• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.5
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• pp.2180-2186
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• 2011

To find out the protective effects of Kamdootang against accumulation of cadmium in rats, the experimental rats were divided into 2 groups. One group was administered with cadmium alone and the other group administered with cadmium mixed with Kamdootang. Each group has been orally administered with different doses of cadmium such as 1.7 ${\mu}g/g/day$, 3.4 ${\mu}g/g/day$ and 6.8 ${\mu}g/g/day$, respectively, for 1 to 8 weeks. As a results, body weight gained has a tendency to decrease more in the Kamdootang treated groups and non-treated groups than in control group. Cadmium accumulation in kidney showed a significant difference between the Kamdootang treated group and Kamdootang non-treated group. As the experiment period is longer and longer, both groups have got more significantly cadmium accumulation amounts. The kidney system was researched through histopathological observation that Multiple foci of necrosis, hemorrhagic necrosis in glomeruli and cloudy swelling of tubules in kamdootang non-treated group. but tissue lesion of kidney was showed less kamdootang treated group than Kamdootang non-treated group. As remarked above results, when dose low concentrated Cd in rat, Kamdootang was reduced accumulation of Cd. in kidney.

• The Korean Journal of Physiology
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• v.21 no.2
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• pp.201-210
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• 1987

수온변화에 따른 심맥관계 및 신장기능의 변화와 생체실험을 통한 온도에 의한 adrenoceptor의 변형을 알아보기 위해, 무마취 자라에서 $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시 나타나는 혈압, 심박동수 및 신장기능의 변화를 관찰하고, epinephrine 1 ug/kg과 10 ug/kg을 상이한 온도에 노출된 자라의 정맥내 투여하여 나타나는 효과를 비교하였다. 1) $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시킴에 따라 심박동수는 현저히 증가하여 일정하게 유지되었으나, 혈압 및 혈장 renin 활성도는 변화하지 않았다. 온도증가에 의해 뇨량, 사구체여과율 및 전해질 배설량의 현저한 증가를 보였으나 90분부터는 서서히 감소하기 시작하였다. 2) 수온 $18^{\circ}C$에 노출된 자라에서 epinephrine은 dose-dependent한 양상으로 혈압 및 심박동수를 증가시켰으며, 다량의 epinephrine 투여시 작용시간은 현저히 연장되어 있었다. $25^{\circ}C$에 노출된 자라에서는 epinephrine에 의한 혈압상승 효과 및 심박동수 증가는 나타났으나, dose dependency나 작용시간의 차이는 발견할 수 없었다. 3) 동량의 epinephrine에 의한 혈압 및 심박동수의 증가효과는 $18^{\circ}C$와 $25^{\circ}C$에 노출된 자라에서 유의한 차이를 발견할 수 없었으나, $18^{\circ}C$에 노출된 자라에서 epinephrine의 작용시간 및 반감기가 현저히 연장되어 있었다. 4) Epinephrine 투여에 의해 뇨량, 사구체여과율 및 전해질 배설량의 증가를 관찰하였으며, 이는 dose-dependent 양상이었다. 그러나, 신장효과의 유의한 차이는 상이한 온도에 노출된 두 군에서 발견할 수 없었다. 이상의 결과로, 온도증가에 의한 이뇨 및 sodium 배설효과는 혈관이완에 의한 사구체여과율의 증가에 기인한 것으로 사료되며, 상이한 온도에 노출된 자라에서 epinephrine 효과의 차이를 발견할 수 없었던 것은 본 실험에서 가한 좁은 범위의 온도의 변화 내에서는 adrenoceptor의 변형이 나타나지 않을 것이라고 추론하였다. 그러나 저온에서의 epinephrine의 작용시간의 연장은 아마도 epinephrine의 파괴 효소의 활성도의 감소인 것으로 사료된다.

• Journal of Power System Engineering
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• v.13 no.3
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• pp.40-46
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• 2009

This study on the bolt elongation and torque measuring method by ultrasonic nod-destructive method. In the past, The dial gage was used for the elongation measurement of gas turbine bolts. The purpose of this study is to improve the traditional bolt elongation measurement method. The old method using dial gage measures the elongation of the gas turbine bolt. If the length differences among the loading bolts are within the required range, The loading torques of bolts consider as acceptable. But this method can not give the information about torque differences among the loading bolts. It could bring out vibration of turbine due to loading torque differences among the bolts. So the elongation and torque must be measured simultaneously. The new technology using ultrasonic non-destructive method can give the information about bolt elongation and torque. The ultrasonic method basically measures the speed in the bolt material for the calculation the bolt elongation. But the ultrasonic speed varies according to temperature and loading torque of bolts. So the factors of temperature and loading power were investigated and reflected to the calculation of bolt elongation and torque. The results of this study shows the big difference among the bolts torque in the old method and the torque differences among the bolts can be adjusted by reflecting the result of this study. And this torque adjusting method can decrease gas turbine vibration problem due to torque difference among the bolts. So this paper shows ultrasonic method is better than old method for the measurement of bolt elongation and torque.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.15 no.4
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• pp.639-647
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• 2002

