• The Journal of the Korea Contents Association
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• v.9 no.1
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• pp.348-358
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• 2009

Diffuse axonal injury(DAI) is a common form of traumatic brain injury and thought to be a major contributor to cognitive dysfunction. Physical activity has been shown to beneficial effects on physical health and influences in hippocampus which is an important location for memory and learning. The purpose of this study was to investigate the effect of motor training on motor performance and axonal regeneration in hippocampus through the immunoreactivity of GAP-43 after diffuse axonal injury in the rats. The experimental groups were applied motor training(beam-walking, rotarod, and Morris water maze) but control groups were not. The time performing the motor tasks and GAP-43 immunohistochemistry were used for the result of axonal recovery. There were meaningful differences between experimental groups and control groups on motor performance and GAP-43 immunohistochemistry. The control groups showed increasing tendency with the lapse of time, but experimental groups showed higher. Therefore, Motor training after DAI improve motor outcomes which are associated with dynamically altered immunoreactivity of GAP-43 in axonal injury regions, particularly hippocampus, and that is related with axonal regeneration.

• Korean Journal of Psychosomatic Medicine
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• v.4 no.1
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• pp.146-154
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• 1996

The impact of stress on immune function is known to be associated with the interactions among the central nervous system(CNS), neuroendocrine system, and immune system. The main pathways between stress and immune system are wiring of lymphoid organs and neuroendocrine system. Immune system also produces neuropeptides, which modulate immune system. Mediators of psychosocial influences on immune function are found to be peptides released by the pituitry, hormones, md autonomic nervous system. Hypothalamus integrates endocrine, neural and immune systems. Particularly, paraventricular nucleus appears to play a central role in this integration. On the other hand, endocrine system receives feedback from the immune system. The major regulatory pathways which pituitary modulates include the hypothalamic-pituitary-adrenal-thymic(HPAT) axis, hypothalamic-pituitary-gonadal-thymic(HPGT) axis, pineal-hypothalamic-pituitary(PHP) axis. Bidirectional pathways such as feedforward and feedback pathways are suggested in the interaction between stress and immune system. It suggests that psychosocial inputs affect immune function, but also that immunological inputs affect psychosocial function. Thus, prospective studies for elucidating the relationship between stress and immune function should incorporate measures of immune function as well as measures of endocrine, autonomic, and brain activities at the same time.

• Physical Therapy Korea
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• v.8 no.4
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• pp.17-29
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• 2001

발목에 대한 유착성 테이핑의 적용은 물리치료 분야와 운동 트레이닝 분야에서의 일반적인 치료 접근 방법이라 할 수 있다. 즉 발목 염좌 같은 손상을 예방하기 위한 방법과 재활의 부가적인 치료 형태로 이용될 수 있는 것이다. 본 연구는 발목의 테이핑과 트레드밀에서의 30분간 보행이 수직 착지 동작 동안 하지의 운동 역학적 요소들에 어떠한 영향을 주는지 알아보기 위해 시행되었다. 14명의 신체 건강한 대상자들 (남:10, 여:4)이 본 연구에 참여하였다. 한발로 서있는 동안 40 cm의 높이로 뛰게 하였다. 가자미근, 전경골근, 안쪽넓은근, 넙다리 두갈래근에 근전도 전극이 부착되었다. 테이핑된 신체 부위로 착지하는 동안 근전도와 힘판(force plate) 자료가 500 Hz의 주파수로 수집되었다. 대상자들의 우세쪽 하지 발목에 테이핑을 하였고, 대상자는 한발로 뛰어 내리는 동작을 반복하였다. 트레드밀에서 30분 동안 발목에 테이핑을 한 채로 보행하였고 이후 한발로 뛰어 내리는 동작을 반복하여 수행하였다. 테이핑을 적용한 상태와 테이핑한 채로 30분 동안 트레드밀에서 걷기 운동을 한 조건에서 수직 지면 반발력의 통계학적으로 유의미한 증가가 있었다. 착지 동안에 네 가지 상황에서의 최대 내측 가속도의 유의한 차이가 있었고, 그 차이는 테이핑 전과 테이핑을 한 채로의 운동 조건에서 유의한 차이가 있었다. 테이핑한 상태에서 가자미근은 접촉되는 착지 순간부터 최대 수직 지면 반발력이 나타나는 동안의 평균 근전도의 수치에 있어서 유의한 감소가 있었다. 반면에 다른 근육들에서는 아무런 변화를 보이지 않았다. 비록 발목 테이핑이 발목 손상의 위험을 줄이는데 효과적이라고 일반적으로 인식되고 있으나 이번 실험의 결과는 30분 동안의 트레드밀에서의 보행 후 테이핑은 발목의 움직임을 제한하는 효과는 있지만 한편으로는 가자미근의 활동을 감소시키는 것을 보여주었다. 따라서 이 연구의 결과는 테이핑을 하면 점프와 착지로 이어지는 동작 중에 발목관절 손상 위험을 증가시킬 가능성이 있음을 보여주었다.

