• Journal of Biomedical Engineering Research
• /
• v.22 no.5
• /
• pp.413-418
• /
• 2001

We developed shunt valves used to treat patients with hydrocephalus. The valves under development were constant Pressure type ventriculoperitoneal (VP) calves made of silicone elastomer. In vitro experiments showed that our valves had similar Pressure-flow control characteristics to the valved currently available in the market. Our valves also showed competent performance in the 28 days of continuous pumping tests acording to the IS07197 specifications. We artificially inducted hydrocephalus to a 10kg beagle do9. The size of the ventricles of the dog was substantially increased and the dog showed abnormal behavior. After our valve being implanted, the ventricles recovered regular size with the normal behavior observed in the dog. The flow orifice of the shunt valve diaphragm was in the older of 10$\mu$m during calve operation and hence the pressure-flow control characteristics tended to change by a small chance in the valve dimension. Therefore, precision design and manufacturing techniques were necessary for successful operations of the shunt valves .

• Journal of Korean Society of Disaster and Security
• /
• v.11 no.2
• /
• pp.17-28
• /
• 2018

The purpose of this study is to investigate the effect of underground facilities around excavation zone on groundwater flow characteristics during excavation. The scenarios were constructed considering the size of the underground facility, the separation distance, and the hydraulic gradient. As a result, as the size of the underground facility increases, the difference of head and the hydraulic gradient become large. The shorter the separation distance of underground facility is, the more the difference of head and the hydraulic gradient occur. The effect of hydraulic gradient on model area was relatively small. As a result of analysis of groundwater flow rate for the scenario, groundwater flow rate tends to decrease as the size of underground facility increases or groundwater flow rate tends to decrease as the separation distance decreases. It is necessary to examine the effect of underground facilities on the groundwater flow analysis in the ground excavation.

• Journal of Soil and Groundwater Environment
• /
• v.11 no.2
• /
• pp.45-55
• /
• 2006

A 2-D unconfined flow model is developed to analyze annual variations of groundwater level and bank filtration rate (BFR) for an experimental riverbank filtration site in Koryeong, Korea. Two types of boundary conditions are examined for the river boundary in the conceptual model: the static head condition that uses the average water level of the river and the dynamic cyclic condition that incorporates annual fluctuation of water level. Simulations show that the estimated BFR ranges $74.3{\sim}87.0%$ annually with the mean of 82.4% for the static head boundary condition and $52.7{\sim}98.1%$ with the mean of 78.5% for the dynamic cyclic condition. The results illustrate that the dynamic cyclic condition should be used for accurate evaluation of BFR. Simulations also show that increase of the distance between the river and the pumping wells slightly decreases BFR up to 4%, and thereby indicate that it is not a critical factor to be accounted for in designing BFR of the bank filtration system. A sensitivity analysis is performed to examine the effects of model parameters such as hydraulic conductivity and specific yield of the aquifer, recharge rate, and pumping rate. The results demonstrate that the average groundwater level and BFR are most sensitive to both the pumping rate and the recharge rate, while the water level of the pumping wells is sensitive to the hydraulic conductivity and the pumping rate.

• Geotechnical Engineering
• /
• v.8 no.2
• /
• pp.59-70
• /
• 1992

This work is to study experimentally the measurment of pore air pressure according to rainfall in colluvium model and the characteristics of pore water pressure according to increasement of artesian ground water head. After modeling a geological feature of the Tertiary formation, the experiment was performed about sixty times on three kinds of soil. This experimental results showed the variation of pore water and pore air pressures with time, the change of void ratio and appling pressure head in the nonsaturated soil. It can be also expressed by the final pore water and the air reaction ratios and then formularizing the relationship between the permeability coefficient and the void ratio. In the results of this experiment, the patterns of the pore water pressure reaction are classified by the step-type and the wave-type, and the time-lag to reach final point of pore water pressure is in order sand, sandy silt and clayey sand.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2010.05a
• /
• pp.654-658
• /
• 2010

