• Journal of the Korean Society of Propulsion Engineers
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• v.17 no.4
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• pp.10-15
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• 2013

For design optimization, engineers should require the accurate information of design space and then explore the design space and carry out optimization. Recently, the total design framework, based on design of experiments and optimization, is widely used in industry areas to explore the design space above all. For optimizing turbofan engine design point, the response surface model is constructed by using the 7 level orthogonal array which satisfies the statistical uniformity and orthogonality and gets the dense design space information. The multi-objective genetic algorithm is used to find the optimal solution within the given constraints for finding global optimal one in response surface model. The optimal solution from response surface model is verified with GasTurb simulation result.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2007.11a
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• pp.133-134
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• 2007

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2007.04a
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• pp.22-23
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• 2007

3차원 모델이 가능한 전산유체역학에 기초를 둔 유체 플라즈마 모델링 소프트웨어가 플라즈마 장치 개발에 어떤 도움을 줄 수 있을 것인지 고찰하였다. 몇 가지의 유도 결합 플라즈마용 안테나 구조와 유동의 역할, 공간 및 표면 화학반응의 결과에 대한 자동 최적화 계산의 유용성에 대해서 논한다.

• Journal of Acupuncture Research
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• v.20 no.3
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• pp.104-116
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• 2003

목적 : 시스테인 단백분해 효소인 cathepsin는 인간과 생쥐의 항원제시세포에서 II형 주적합항원 불변사슬(MHC class II invariant chain)의 분해에 관여한다. 본 연구는 녹용 약침액이 류마티스 관절염 생쥐 모델의 골조직(연골과 활액) 유래 cathepsin 활성에 미치는 영향을 검정하였다. 방법 : 관절염 동물모델은 BALb/c계 생쥐를 생후 3일에 흉선 적출(3d-Tx)을 하여 만들었다. 동물모델의 골조직, 임파절세포, 비장 등을 녹용처치군과 대조군으로 나누어 cathepsin의 활성도 및 자가항원 특이(C-II-specific) T-세포의 활성도를 비교 분석하였다. 결과 : 각 장기에서 cathepsin S의 활성은 녹용약침 처치군에서 농도 의존적으로 유의성 있게 억제되었고, T-세포 특이 자가항원반응은 녹용약침 처치군의 임파절 세포에서 유의성있게 억제되었다. 그리고 T-세포 특이 자가항원 반응의 불활성화에는 녹용 10~20ug/ml의 용량으로 충분하였다. 결론 : 이러한 실험결과는 녹용 약침액이 cathepsin S를 선택적으로 억제시켜 류마티스 관절염과 같은 자가면역 질환에 유효한 치료약물로 사용될 수 있음을 시사한다.

• Journal of the Korean GEO-environmental Society
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• v.16 no.5
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• pp.5-11
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• 2015

The double sheeted permeable reactive barrier containing two different reactive materials can be applied to remediate the groundwater contaminated by nutrients and heavy metals. In this study, in order to evaluate the removal efficiency of contaminants including ammonium, cadmium and phosphate by double layered permeable reactive barrier containing zeolite and steelmaking slag, column tests were performed. In addition, nonequilibrium reaction in column tests was analyzed by two-site nonequilibrium advection-dispersion model. Column test results showed that zeolite is effective for removal of ammonium, while steelmaking slag is effective for removal of phosphate and cadmium. The sequential reaction of zeolite and steelmaking slag gave the better removal efficiency for ammonium.

• Archives of design research
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• v.14 no.3
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• pp.37-48
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• 2001

This paper is a study on how women consumers purchase are affected by models who appear in advertisements for cosmetics, focusing especially on studies concerning the impact that models have on advertisement strategies of the cosmetic industry in korea. In surveys conducted, consumers responded that cosmetic advertisement models should examplify a expertness and trustworthiness attitude more than just display their own physical attractiveness. The consumers who bought cosmetic products based on its endorsement from particular models responded that they had a positive reaction to the models physical attractiveness and likability while experiencing a negative reaction to the model's expertness and trustworthiness attitude. Women consumers are interested in cosmetic advertisement models, but do not necessarily trust them. Hence, the use of a Particular model does not directly affect the consumers Purchasing decision. Famous stars often appear in cosmetic advertisements in korea, and targeted consumers have a very positive response to their physical attractiveness, familiarity and perceived likability. However, the consumers have a completely negative response to the models in regards to their expertness, trustworthiness, and their sense of similarity with the model. The models, then, should be used in these advertisements to try and uphold the fellowing qualities. expertness in regards to having some knowledge of, experience with, and expertness in using the cosmetic produces, trustworthiness when expressing their own opinion of the product, matching image of products and targeted consumers.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.9
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• pp.1305-1310
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• 2010