• Journal of the Korea Convergence Society
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• v.9 no.10
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• pp.549-559
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• 2018

The purpose of this study is to examine the prevalence of depression in Korean middle-aged adults and to identify the gender difference in factors associated with the severity of depression. The data of 2,241 individuals who participated in the Sixth Korea National Health and Nutrition Examination Survey in 2014 were used. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9), and multivariate ordinal logistic regression analysis was performed. The prevalence rate of moderate to severe depression ($PHQ-9{\geq}10$) was identified at 5.2% (men 3.3%, women 7.0%). The factors associated with the severity of depression in men were younger age, living in metropolitan, unemployed, lower body mass index, and heavily drinking. On the other hand, women were affected by having no spouse, lower income, limited physical activity, and sleeping shorter hours.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.61-65
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• 2016

Currently, a variety of Information and Communication Technology(ICT) is being broadly utilized for mental health. Especially, mobile application is one of the effective ICT, and several applications have been developed after the spread of smartphones. The mobile-based mental health has several strengths, such as better treatment accessibility and easier check-ups of symptoms or daily activities by real-time monitoring. Better follow-ups of treatment course, more customized feedback and better transportability enable patients to be more adherent. However, there are some limitations of mobile technology about the mental health, such as technical troubles of electric errors, data safety problems and personal information extrusion. Therefore, full considerations should be given during the development and provision of the technology. Most of all, mental health specialists should actively participate in the development process by incorporation of evidence-based experiences and assurance of good clinical qualities.

• Journal of Applied Biological Chemistry
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• v.62 no.3
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• pp.305-313
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• 2019

Men's climactic syndrome, andropause, or testosterone deficit syndrome, is one of the new problems with the health of older men in the age of aging. This phenomenon is a natural phenomenon occurring in men as they age, clinically characterized by a decrease in blood testosterone levels and a marked decrease in physical and mental activity. The purpose of this study was to investigate the effect of hydrothermal extract of Taraxacum coreanum by comparing the levels of nitric oxide (NO) in the cavernosum and the levels of male hormone in the blood. Taraxacum coreanum extract increased NO production in vitro and in vivo in a dose-dependent manner. Levels of dihydrotestosterone and 17-hydroxyysteroid dehydrogenases, as well as levels of neurogenic nitric oxide synthase and cGMP, increased significantly in elderly rats (22 weeks) after 4 weeks of daily intake of Taraxacum coreanum extract. However, prostaglandin $E_2$, testosterone, and sexually-hormone-binding globulin levels were not different among all groups. Furthermore, total sperm and motile sperm counts were also no significant difference. Overall, these results suggest the possibility of Taraxacum coreanum extract as a safe and effective natural substance for enhancing NO, cGMP and free testosterone.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.46-54
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• 2022

