• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.1796-1797
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• 2011

본 연구에서는 기존 오실로메트리(oscillomatry) 혈압측정에서 가압 커프의 영향을 최소화 하기위하여, 캐패시턴스 센서를 추가하여 혈압측정 동안의 혈압 및 혈류의 변화량을 측정하여 얻은 신호로 수축기 혈압 및 이완기 혈압을 추정하였다. 필터를 적용한 캐패시턴스 센서의 값을 피크의 크기에 따른 알고리즘을 적용하였으며 얻어진 혈압값과 기존의 혈압계의 값을 비교분석 하였다. 피험자의 연령은 $25{\pm}4$세의 15명을 기준으로 실험하였으며 알콜 및 운동 등 혈압에 영향을 미치는 요소들에 대해 제한 시켰으며 측정 전 15분의 안정을 취했다. 결과적으로 피험자 15명에 대해 수축기 혈압에서의 오차범위는 ${\pm}4$ mmHg이하로 나타났으며 평균 및 표준편차는 각각 2.13 mmHg 과 1.36 mmHg이었다. 이완기 혈압에서는 오차범위가 11명에 대해 수축기혈압과 같았으며 4명은 ${\pm}7mmHg$이상 이였고 평균과 표준편차는 4.20 mmHg와 2.24 mmHg 로 수축기 혈압에서 오차 및 분산 모두 이완기혈압 추정보다 비교적 정확한 값을 검출했다.

• The Monthly Diabetes
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• s.261
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• pp.14-15
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• 2011

고혈압이 있으면 신장병 발생률이 높아지고, 만성신장병으로 진행될수록 고혈압의 빈도가 증가하는 것으로 나타났다. 대한신장학회 조사에 의하면 건강한 사람의 경우 만성신장병의 발생률이 9.3%인 반면 고혈압환자에서는 21.6%가 신장에 이상이 있는 것으로 밝혀졌다. 또한 고혈압이 심할수록 만성신장병의 발생가능성이 급격히 증가했다. 수축기 혈압이 120mmHg 미만인 정상인은 8.2%에서 만성신장병이 나타났으나 140mmHg(수축기혈압) 이상인 고혈압환자들은 23.1%가 만성신장병을 앓고 있는 것으로 드러났다.

• Journal of Preventive Medicine and Public Health
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• v.21 no.1 s.23
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• pp.99-112
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• 1988

Questionnaires and blood pressure measurements were administered to 279 medical school undergraduates in 1987 to investigate the relationship between psychosocial factors and blood pressure as well as reliability and validity of the Framingham Type A Behavior Scale(FTA). The reliability coefficients of SCL-90-R and nh measured by Spearman-Brown haves split test were $0.57{\sim}0.91$. The factors of FTA extracted by principal component analysis were hard-driving competitiveness factor and impatience factor(2-factor solution) . The total score of nh was positively correlated with relative weight and place raised but the correlations were insignificant, and had significantly positive but weak correlations with depression, anxiety, hostility, paranoid, and psychoticism subscales of SCL-90-R. In the univariate analysis of blood pressures, relative weight and family history were significant in systolic pressure in males and economic status was significant in blood pressures in both sexes. For diastolic pressure, relative weight and frequency of alcohol intake were significant in males and relative weight was in females. After controlling relative weight, the frequency of alcohol intake for diastolic pressure and economic status for systolic pressure were significant in males. The important variables selected by stepwise regression analysis were relative weight and economic status for systolic pressure of males and relative weight and the frequency of alcohol intake for diastolic pressure. At the level of alpha 0.1, depression subscale was added to the model, changing coefficient of determination 0.206 to 0.217. In females, economic status and relative weight were selected for systolic pressure and for diastolic pressure body mass index alone, but the model of blood pressure for females was considered to be unstable due to small sample size(56). FTA was unrelated to the blood pressures in both sexes.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.1
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• pp.45-52
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• 2020