A simplified analytical procedure is presented to estimate the reduction of elastic lateral stiffness of steel moment frames arising from the radius-cut dogbone weakening. With the original radius-cut dogbone shape, it is almost impossible or too complicated to integrate analytically the mathematical expressions encountered when applying the conjugate beam method to compute the beam deflection component. In this study, the problem is circumvented by replacing the original radius-cut dogbone with an equivalent dogbone of constant width. The equivalence between the two is established by imposing an equal dogbone elongation criterion. This approach is justified by using a calibrated finite clement analysis. Then, the elastic lateral deflection components from the column, panel zone, and beam are derived for a typical beam-column subassembly. The derived results can be used to evaluate the reduction of the frame lateral stiffness. Case studies conducted within some practical ranges of frame configurations show that the reduction in frame lateral stiffness due to the presence of dogbone cut is on the order of 1 to 2 percent and is reasonably negligible in practical sense.

• Journal of the Korean Society of Propulsion Engineers
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• v.4 no.3
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• pp.55-63
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• 2000

Studies for tube spin forming have been implemented restrictively compared to spinning process, because of the complex of deformation mechanism. Especially there were not many studies by using FEM(Finite Element Method) for overcoming restriction of upper bound method. In this paper, the tube spinning process is analyzed to produce cylindrical body made by titanium alloy. In analysis, processing parameters was obtained by using upper bound method to consider material properties of titanium alloy and finite element analysis was implemented to investigate the flatness and the elongation of the titanium alloy workpiece by using ABAQUS code. The independent variables are ; material properties of workpiece, angles of roller, reduction of diameter. Three variables, two angles of roller and reduction of diameter are optimized by using the upper bound method. In this method, we can estimate the workable power, working force and reduction of diameter, and also the flatness and the elongation of workpiece by the finite elements analysis using ABAQUS/standard. The results indicates that these variables play a critical factors of spinning process for the titanium alloy and the optimum values of these variables.

• Annual Conference on Human and Language Technology
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• 2010.10a
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• pp.68-72
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• 2010

본 논문에서는 그래프 기반의 최대신장트리(Maximum Spanning Tree)를 이용한 한국어 의존구문분석 방법을 제안한다. 우리는 최대신장트리 알고리즘을 한국어의 특성인 지배성분 후위의 원칙과 투사성의 원칙을 적용하여 한국어 의존구문분석에 적합한 알고리즘을 만들었다. 제안한 알고리즘은 기존의 한국어 의존구문분석의 방법들보다 낮은 시간복잡도를 가지며 대용량 말뭉치를 학습하기 위해 증분학습이 가능하고 비교적 학습속도가 빠른 Averaged Perceptron 알고리즘을 사용하였다. 실험결과 제안한 방법은 비교적 열악한 환경인 복문이 포함된 장문의 문장에서도 뛰어난 성능을 보여주었다,

• Journal of Yeungnam Medical Science
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• v.13 no.2
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• pp.261-271
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• 1996

Introduction: Osteoporosis, the most common metabolic bone disorder, is a condition of reduced bone density and increased susceptibility to fractures. Osteoporosis is a major public health problem and a significant cause of morbidity in postmenopausal women. Therefore family physicians as primary care physicians are in a key position for preventing and treating this disorder. So we studied the factors affecting to bone mineral density in postmenopausal women. Materials and Methods: A total of 136 spontaneous postmenopausal women were participated in the study. They have measured spinal bone mineral density by dual energy x-ray absorptiometry from January 1992 to June 1995 at Yeungnam University Hospital. Age, height, weight, age at menarche and menopause, number of child and breast feeding child, history of oral pill ingestion, family history of osteoporosis, amount of milk and coffee ingestion, consumption of tobacco and alcohol and physical activity were assessed by qustionnaire and medical records. Results: The mean age is 55.2 and mean age at menopause is 47.9. Height, weight and physical activity were significantly positive correlated to bone mineral density. But age, duration after menopause and number of child were significantly negative correlated. Also age, height, weight, physical activity and duration after menopause were significantly correlated to % age-matched bone mineral density. In multiple regression analysis, which dependent variable is bone mineral density, duration after menopause, physical activity and weight were significant contributors. Duration after menopause is most the largest contributor. In multiple regression analysis, which dependent variable is % age-matched bone mineral density to adjust the age effect, physical activity and weight were significant contributors. Physical activity is most the largest contributor. Conclusions: Among factors affecting to BMD in postmenopausal women, physical activity and weight were more important factors. Therefore continuous physical activity is significant factor to prevent osteoporosis in postmenopausal women.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.3
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• pp.242-248
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• 2015

