• Journal of Food Hygiene and Safety
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• v.38 no.6
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• pp.430-441
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• 2023

Velvet antler is widely used as a traditional medicine, and numerous studies have demonstrated its tremendous nutritional and medicinal values including immunity-enhancing effects. This study aimed to investigate different deer velvet extracts (Sample 1: raw extract, Sample 2: dried extract, and Sample 3: freeze-dried extract) for proximate composition, uronic acid, sulfated glycosaminoglycan, sialic acid, collagen levels, and chemical components using ultra-performance liquid chromatography-quadrupole-time-of-light mass spectrometry. In addition, we evaluated the cytotoxic effect of the deer velvet extracts on BV2 microglia, HT22 hippocampal cells, HaCaT keratinocytes, and RAW264.7 macrophages using the cell viability MTT assay. Furthermore, we evaluated acute toxicity of the deer velvet extracts at different doses (0, 500, 1000, and 2000 mg/kg) administered orally to both male and female ICR mice for 14 d (five mice per group). After treatment, we evaluated general toxicity, survival rate, body weight changes, mortality, clinical signs, and necropsy findings in the experimental mice based on OECD guidelines. The results suggested that in vitro treatment with the evaluated extracts had no cytotoxic effect in HaCaT keratinocytes cells, whereas Sample-2 had a cytotoxic effect at 500 and 1000 ㎍/mL on HT22 hippocampal cells and RAW264.7 macrophages. Sample 3 was also cytotoxic at concentrations of 500 and 1000 ㎍/mL to RAW264.7 and BV2 microglial cells. However, the mice treated in vivo with the velvet extracts at doses of 500-2000 mg/kg BW showed no clinical signs, mortality, or necropsy findings, indicating that the LD50 is higher than this dosage. These findings indicate that there were no toxicological abnormalities connected with the deer velvet extract treatment in mice. However, further human and animal studies are needed before sufficient safety information is available to justify its use in humans.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.04a
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• pp.135-138
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• 2010

IMO adopt the revision of SOLAS convention on requirement systems for ECDIS and considered an ECDIS as the major system for E-Navigation strategy on marine transportation safety and environment protection. ENC(Electronic Navigational Chart) as base map of ECDIS is considered as a principal information infrastructure that is essential for navigation tasks. But ENCs are not easy to utilize because they are encoded according to ISO/IEC 8211 file format, and ENCs is required to utilize in parts of Marine GIS and various marine application because they are used for navigational purpose mainly. Meanwhile Google earth is satellite map that Google company service, is utilized in all kinds of industry generally providing local information including satellite image, map, topography, 3D building information, etc. In this paper, we developed KML conversion technology for ENC application. details of development contents consist of ENC loading module and KML conversion module. Also, we applied this conversion technology to Korea ENC and evaluated the results.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.12 no.4
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• pp.315-334
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• 2014

Wolsong Low- and Intermediate-level radioactive waste (LILW) disposal center has two different types of disposal facilities and interacts with the neighboring Wolsong nuclear power plant. These situations impose a high level of complexity which requires in-depth understanding of phenomena in the safety assessment of the disposal facility. In this context, multidimensional radionuclide transport model and hydraulic performance assessment model should be developed to identify more realistic performance of the complex system and reduce unnecessary conservatism in the conventional performance assessment models developed for the $1^{st}$ stage underground disposal. In addition, the advanced performance assessment model is required to calculate many cases to treat uncertainties or study parameter importance. To fulfill the requirements, this study introduces the development of two-dimensional integrated near-field performance assessment model combining near-field hydraulic performance assessment model and radionuclide transport model for the $2^{nd}$ stage near-surface disposal. The hydraulic and radionuclide transport behaviors were evaluated by PORFLOW and GoldSim. GoldSim radionuclide transport model was verified through benchmark calculations with PORFLOW radionuclide transport model. GoldSim model was shown to be computationally efficient and provided the better understanding of the radionuclide transport behavior than conventional model.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.25-31
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• 2020

