• The Journal of the Korea Contents Association
• /
• v.21 no.4
• /
• pp.785-794
• /
• 2021

This study investigated the current status of the design and direction of improvement of the sign system of urban railway stations in the Seoul metropolitan area to see how difficult it is for users to use. As a research method, first, a theoretical study on the literature of the urban railway sign system, second, a survey on the current status of the sign design of the Gimpo Goldline in the Seoul metropolitan area, and third, a survey on the actual use of the sign and problems was conducted. As a result of the current status survey, the location sign is in central alignment with the font of the guide sign, and the guidance sign is in front/back alignment according to the location of the entrance and exit. The background of the font is white and the text is dark black to make it look good to the user. On the other hand, guidance sign is written in white color and background color is gray color. Currently, the Gimpo Urban Railway Guidance Sign System is newly produced and installed, but there is a lack of user design and needs design maintenance that can clearly deliver information to users.

• Journal of Life Science
• /
• v.31 no.6
• /
• pp.595-602
• /
• 2021

Human intestinal microbiota play an important role in the regulation of the host's metabolism. There is a close pathological and physiological interaction between dysbiosis of the intestinal microflora and obesity and metabolic syndrome. Akkermansia muciniphila, which was recently isolated from human feces, accounts for about 1-4% of the intestinal microbiota population. The use of A. muciniphila- derived external membrane protein Amuc_1100 and extracellular vesicles (EVs) could be a new strategy for the treatment of obesity. A. muciniphila is considered a next-generation probiotic (NGP) for the treatment of metabolic disorders, such as obesity. Faecalibacterium prausnitzii accounts for about 5% of the intestinal microbiota population in healthy adults and is an indicator of gut health. F. prausnitzii is a butyrate-producing bacterium, with anti-inflammatory effects, and is considered an NGP for the treatment of immune diseases and diabetes. Postbiotics are complex mixtures of metabolites contained in the cell supernatant secreted by probiotics. Parabiotics are microbial cells in which probiotics are inactivated. Paraprobiotics and postbiotics have many advantages over probiotics, such as clear chemical structures, safe dose parameters, and a long shelf life. Thus, they have the potential to replace probiotics. The most natural strategy to restore the imbalance of the intestinal ecosystem normally is to use NGPs among commensal bacteria in the gut. Therefore, it is necessary to develop new foods or drugs such as parabiotics and postbiotics using NGPs.

• The Korean Society of Law and Medicine
• /
• v.23 no.2
• /
• pp.119-139
• /
• 2022

Brain stimulation technology that administers electrical and magnetic stimulation to a brain has shown a significant level of possibility for treating a wide range of various neurological and psychiatric disorders. Depending on its nature, the technology is defined either as invasive or non-invasive, and deep brain stimulation (DBS) is one of the most well-known invasive brain stimulation technologies. Currently categorized as grade 4 medical device in accordance with Guideline On Medical Devices And Their Grades, a Notification of Ministry of Food and Drug Safety (MFDS), the DBS has been used as a stable treatment for several diseases. At the same time, the DBS technology has recently achieved substantial advancement, encouraging active discussions for its use from various perspectives. On the contrary, debates over legal regulation related to the use of DBS has relatively been smaller in numbers. In this context, this article aims to 1) introduce the DBS technology and its safety in setting out the tone; 2) touch upon major legal issues that would potentially rise from its use for four different purposes of treatment, clinical study, areas of non-standard treatment where no other methods are available, and enhancement; and finally 3) highlight disputes concerning common emerging issues observed in the aforementioned four purposes from the viewpoint of legal responsibility and liability of using the DBS, which are benefit-risk assessment, physicians' duty of information, patients' capacity to consent, control for device, and insurance coverage.

