• Title/Summary/Keyword: 신장암

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Application of Radiofrequency Ablation to Thyroid Cancer: Past, Present, and Future (갑상선암에 대한 고주파 절제 적용의 과거, 현재, 그리고 미래)

  • Ji-hoon Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.5
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    • pp.999-1008
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    • 2023
  • Thyroid cancer, characterized by high incidence rates, good prognosis, and frequent recurrence, is typically treated surgically. However, since the early 2000s, radiofrequency ablation, which is commonly utilized in liver, lung, and kidney cancers, is being performed for management of primary and recurrent thyroid cancers. Many studies have focused on inoperable cases of low-risk papillary microcarcinoma (≤ 1 cm) and some have investigated its role in larger lesions (up to 4 cm). Overall, these studies have reported positive results. Radiofrequency ablation for recurrent cancer has primarily been performed for locally recurrent cervical cancer, and this therapeutic approach has been attempted for treatment of distant metastases in lungs and bones, with encouraging outcomes. A growing global trend, particularly in South Korea, the United States, and Europe supports radiofrequency ablation for thyroid cancer. However, this therapy is currently not recognized as a treatment option recommended by universally accepted clinical guidelines such as those established by the National Comprehensive Cancer Network. Based on past efforts and future research, radiofrequency ablation is expected to play a key role in thyroid cancer treatment in the near future.

A convergence study about Influences of hematopoietic stem cell transplantation on children growth (소아암 환아의 조혈모세포이식 후 성장에 관한 융합 연구)

  • Lim, Su-Jin
    • Journal of the Korea Convergence Society
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    • v.8 no.4
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    • pp.49-57
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    • 2017
  • This is a convergence study about influences of hematopoietic stem cell transplantation on children growth. For this explanatory survey research, data were collected with medical record of 112 children with malignant and hematological diseases received HSCT from February to March, 2009. To analyze the growth after HSCT, mixed-effects model was used. The mean SDS of height and weight were negative values in HSCT. The mean value of SDS were significantly lower in autologous HSCT group by height(p=0.0008) and weight(p= 0.0012). Significant factors on changes of SDS of height growth were age at HSCT(p=0.0251), autologous HSCT(p=0.0020) and total dose of steroid in allogeneic HSCT (p=0.0403) and age at HSCT(p=0.0042), autologous HSCT(p=0.0035), and duration of TPN(p=0.0159) for weight growth. According to the results, we must learn to recognize the predicting growth impairment after HSCT in children. regarding nursing interventions should be conducted in the care of these children.

한국산 인삼, 장뇌삼 및 중국산 장뇌삼의 항암 활성에 관한 연구

  • Hwang, Yu-Jin;Yang, Hui-Jin;Jeong, Sun-Hui;Lee, Su-Won
    • Proceedings of the Korean Society for Food Science of Animal Resources Conference
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    • 2006.05a
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    • pp.306-308
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    • 2006
  • 한국산 인삼과 장뇌삼, 중국산 장뇌삼 용매별 추출물을 처리하여 세포 독성을 비교 관찰한 결과, 모든 암세포주에서 농도 의존적인 세포 독성을 나타내었다. 자궁암 세포주인 HeLa에서는 hexane과 butanol 추출물이, 결장암 세포주인 HT29에서는 butanol 추출물이, 신장암 세포주인 A498에서는 hexane 추출물이 특히 높은 항암 효과를 보여주었다. 이상의 결과를 볼 때, 장뇌삼과 인삼은 모두 높은 항암 효과를 지니고 있었으며, 그 중에서도 한국산 장뇌삼의 암세포 성장 저해 효능이 가장 뛰어남을 확인할 수 있었다.

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The Radiopharmaceutical Therapy for Multiple Bone Metastases of Cancer (암의 다발성 뼈 전이의 방사성동위원소 치료)

  • Choi, Sang Gyu
    • Journal of Hospice and Palliative Care
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    • v.17 no.4
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    • pp.207-215
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    • 2014
  • Multiple bone metastases are common manifestation of many malignant tumors such as lung cancer, breast cancer, prostate cancer and renal cell carcinoma. Bone metastasis is secondary cancer in the bone, and it can lead to bone pain, fracture, and instability of the weight bearing bones, all of which may profoundly reduce physical activity and life quality. Treatment for bone metastasis is determined by multiple factors including pathology, performance status, involved site, and neurologic status. Treatment strategies for bone metastasis are analgesics, surgery, chemotherapy and radiotherapy. External beam radiotherapy has traditionally been an effective palliative treatment for localized painful bone metastasis. However, in some cases such as multiple bone metastases, especially osteoblastic bone metastasis originated from breast or prostate cancer, the radiopharmaceutical therapy using $^{89}Sr$, $^{186}Re$, $^{188}Re$, $^{153}Sm$ and $^{117m}Sn$ are also useful treatment option because of administrative simplicity (injection), few side effects, low risk of radiation exposure and high response rate. This article offers a concise explanation of the radiopharmaceutical therapy for multiple bone metastases.

