• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.113-113
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• 1995

본 연구는 표고버섯에서 분리정제한 렉틴 성분(LEL)을 말초혈액 단핵세포(PBMC)에 반응시켜 사이토카인 유도능을 지질다당류(LPS)와 비교하여 역전사효소 중합반응법(RT-PCR)으로 측정하였다. 측정 대상 사이토카인은 IL-1, IL-2, IL-6, TNF$\alpha$ 및 IFN${\gamma}$의 다섯가지였으며 이들을 대상으로 PBMC에 렉틴을 적용하여 1, 8, 24, 48, 72, 96, 120분 등의 시간대에서 반응시켜 사이토카인의 유전자 발현 유도에 관한 다음의 결과를 얻었다. LEL의 사용 농도에 따른 편도선 림프구(tonsillar lymphocyte)의 TNF$\alpha$ 유전자 발현 양상은 반응 1시간의 경우 LEL의 일부 농도와 LPS 전농도에서 관찰되었으나 반응 40시간째에는 LEL 전농도와 LPS 전농도에서 TNF$\alpha$ 유전자 발현 양상을 관찰할 수 없었다. RT-PCR 결과 원액이나 회석액 재료로부터 관찰된 TNF$\alpha$유전자 band의 강 약 차이는 나타나지 않았다. LEL의 자극에 의한 반응 시간대 별 PBMC에 의한 사이토카인 유전자 발현 양상은 위에서 언급된 다섯가지 사이토카인을 유도, 생성할 수 있다는 것이 확인되었는데, IL-2, IL-6 및 IFN${\gamma}$는 120시간까지 장시간 지속되는 유전자 발현이 가능한 반면 TNF $\alpha$의 생성 양상은 이들 사이토카인의 생성 양상과는 판이하게 반응 1, 8 및 24 시간대까지만 TNF$\alpha$ 유전자 발현을 관찰할 수 있었고 IL-1은 72 시간까지 반응을 나타내는 등 특이적 양상을 보였다. 한편 LPS는 실험에 사용된 전 사이토카인의 유전자 발현을 120시간대까지 반응이 유지됨을 관찰하였기에 LPS가 PBMC의 강력한 사이토카인 유도체임을 입증할 수 있었으며 LEL과 다소 상이한 결과를 보였으나 LEL 또한 PBMC로부터 사이토카인을 생성 유지시킬 수 있는 유도체로 작용함을 확인할 수 있었다.

• Journal of the Korean Society of Marine Environment & Safety
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• v.13 no.3
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• pp.191-198
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• 2007

Marine accidents are increasing as time goes on, in spite of lots of efforts are given. Marine accidents can be classified 3 categories those are ship's condition, navigator's condition and weather condition. In this paper, statistical analysis were carried using marine accidents data from 1997 to 2006. In order to analyze accident rate by time zone, ship's speed and finding distant, SPSS variance analysis was carried out. Results are followed. There was significant difference between time zone 20${\sim}$04 hours and other time zones. The accident rate in daytime was bigger than that at night. In case of the speed at collision, the speed of 5${\sim}$10 knot has significant difference to other speed cases. In finding distant cases, the case of less than 1 mile has significant difference to other distant cases.

• Proceedings of the Korea Society for Industrial Systems Conference
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• 2006.05a
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• pp.211-217
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• 2006

The learning control develops controllers that learn to improve their performance at executing a given task, based on experience performing this specific task. In a previous work, the authors presented an iterative precision of linear decentralized learning control based on p-integrated learning method for the vertical dynamic multiple systems. This paper develops an indirect decentralized learning control based on adaptive control method. The original motivation of the teaming control field was teaming in robots doing repetitive tasks such as on an assembly line. This paper starts with decentralized discrete time systems, and progresses to the robot application, modeling the robot as a time varying linear system in the neighborhood of the nominal trajectory, and using the usual robot controllers that are decentralized, treating each link as if it is independent of any coupling with other links. Error wave propagation method will show up in the numerical simulation for five-bar linkage as a vertical dynamic robot. The methods of learning system are shown up for the iterative precision of each link at each time step in repetition domain. Those can be helped to apply to the vertical multiple dynamic systems for precision quality assurance in the industrial robots and medical equipments.

• Journal of Korean Society for Geospatial Information Science
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• v.24 no.3
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• pp.67-73
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• 2016

The present study evaluated the blocking effect of natural and artificial topography on sunshine duration in the southern coastal area of Haui-do. The geospatial data for the target area was constructed by geographic information system(GIS) data. Three-dimensional modeling based on solar azimuth and altitude angles was conducted for the assessment of sunshine environment. The sunshine area was evaluated over 80~90% of the target area in the daytime, especially in summer. The blocking effect of mountainous terrain on sunshine duration was presented at the northern residential area in the late afternoon. There was also the effect of artificial topography by construction of fill-up bank on sunshine environment at the southern residential area early in the morning and the south-western part of salt field in the late afternoon.

• Journal of Korea Society of Industrial Information Systems
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• v.11 no.2
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• pp.40-47
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• 2006

The learning control develops controllers that learn to improve their performance at executing a given task, based on experience performing this specific task. In a previous work the authors presented an iterative precision of linear decentralized learning control based on p-integrated teaming method for the vertical dynamic multiple systems. This paper develops an indirect decentralized learning control based on adaptive control method. The original motivation of the loaming control field was learning in robots doing repetitive tasks such as on a]1 assembly line. This paper starts with decentralized discrete time systems, and progresses to the robot application, modeling the robot as a time varying linear system in the neighborhood of the nominal trajectory, and using the usual robot controllers that are decentralized, treating each link as if it is independent of any coupling with other links. Error wave propagation method will show up in the numerical simulation for five-bar linkage as a vertical dynamic robot. The methods of learning system are shown up for the iterative precision of each link at each time step in repetition domain. Those can be helped to apply to the vertical multiple dynamic systems for precision quality assurance in the industrial robots and medical equipments.

