• Title/Summary/Keyword: 수명 연장

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Lifespan Extension of Fermented Zizyphus jujuba Fruits in Caenorhabditis elegans (붉은 덕다리버섯 발효 대조(大棗)의 예쁜꼬마선충 수명연장효과)

  • Ji, Byeong-Uk;Park, Sung-Min;Koo, Sungtae;Lim, Byungmook;Yu, Young-Beob
    • Korean Journal of Acupuncture
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    • v.31 no.4
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    • pp.218-224
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    • 2014
  • Objectives : Zizyphus jujuba fruits(ZJF), a traditional Korean medicine has various biological activities such as anti-inflammatory, anti-oxidative and neuro-protective effects. However, it is still unclear whether ZJF has any biological effect on anti-aging. In this study, we examined the effect of ZJF on lifespan and thermal stress in C. elegans. Methods and Results : ZJF water extracts were fermented for 7 days(F7-ZJF) and 14 days(F14-ZJF) by Laetiporus sulphureus to increase secondary metabolites such as aglycone of flavonoids and terpenoids. In the lifespan assay, ZJF water extracts and fermented ZJF were treated on the agar medium plate with age synchronized egg stage of C. elegans. Treatment of F7-ZJF-$200{\mu}g/mL$ with OP-50 E. coli and F14-ZJF-$200{\mu}g/mL$ with OP-50 E. coli significantly increased life span of C. elegans(N2) at thermal stress condition of $25^{\circ}C$. Moreover mRNA levels of lifespan associated HSP 16.1, HSP 70, and HSF-1 were increased at thermal stress condition of $25^{\circ}C$. However, in the equilibration temperature of $20^{\circ}C$ after stress condition of $35^{\circ}C$ for 2 hr, F-14-ZJF-$200{\mu}g/mL$ treatment decreased the levels of heat shock protein in hsp16.2/GFP C. elegans. Conclusions : Our study indicates that prolong role of fermented-ZJF in C. elegans is mediated by control HSPs production.

Experimental Determination of Complex Moduli and Internal Damping of Laminated Composites (적층 복합재료의 내부감쇠와 복소탄성계수 측정에 관한 연구)

  • Lee, Jae-Hyeok;Park, Se-Man;Kim, Hyeong-Sam
    • Korean Journal of Materials Research
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    • v.8 no.10
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    • pp.905-911
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    • 1998
  • Damping is a property for materials and systems to dissipate energy during periodic deformations. Generally, damping causes stiff decrease in amplitudes and shifts in phases. Also, even at resonance, amplitudes are substantially attenuated. This phenomenon of damping helps in reducing stresses developed during vibrations and consequently improves fatigue lives of materials. In this work internal damping and complex moduli are experimentally determined. An impulse technique is utilized in experiments and cantilever beams are selected as test subjects for the measurements of flextural vibrations since the beams lend themselves easily as simplistic ideal models. A resonance method is employed to determine resonance frequencies which are utilized to compute storage moduli. Also, loss moduli are evaluated from damping capacities and storage moduli. The storage and loss moduli combined yield complex moduli. Finally internal damping is evaluated from bandwidth technique, the real component of the transfer function.

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IDE-LEACH Protocol for Trust and Energy Efficient Operation of WSN Environment (WSN의 에너지 효율적 운영을 위한 신뢰성이 보장된 IDE-LEACH 프로토콜)

  • Cho, Young-Bok;Woo, Seng-Hee;Lee, Sang-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38B no.10
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    • pp.801-807
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    • 2013
  • WSN consists of hundreds to thousands of sensor nodes. In order to solve the problem of energy consumption imbalance cluster head is reelected in every round, while node authentication scheme is utilized for secure communication. However, re-clustering increases the overhead of sensor nodes and during the node authentication phase the frequent AREQ/AREP message exchange also increases the overhead. Therefore, a secure and energy efficient protocol, by which overhead of sensor nodes is reduced and long time communication is achieved, is required for wireless sensor network. In this paper, an energy efficient and reliable IDE-LEACH protocol for WSN is proposed. The proposed protocol is prolongs networks lifetime about average 20% compared to the LEACH-based protocols and all attending nodes in communication form BS authentication consisted of trusted nodes.

