• The Journal of the Korean bone and joint tumor society
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• v.14 no.1
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• pp.44-50
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• 2008

Purpose: To evaluate usefulness in diagnosing primary malignant lesion of metastatic bone tumor using $^{18}F$ FDG PET/CT. Material & Methods: Retrospective analysis was executed on 5,452 patients who were taken with $^{18}F$ FDG PET/CT between December 2003 and December 2007. 180 patients who had not any history of malignancy and complained musculoskeletal pain and had ill-defined osteolytic lesion in plain X-ray, were included. 96 male and 84 female were enrolled and mean age was 59.1 year old (22~90). We analyzed diagnostic accuracy, age and sex distribution of primary malignant lesion, location of metastatic lesion. Results: We could confirmed primary malignant lesion in 152 cases (84.4%). Most common malignant primary lesion was lung (28.3%), breast (18.9%) and gastrointestinal system (16.7%) and spine was the most common metastatic location of primary malignant lesion. Conclusion: $^{18}F$ FDG PET/CT is a effective molecular imaging detecting primary malignant lesion in patients having metastatic bone lesion without history of malignancy.

• Investigative Magnetic Resonance Imaging
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• v.14 no.2
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• pp.145-150
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• 2010

We report the case of a 16-year-old boy with a solid pancreatic mass which proved to be a nonfunctioning, malignant pancreatic neuroendocrine tumor (PNET). In pediatric patients, malignant pancreatic tumors are rare, especially malignant PNET. When dynamic contrast enhanced MRI showed a well enhancing solid pancreatic tumor on arterial and delayed phases and combined with malignant features, such as vascular invasion, invasion of adjascent organs, and lymphadenopathy, we should include malignant pancreatic neuroendocrine tumor in the differential diagnosis of childhood pancreatic tumors.

• Proceedings of the Acoustical Society of Korea Conference
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• 1998.06e
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• pp.399-402
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• 1998

본 논문에서는 환자의 음성을 정상, 양성종양, 악성종양으로 분류하는 실험을 켑스트럼 파라미터를 통한 음원분리와 신경회로망을 이용하여 수행하고 그 결과를 보고한다. 기존의 장애음성 데이터베이스에는 정상음성과 양성종양의 경우만 수록되어 있었고 외국의 환자들을 대상으로 한 경우만 있었기 때문에 국내의 환자들에게 직접 적용할 경우 어떠한 결과가 나올지 예측하기가 어려웠다. 최근 부산대학교 이비인후과팀에서 수집한 국내의 정상, 양성, 악성종양의 경우에 대한 데이터베이스를 분석하고 신경회로망에 의해 분류함으로써 사람의 음성신호만에 의한 후두질환이 식별이 가능하였다. 본 실험에서는 식별 파라미터로 음성신호의 선형예측오차신호에 관한 켑스트럼으로부터 음원비인 HNRR을 구하여 Jitter, Shimmer와 함께 사용하였다. 신경회로망은 입, 출력 층과 한 개의 은닉층을 갖는 다층신경망을 이용하였으며, 식별은 두단계로 나누어 정상과 비정상을 분류한 후 다시 비정상을 양성과 악성으로 분류하였다[1].

• Journal of the Korean Society of Radiology
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• v.81 no.5
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• pp.1109-1120
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• 2020

Pleural masses may be caused by various conditions, including benign and malignant neoplasms and non-neoplastic tumorlike conditions. Primary pleural neoplasms include solitary fibrous tumor, malignant mesothelioma, and primary pleural non-Hodgkin's lymphoma. Metastatic disease is the most common neoplasm of the pleura and may uncommonly occur in patients with hematologic malignancy, including lymphoma, leukemia, and multiple myeloma. Pleural effusion is usually associated with pleural malignancy. Rarely, pleural malignancy may arise from chronic empyema, and the most common cell type is non-Hodgkin's lymphoma (pyothorax-associated lymphoma). Non-neoplastic pleural masses may be observed in several benign conditions, including tuberculosis, pleural plaques caused by asbestos exposure, and pleural loose body. Herein, we present a review of benign and malignant pleural neoplasms and tumorlike conditions with illustrations of their computed tomographic images.

• Journal of the Korean Society of Radiology
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• v.82 no.2
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• pp.493-497
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• 2021

A malignant rhabdoid tumor is an aggressive tumor that occurs mainly in the kidney of infants and children. When it occurs in extrarenal sites, it is referred to as an extrarenal malignant rhabdoid tumor. Although a few cases of malignant rhabdoid tumor occuring in the central nervous system, liver, brain, skin, and soft tissue have been reported, it is rarely observed in the stomach. We report the imaging findings of a malignant rhabdoid tumor of the stomach that mimicked a gastric lymphoma in a patient who presented with melena.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1996.04a
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• pp.85-85
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• 1996

경부기도의 종양은 편평상피암과 함께 이비인후과의에게 있어서 호흡곤란 환자의 감별진단을 위해 매우 중요한 임상적 의미를 갖는다. 종양은 암종에 의한 사망률의 0.1%이하를 차지하는 드문 질환이며 선양낭성암종은 기도의 원발성 종양중 두 번째로 많은 질환이다. 갑상선종양의 기도의 직접적인 침범이 흔히 발견되는 상태이며, 그다음으로 편평상피암, 선양낭성암종이 기도의 원발성 종양으로 흔한 질환이다. 갑상선의 악성종양이 기도의 벽이나 내강을 침입하는 것과 마찬가지로, 기도의 원발성 악성종양도 흔히 갑상선을 침범하여 갑상선의 종괴처럼 발현할 수 있다. 본 연구는 이와 같이 갑상선의 악성종양과 유사한 임상경과를 보이는 기도의 선양낭성암종의 향후 감별진단을 위해 4명의 조직학적으로 증명된 갑상선을 침범하는 기도의 선양낭성암종환자의 임상기록과 전산화 단층촬영소견을 후향적으로 관찰하였다. 전산화 단층촬영에서 이들은 기도에 넓은 기저부를 가지고 갑상선을 밀고있는 균일한 음영의 일반적으로 부드러운 경계를 가지는 종괴로 보였으며, 횡단면과 두정면에서 모두 기도 벽의 비후소견을 보였다. 이러한 소견은 기도의 원발성 선양낭성암종의 감별에 도움이 될 것으로 생각된다.

