical KMDs. The survey questionnaire was composed of questions regarding the current status of clinical care for GC, the knowledge level of clinicians about GC, and other details that clinicians use during practice. The survey was conducted from September 20 to October 22, 2021. An online survey was conducted with 195 KMDs from the Society of Korean Medicine and the Korean Association of Traditional Oncology of KM. Results: A total of 195 respondents participated in the online survey regarding the current status of GC treatment. Of this number, 10.3% of the respondents specialize in GC, but even if they do not currently specialize in GC, they are more likely to treat patients with GC in the future. In terms of the specifics of KM treatment, there was a demand for information on comprehensive KM treatment methods, such as herbal medicine, acupuncture, moxibustion, cupping, and chuna, as well as on analyzing the effectiveness of combined treatment with chemotherapy and radiation. Conclusion: In this study, we were able to understand the clinical KMDs' perception of GC, knowledge level, and requirements in the CPG. The results of this study will provide the basic data for the development of CPG for GC.