Hypertension often leads to cardiovascular disease and kidney disease, and hypertention is an important worldwide problem. Body mass index (BMI) has an important role for raising blood pressure. Further, hypertension can be affected by both environmental factors and genetic factors. Many single nucleotide polymorphisms have been associated with hypertension. Genome wide association study (GWAS) is a method of confirming a new locus of increasing the risk of disease, and GWAS has confirmed several single nucleotide polymorphisms (SNPs) that are associated with high blood pressure. This study analyzed the relationship between systolic blood pressure, diastolic blood pressure and SNP of the ATP2B1 gene in 994 Koreans. SNPs that showed the highest statistical significance with systolic and diastolic blood pressures were selected on the multiple linear regression analysis. One-way analysis of variance for systolic and diastolic blood pressures was performed, and multiple logistic regression analysis was performed on the risk of hypertension. The P values were two-tailed, and P<0.05 was considered significant. Four SNPs were associated with systolic blood pressure and six SNPs were associated with diastolic blood pressure. In addition, a genotype-based analysis showed significant odds ratios for the risk of hypertension in older men (adjusted OR, 5.743; 95% CI, 1.173~28.121; P=0.031). This study suggests that the ATP2B1 variants affect both the systolic and diastolic blood pressure.

• Journal of Korean Biological Nursing Science
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• v.13 no.3
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• pp.238-244
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• 2011

목적: 이 연구의 목적은 성인의 연령군별 측정자세 변화에 따른 혈압의 변화 정도를 살펴보기 위한 것이다. 방법: 이 연구는 탐색적 조사연구로서 연구대상자는 20세에서 59세까지 성인 136명을 대상으로 만성질병이 없고 연구 목적과 연구방법에 대한 설명을 듣고 연구 참여에 동의한 자를 대상으로 하였다. 수집된 자료는 연령군을 나누어 앙와위, 좌위, 직립위에서 혈압의 차이를 paired t-test로 분석하였으며, 연령군에 따라 운동여부와 건강상태에 차이가 있었으므로 연령과 측정자세에 따른 혈압 변화의 상호작용을 확인하기 위해 repeated measure ANCOVA를 실시하였다. 결과: 초기 성인군(20대와 30대)에서는 자세의 변화에 따른 수축기 및 이완기 혈압의 변화가 없었으나40대와 50대에서는 수축기 혈압에서 앙와위에 비해 좌위(p=.007, p<.001)와 직립위(p<.001, p=.001)에서 유의한 감소가 있었다. 수축기(p=.004)와 이완기(p=.019) 모두에서 연령과 측정자세에 따른 혈압 변화에 유의한 상호작용이 있어 연령군에 따라 자세로 인한 혈압의 변화에 유의한 차이가 있는 것으로 나타났다. 결론: 40세 이후에는 혈압측정시에 자세를 기록하는 것이 중요하며 중년기 이후 자세의 변화에 따른 혈역동의 변화에 특별한 주의를 기울일 필요성이 있다.

• Journal of Korean Academy of Nursing
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• v.26 no.3
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• pp.623-631
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• 1996