• Tuberculosis and Respiratory Diseases
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• v.47 no.3
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• pp.331-338
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• 1999

Background: Nearly 10% of cancer patients will develop a second primary cancer within ten years after surgical removal of the primary tumor. The detection of risk factors for developing multiple primary tumors would be important This study was conducted to evaluate the clinical characteristics and abnormal p53 expression of lung cancer associated with multiple primary cancer(MPC). Method: Clinical characteristics and abnormal p53 expression were compared between 20 cases of lung cancer(NSCLC ; 16 cases, SCLC ; 4 cases) associated with MPC and 26 cases of primary non-small cell lung cancer. Result: MPC associated with lung cancer was gastric cancer(8), lung cancer(2), esophageal cancer(2), colon cancer(2), laryngeal cancer(1), bladder cancer(1), small bowel cancer(l), adrenal cancer(1), hepatocellular carcinoma(1), and breast cancer (1) in order. The clinical stage of primary NSCLC was relatively advanced, but NSCLC associated with MPC was even distribution at each stage. The detected incidences of abnormal p53 expressions were 62.5% in NSCLC associated with MPC and 76.9% in primary NSCLC(p>0.05). Conclusion: There was no difference in abnormal p53 expression between non-small cell carcinoma associated with multiple primary cancer and primary non-small cell carcinoma.

• Journal of Yeungnam Medical Science
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• v.13 no.1
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• pp.78-85
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• 1996

The authors reviewed 95 cases(46 men and 49 women) of the orbital tumors diagnosed histopathologically at the Department of Ophthalmology, Yeungnam University Hospital from March 1984 through August 1994. Seventy-five cases of benign tumors were found evenly in all decades, but twenty cases of malignant tumors were noticed more frequently in 1st, 6th, and 7th decades. The frequency of benign orbital tumors was in this order; dermolipoma(21%, 20 cases), dermoid cyst(11.6%, 11 cases), mucocele(8.4%, 8 cases), lipoma(7.4%, 7 cases) and pleomorphic adenoma(5.3%, 5 cases). Of malignant orbital tumors, the frequency was in this order; retinoblastoma(3 cases), malignant melanoma(2 cases), sebaceous carcinoma(2 cases), and maxillary sinus carcinoma(2 cases). Malignant orbital tumors of 8 expired patients were revealed as secondary or metastatic tumors.

• Korean Journal of Head & Neck Oncology
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• v.10 no.1
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• pp.25-30
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• 1994

Minor salivary gland tumors vary in their primary sites, histopathology and bilogical behavior. Therefore various factors are considered in selecting the treatment modality and predicting the prognosis. The prognosis of milignant tumors of minor salivary glands are worse than that of such lesions of major salivary glands. Authors experienced 26 cases of minor salivary gland tumors(10 benign tumors and 16 malignant tumors) during the past 7 years and analyzed their clinical characteristics. 1) The palate was the most common site of origin of minor salivary gland tumors (38.5%). 2) The most common benign tumor was pleomorphic adenoma and majority of them occur red in the palate(60.0%) and the remaining occured in the nasal cavity or the paranasal sinuses (30.0%), and the lip ( 10.0%). 3) In the case of malignant tumors the most frequent sites were the nasal cavity or the paranasal sinuses (31.3%) with the following histopathologic frequencies: adenoid cystic carcinoma(56.3%), malignant pleomorphic adenoma(12.5%), mucoepidermoid carcinoma(12.5%), polymorphic adenocarcinoma (12.5%), epthelial-myoepithelial carcinoma (6.25%). 4) Minor salivary gland tumors have high probability of malignancy and tumor extension is important to their treatment.

• The Journal of the Korean bone and joint tumor society
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• v.14 no.2
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• pp.119-124
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• 2008

Purpose: To present our experience with soft tissue reconstruction using anterolateral thigh free flap after resection of soft tissue sarcoma. Materials and Methods: Between January of 2003 and June of 2007, we treated 7 patients with soft tissue reconstruction using anterolateral thigh free flap after wide resection for soft tissue sarcoma. We retrospectively analyzed type and size of tumors, resection margin, size of defect after resection, time of operation, flap survival and complication. Results: The type of sarcoma was 3 synovial sarcoma, 2 malignant fibrous histiocytoma, 1 leimyosarcoma and 1 fibrosarcoma. The size of tumor varied from $3{\times}5\;cm$ to $7{\times}8\;cm$. The resection margins of tumors were negative in all cases. The size of soft tissue defect after resection varied from $6{\times}8\;cm$ to $15{\times}10\;cm$. The mean time of operation was 3.6 hours. All flaps were survived. Conclusion: Anterolateral thigh free flap appear to be ideal for reconstruction after wide resection of soft tissue sarcoma.