과부하 맨홀의 손실계수에 대한 연구는 국내외에서 지속적으로 수행되어 왔다. 그러나 실제 하수관거 설계 및 평가에 이러한 손실계수의 적용여부에 따른 맨홀의 흐름변화에 대한 연구는 이루어진바 없다. 따라서 본 연구에서는 실무에서 하수관거 설계 및 평가 시 가장 많이 사용되는 상용프로그램 SWMM 모형을 활용하여 손실계수 적용 여부에 따른 맨홀의 수두변화를 비교 하였다. 손실계수의 영향을 확인하기 위해 가상유역을 설정하였으며, 이때 가상유역 내에는 4개의 합류맨홀을 포함하고 있고, 그 외 맨홀은 중간 맨홀 및 $90^{\circ}$ 접합맨홀로 이루어져 있다. 손실계수는 윤세의 등(2008, 2009, 2010)이 제시한 값을 적용하였다. 과부하 맨홀에 손실계수를 적용한 결과 맨홀 내 수심은 증가하였고 동수경사선이 높아짐으로써 손실계수 적용 후 침수가 발생하는 맨홀도 나타났다. 따라서 도시유역의 하수관거 평가 시 맨홀에 과부하가 발생하는 경우에는 손실계수를 적용 후 평가가 이루어져야 할 것으로 판단된다.

• Pediatric Infection and Vaccine
• /
• v.12 no.2
• /
• pp.195-201
• /
• 2005

Objective : The purpose of this study is to investigate the epidemiology and clinical characteristics of herpes zoster in children and adolescents in Korea and to delineate the effects of varicella vaccine on the incidence of zoster and its complication. Methods : We evaluated the clinical records of 201 patients younger than 20 years admitted for herpes zoster at four hospitals located in Kyung-Gi provine during Jul. 1995 to Jun. 2005. Results : The admitted patients for herpes zoster have increased during the past 10 years. The effects of varicella vaccine on the incidence of herpes zoster remain inconclusive in this study. Only twelve percent of the study patients had underlying diseases. In 34(17%) of 201 patients, complications were confirmed during hospitalization. Of 34 patients, meningitis occurred most frequently. Irrespective of varicella vaccination, occurrence of complications was higher in patients who had experienced varicella previously(=overt varicella infection) than patients who had not(=subclinical varicella infection). In case of no previous varicella history, we found complications to be much lower in those who had received the varicella vaccine than those who had not. Conclusion : We cannot conclude whether the varicella vaccine has an effect on the increasing incidence of zoster. We can conclude that the subclinical varicella infection or vaccination for varicella might lead to a decreased incidence of zoster complications.

• Journal of Korean Neurosurgical Society
• /
• v.29 no.11
• /
• pp.1421-1428
• /
• 2000

Objectives : The aim of this study is to evaluate the sequential metabolic changes in experimental hydrocephalus and the clinical applicability to the diagnosis and prognosis of hydrocephalus using proton MR spectroscopy. Methods : Hydrocephalus was experimentally induced in 30 cats(2-3kg body weight) by injecting 1ml of sterile kaolin suspension(250mg/ml) into the cisterna magna. Proton MRS was performed with a 1.5 T MRI/MRS unit (Vision Plus, Siemens) at pre-treatment and at 1, 3, 7, 14, 21, and 28 days after the kaolin injection. PRESS(TR/TE＝1500/270msec) technique was employed. The major metabolites which include N-acetyl aspartate (NAA), creatine(Cr), choline(Cho), and lactate(Lac) were quantitatively analyzed and the relative concentrations ratios were evaluated. Multislice $T_2$-weighted images were also obtained using fast spin echo sequence(TR/TE＝ 2500/96msec) to monitor the morphologic changes along with progression of hydrocephalus. Results : Hydrocephalus was successfully induced in all 30 cats. Twenty five cats died within 3 days and one at the end of the second week. In all animals, the NAA/Cr ratios initially decreased during the acute stage. In 4 surviving cats, the NAA/Cr ratios initially decreased during the acute stage(<14 days) and then gradually increased to the prekaolin level as follows : pre-kaolin($1.49{\pm}0.04$), day 1($1.11{\pm}0.07$), day 7($1.17{\pm}0.04$), day 14($1.40{\pm}0.03$), day 21 ($1.46{\pm}0.06$), day 28($1.43{\pm}0.03$). These levels were relatively well correlated with the symptomatologic improvement. Lactate peak, which reflects the evidence of ischemia, did not appear throughout the entire period except in one case which expired at the end of the second week. Conclusions : The NAA/Cr ratio of the sequential proton MRS in kaolin-induced hydrocephalic cats reflects a metabolic aspect of the hydrocephalus at each stage. A decreased NAA level at the early stage is from both neuronal and axonal damage which may provide diagnostic information in the acute stage of hydrocephalus. In addition, the initial fall of NAA/Cr ratio and recovery in the late stage, when no lactate peak emerges, may suggest that the main insult of the parenchyma is not to the neuron itself but to the axon, which may be related to a good prognosis. However, emergence of the lactate peak and unrecoverable NAA/Cr at the end of the acute phase may be a poor prognostic factor. In the chronic stage, recovery of NAA/Cr ratio may provide a diagnostic clue for the differentiation between hydrocephalus and cortical atrophy.