• Journal of Life Science
• /
• v.31 no.12
• /
• pp.1128-1141
• /
• 2021

'Angelica' is one of the most traditionally consumed medicinal herbs around Northeast Asia including Korea for treatments of various diseases or health care purposes like hematopoiesis, blood circulation for women, sedative, analgesic, and a tonic medicine etc. Angelica gigas Nakai, a Korean native species of Angelica, is clearly different from the others in containing a high concentration of active ingredients like pyranocoumarines including decursin, decursinol, and decursinol angelate. These compounds have various kinds of positive effects such as anti-tumor activity including the precaution of neutropenia occurred during anticancer drug administration, improvements of metabolic disorders, menstrual irregularity, impairment of renal function, respiration improvement, cognition-enhancement, anti-inflammatory effect, anti-oxidative effect, enhancing fertility and so forth. Thus it implies incredible potentialities in future development for foods and drugs. However, certain purity-related qualities and/or overdose in food products can cause side effects like toxicities; therefore, their safety profiles should also be considered. This review focuses on the positive and negative effects of three pyranocoumarines in Angelica gigas Nakai and some possibilities and considerations for future food and drug products development.

• Journal of the Korea Society of Computer and Information
• /
• v.27 no.2
• /
• pp.125-134
• /
• 2022

In this paper, we propose an extension method of the BR2K technique for enhancing the robustness of blockchain application services. The BR2K (Blockchain application, Replication & Recovery technique using Kubernetes) technique was recently developed to support the robustness of blockchain services through service replication and rapid restart. The proposed technique extends the existing BR2K technique to provide a state version, which is meta-information about the service state, and a method for safely managing it, and use the state version to determine the timing for service state recovery. Also, the technique provides systematic service state backup for service recovery and joining of new service nodes by utilizing the version information and the service registry which acts as a service recovery center in the BR2K technique. Based on this, it is possible to support new service nodes to join the replication service with consistency. As a result, new service nodes can be quickly added to the BR2K service in operation, enhancing the robustness of the BR2K service. In addition, the extended method is applied to the pilot blockchain application service and tested in a Kubernetes environment composed of virtual machines to confirm the validity of service replication consistency and rapid service recovery in the event of node failures.

• Korean Journal of Poultry Science
• /
• v.50 no.1
• /
• pp.51-61
• /
• 2023

This study was designed to evaluate the effects of feral peach (Prunus persica Batsch var. davidiana Max.) sugar extracts (peach extracts) and Gomchwi (Ligularia fischeri) extracts on physicochemical properties of Woorimatdag 1breast marinated with red pepper sauce during cold storage for 18 days. Experimental groups were divided into five groups; CON: marinated breast with basic red pepper sauce, GP15 and GP30: added with 15% and 30% of peach extracts into CON, respectively, GG5 and GG10: added with 5% and 10% of Gomchwi extracts into CON, respectively. Moisture and fat contents of GP30 were lower than those of CON, GG5, and GG10 (P<0.05). Cholesterol content of GP15 was similar to that of CON, while it was lower than the other treatments. GP15 and GP30 showed significantly lower pH than the others. Especially, GP30 showed significantly lower total aerobic bacteria count than other treatment on day 10. During storage, peach and Gomchwi extracts were not significantly effect on meat shear force. Overall acceptability of GP15 was higher than that of GG10 at day 10 and 15 (P<0.05). These results indicated that the treatment of peach extracts has a tendency to improve the storage stability maintaining the sensory preference of marinated Woorimatdag 1 breast compared to Gomchwi extracts. Further study would be needed to identify the specific flavor-enhancing factors of GP treatments.

• Journal of the Institute of Convergence Signal Processing
• /
• v.23 no.4
• /
• pp.200-208
• /
• 2022

In this study, an automatic information collection system and geographic information construction algorithm for the transportation disadvantaged using electric mobility aids are implemented using an object recognition model. Recognizes objects that the disabled person encounters while moving, and acquires coordinate information. It provides an improved route selection map compared to the existing geographic information for the disabled. Data collection consists of a total of four layers including the HW layer. It collects image information and location information, transmits them to the server, recognizes, and extracts data necessary for geographic information generation through the process of classification. A driving experiment is conducted in an actual barrier-free zone, and during this process, it is confirmed how efficiently the algorithm for collecting actual data and generating geographic information is generated.The geographic information processing performance was confirmed to be 70.92 EA/s in the first round, 70.69 EA/s in the second round, and 70.98 EA/s in the third round, with an average of 70.86 EA/s in three experiments, and it took about 4 seconds to be reflected in the actual geographic information. From the experimental results, it was confirmed that the walking weak using electric mobility aids can drive safely using new geographic information provided faster than now.