간호사가 사용하는 중재로서 관심을 표현하는 방법이며 의사소통의 통로인 접촉의 한 형태로서의 마사지가 이완과 안녕감을 증진시킬 수 있는지를 알아보기 위해 간편하면서도 장소에 거의 구애를 받지 않는 손마사지를 미국 미네소타주에 살고 있는 22명의 한국 이민노인에게 시행하였다. 자료수집 기간은 1992년 12월부터 1993년 6월까지 약 6개월이 소요되었다. 편의표출방법으로 대상자를 선정한 원시실험연구설계로, 독립 변수로 손마사지를 사용하였고 이완행동, 수축기혈압, 이완기 혈압, 맥박수로 측정한 이완의 정도와 안녕감을 종속변수로 사용하였다. 손마사지는 Snyder등이 개발한 방법으로 한 손에 2분 30초씩 5분이 소요되는데 이틀에 한번씩 6회 실시하였다. 안녕 감을 측정하는 Cantril ladder는 10개의 사다리로 된 도구로 첫번 마사지전, 세번째 마사지후, 그리고 여섯번째 마사지후에 대상자로 하여금 직접 사다리 점수를 매기도록 하였다. Luiselli등이 개발한 이완행동 측정도구로 각 마사지 전후에 대상자의 이완정도를 관찰하였고, 마사지 전후에 혈압과 맥박수를 측정하였다. 자료는 paired t-test와 ANOVA, repeated measures ANOVA로 분석하였다. 연구의 결과는 다음과 같다. 1. 1-6회 동안의 마사지전의 이완점수의 평균값과 1-6회 동안의 마사지후의 이완점수의 평균값을 비교한 결과 마사지후에 이완의 정도가 유의하게 증가하였고 (t=10.70, p=.000), repeated measures ANOVA로 검증한 시간에 따른 효과도 유의한 차이를 보였다. 2. 1-6회 동안의 마사지전의 수축기 혈압의 평균값과 1-6회 동안의 마사지후의 수축기 혈압의 평균값을 비교한 결과 마사지후에 수축기 혈압이 유의하게 저하되었 다(t=6.09, p=.000). 3. 1-6회 동안의 마사지전의 이완기 혈압의 평균값과 1-6회 동안의 마사지후의 이완기 혈압의 평균값을 비교한 결과 유의한 차이를 보이지 않았다(t=.27, p=.793). 4. 1-6회 동안의 마사지전의 맥박수의 평균값과 1-6회 동안의 마사지후의 맥박수의 평균값을 비교한 결과 마사지후의 맥박수가 유의하게 감소하였다. (t=4.45, p=.001). 5. Cantril 안녕감의 점수는 유의한 차이를 보이지 않았다(F=2.42, p=1.01)

• Clinical and Experimental Pediatrics
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• v.51 no.9
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• pp.998-1006
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• 2008

Purpose : Hypertension is defined as average systolic blood pressure and/or diastolic blood pressure that is ${\geq}95^{th}$ percentile for gender, age, and height on ${\geq}three$ occasions. Knowing that blood pressure values increase in children as they grow older, the purposes of this study were to measure blood pressure by an oscillometric device and to determine normal values and percentile curves for children. Methods : Systolic and diastolic blood pressures were measured twice with an oscillometric device in 3,545 boys and 3,145 girls under six years of age, in Seoul. Using this data, we determined average blood pressure values and percentile curves based on gender and age; we subdivided these values into blood pressures of $50^{th}$, $90^{th}$, $95^{th}$, and $99^{th}$ percentiles, by percentile of height. The regression coefficients and standard deviations of the systolic and diastolic blood pressure values were obtained from linear regression models. Results : Older boys and girls had higher systolic and diastolic blood pressure values. Older boys and girls in the same percentile of height for age had higher systolic and diastolic blood pressure values. Taller boys and girls within the same age group had higher systolic and diastolic blood pressure values. Conclusion : Blood pressure standards based on gender, age, and height were obtained via an oscillometric method. Llimitation of this study is that the study population was not from the whole country, but exclusively from Seoul. Nonetheless, the data from this study will be helpful in diagnosing and managing hypertension in Korean children.

• Sleep Medicine and Psychophysiology
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• v.9 no.1
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• pp.24-33
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• 2002