This is a study using data from the 8th National Health and Nutrition Examination Survey to identify the factors that affect the handgrip strength and health status in the elderly. Bivariate logistic regression analysis was performed on 1,470 subjects. As a result of this study, the decrease in grip strength was significantly lower for males, 70-74 or 65-69 years of age, and those who thought their subjective health status was normal or good. The decrease in grip strength was significantly higher when the education level was less than elementary school or middle school, and when the sleeping time was more than 8 hours. Considering the variables affecting hand grip strength, it can be used as basic data when establishing health policies for the elderly or health promotion policies to improve grip strength as a primary prevention activity.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.2
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• pp.78-82
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• 2014

Purpose The physiological and biochemical responses of healthy men and women to life stress were measured in order to investigate the correlation between these two responses under the normal situation. Materials and Methods The population of the research is some randomly chosen health college students located in Daejeon City during the period from August to September 2014, and the sample of 94 students. Heart rate variability (HRV), blood pressure (BP) were selected as physiological stress indices and serum cortisol level was used as a biochemical stress biomaker. The data which is collected used SPSS19.0 programs and frequency and percentage and T-test, correlation. Results Male showed the significant higher value of serum cortisol level (p<0.05), BP (p<0.05), and LF/HF ratio of HRV (p<0.05) than female. The difference of BP between correlated significantly with serum cortisol level (p<0.05). The LF/HF ratio of HRV also correlated significantly with serum cortisol level (p<0.05) Conclusion We suggest that LF/HF ratio of HRV and BP may be good indices for the assessment of life stress.

• 한국노년학
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• v.27 no.2
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• pp.371-392
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• 2007

Marital status has drawn much attention as previous studies have been pointed it out as a key factor of health. Nonetheless, systematic studies on elderly marital status and health have been quite limited, for most researches have neglected the varying effects of marital status on health over the lifespan and mainly focused on midlife. This study, using nationwide survey on elderly population, attempts to discover the health differentials between widowed and married elderly and explain the differences though the structure and function of their social network. The results reveal that the magnitudes of marital status effects were differed by dimensions of health. The widowed were more likely to be unhappy than married, even after controlling the socio-demographic characteristics. In physical health, however, the health differences between widowed and married were less noticeable or disappeared, as sex, age and other structure factors were considered. Furthermore, the strength of social network factors affecting the physical and mental health of elderly turned out to be different between married and widowed: widowed were more likely than married to be affected by the contact with children and less likely to be affected by contact with friends/relatives. Such results had both positive and negative impact on physical and mental health of widowed. This may imply the difference in pathways of regulating health among the married and widowed elderly.

• Journal of the Korean Society of Radiology
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• v.18 no.2
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• pp.127-133
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• 2024

The elbow joint is made up of three different bones. X-rays or other radiological exams are commonly used to diagnose elbow injuries or disorders caused by physical activity and external forces. Previous research on the elbow joint reported a new examination method that meets the imaging evaluation criteria in the tilt position by Z-axis elevation of the forearm. Therefore, this study aims to design an optimized instrument and develop an aid applicable to other upper extremity exams. After completing the 2D drawing and 3D modeling design, the final design divided into four parts was fabricated with a 3D printer using ABS plastic and assembled. The developed examination aid consists of a four-stage Z-axis elevation tilt angle function (0°, 5°, 10°, and 15°) and can rotate and fixate 360° in 1-degree increments. It was designed to withstand a maximum equivalent stress of 56.107 Pa and a displacement of 1.6548e-5 mm through structural analysis to address loading issues caused by cumulative frequency of use and physical utilization. In addition to X-ray exams of the elbow joint, the developed aid can be used for shoulder function tests by rotating the humerus and also be applied to MRI and CT exams as it is made of non-metallic materials. It will contribute to the accuracy and efficiency of medical imaging diagnosis through clinical applications of various devices and medical imaging exams in the future.