In this study, for the safe use of a portable ultrasonic skin-beauty device, an android app was developed to show the irradiation locations of focused ultrasound to a user through augmented reality (AR) and enable stable self-surgery. The utility of the app was assessed through testing. While the user is making a facial treatment with the beauty device, the user's face and the ultrasonic irradiation location on the face are detected in real-time with a smart-phone camera. The irradiation location is then indicated on the face image and shown to the user so that excessive ultrasound is not irradiated to the same area during treatment. To this end, ML-Kit is used to detect the user's face landmarks in real-time, and they are compared with a reference face model to estimate the pose of the face, such as rotation and movement. After mounting a LED on the ultrasonic irradiation part of the device and operating the LED during irradiation, the LED light was searched to find the position of the ultrasonic irradiation on the smart-phone screen, and the irradiation position was registered and displayed on the face image based on the estimated face pose. Each task performed in the app was implemented through the thread and the timer, and all tasks were executed within 75 ms. The test results showed that the time taken to register and display 120 ultrasound irradiation positions was less than 25ms, and the display accuracy was within 20mm when the face did not rotate significantly.

• Journal of KIISE:Software and Applications
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• v.32 no.3
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• pp.215-226
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• 2005

Loop invariant code motion (LICM) optimization includes relatively heavy code analyses, thus being not readily applicable to Java Just-In-Time (JIT) compilation where the JIT compilation time is part of the whole running time. 'Classical' LICM optimization first analyzes the code and constructs both the def-use chains and the use-def chains. which are then used for performing code motions. This paper proposes a light-weight LICM algorithm, which requires only the def-use chains of loop invariant code (without use-def chains) by exploiting the fact that the Java virtual machine is based on a stack machine, hence generating code with simpler patterns. We also propose two techniques that allow more code motions than classical LICM techniques. First, unlike previous JIT techniques that uses LICM only in single-path loops for simplicity, we apply LICM to multi-path loops (natural loops) safely for partially redundant code. Secondly, we move loop-invariant, partially-redundant null pointer check code via predication support in Itanium. The proposed techniques were implemented in a JIT compiler for Itanium processor on ORP (Open Runtime Platform) Java virtual machine of Intel. On SPECjvrn98 benchmarks, the proposed technique increases the JIT compilation overhead by the geometric mean of 1.3％, yet it improves the total running time by the geometric mean of 2.2％.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.7C
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• pp.726-734
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• 2005

Traditional watermarking technologies are symmetric method which embedding and detection keys are the same. Although the symmetric watermarking method is easy to detect the watermark, this method has weakness against to malicious attacks remove or modify the watermark information when the symmetric key is disclosure. Recently, the asymmetric watermarking method that has different keys to embed and detect is watched by several researchers as a next generation watermarking technology. In this paper, hybrid asymmetric watermarking algorithm is proposed. This algorithm is composed of correlation detection method and critical criteria method. Each method can be individually used to detect watermark from a watermarked content. Hybrid asymmetric detection is complement between two methods, and more feasible than when each method is used respectively, Private key and public key are generated by secure linear transformation and specific matrix. As a result, we have proved the proposed algorithm is secured than symmetric watermarking algorithms. This algorithm can expand to multi bits embedding watermark system and is robust to JPEG and JPEG2000 compression.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.1 s.71
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• pp.93-103
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• 2006

It is absolutely essential that safety assessment of the containment buildings during service life because containment buildings are last barrier to protect radioactive substance due to the accidents. Therefore, this study describes an enhanced degenerated shell finite element(FE) which has been developed for nonlinear FE analysis of reinforced concrete(RC) containment buildings with elasto-plastic material model. For the purpose of the material nonlinear analysis, Drucker-Prager failure criteria is adapted in compression region and material parameters which determine the shape of the failure envelop are derived from biaxial stress tests. Reissner-Mindlin(RM) assumptions are adopted to develop the degenerated shell FE so that transverse shear deformation effects is considered. However, it is found that there are serious defects such as locking phenomena in RM degenerated shell FE since the stiffness matrix has been overestimated in some situations. Therefore, shell formulation is provided in this paper with emphasis on the terms related to the stiffness matrix based on assumed strain method. Finally, the performance of the present shell element to analysis RC containment buildings is tested and demonstrated with several numerical examples. From the numerical tests, the present results show a good agreement with experimental data or other numerical results.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2006.05a
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• pp.577-580
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• 2006

