• Journal of Life Science
• /
• v.6 no.4
• /
• pp.304-312
• /
• 1996

In the present report, a p[ossibility of the interaction fo Ser-33 and Asp-112 residues in folding of tryptophan synthase $\alpha$ subunit was explored by examining the effect of single or double substitution of these residues on folding of $\alpha$ subunit in E. coli. $\alpha$ subunit of which Ser-33 was substituted with Leu (SL33) was accumulated as insoluble aggregate form, when overproduced in E. coli, whereas $\alpha$ subunit of which Asp-112 was replaced by Asn (DN112) or Gly (DG112) was accumulated as soluble form to the similar extent as wild type $\alpha$ subunit was. When these alterations were combined into one protein, the synergistic effect of residues 33 and 112 on the amount of aggregate form was shown. The amount of doubly altered SL33/DG112 $\alpha$ subunit as aggregate form was increased 5-13 fold that of SL33 $\alpha$ subunit, and the amount of SL33/DG112 $\alpha$ subunit as aggregate form was decreased 3-4 fold that of SL33 $\alpha$ subunit. Aggregates are derived from the specific association of partially folded or unassembled subunits in the folding process. Therefore, this result suggests that residues 33 and 112 of $\alpha$ subunit may unteract during the folding of this enzyme in E. coli.

• The Journal of the Convergence on Culture Technology
• /
• v.9 no.6
• /
• pp.795-799
• /
• 2023

The Canadian military participated in World War I and felt the limitations of the recruitment system through the continuous shortage of troops caused by the prolonged war, therefore expanded the role and scope of female manpower. The use of female manpower, which began with medical support for the first time, increased its necessity and importance as medical support personnel were dispatched overseas and women's manpower was expanded to combat support missions for the Army, Navy, and Air Force. Since then, the proportion of female manpower has been limited to 1.5% of the total number of employees at the end of the Second World War and the reduction of troops and the dismantling of the women's unit. In this situation, the Austrian Defence Force gradually accepts the recommendation of the Royal Canadian Women's Status Committee to improve the service conditions of women, marking a turning point in expanding the role of women in the Canadian military. The the Austrian Defence Force conducted long-term combat experiments to increase the proportion and role of female manpower, increasing reliability through observation and analysis to prove whether female manpower is suitable for combat troops. Korea also wants to draw implications for the future direction by comparing the history and current appearance of the Canadian military's use of female manpower with the Korean military at a time when the problem of a shortage of troops is emerging due to the recent decline in fertility and low birth rates.

• The Journal of Society for e-Business Studies
• /
• v.21 no.2
• /
• pp.1-22
• /
• 2016

News contents has been collected, selected, edited and sometimes distorted by the news recommendation mechanisms of online portals in nowadays. Prior studies had not confirmed the consensus of newsworthiness, and they had not tried to empirically validate the impacts of newsworthiness on audience reactions. This study challenged to summarize the concepts of newsworthiness and validate the impact of representativeness of both editor's and audience's perspective on audience reactions as perceived news quality, trust on news portal, perceived usefulness, service satisfaction, loyalty, continuous usage intention, and word-of-mouth intention by adopting the representativeness heuristics method and information adoption model. 357 valid data had been collected using a scenario survey method. Subjects in each groups are exposed by 3 news recommendation mechanisms: 1) the time-priority news exposure mechanism (control group), 2) the reference-score-based news recommendation mechanism (a single treatment group), and 3) the major-news-priority exposure mechanism sorting by the reference scores made by peer audiences (the mixed treatment group). Data had been analyzed by the MANOVA and PLS method. MANOVA results indicate that only mixed method of both editor and audience recommendation mechanisms impacts on perceived news quality and trust. PLS results indicate that perceived news quality and trust could significantly affect on the perceived usefulness, service satisfaction, loyalty, continuance usage, and word-of-mouth intention. This study would contributions to empathize the role of information technology in media industry, to conceptualize the news value in the balanced views of both editors and audiences, and to empirically validate the benefits of news recommendation mechanisms in academy. For practice, the results of this study suggest that online news portals would be better to make mixed news recommendation mechanisms to attract audiences.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.30 no.2
• /
• pp.287-304
• /
• 2020