In a practical design process, the method of extracting the design space information of the complex system for verifying, improving, and optimizing the design process by taking into account the design variables and their shape tolerance is very important. Finite element analysis has been successfully implemented and integrated with design of experiment such as D-Optimal array; thus, a response surface model and optimization tools have been obtained, and design variables can be optimized by using the model and these tools. Then, to guarantee the robustness of the design variables, a robust design should be additionally performed by taking into account the statistical variation of the shape tolerance of the optimized design variables. In this study, a new approach based on the use of the response surface model is proposed; in this approach, the standard normal distribution of the shape tolerance is considered. By adopting this approach, it is possible to simultaneously optimize variables and perform a robust design. This approach can serve as a means of efficiently modeling the trade-off among many conflicting goals in the applications of finite element analysis. A case study on the robust optimal design of disc brakes under thermal loadings was carried out to solve multiple objective functions and determine the constraints of the design variables, such as a thermal deformation and weight.

• The Journal of Korean Society of Virology
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• v.27 no.1
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• pp.19-27
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• 1997

To develop the polymerase chain reaction (PCR) for the detection of type D simian retrovirus (SRV) infection, an oligonucleotide primer pair was designed to hybridize to the sequences within env gene of SRV subtype 1 (SRV-1). The 3' proximal env sequences annealing to the primers had been rather conserved among three different subtypes of SRV, SRV-1, SRV-2, and SRV-3 (Mason-Pfizer Monkey Virus: MPMV). The PCR using the primer pair targeting an env region successfully detected and amplified all three subtypes of SRV with excellent specificity after single round of reaction. The tests with peripheral blood mononuclear cells infected either with simian immunodeficiency virus or simian T-Iymphotropic virus type 1, major immunosuppressive viral agents together with SRV in simian, verified the specificity of the PCR by excluding any cross reactivity. Semiquantitative titration PCR, amplifying serially diluted plasmid DNA of each subtype, was performed to evaluate sensitivity limits of the reaction. Based on molecular weight of each cloned SRV genome, the PCR should be able to detect one SRV-infected cell per more than $5-7{\times}10^4$ uninfected cells after simple ethidium bromide staining of resulting products. The PCR must be very efficient screening system with its quickness, certainty, and sensitivity for SRV-infected animals used in human AIDS research model. Second round amplification of the reaction products from the first PCR, or Southern hybridization by radiolabeled probes shall render to compete its efficacy to ELISA which has been the most sensitive technique to screen SRV infection but with frequent ambiguity problem.

• Journal of Soil and Groundwater Environment
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• v.10 no.3
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• pp.9-15
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• 2005

Soil aquifer treatment is a water reuse technology that secondary or tertiary treated wastewater is infiltrated into the aquifer in which physical and biochemical reactions occur. Major consideration in SAT is the removal and transport of DOC and nitrogen species. In this study, reaction mechanism in SAT was examined considering nitrification, denitrification and organic oxidation. In addition, SAT modeling system was developed as the reaction mechanism was applied to groundwater flow and transport model. In verification of the reaction module by 1-dimensional unsaturated soil column test, the experimental data of all of the species, ammonium, nitrate, DOC and DO, were well matched with the simulation results. In sensitivity analysis, ammonium partition coefficient, dissolved oxygen inhibition constant and biomass decay rate affect ammonium, DOC and DO concentration of effluent, respectively.

• Journal of the Korea Convergence Society
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• v.8 no.3
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• pp.23-30
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• 2017

OpenADR is a national standard communication protocol of demand response service. OpenADR uses XML message, called a payload, to support logical transaction of demand response service. For this purpose, OpenADR defines a XML element as transaction identifier which is called requestID. Unfortunately, OpenADR 2.0b profile specification describes some information about requestID but, it is not enough for understanding properly. Ambiguous definition of payload transaction makes vulnerabilities of implementing VEN & VTN and confuses mapping OpenADR 2.0b protocol into other smart grid protocols. Therefore, this paper redefines payload transaction to solve an ambiguous information of OpenADR 2.0b profile specification, proposes a model of analyzing payload transaction, and shows how to detect a payload transaction vulnerability in real-world.