• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.15 no.4
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• pp.321-332
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• 2017

In order to build a general model of a high-throughput uranium electrorefining process according to the electrode configuration, numerical analysis was conducted using the COMSOL Multiphysics V5.3 electrodeposition module with Ordinary Differential Equation (ODE) interfaces. The generated model was validated by comparing a current density-potential curve according to the distance between the anode and cathode and the electrode array, using a lab-scale (1kg U/day) multi-electrode electrorefiner made by the Korea Atomic Energy Research Institute (KAERI). The operating temperature was $500^{\circ}C$ and LiCl-KCl eutectic with 3.5wt% $UCl_3$ was used for molten salt. The efficiency of the uranium electrorefining apparatus was improved by lowering the cell potential as the distance between the electrodes decreased and the anode/cathode area ratio increased. This approach will be useful for constructing database for safety design of high throughput spent nuclear fuel electrorefiners.

• Korean Chemical Engineering Research
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• v.54 no.3
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• pp.380-386
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• 2016

In this study, we described a paper-based neuraminidase assay sensor (PNAS) which can be applied to detect the infection by influenza viruses. The PNAS was designed and manufactured to quantitatively identify the levels of neuraminidase in the sample, which is based on colorimetric analysis using the X-Neu5Ac substrate. The limit of detection of the PNAS was determined as 0.004 U/mL of neuraminidase. According to the amount of neuraminidase in human serum, the PNAS could monitor the enzyme activity with a good linearity ($R^2$ > 0.99). In addition, the initial performance of the PNAS has been maintained up to 70 days in the $4^{\circ}C$. Finally, we demonstrated whether the Michaelis-Menten kinetics is applied to the PNAS, which can show the reliability of the enzyme reactions. The kinetic studies indicated that the PNAS provides the good condition for enzyme reactions ($K_m=8.327{\times}10^{-3}M$), but they were performed on paper chip nonetheless. The paper-based neuraminidase assay sensor may be useful in a wide range of rapid and safe detection of influenza virus.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.2
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• pp.87-94
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• 2017

Because the cavitation flow driven by an underwater propeller corrodes the materials around it and generates a high level of noise, it has become an important topic in engineering research. In this study, computational fluid dynamics techniques are applied to simulate cavitation flow, and the noise in the flow is predicted by applying the acoustic analogy to the predicted flow. The predicted results are compared with measurement results and other predictions in terms of surface pressure distribution and the temporal variation in liquid volume fraction. The predicted results are found to be in good agreement with the measured results. The source of the noise attributed to the time rate of change in the liquid volume fraction around the hydrofoil is modeled as a monopole source, and the source of the noise due to unsteady pressure perturbations on the hydrofoil surface is modeled as a dipole source. Then the predicted noise results are analyzed in terms of directivity and SPL spectrum. The noise caused by unsteady pressure perturbations was dominant in the entire frequency range considered in the study.

• The Korean Journal of Nuclear Medicine
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• v.36 no.2
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• pp.133-139
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• 2002

Purpose: Scintillation Proximity Assay (SPA) does not require the physical separation of receptor bound form from free form. SPA was applied to the study of interaction of human chorionic gonadotropin (hCG) and $anti-{\alpha}$ hCG in serum. Materials and methods: $Anti-{\alpha}$ hCG was biotinylated for the binding to streptavidin. The assay was based on the simple competitive binding method between $[^{125}I]hCG$ and the hCG in sample serum, with $anti-{\alpha}$ hCG-coated beads. Aliquots of biotinylated $anti-{\alpha}$ hCG were dispensed into scintillation vials containing $100{\mu}{\ell}\;[^125}I]hCG\;and\;200{\mu}{\ell}$ of either a standard concentration of hCG for preparation of standard curve or unknown sample, and incubated for 20 min. at room temperature. Then $20{\mu}{\ell}$ streptavidin-coated beads were added to vials, and finally incubated for 10 min at room temperature. Values for unknown samples were then calculated from the standard curve. Results: Optimal background counts were certificated using varied radioactivity of radionuclides. Appropriate standard curve was obtained from SPA method successively, and the concentration of hCG from unknown serum was determined by standard curve. The result from SPA assay was similar to that of RIA. Conclusion: This observation confirms that SPA method could be useful for clinical diagnosis.

• Journal of Environmental Science International
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• v.11 no.7
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• pp.637-650
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• 2002

This study presents an investigation of the changes of the currents in Kwangyang Bay due to the construction of harbor, reclamation and coastal developments. Currents were simulated by the numerical experiments with a diagnostic multi-level model and using the seasonal oceanographic data of temperature, salinity and ocean current. The values of kinetic and potential energies for the currents were calculated in cases of three topographical changes; before coastal developments, the existing state and after completion of the development project in Kwangyang Bay. The changes of currents due to the coastal developments are as follow; Kinetic energies of tide induced residual currents and wind driven currents decreased by 35~40 percent and 5 percent respectively, however those of density currents increased by 10 percent since the decrease of the coastal areas. Kinetic energy of residual currents including tide induced residual currents, density currents and wind driven currents reduced by 10 percent compared with before the coastal developments. Decrease of current velocity was greatest in summer. Therefore, in summer it was assumed that the Kwangyang Bay is more easily polluted by stratification and decrease of residual current than before the coastal developments carried out.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.4
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• pp.129-134
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• 2018