There have been a number of legal & policy studies on the affecting factors of big data utilization, but empirical research on the composition factors of personal information regulation or data combination, which acts as a constraint, has been hardly done due to the lack of relevant statistics. Therefore, this study empirically explores the priority of personal information regulation factors and data combination factors that influence big data utilization through Delphi Analysis. As a result of Delphi analysis, personal information regulation factors include in order of the introduction of pseudonymous information, evidence clarity of personal information de-identification, clarity of data combination regulation, clarity of personal information definition, ease of personal information consent, integration of personal information supervisory authority, consistency among personal information protection acts, adequacy punishment intensity in case of violation of law, and proper penalty level when comparing EU GDPR. Next, data combination factors were examined in order of de-identification of data combination, standardization of combined data, responsibility of data combination, type of data combination institute, data combination experience, and technical value of data combination. These findings provide implications for which policy tasks should be prioritized when designing personal information regulations and data combination policies to utilize big data.

• Journal of Digital Convergence
• /
• v.9 no.2
• /
• pp.111-129
• /
• 2011

Nowadays, the IS project is getting more and more complicated and large-scaled. Many researchers and practitioners are interested in the IS development methodologies, automated tools and techniques to decrease project failure and to increase IS project performance. This research is to seize the management level of PMO affecting on the IS project, as a new method to increase the IS project development performance. As a result of surveying the present PMO operation state with banks which are the leading industry to accept the PMO in Korea, technology support management and infrastructure management are the core functions to affect the IS performance including schedule management, quality management, and user and stakeholders' satisfaction. Also, the PMO management level is the important point of IS project success. Among the 5 levels PMI suggested, PMO can implement the project effectively at least at the third level. Korean companies introducing the PMO have to do research the PMO core functions and the management levels according to the project scale, and review the distinctive features of their organization to increase the maturity of IS project. This research has been proved through the Full Structural Equation Model. The results show that the five core functions of PMO have relationship with the IS project performance.

• Environmental and Resource Economics Review
• /
• v.33 no.2
• /
• pp.113-133
• /
• 2024

Variable renewable energy (VRE) such as solar and wind power is the main sources of achieving carbon net zero, but it undermines the stability of power supply due to high variability and uncertainty. Energy storage system (ESS) can not only reduce the curtailment of VRE by load shifting but also contribute to stable power system operation by providing ancillary services. This study analyzes how the allocation of ESS resources between load shifting and ancillary service can contribute to maximizing the efficiency of power supply in a situation where the problems caused by VRE are becoming more and more serious. A stochastic power system optimization model that can realistically simulate the variability and uncertainty of VRE was applied. The analysis time point was set to 2023 and 2036, and the optimal resource allocation strategy and benefits of ESS by varying VRE penetration levels were analyzed. The analysis results can be largely summarized into the following three. First, ESS provides excellent functions for both load shifting and ancillary service, and it was confirmed that the higher the reserve price, the more limited the load shifting and focused on providing reserve. Second, the curtailment of VRE can be a effective substitute for the required reserve, and the higher the reserve price level, the higher the curtailment of VRE and the lower the required amount of reserve. Third, if a reasonable reserve offer price reflecting the opportunity cost is applied, ESS can secure economic feasibility in the near future, and the higher the proportion of VRE, the greater the economic feasibility of ESS. This study suggests that cost-effective low-carbon transition in the power system is possible when the price signal is correctly designed so that power supply resources can be efficiently utilized.