A study on a target-tracking and noncontact type biosignal measurment system Using IR-Radar and Pan-Tilt system (원격 비접촉식 목표 추적형 생체신호측정시스템에 관한 연구)

  • Choi, Kwang-Wook;Kim, Cheol-Sung;Yang, Chul-Seung;Lee, Jeong-Gi
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.9
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    • pp.2237-2242
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    • 2014
  • As Single households increases for reason of communication development, extending human life, there are many problems occuring all over the world. In order to solve this problem with an invasion of privacy and manintain a healthy life, this paper suggest non-contact type bio-signal measurement system using IR-Radar, displacement sensor and Pan-Tilt system. The proposed system can increse the distance of measured respiration from 1m to over 8m, which is comprised of two IR-Radar for location tracking, one displacement sensor for non-contact type bio-signal measurement and one stepping motor drive system. The proposed system is verified through experiments and were confirmed the possibility.

LED Lighting Monitoring System Using Bluetooth BLE (Bluetooth BLE를 활용한 LED 조명 관제시스템에 관한 연구)

  • Oh, Am-suk
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.2
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    • pp.367-372
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    • 2017
  • LED illumination has been developed from simple illumination to human oriented multi-functional system depending on the IT convergence trends. Thus, the convergence of IT technology such as various types of sensor and communication functions with application software can make saving of energy, and there are also several needs about the tailor-made illuminations requirements for the diverse users who want to take their own colors, strengths of the light. For the adaption of these kinds of intelligent system illumination, user oriented sensor and control should be possible. The LED lighting control system transmits and receives data via the Bluetooth mesh network and provides functions such as LED lighting control, LED lighting condition monitoring, energy usage monitoring, and energy peak point management. Therefore, in this paper, we suggest wireless communication platform and control system for the LED illumination control. We can expect life extension of LED illumination, and energy saving through this suggested system.

Investigations on Corrosion Environment of Buried Water Pipelines in Seoul Area (서울지역 매설 상수배관 부식환경 조사)

  • 유중권;전경수;고영태;박경완;조용범;이선엽;조성호
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 1998.05a
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    • pp.4-4
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    • 1998
  • 서울 및 서울 인근 주민들의 식수 공급을 위하여 1978년에 건설된 매설 상수배관은 전기방식 조처없이 콜탈에나벨만으로 피복된채 지하철 및 각종 전기설비가 복잡하게 산재된 서울지역에서 근 20년 유지되고 있다. 따라서 이 배관에 대한 부식 상태를 파악하는 것이 배관의 안전성 확보 및 대책수립, 배관수명의 연장, 중단없는 상수공급 동의 차원에서 매우 중요하다. 이 조사의 목적은 건설후 20년이 경과하여 노후된 매설 상수배관에 대한 기본적인 부식환경 및 피복 상태를 조사하여, 부식상태를 진단하고 향후 대책을 세우기 위한 기초 자료를 확보하는 것이다. 조사의 대상은 1978년에 건설된 서울지역 매설 상수배관 103 Km이었으며, 주요 조사 내용은 토양의 pH, 토양비저항과 같은 기초적인 부식환경조사, 전 배관에 대한 부식전위측정, 부식환경 조사로부터 판정된 부식 우려구간을 대상으로 피복손상부 탐측 및 시험굴착, 그리고 상기 조사의 결과를 검토하는 것이다. 조사 결과, 기본적인 부식환경 변수로 예상되던 토양의 전기비저항, 습도, pH는 부 식전위 및 토양종류와 상관관계를 보이지 않았으며, 상수배관 주변의 토양비저항은 대부분 8,000 ~ 10,000 ${\Omega}{\cdot}cm$, 토양 pH는 대부분 5와 6사이에 집중되었다. 전체적으로 볼 때 매설 상수배관은 예상보다 양호한 배관 상태를 유지하고 있다고 판단되나, 일부 간섭구간은 방식보완이 필요한 것으로 조사되었다. 즉 일부 간섭에 의한 미방식 지역은 배류기나 희생양극 설치와 같은 조속한 방식보완 조치가 필요하며, 과방식이 우려되는 곳은 강제배류기의 출력을 크게 낮추는 것이 필요하다. 이때 부식전위가 크게 올라가는 지점이 있으면 부근 가까운 지하철 레일과 선택배류기로 연결하는 것이 바람직하다.

