• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.9
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• pp.1387-1394
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• 2013

Allergies are one of the most common chronic diseases during childhood. While the prevalence of allergic disease in children is increasing dramatically, few studies have evaluated the risk and preventive factors related to this health condition, especially in South Korea. The purpose of this case-control study was to evaluate independent determinants of allergic disease, and to examine whether it is associated with growth and other health conditions in childhood. The current study included 209 cases and 311 age and sex-matched controls (fifth and sixth graders) residing in Daegu, South Korea. Environmental data was collected, including child and family histories of allergies, birth information, and reaction to weaning foods during infancy. In addition, current dietary habits (assessed by 2 day-24 hr food records), health conditions, and anthropometric data were obtained through questionnaires and student health check-ups at the school. Based on chi-square tests, cases had a significantly higher prevalence of having a disease at birth, an allergic reaction to weaning foods, frequent hospital visits, and frequent experiences of the common cold and digestive diseases. In addition, significantly more mothers had a higher education in the cases compared to controls. Based on multivariable conditional logistic regression analysis, factors significantly associated with greater odds for having allergies were parental (OR=21.42) and fraternal (OR=14.40) histories of allergies. The anthropometric measures showed that cases tended to be shorter in height and lighter in weight than the controls, but these differences were not statistically significant. These findings may indicate that current nutrient intakes may not be the only critical factor associated with delayed growth delay in the allergic group. A well-planned, large cohort study is warranted to confirm our findings in the future.

• Clinical and Experimental Pediatrics
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• v.49 no.10
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• pp.1061-1066
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• 2006

Purpose : The purpose of this study was to research whether measurement of cow's milk specific IgE on the newborn would be helpful in the diagnosis of cow's milk allergy. We tried to find out the relation between cow's milk specific IgE and other allergy diseases by following up cases. Methods : We reviewed clinical features of 87 episodes in infants less than 4 weeks old who were positive in cow's milk specific IgE test. For the study group, history taking, physical examinations, elimination and cow's milk specific IgE tests were carried out. We investigated the connection among cow' milk specific IgE, allergic disease and family history in 40 of 87 patients we could follow up on. Results : The mean age of the study group was $17.2{\pm}5.4days$. The subjects were classified in four groups according into allergens : 87 milk allergy positive patients, 24 casein positive, 38 ${\alpha}$-lactoalbumin positive, and 75 ${\beta}$-lactoglobulin positive. The number of patients who had follow-ups for more than 6 months to was 40(45.9 percent). The patients whose parents had allergic disease numberred 10(25 percent). Fiften patients had allergic diseases, 4 had asthma and 11 atopic dermatitis. According to the follow-up study, there is a significant relation between casein positive patients and allergic disease. But there is no statistical and significant relation between cow's milk specific IgE and a family history of allergic disease. Conclusion : For the newborn babies, elimination tests and cow's milk specific IgE tests can be useful in the diagnosis of IgE-mediated or mixed milk allergies.

• Bulletin of Korea Environmental Preservation Association
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• s.414
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• pp.19-22
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• 2014

환경성질환은 19세기 이후 산업화 등으로 인한 특정 물질 등으로 인한 오염이 집중, 심화되면서 그 악영향에 대한 관심 및 중요성이 더욱 커지고 있는 실정이다. 대표적인 환경성질환인 아토피피부염, 알레르기비염, 천식 등 알레르기질환이 지속적으로 증가하는 추세이며, 특히 면역력이 약한 어린이, 청소년 및 노인층을 중심으로 꾸준히 발생하고 있어, 이에 대한 예방관리에 더욱 더 많은 관심을 기울일 필요가 있다.

• Clinical and Experimental Pediatrics
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• v.51 no.6
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• pp.640-645
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• 2008

Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire. Results : A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease. Conclusion : In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.2
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• pp.102-108
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• 2016

Der p 2 is the major allergen of the house dust mite (HDM) associated with the development of allergic diseases. The pathogenic mechanism of the allergy is related to cytokine release of lymphocytes and constitutive apoptosis of neutrophils. In the present study, we examined whether Der p 2 induces cytokine release of lymphocytes, which is involved in regulation of neutrophil apoptosis. In normal and allergic subjects, Der p 2 enhanced the secretion of IL-6, IL-8, MCP-1, and GM-CSF in a time-dependent manner. Although Der p 2 was weakly effective against neutrophil apoptosis, conditioned media collected from normal and allergic lymphocytes after Der p 2 treatment inhibited the apoptosis of normal and allergic neutrophils. Der p 2 showed stronger inhibition of apoptosis of allergic neutrophils cocultured with allergic lymphocytes than normal neutrophils cocultured with normal lymphocytes. These findings improve our understanding of the role of Der p 2 in regulation of lymphocytes and neutrophils and will enable elucidation of allergy pathogenesis.