Recently, the artificial neural network (ANN) model is a promising technique in the prediction, numerical control, robot control and pattern recognition. We predicted the outside temperature of greenhouse using ANN and utilized the model in greenhouse control. The performance of ANN model was evaluated and compared with multiple regression model(MRM) and support vector machine (SVM) model. The 10-fold cross validation was used as the evaluation method. In order to improve the prediction performance, the data reduction was performed by correlation analysis and new factor were extracted from measured data to improve the reliability of training data. The backpropagation algorithm was used for constructing ANN, multiple regression model was constructed by M5 method. And SVM model was constructed by epsilon-SVM method. As the result showed that the RMSE (Root Mean Squared Error) value of ANN, MRM and SVM were 0.9256, 1.8503 and 7.5521 respectively. In addition, by applying the prediction model to greenhouse heating load calculation, it can increase the income by reducing the energy cost in the greenhouse. The heating load of the experimented greenhouse was 3326.4kcal/h and the fuel consumption was estimated to be 453.8L as the total heating time is $10000^{\circ}C/h$. Therefore, data mining technology of ANN can be applied to various agricultural fields such as precise greenhouse control, cultivation techniques, and harvest prediction, thereby contributing to the development of smart agriculture.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.1
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• pp.37-44
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• 2019

A bond-based peridynamic model has been reported dynamic fracture characteristic of brittle materials through a simple constitutive model. In the model, each bond is assumed to be a simple spring operating independently. As a result, this simple bond interaction modeling restricts the material behavior having a fixed Poisson's ratio of 1/4 and not being capable of expressing shear deformation. We consider a state-based peridynamics as a generalized peridynamic model. Constitutive models in the state-based peridynamics are corresponding to those in continuum theory. In state-based peridynamics, thus, the response of a material particle depends collectively on deformation of all bonds connected to other particles. So, a state-based peridynamic theory can represent the volume and shear changes of the material. In this paper, the perfect plasticity is considered to express plastic deformation of material by the state-based peridynamic constitutive model with perfect plastic flow rule. The elastic-plastic behavior of the material is verified through the stress-strain curves of the flat plate example. Furthermore, we simulate the high-speed impact on 3D granite model with a nonlocal contact modeling. It is observed that the damage patterns obtained by peridynamics are similar to experimental observations.

• Journal of Korea Water Resources Association
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• v.55 no.5
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• pp.383-392
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• 2022

The restoration of the Nakdong River estuary is one of the most important projects of the Ministry of Environment, Republic of Korea. A real-scale experiment of gate operation was executed from 2019 to 2020, and a pilot operation was performed in 2021. The gate of Nakdong River Estuary Barrier (NEB) is supposed to be continuously opened based on the experiment results. Many critical decisions should be made immediately during the experiment based on the real-time measured data and numerical analysis considering the seawater inflows. The decision-making sequence was made systematically with the accurate estimation of seawater inflow. The estimation of seawater inflow is the main research objective and the equations of seawater inflow were developed, reflecting the structural characteristics of NEB. The inflow equations were developed in two forms, overflow and underflow. ADCP (Acoustic Doppler Current Profiler) was used to measure seawater inflow, check the accuracy of the developed equations, and derive the flow coefficient. The comparison error of the developed equations was about 3% compared to the measured data.

• Explosives and Blasting
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• v.40 no.3
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• pp.19-32
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• 2022

Hydrogen is a fuel having the highest energy compared with other common fuels. This means hydrogen is a clean energy source for the future. However, using hydrogen as a fuel has implication regarding carrier and storage issues, as hydrogen is highly inflammable and unstable gas susceptible to explosion. Explosions resulting from hydrogen-air mixtures have already been encountered and well documented in research experiments. However, there are still large gaps in this research field as the use of numerical tools and field experiments are required to fully understand the safety measures necessary to prevent hydrogen explosions. The purpose of this present study is to develop and simulate 3D numerical modelling of an existing hydrogen gas station in Jeonju by using handheld LiDAR and Ansys AUTODYN, as well as the processing of point cloud scans and use of cloud dataset to develop FEM 3D meshed model for the numerical simulation to predict peak-over pressures. The results show that the Lidar scanning technique combined with the ANSYS AUTODYN can help to determine the safety distance and as well as construct, simulate and predict the peak over-pressures for hydrogen refueling station explosions.

• Journal of Chest Surgery
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• v.38 no.1 s.246
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• pp.13-22
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• 2005

It has been known that pulsatile flow is physiologic and more favorable to tissue perfusion than nonpulsatile flow. The purpose of this study is to directly compare the effect of pulsatile versus nonpulsatile blood flow to renal tissue perfusion in extracorporeal circulation by using a tissue perfusion measurement system. Material and Method: Total cardiopulmonary bypass circuit was constructed to twelve Yorkshire swines, weighing 20$\~ $30 kg. Animals were randomly assigned to group 1 (n=6, non pulsatile centrifugal pump) or group 2 (n=6, pulsatile T-PLS pump). A probe of the tissue perfusion measurement system $(QFlow^{TM}-500)$ was inserted into the renal pa­renchymal tissue. Extracorporeal circulation was maintained for an hour at a pump flow of 2 L/min after aortic cross-clamping. Tissue perfusion flow of the kidney was measured at baseline (before bypass) and every 10 minutes after bypass. Serologic parameters were collected at baseline and 60 minutes after bypass. Result: Baseline parameters were not different between the groups. Renal tissue perfusion flow was substantially higher in the pulsatile group throughout the bypass (ranged 48.5$\~$ 64 in group 1 vs. 65.8$\~$88.3 mL/min/100 g in group 2, p=0.026$\~$ 0.45) The difference was significant at 30 minutes bypass $(47.5{\pm}18.3\;in\;group\;1\;vs.\;83.4{\pm}28.5$ mL/min/100 g in group 2, p=0.026). Serologic parameters including plasma free hemoglobin, blood urea nitrogen, and creatinine showed no differences between the groups at 60 minutes after bypass (p=NS). Conclusion: Pulsatile flow is more beneficial to tissue perfusion of the kidney in short-term extracorporeal circulation. Further study is suggested to observe the effects to other vital organs or long-term significance.