• The Science & Technology
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• v.19 no.4 s.203
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• pp.25-31
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• 1986

이 논문은 지난 3월 25~26일 2일간 대한약품공업협회와 재미한국과학기술자협회가 공동주최(과총후원)한 재미과학자초청 「신약개발 심포지엄」에서 발표된 것이다. <편집자>

• Proceedings of the Korea Technology Innovation Society Conference
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• 2004.11a
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• pp.515-525
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• 2004

• Proceedings of the Korea Technology Innovation Society Conference
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• 2015.11a
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• pp.158-164
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• 2015

• The Hankook-Saengyark Bo
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• no.230
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• pp.2-2
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• 1998

'한약비닐팩 인체에 무해'(식약청, 인체에 해로운 항산화제 미검출) - 제천의 '약초향 거리'(작약 목단 꽃길 조성, 특산물 홍보효과) - 큰개암나무 북한풍토 맞게 개량 - '왕가시오갈피' 신종 최초발견, 신약자원 기대

• Communications of the Korean Institute of Information Scientists and Engineers
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• v.31 no.8
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• pp.35-54
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• 2013

• The Science & Technology
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• no.5 s.444
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• pp.42-44
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• 2006

"예쁜 그림 감상하듯 수학문제 풀었어요" - 황준묵 고등과학원 수학부 교수/ "신약개발로 생명 비밀 풀고파" - 김성훈 서울대학교 약학대학 교수/ "테라비트 낸드플래시도 가능할 것" - 황창규 삼성전자 반도체총괄 사장

• Proceedings of the Korea Technology Innovation Society Conference
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• 2016.10a
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• pp.307-318
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• 2016

• Electrical & Electronic Materials
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• v.37 no.1
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• pp.29-35
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• 2024

• Journal of Digital Convergence
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• v.19 no.7
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• pp.33-39
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• 2021

This paper aims to analyze lexical properties of keyword lists extracted from NLT Old Testament Corpus(NOTC), NLT New Testament Corpus(NNTC), and The NLT Bible Corpus(NBC) and identify that text dispersion keyness is more effective than corpus frequency keyness. For this purpose, NOTC including around 570,000 running words and NNTC about 200,000 were compiled after downloading the files from NLT website of Bible Hub. Scott's (2020) WordSmith 8.0 was utilized to extract keyword lists through comparing a target corpus and a reference corpus. The result demonstrated that text dispersion keyness showed lexical properties of keyword lists better than corpus frequency keyness and that the former was a superior measure for generating optimal keyword lists to fully meet content-generalizability and content distinctiveness.

• The Korea Journal of Herbology
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• v.34 no.6
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• pp.99-107
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• 2019

Objective : The present study was conducted to investigate the effects of Chaenomelis Fructus (CF) on the regulation of biogenesis in C2C12 mouse skeletal muscle cells. Methods : C2C12 myoblasts were differentiated into myotubes in 2% horse serum-containing medium for 5 days, and then treated with CF extract at different concentrations for 48 hr. The expression of muscle differentiation markers, myogenin and myosin heavy chain (MHC) and mitochondrial biogenesis-regulating factors, peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC1α), sirtuin1 (Sirt1), nuclear respiratory factor1 (NRF1) and transcription factor A, mitochondrial (TFAM), and the phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase (ACC) were determined in C2C12 myotubes by reverse transcriptase (RT)-polymerase chain reaction (RT-PCR) and western blot, respectively. The cellular glucose levels and total ATP contents were measured by cellular glucose uptake and ATP assays, respectively. Results : Treatment with CF extract (0.01, 0.02, and 0.05 mg/㎖) significantly increased the expression of MHC protein in C2C12 myotubes compared with non-treated cells. CF extract significantly increased the expression of PGC1α and TFAM in the myotubes. Also, CF extract significantly increased glucose uptake levels and ATP contents in the myotubes. Conclusion : CF extract can stimulate C2C12 myoblasts differentiation into myotubes and increase energy production through upregulation of the expression of mitochondrial biogenetic factors in C2C12 mouse skeletal muscle cell. This suggests that CF can help to improve skeletal muscle function with stimulation of the energy metabolism.