• Journal of Yeungnam Medical Science
• /
• v.6 no.1
• /
• pp.43-46
• /
• 1989

Primary peptic ulcer disease is not known to be the result of underlying illness or traum. These are most frequently duodenal or prepyloric. Since clinical features of peptic ulcer in children can easily be confused with many other disorders, the diagnosis is usually made when one of the more dramatic presentations, such as perforation, bleeding and obstruction. Recently, we experienced 2 cases of duodenal obstruction due to peptic ulcer in children. So, we report it with review of references.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.11
• /
• pp.3494-3499
• /
• 2009

The stability of omeprazole in the aqueous solutions containing loxoprofen or Sodium bicarbonate was examined at room temperature. Loxoprofen or Sodium bicarbonate (60 mg) was added to omeprazole (600 ${\mu}g$/ml) solution to check the stability profile. Then, the solution was kept at room temperature for 80 hours. The concentration was assayed at each concentration by stability-indicating High performance liquid chromatography (HPLC) method. Aliquots of the solution were withdrawn at specified time intervals and assayed by chromatographic analysis for intact omeprazole. The relation between omeprazole concentration and peak area was linear from 5 to 160 ${\mu}g$/ml. The analysis method was precise with relative standard deviation (% RSD) no greater than 3.05 %. The remaining percentage-time curves revealed that omeprazole was degraded rapidly as functions of time and temperature following pseudo first-order kinetics. In conclusion, the stability of omeprazole was significantly affected by liquid solutions mixed with alkalizer (Sodium carbonate) or the NSAIDs (loxoprofen).

• Journal of Convergence for Information Technology
• /
• v.10 no.10
• /
• pp.109-114
• /
• 2020

The aim of the study was to observe the influence and related mechanism of rebamipide on the intestinal contraction. Intestinal contraction includes the activation of thick or thin filament regulation. However, there are few reports addressing the question whether this regulation is involved in rebamipide-induced regulation. We hypothesized that rebamipide plays a role in intestinal contraction evoked by carbachol in rat intestine. Interestingly, rebamipide alone didn't inhibit and rather slightly increased the contraction in the denuded muscle. Therefore, rebamipide alone and together with indomethacin increases the ileal contraction suggesting that additional pathways might be involved in the regulation of ileal contractility. In conclusion, rebamipide has some effect on the regulation of contractility and anti-ulcer by NSAIDs.

• Journal of Yeungnam Medical Science
• /
• v.13 no.1
• /
• pp.1-10
• /
• 1996

• 대한핵의학회:학술대회논문집
• /
• 1986.05a
• /
• pp.119.3-120
• /
• 1986

• The Korean Chronic Disease News
• /
• no.110
• /
• pp.8-8
• /
• 1990

• The Korean Chronic Disease News
• /
• no.110
• /
• pp.9-9
• /
• 1990

• 건강소식
• /
• v.34 no.6
• /
• pp.18-19
• /
• 2010

한 유제품 CF로 인해 누구나 한 번쯤은 들어보았을 헬리코박터 파이로리(Helicobacter Pylori). 헬리코박터 파이로리균은 위 점막에 기생하는 나선균으로 위나선균으로도 불린다. 이 세균은 환자에게서 분리된 균주마다 서로 다른 유전체 구조를 가진 특이한 세균집단으로 만성 전정부 위염, 소화성궤양, 위 MALT(점막연관림프조직형) 림프종, 위암 등의 원인이다.

• The Korean Nurse
• /
• v.25 no.1 s.134
• /
• pp.85-101
• /
• 1986

This study on stressful life events and coping methods of peptic ulcer patients and non-peptic ulcer peoples was applied to people who was divided into two groups from Oct. 28 to Nov. 16, 1985. One is patients who were conformed by gastroscopy in medical

• The Korean Journal of Food And Nutrition
• /
• v.10 no.2
• /
• pp.186-192
• /
• 1997

Endoscopic diagnosis and medical management from K43 and C45 patients, whose sex, occupation, character and life patterns are quite different each other, were discussed. The K43 was patient with erosive gastritis, which may caused by maldietary habits and life stresses. Although the effective drugs such as H2-receptor antagonists with atacids, H+/K+-pump inhibitors, prokinetics, colloidal bismuth, and sucralfates, were administrated for long time, symptomatic relief of abdominal pain was not improved. The tests of clinical phathology and abdominal sonogram were normal, visceral hypersensitivity was appeared from barostat test of stomach. However C45 had taken headache during every day life, and endoscopically confirmed as a gastric·duodenal ulcer patiant, which may caused by chronic use of NSAIDs. The her ulceric symptoms were suppressed from active stage to healing stage by using combination therapy for H. pylori with traditional antipeptic ulcer drugs, where as amitriptyline was administrated to the K43 but not effective. Nonulcer dyspepsia and irritable bowel syndrome is pooly defined, and affect about 15% of the population annually in U. S. A. but don't seek medical care. Author would like to point out that statistics for visceral pains are absent in Korea.