The rapidly growth of Internet is main factor that activates the Digital Contents market. However imprudent Digital Contents market could be shrunk by imprudent illegal copy and delivery. MPEG(Moving Picture Experts Group) proposed MPEG-21 Multimedia frameworks in order to solve these problem. IPMP is parts of MPEG-21 Multimedia Frameworks, when Digital Contents goes through production delivery consumption, which defines standard to keep the Digital Contents in safety. Currently IPMP defined by FCD(Final Committee Draft) level. Therefore development of system which applied to latest standard to protect and manage the Digital Contents is required. and the system consists of fourth organizations which means Metadata Production server, Tool server, License server, Consumption server. In this Paper, we made production server to parse REL(Rights Expression Language) document that has right information for content from license server, and create metadata based on MPEG-21 IPMP about the content that applied to watermark. then, after it do remuxing, transmit the protected data to consumption server.

• Journal of the Korean Geotechnical Society
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• v.38 no.11
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• pp.107-118
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• 2022

The social need for stable hydrogen storage technologies that respond to the increasing demand for hydrogen energy is increasing. Among them, underground hydrogen storage is recognized as the most economical and reasonable storage method because of its vast hydrogen storage capacity. In Korea, low-depth hydrogen storage using artificial protective structures is being considered. Further, establishing corresponding safety standards and ground stability evaluation is becoming essential. This study evaluated the hydro-mechanical behavior of the ground during a hydrogen gas leak from a low-depth underground hydrogen storage facility through the HM coupled analysis model. The predictive reliability of the simulation model was verified through benchmark experiments. A parameter study was performed using a metamodel to analyze the sensitivity of factors affecting the surface uplift caused by the upward infiltration of high-pressure hydrogen gas. Accordingly, it was confirmed that the elastic modulus of the ground was the largest. The simulation results are considered to be valuable primary data for evaluating the complex analysis of hydrogen gas explosions as well as hydrogen gas leaks in the future.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.43 no.6
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• pp.873-881
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• 2023

The evolution of civil engineering technology, exemplified by recent milestones like the completion of the Gangnam Global Business Center (GBC), has fostered the construction of expansive civil and architectural structures both above and below the earth's surface. This surge in construction necessitates a commensurate advancement in research and technology pertaining to safety protocols applicable to these vast edifices. Such protocols encompass a spectrum of concerns, ranging from the preemptive mitigation of accidents to the effective management of exigencies such as fires. As the trajectory of construction endeavors continues unabated, encompassing both subterranean and elevated domains, a concomitant imperative emerges to refine the methodologies underpinning precise indoor positioning. To address this need, an innovative web-based simulator has been devised to emulate indoor positioning scenarios for rigorous testing. This research further entails the development of an indoor positioning data Application Programming Interface (API) fortified by Geographic Information System (GIS) spatial operation techniques. This API is anchored in the construction of intricate test data, centered on the spatial layout of building 13 at the Electronics and Telecommunications Research Institute (ETRI). Consequently, the study renders feasible the expeditious provisioning of diverse signal-based and image-based spatial information, pivotal for enhancing the navigational acumen of mobile devices. Path delineation, cellular signal mapping, landmark identification, and ancillary navigational aids are among the manifold datasets promptly furnished by the indoor positioning data API. In summation, this study engenders a crucial leap towards the fortification of safety protocols and navigational precision within the expansive confines of modern architectural wonders.