• Journal of Life Science
• /
• v.33 no.4
• /
• pp.371-381
• /
• 2023

Endocrine disrupting chemicals (EDCs), used in a variety of products in modern society, are hormone-like substances that cause various diseases. Humans are exposed to EDCs through their inclusion in pesticides, plastics, cosmetics, detergents, and drugs. Bisphenol A (BPA), one of the representative endocrine disruptors, is an estrogen-like substance that has been widely used commercially in plastic and epoxy resins. BPA is a chemical that can disrupt the endocrine system, leading to reduced reproductive function, obesity, cancer, and neurodevelopmental disorders. Since the adverse health effects of BPA began to be reported the use of BPA has been regulated worldwide. Various alternatives to BPA have been widely used worldwide; representatively, bisphenol S (BPS) and bisphenol F (BPF) are the most commonly used in commercial contexts. BPS and BPF may cause endocrine-disrupting effects like those of BPA due to their similar chemical structures. Recent studies have reported that BPS and BPF disrupt the neurodevelopmental process and cause neurodevelopmental disorders. Therefore, future studies will be required for safety verification of BPA alternatives and the development of new alternatives to BPA for brain health. In this review, we reviewed the effects of BPA and the alternatives, BPS and BPF, on the nervous system.

• The Journal of Bigdata
• /
• v.7 no.1
• /
• pp.15-27
• /
• 2022

In the past five years, the fatality rate of single-vehicle accidents has been 4.7 times higher than that of all accidents, so it is necessary to establish a system that can detect and respond to single-vehicle accidents immediately. The IoT(Internet of Thing)-based real-time traffic accident recognition system proposed in this study is as following. By attaching an IoT sensor which detects the impact and vehicle ingress to the guardrail, when an impact occurs to the guardrail, the image of the accident site is analyzed through artificial intelligence technology and transmitted to a rescue organization to perform quick rescue operations to damage minimization. An IoT sensor module that recognizes vehicles entering the monitoring area and detects the impact of a guardrail and an AI-based object detection module based on vehicle image data learning were implemented. In addition, a monitoring and operation module that imanages sensor information and image data in integrate was also implemented. For the validation of the system, it was confirmed that the target values were all met by measuring the shock detection transmission speed, the object detection accuracy of vehicles and people, and the sensor failure detection accuracy. In the future, we plan to apply it to actual roads to verify the validity using real data and to commercialize it. This system will contribute to improving road safety.

• The Journal of the Convergence on Culture Technology
• /
• v.9 no.5
• /
• pp.669-674
• /
• 2023

This study examined the specific contents of social welfare policies of the Joseon Dynasty through the analysis of Mokminsimseo, Aemin Sixjo and Jinhwang Yukjo, and identified the connection between them and today's social welfare policies. As a result, In the Care of the People, it contained the basic contents of the Elderly Welfare Act and welfare services for the elderly, and in the Freedom, it included welfare policy services related to infants and children, and the value system of welfare for the disabled through government affairs. The policy direction was confirmed, and it was found that disaster relief calls for social integration in response to social crises and disasters. This also confirmed that major areas of social welfare policy such as family safety, income security, health policy, and social integration have been emphasized through social welfare policy indicators. In addition, through the analysis of Qinhwangyukjo, it was found that it contains not only the basic ideology and values of the social security system and social insurance system in terms of visa, scale, and power, but also the details of specific policy implementation. Today's social welfare policies and social service policies, which are equipped with social welfare facilities and are implementing systematic social welfare services for each target, were able to confirm their foundation through the Qinhwangyukjo. This confirms that the emphasis on social integration and income security is prominent in the Qinhwangyukjo through the social welfare policy indicators of the current policy system.