• Journal of the Korean Geotechnical Society
• /
• v.26 no.5
• /
• pp.37-48
• /
• 2010

In this study, the seepage flow monitoring method by the hydraulic head loss rate was developed for the purpose of application to offshore construction site enclosed by cofferdams in which seepage force varies periodically. The amount of the hydraulic head loss rate newly defined in this graph was in a range between 0 and 1. The zero of the rate means the existence of flow with no seepage resistance. The 1 of the rate means no seepage flow through the ground. The closer to 1 the coefficient of determinant in the hydraulic head loss graph is, the more the ground through which seepage water flows is stable. The closer to 0 the coefficient of determinant in the hydraulic head loss graph is, the more the ground through which seepage water flows was unstable and the higher the possibilities of existence of empty space or of occurrence of piping on the seepage flow pass in the ground is. The hydraulic head loss graph makes it possible to monitor sensitively the situation of seepage flow state, and the graph helps to understand easily the seepage flow state at the specific section on the whole cofferdam.

• 한국신재생에너지학회:학술대회논문집
• /
• 2006.06a
• /
• pp.455-458
• /
• 2006

본 연구는 자연에너지를 이용하는 모든 냉 난방기술 중에서 에너지효율이 가장 높은 것으로 알려져 있으며 에너지 자원이 부족하고 에너지비용이 높은 상황에서 반드시 필요한 기술인 지하수를 이용한 건물의 냉 난방을 수행하는 스탠딩컬럼웰 지열히트펌프 기술을 운영함에 따른 지하수에 미치는 환경영향을 평가하기 위해 수행되었다. 즉 스탠딩컬럼웰을 적용한 지열히트펌프 시설이 가동되고 있는 주변지역의 지하수질 및 지하수위의 변화를 평가하기 위하여 지하수 환경영향평가를 실시하였다. 연구결과, 히트펌프의 유입수 및 유출수, 그리고 주변 지역의 수질은 지하수 수질기준 및 공업용수, 생활용수 수질기준에 적합한 안정적인 수질을 나타내었으며, 시설 운영에 따른 지하수 오염은 거의 없는 것으로 판단된다. 또한 지열히트펌프에 이용되는 4개의 양수정에 의한 주변 지역의 지하수위 변화등의 영향을 예측하기 위하여 취수가 없는 상태와 양수정당 취수량을 $50m^3/day$로 증가시켰을 경우를 가정하여 지하수두를 분석한 결과 취수량을 증가시켰을 경우 지하수두가 약2,.2m 감소하는 것으로 나타나 조사지역내의 지하수 거동은 양수정 가동조건과 주변지역에 분포되어 있는 정천의 취수량 변화에 따라 민감하게 반응하는 것으로 나타났다.

• Journal of the Korean Society of Groundwater Environment
• /
• v.5 no.3
• /
• pp.123-128
• /
• 1998

Leaky aquifer (two-aquifer) system in this study consist of an upper unconfined and a lower confined aquifer with a leaky layer between them. It is assumed that water is withdrawn from the confined aquifer of the aquifer system, the upper unconfined aquifer will be affected by the leaky aquifer separating the upper and lower aquifer. In order to analyze the leaky aquifer, the determination of hydraulic parameters is needed. In this paper, hydraulic parameters are suggested by improved SM (slope-matching) method. To know variation of groundwater head in leaky aquifer systems, an numerical scheme is made using the finite difference method. To verify the numerical scheme, its solution is compared to analytical one. The solution of them agrees well in one-dimensional system at steady-state condition. And heads of groundwader are computed upper and lower aquifer in two-dimensional system.