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Anti-inflammatory and Anti-tumor Effects of Tetragonia tetragonoides Extracts (번행초 추출물의 항염증 및 종양억제 효과)

  • Choi, Hye Jung;Yee, Sung-Tae;Kwon, Gi-Seok;Joo, Woo Hong
    • Microbiology and Biotechnology Letters
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    • v.43 no.4
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    • pp.391-395
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    • 2015
  • We examined the anti-inflammatory effect and anti-tumor activity of Tetragonia tetragonioides crude extracts and fractions. The anti-inflammatory activity of T. tetragonioides was exuded through the inhibition of lipopolysaccharide (LPS, $1{\mu}g/ml$), induced nitric oxide (NO) and interleukin (IL)-$1{\beta}$ production. The production of IL-6 and tumor necrosis factor $(TNF)-{\alpha}$ also decreased in LPS induced RAW264.7 cells after treatment with polysaccharide (PS) fraction. Furthermore, the hexane (HX) fraction strongly inhibited the granulocytes macrophage-colony stimulating factor (GM-CSF) production. In ICR mice previously inoculated with Sarcoma 180, the life prolongation effects were 16.67% with an intraperitoneal injection of methanol (MeOH) extract and polysaccharide fraction at a dose of 100 mg/kg/day. The results are an important preliminary step toward the development of effective anti-inflammatory and anti-tumor agents using T. tetragonioides.

A Study on Indoor Environment for Welfare Centers of the Aged with Regard to Behavioral Characteristics. of the Aged. - Focusing on welfare centers for elderly People in Gwangju - (노인의 행태를 고려한 노인복지시설의 실내환경 현황에 관한 연구 - 광주광역시 노인복지회관을 중심으로 -)

  • Yoo, Eun-Young;Kim, Moon-Duck
    • Archives of design research
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    • v.18 no.3 s.61
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    • pp.181-190
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    • 2005
  • Although the national government prepares and implements planning for securing various services and facilities based on the needs of welfare centers for leisure of the aged according to the increase of life expectancy. These efforts are still beyond the satisfaction for the needs of the aged. These efforts are only polling on in terms of the increase in quantity, and so therefore there is total lack of high level of welfare facilities for the aged with regard to the consumers' characteristics and behavior attitudes. Under these considerations, this study aims at investigating through indoor space check list, the reality of whether the present welfare centers for the aged are designed with the application of the characteristics and behavior attitudes of the aged to the indoor space. The results of this study are going to be utilized as basic materials for future designs that may consider the behavioral attitudes of the aged and be able to increase their quality of leisure and welfare when building welfare centers for the aged in the future.

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A Cluster-Based Top-k Query Processing Algorithm in Wireless Sensor Networks (무선 센서 네트워크에서 클러스터 기반의 Top-k 질의 처리)

  • Yeo, Myung-Ho;Seong, Dong-Ook;Yoo, Jae-Soo
    • Journal of KIISE:Databases
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    • v.36 no.4
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    • pp.306-313
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    • 2009
  • Top-k queries are issued to find out the highest (or lowest) readings in many sensor applications. Many top-k query processing algorithms are proposed to reduce energy consumption; FILA installs a filter at each sensor node and suppress unnecessary sensor updates; PRIM allots priorities to sensor nodes and collects the minimal number of sensor reading according to the priorities. However, if many sensor reading converge into the same range of sensor values, it leads to a problem that many false positives are occurred. In this paper, we propose a cluster-based approach to reduce them effectively. Our proposed algorithm operates in two phases: top-k query processing in the cluster level and top-k query processing in the tree level. False positives are effectively filtered out in each level. Performance evaluations show that our proposed algorithm reduces about 70% false positives and achieves about 105% better performance than the existing top-k algorithms in terms of the network lifetime.

Remote Vital Sign Monitoring System Based on Wireless Sensor Network using Ad-Hoc Routing (애드혹 라우팅을 이용한 무선센서네트워크 기반의 원격 생체신호 모니터링 시스템)

  • Walia Gaurav;Lee Young-Dong;Chung Wan-Young
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.426-429
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    • 2006
  • A distributed healthcare monitoring system prototype for clinical and trauma patients, was developed, using wireless sensor network node. The proposed system aimed to measure various vital physiological health parameters like ECG and body temperature of patients and elderly persons and transfer his/ her health status wirelessly in Ad-hoc network, to remote base station which was connected to doctor's PDA/PC or to a hospital's main Server using wireless sensor node. The system also aims to save the cost of healthcare facility for patients and the operating power of the system because sensor network is deployed widely and the distance from sensor to base station was shorter than in general centralized system. The wireless data communication will follow IEEE 802.15.4 frequency communication with ad-hoc routing thus enabling every motes attached to patients, to form a wireless data network to send data to base-station, providing mobility and convenience to the users in home environment.

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