Maximum mouth opening is regarded as an important tool used to evaluate the clinical function of temporomandibular joint and the masticatory system. It has been reported that children can also exhibit severe dysfunction or pain in some cases of temporomandibular disorder. The purpose of this study was to measure the normal maximum mouth opening in Korean children and to analyze the correlations between mouth opening and the associated factors. Maximum mouth opening was measured from 151 healthy children between the ages of 2 and 6 years old. Age, height, weight, and mouth width were also recorded. As a result, the mean maximum mouth-opening was $37.72{\pm}5.10mm$. While the values were greater in boys than in girls without statistical significance, the increases of maximum mouth opening based on age, height, weight, and mouth width were significant (p < 0.05). In children, positive correlation coefficients were observed between maximum mouth opening and the associated factors and height showed the highest correlation. In conclusion, we collected data of the normal range of maximum mouth opening in Korean children, and this study can be utilized as a basis in diagnosing pediatric temporomandibular disorder and safety standard of mouth opening during dental procedures.

• Journal of the East Asian Society of Dietary Life
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• v.15 no.2
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• pp.165-170
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• 2005

The present study was aimed to investigate whether ethanol-extract of Nelumbo nucifera has an ameliorative effect on the renal function in high fructose-diet induced hypertensive rats. The urine osmolality (Uosmel) was decreased in rats with high fructose-diet ($60\%$) during the whole experiment period without change of the urine volume (UV). The urinary excretion of sodium and chloride were decrease significantly in rats with fructose induced hypertensive rats, wheras urinary excretion of potassium was increased. The creatinine clearance (CCr) and solute-free water reabsorption were also decreased by treatment of fructose rich diet. Among these renal functional parameters, CCr was partially restored by the administration of ethanol-extract of Nelumbo nucifera. The Uosmol was also partially restored by the administration ethanol-extract of Nelumbo nucifera at the end of the experimental period. Taken together, ethanol-extract of Nelumbo nucifera has the ameliorative effect on glomerular filtration rate in rats with high fructose-diet induced hypertension.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 1999.06a
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• pp.97-117
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• 1999

This study was performed to investigate the effect of pork on the cadmium detoxification in rats. Ninety male Sprague-Dawley rats weighing $125.3{\pm}1.4g$ were divided into five groups based on cadmium treatment(0, 25, 50, 100, 250ppm) and five levels of Cd in AIN-76 purified diet had been fed for 8 weeks. Cadmium was supplemented with a form of $CdCl_2$.. During following 8 weeks of intoxication, casein was replaced by pork and the effect of pork on cadmium- detoxification was compared with casein. After 8 weeks of Cd intake had resulted in apparent cadmium intoxication; reduced growth rate, enlarged kidney and testis, decreased hematocrit value and hemoglobin content in response to the supplemented Cd levels in the diets. Discontinuing cadmium feeding, the body weights were relieved. Pork-fed groups seemed to have higher body weight than casein-fed groups. Hemoglobin content and hematocrit value became normal range at detoxification stage. The weights of liver, kidney, and testis were decreased along with cadmium intake. However, organ weight ratio was not affected by cadmium. Cadmium accumulation in liver and kidney showed a tendency to increase in the cadmium-exposed groups. The levels of metallothionein were also significantly elevated in the tissues of liver in response to the levels of Cd supplemented(p<0.05). Cadmium concentration in kidney was two times higher than that in liver. Cadmium removal rate of liver was higher than that of kidney. Cadmium accumulation of the pork-fed group was lower than that of casein. Especially, the factors which affected the cadmium contents in kidney were $Cd^{***}$ and $Cd{\times}pork^{***}$. Metallothionein(MT) was increased with cadmium, and MT was not likely to be affected by pork. Based on the findings from gross lesion, rats fed 250ppm of Cd were externally emaciated, had exposed penis and observed atrophies of kidney and testis. Histopathological observation seemed that the liver of groups feeding Cd supplemented diets showed cellular degeneration and accumulation of eosinophilic materials in the capillaries. In kidney, rats fed Cd diets had shown tubular epithelium degeneration and lesions of basophilic materials, while testis were weakened in numbers of spermatid and sporadically enlarged of giant cells. But the rats administered cadmium-detoxified diet supplemented pork for 7 weeks were shown individually decreased lesions compared with the rats supplied with casein diet.