• 한국정보교육학회:학술대회논문집
• /
• 2005.08a
• /
• pp.314-321
• /
• 2005

교육정보화 사업은 제 1, 2단계 교육정보화 종합발전 방안의 큰 틀 안에서 성공적으로 추진되어 왔다. 제 1단계 교육정보화 종합 계획에서 물적 기반 구축을 중심으로 이루어지던 교육정보화 정책이 2001년부터 시행된 제 2단계 교육정보화 종합 발전 방안에서는 활용 중심의 교육정보화 방향으로 전환하여 수행되어 왔다. 제 2단계 교육정보화 종합 발전방안이 종료되는 2005년 현 시점에서 돌이켜 보면, 교육정보화 인프라 구축 및 물량 투입 중심의 정보화 사업을 추진해 왔으며 그 결과 다른 여러 나라와 비교해서 손색이 없을 정도로 교육 현장에 정보화 환경이 조성되고 있고, 교육정보화를 통한 교육 혁신의 중요성을 인식하고 있다. 그러나 현재 학교에 보급된 교육정보자원은 학교마다의 실정을 고려하지 않은 대부분 공급자 중심의 획일화 된 규격에 일부 자원의 경우 여러 가지 이유로 충분한 활용이 이뤄지지 못하고 있다. 또, 교육정보자원의 관리 측면에서는 관리 주체가 학교마다 다르고 제대로 지정되지 않은 경우도 많아 업무의 효율성과 관리의 용이성이 떨어지고 있다. 따라서 본 연구에서는 10 여 년 동안 일선 학교에 보급된 교육정보자원을 보다 효과적으로 운영하기 위해서 현재 교육정보자원에 대한 활용, 관리 실태를 정확하게 파악하고, 조사 분석을 통해 문제점을 도출하고 이를 토대로 교육정보자원의 내실화 방안을 수립하여 제반 교육정보자원의 역할 및 기능을 재정립하고, 향후 신기술 수용 및 교육환경 변화에 능동적으로 대처할 수 있도록 하고자 한다.

• The Journal of the Korea Contents Association
• /
• v.17 no.4
• /
• pp.350-364
• /
• 2017

The purpose of this study was to understand and describe the demand of applying an anger management program for university students, based on professor-student counseling activity. 2016, data was collected using five focus group interviews were recorded and transcribed. All interviews were recorded and transcribed, and data were analyzed using qualitative content analysis. We extracted the following 9 categories across 3 main themes: 1) Views on applying an anger management program based on professor-student counseling activity: required or not required; 2) Competence of the professor: trust, counseling expertise, and receptive attitude; and 3) Effective program management plans: separation from the advisor or reducing the role of the advisor, program composition and contents, administrative support from the university, facilitating a supportive environment for counseling. In conclusion, enhancement can be achieved through an anger management program based on professor-student counseling activity by focusing efforts on increasing interactions between professors and students, and improving the counseling competence of professors. Additionally, administrative support from the university and steps to improve awareness in professors, students, and university authorities are necessary.

• Journal of Korean Library and Information Science Society
• /
• v.47 no.4
• /
• pp.559-578
• /
• 2016

According to the rapid increase of foreign immigrants, South Korea recently has grown more and more interested in the acceptance of cultural diversity in diverse fields at the whole society. Korea Library Association also has sought the way of multicultural service for foreign immigrants in libraries and many previous researches has suggested those. This paper examines the ways in which small community library functions for foreign immigrants, analyzing on the case of multicultural library located in Wongok-dong, Ansan-si, where about 80% population of residents are foreign immigrants. Ansan multicultural library has two functions in the community. One is the educational place for helping immigrants' settlement and adaptation of South Korea. The other is the cultural place for social integration between immigrants and South Koreans based on mutual understanding and communication. Ultimately this paper shows how values small library in the community has significantly for foreign immigrants.

• Journal of Ginseng Research
• /
• v.33 no.1
• /
• pp.1-7
• /
• 2009

Clinical and animal studies have shown that free radical overload is an important cause for a variety of diseases. Although ginseng has been recognized as antioxidant, how it modulates anti-oxidative process at the molecular level remains unknown. Free radical production is induced by tumor necrosis factor-$\alpha$ (TNF-$\alpha$) under the stress condition, and (TNF-$\alpha$) release is activated by TNF-$\alpha$-converting enzyme (TACE). Since TACE inhibitor is also well known for anti-inflammatory agent, ginseng seems to show anti-oxidative activity by repressing TACE pathway. Further studies on signal transduction would be warranted to elucidate molecular action mechanisms of ginseng on anti-oxidation and anti-inflammation.