Objectives: Nasal continuous positive airway pressure (CPAP) corrected elevated blood pressure (BP) in some studies of obstructive sleep apnea syndrome (OSAS) but not in others. Such inconsistent results in previous studies might be due to differences in factors influencing the effects of CPAP on BP. The factors referred to include BP monitoring techniques, the characteristics of subjects, and method of CPAP application. Therefore, we evaluated the effects of one night CPAP application on BP and heart rate (HR) reactivity using non-invasive beat-to-beat BP measurement in normotensive and hypertensive subjects with OSAS. Methods: Finger arterial BP and oxygen saturation monitoring with nocturnal polysomnography were performed on 10 OSAS patients (mean age $52.2{\pm}12.4\;years$; 9 males, 1 female; respiratory disturbance index (RDI)>5) for one baseline night and another CPAP night. Beat-to-beat measurement of BP and HR was done with finger arterial BP monitor ($Finapres^{(R)}$) and mean arterial oxygen saturation ($SaO_2$) was also measured at 2-second intervals for both nights. We compared the mean values of cardiovascular and respiratory variables between baseline and CPAP nights using Wilcoxon signed ranks test. Delta ($\Delta$) BP, defined as the subtracted value of CPAP night BP from baseline night BP, was correlated with age, body mass index (BMI), baseline night values of BP, BP variability, HR, HR variability, mean $SaO_2$ and respiratory disturbance index (RDI), and CPAP night values of TWT% (total wake time%) and CPAP pressure, using Spearman's correlation. Results: 1) Although increase of mean $SaO_2$ (p<.01) and decrease of RDI (p<.01) were observed on the CPAP night, there were no significant differences in other variables between two nights. 2) However, delta BP tended to increase or decease depending on BP values of the baseline night and age. Delta systolic BP and baseline systolic BP showed a significant positive correlation (p<.01), but delta diastolic BP and baseline diastolic BP did not show a significant correlation except for a positive correlation in wake stage (p<.01). Delta diastolic BP and age showed a significant negative correlation (p<.05) during all stages except for REM stage, but delta systolic BP and age did not. 3) Delta systolic and diastolic BPs did not significantly correlate with other factors, such as BMI, baseline night values of BP variability, HR, HR variability, mean SaO2 and RDI, and CPAP night values of TWT% and CPAP pressure, except for a positive correlation of delta diastolic pressure and TWT% of CPAP night (p<.01). Conclusions: We observed that systolic BP and diastolic BP tended to decrease, increase or remain still in accordance with the systolic BP level of baseline night and aging. We suggest that BP reactivity by CPAP be dealt with as a complex phenomenon rather than a simple undifferentiated BP decrease.

• Childhood Kidney Diseases
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• v.9 no.1
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• pp.8-14
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• 2005

Purpose : This study was peformed to study normative blood pressure data in full-term neonates that may be used to facilitate Identification of neonatal hypertension.Methods : 383 newborns born in our hospital from May 2003 to January 2004 were enrolled in this study Using an oscillometric device(BP-88 NEXT, COLIN Corp.), their blood pressures were measured more than one time within a week after birth. According to each clinical variable such as sex, delivery mode, birth weight, gestational age and presence of maternal disease or perinatal problems, we divided the population into groups and calculated the mean blood pressures of each group. We compared mean blood pressures between the divided groups according to each clinical variable statistically.Results : Mean systolic and diastolic blood pressure of the Population was 70.8$\pm$ 10.9 mmHg and 43.4 $\pm$ 8.0 mmHg, respectively. There was no satistically significant difference in blood pressure according to clinical variables. Mean systolic pressure showed positive correlation with birth weight and gestational age(r=0.1420, 0.03130).Conclusion : Our results are almost in agreement with Zubrow's data from 695 newborns in U.S.A, 1995. Our data may be helpful for early detection and management of neonatal hypertension, thereby maintaining renal function ,and preventing possible complications of renal disease.

• The Journal of the Convergence on Culture Technology
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• v.8 no.3
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• pp.91-97
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• 2022

The purpose of this study was to analyze the measurements of blood pressure and time using manual and automatic blood pressure monitors in various road conditions to verify reliable blood pressure monitor in a moving ambulance. First, the manual blood pressure monitor palpation on unpaved roads showed a systolic pressure deviation of 5 mmHg. However, the automatic blood pressure monitor showed two measurement failures, one reading failure, and the measured systolic pressure deviation was 35 mmHg. The measurement time was 102 seconds faster on average than the automatic blood pressure monitor. Second, the palpation of the manual blood pressure monitor while going over speed bumps remained constant at 130 mmHg. However, the automatic blood pressure monitor had a systolic pressure deviation of 52 mmHg. The measurement time was 61 seconds faster on average than the automatic blood pressure monitor. Finally, the manual blood pressure monitor palpation on the sharp curve road showed a systolic pressure deviation of 5 mmHg. The automatic blood pressure monitor had one reading failure and the measured systolic pressure deviation was 21 mmHg. The measurement time showed that the manual blood pressure monitor was 101 seconds faster than the automatic blood pressure monitor. As a result, in a moving ambulance during an emergency, the manual blood pressure monitor showed high reliability because the blood pressure measurement was constant and the measurement time was short.