Renal Biopsy (신장의 조직 검사)

  • Taek Min Kim;Jeong Yeon Cho;Sang Youn Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.6
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    • pp.1198-1210
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    • 2023
  • The extent of renal biopsy indication is being widened because of the increasing incidence of incidental renal masses; the increasing treatment options for renal cell carcinoma, including ablation therapy and novel targeted treatment; and the increasing incidence of kidney transplantation. However, percutaneous renal biopsy is technically difficult, particularly for beginners, because the skin-to-organ distance is relatively longer than those associated with other organs. In the present review, we will discuss the indications, technical considerations, efficacy, and complications of renal biopsy. Furthermore, we share practical tips of renal biopsy through many examples to help radiologists perform renal biopsy safely and effectively in various situations.

Tumor Resection and Reconstruction in Periacetabular Single Metastases of Renal Cell Carcinoma - A Case Report - (신장 암의 비구주위 단독 전이 환자에서 종양절제 및 재건술 - 증례 보고 -)

  • Shin, Duk-Seop;Han, Dong-Sung
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.113-118
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    • 2007
  • Surgical treatment of pelvic bone tumors represent one of the most complicated problem in musculoskeletal oncology. Because of three dimensional anatomy of the pelvis, tumors reach huge sizes and the diagnosed late relatively to a similar tumors in extremity. Especially, there are limited reconstruction methods to keep the function of hip joint after resection of periacetabular tumors, and the results of reconstruction is not so promissing. We present one case of periacetabular metastatic tumor from renal cell carcinoma, which was resected with wide margin and reconstructed with composite of pasteurized autogenous bone graft and constrained total hip arthroplasty.

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Effects of Lipid Soluble Ginseng Extract on Immune Response (인삼의 지용성 추출물 투여가 면역기능에 미치는 영향)

  • Kim, Dong-Chung;Hwang, Woo-Ik;In, Man-Jin;Lee, Sung-Dong
    • Journal of Ginseng Research
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    • v.32 no.1
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    • pp.19-25
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    • 2008
  • Lipid soluble ginseng extract was administered by oral route in doses of 600 mg/patient daily in cancer patients over 2 months and 6 months. The administration of ginseng extract in cancer patients maintained the ratio of CD4/CD8 and number of the natural killer cell in the normal range during the administration period. Also its administration showed a positive effect on tumor values in 87.5% of patients in 2 month-group and in 50% of patients in 6 month-group, as determined by various cancer markers. Liver and kidney functions maintained normal condition during administration period of 6 months. Although there was no statistical significance, these data suggest that lipid soluble ginseng extract may be useful as an adjuvant therapeutic agent and nutritional supplement for the improvement of immune function and health in cancer patients. This study would provide the basis for the research in which the antitumor and immunopotential activity of lipid soluble ginseng extract for cancer patients are evaluated in formal clinical trial with statistically significant patient number.

Effect of the Extract of Ulmus davidiana Root on the Activity of Enzymes Related to the Removal of Reactive Oxygens in B6C3F1 Mouse Kidney (유근피 추출물이 B6C3F1 마우스 신장에서 반응성 산소종의 발생과 제거에 미치는 영향)

  • Hong, Jong-Yun;Song, Hyuk-Hwan;Lee, Chan
    • Korean Journal of Food Science and Technology
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    • v.38 no.4
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    • pp.577-583
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    • 2006
  • The effect of the extract of Ulmus davidiana root on the activity of enzymes related to the removal of reactive oxygen species was investigated in the B6C3F1 mouse kidney. B6C3F1 mice were divided into five groups and fed for 20 weeks. Reduced xanthine of oxidase activity was observed in groups 4 (group fed with U. davidiana extract after N,N-diethylnitrosamine (DEN) treatment and 5 (group fed with U. davidiana extract from the beginning of DEN treatment) compared to group 2 (group treated with DEN). The level of Mn-superoxidase dismutase tended to increase in the groups after DEN treatment. In group 5, the catalase activity increased and the other groups exhibited an unchanged or slightly decreased level of enzyme. Similar effects were found far glutathione peroxidase. A lower degree of TBARS (thiobarbituric acid reactive substance) formation was estimated in groups 4 and 5, compared to that in DEN treated group 2.