• Journal of Digital Convergence
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• v.17 no.6
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• pp.77-91
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• 2019

In order to establish a sales strategy for convenience store lunches, this study conducted analysis using association rules based on POS data obtained from convenience stores located in four commercial districts. For this purpose, the data used in the analysis were divided into the time zones from 6:00 am to 8:00 pm, 17:00 pm to 19:00 pm, and the convenience stores according to the commercial areas. As a result of the analysis, it was found that products that were sold together with a lunch box were mainly made of products that could be eaten together with lunch such as milk, beverage, and cotton. However, it was confirmed that there were differences in the types and numbers of the products that were sold together with the lunch boxes of the morning time and the afternoon hours for the other products. These results and approaches are expected to contribute to finding and responding to the needs for goods and services that change as well as convenience stores as well as sociocultural changes.

• Journal of Family Resource Management and Policy Review
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• v.24 no.3
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• pp.19-33
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• 2020

The purpose of this study was to investigate whether paid work time desynchronization affected housework time desynchronization. Time slot data from the Korean Time Use Survey data from 2014 was analyzed. This study included 1,475 married couples aged 20 to 59. They were dual-earner couples, heterosexual couples, and both partners worked during the day, either durong the week or on the weekend. The data was analyzed by the following four groups: weekday-husband, weekday-wife, and weekend-husband, weekend-wife. The results demonstrated that as the desynchronization of paid work increased, the desynchronization of time spent on housework in the weekday-husband and weekend-husband groups also increased. Second, the amount of leisure time did not affect the desynchronization of time spent on housework. Lastly, the amount of time that one person spent on housework increased the housework time desynchronization level. In addition, if the family had children who attended primary, middle, or high school-mothers in the weekday-wife group completed more housework. These results demonstrated that paid work time desynchronization might be a way to decrease the amount of time that dual-earner wives' spent housework.

• Journal of Korean Society of Transportation
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• v.25 no.3
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• pp.137-144
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• 2007

This study involves an analytical approach to determine transit dispatching schedules (headways) Determining a time schedule is an important process in transit system planning. In general, the transit headway should be shorter during the peak hour than at non-peak hours for demand-responsive service. It allows passengers to minimize their waiting time under inelastic, fixed demand conditions. The transit headway should be longer as operating costs increase, and shorter as demand and waiting time increase. Optimal headway depends on the amount of ridership. and each individual vehicle dispatching time depends on the distribution of the ridership. This study provides a theoretical foundation for the dispatching scheme consistent with common sense. Previous research suggested a dispatching scheme with even headway. However, according to this research, that is valid for a specific case when the demand pattern is uniform. This study is a general analysis expanding that previous research. This study suggests an easy method to set a time table without a complex and difficult calculation. Further. if the time axis is changed to the space axis instead, this study could be expanded to address the spacing problems of some facilities such as roads. stations, routes and others.

• Biomedical Science Letters
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• v.6 no.2
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• pp.159-164
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• 2000

We studied the effects of Escherichia coli (E. coli) endotoxin on blood electrolytes levels in rabbits. Endotoxin (5. coli serotype O55 : B5) was injected via rabbits' ear vein : 0.10 mg/kg (Group A) or 0.50 mg/kg (Group B). Blood samples were taken at postendotoxemic 3, 6, 12 and 24 hrs and were analyzed for detections of the levels of blood electrolytes such as $Ca^{++}$, $Mg^{++}$, Na$^{+}$, $K^{+}$ and Cl$^{-}$. As compared to control group, in endotoxin-treated rabbits $Ca^{++}$ levels elevated at 6 hrs but decreased at 24 hrs, $Mg^{++}$ levels were high at 3, 6 and 12 hrs, Na$^{+}$ and $K^{+}$ levels increased at all sampling times and Cl$^{-}$ levels rose at 3, 12 and 24 hrs (p<0.05). Interestingly, endotoxic rabbits having hypermagnesemia (about 4.0 mg/dL) showed severe syndromes such as increased secretion, shock, tachypnea, seizure and/or diarrhea, suggesting that these may be clinical signs of imminent death in rabbits. These observations testify that bacterial endotoxin leads to dyshomeostasis of blood electrolytes and the physiological imbalances may cause fatal disorders and subsequent death.

• Journal of agriculture & life science
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• v.43 no.6
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• pp.67-75
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• 2009

This study was conducted to investigate the effect of herbal (Obtusifolia, Cinnamon, Chinese pepper, Licorice) extracts on the rumen fermentation in vitro. Comparing to the control, in vitro dry matter digestibility was significantly (P<0.05) decreased at zero hour in the Cinnamon and the Chinese pepper, and at three hour after supplementation in the Licorice. The ratio of volatile fatty acids were significant (P<0.05) differences at 3 hour after fermentation only, acetic acid was higher (P<0.05) in the control compare to the herbal extract treatments, but the ratios of butyrate, iso-butyrate, iso-valerate and valerate were lowest in the control. The growth rate of rumen microbes in vitro was significantly (P<0.05) higer in the herbal extract treatments excluding the Obtusifolia than the control during three hour fermentation, but was not significant difference among treatments in the other fermentation times. From above results, even though the extracts of Cinnamon, Chinese pepper and Licorice inclined to inhibit the activity of rumen microbes during early fermentation period, but did not affect on the growth rate of rumen microbes in vitro.