• 건강소식
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• v.36 no.10
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• pp.20-20
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• 2012

가을에는 일교차가 커지면서 차고 건조해진 공기에 알레르기비염과 천식 등 알레르기 질환이 쉽게 발생한다. 특히 알레르기비염의 주요 원인은 집먼지 진드기나 곰팡이, 애완동물의 털, 꽃가루 등이다. 그렇다면 집안 곳곳 숨어있는 곰팡이와 진드기를 예방하고 제거할 수 있는 방법은 무엇일까?

• Journal of Industrial Convergence
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• v.18 no.5
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• pp.70-76
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• 2020

The purpose of this study was to determine the dietary behavior of adolescents and to determine the association with allergic diseases according to dietary behavior. The data were obtained from the 15th Korea Youth Risk Behavior Survey 2019. Complex-sample descriptive statistics and the chi-square test were used for data analysis in SPSS. Adolescents diagnosed with asthma had a relationship with frequency of breakfast, fruit, soda, energy drink, sweet drink, fast food, vegetable and convenience store eating experience. Adolescents diagnosed with allergic rhinitis were associated with frequency of breakfast, fruit, soda, sweet drinks, vegetables, and milk. Adolescents diagnosed with atopic dermatitis were associated with soda, vegetables, milk, and convenience store eating experiences. Therefore, in the case of adolescents with allergic diseases, it is necessary to educate them on correct dietary behavior so that they can have correct habits.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.347-353
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• 2019

This study was a descriptive research to investigate the difference of obesity, smoking, drinking affected allergy disease in Korean adolescents using the raw data of $6^{th}$ Korea National Health and Nutrition Survey(2015). Study data on 535 Korean adolescents classified 12 to 18 years and Rao-Scott Chi-square test and logistic regression were used for analysis. The results of the study showed that the prevalence of asthma, atopic dermatitis, allergic rhinitis were 5.4%, 15.5%, 22.8% and not shown differences according obesity, smoking, drinking. But, the risk factor of asthma was related obesity, atopic dermatitis was related smoking. Based of this study's findings, It is necessary to develop the Heath Promotion Intervention Program according of obesity, drinking, smoking for the quality of life in adolescents diagnosed Allergy disease.

• 식품문화 한맛한얼
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• v.4 no.3
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• pp.314-319
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• 2011

최근 알레르기 질환의 빈도가 많이 증가하였고, 그 중 식품알레르기(Food Allergy)는 소아 연령에서 많이 발생하고 있다. 병원에서 진단 후에는 치료 과정 중에서 식품회피(알레르기 유발 식품을 피하는 것)는 필수적이라 성장기의 소아, 청소년에게는 영양적 문제와 성장부진 등 합병증을 유발할 가능성이 있다. 그렇기 때문에 영양적 문제와 성장부진 문제를 예방하기 위해서는 우선, 의사의 정확한 진단이 필수적이다. 그 다음으로 무분별하고 과다한 식품 제한을 막고, 성장 시기에 맞는 영양관리가 필요하다.

• Journal of Industrial Convergence
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• v.22 no.7
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• pp.81-91
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• 2024

This study was conducted to determine the status of allergic diseases and mental health in adolescents, confirm the relationship between allergic diseases and mental health, and provide basic data for developing effective disease management measures for adolescents at the developmental stage. Secondary analysis was performed on the data from the 17^th Youth Health Behavior Online Survey, and complex sample descriptive statistics, cross-tabulation, and logistic regression analysis were performed using the SPSS 26.0 program. As a result of the study, those with one or more allergic diseases were 1.286 times more likely to have stress (B=1.286, p<.000), 1.289 times more likely to be depressed (B=1.289, p<.000), and 1.399 times more likely to have generalized anxiety disorder (B=1.399, p<.000) was highly likely to experience it. Additionally, factors affecting the mental health of adolescents with allergic diseases were gender, economic level, academic performance, drinking experience, and smoking experience. Stress and generalized anxiety disorder were more likely to be experienced by female students, if they had a lower economic level and academic performance, and if they drank alcohol or smoked. Male students were more likely to experience depression if their economic level and academic performance were higher, and if they did not drink alcohol or smoke. Based on these results, we hope to establish a practical approach by establishing effective strategies to manage allergic diseases in adolescents and the mental health conditions that may arise from them.